List of works - Charles J. Dorman

1995 Flemming Lecture. DNA topology and the global control of bacterial gene expression: implications for the regulation of virulence gene expression.

scientific article

A Fundamental Regulatory Mechanism Operating through OmpR and DNA Topology Controls Expression of Salmonella Pathogenicity Islands SPI-1 and SPI-2 ⬇️

scientific article published on March 22, 2012

A Rho-dependent phase-variable transcription terminator controls expression of the FimE recombinase in Escherichia coli.

scientific article

A global role for Fis in the transcriptional control of metabolism and type III secretion in Salmonella enterica serovar Typhimurium.

scientific article

A novel genetic locus determines in vivo B-Z DNA structural transitions in Escherichia coli.

scientific article

A novel role for antibiotic resistance plasmids in facilitating Salmonella adaptation to non-host environments.

scientific article published on 12 September 2013

A role for the leucine-responsive regulatory protein and integration host factor in the regulation of the Salmonella plasmid virulence (spv ) locus in Salmonella typhimurium

scientific article published in October 1999

Activity of a plasmid-borne leu-500 promoter depends on the transcription and translation of an adjacent gene ⬇️

scientific article published on September 15, 1992

Agnès Fouet - departing Editor-in-Chief

scientific article published on 01 June 2015

An H-NS-like stealth protein aids horizontal DNA transmission in bacteria

scientific article published in January 2007

An extended role for the nucleoid structuring protein H-NS in the virulence gene regulatory cascade of Shigella flexneri

scientific article published on 01 February 2003

An overlap between osmotic and anaerobic stress responses: a potential role for DNA supercoiling in the coordinate regulation of gene expression

scientific article published in July 1989

Anti-silencing: overcoming H-NS-mediated repression of transcription in Gram-negative enteric bacteria

scientific article published on September 2008

Autoregulated expression of the gene coding for the leucine-responsive protein, Lrp, a global regulator in Salmonella enterica serovar Typhimurium.

scientific article published in July 2008

Bacterial DNA topology and infectious disease.

scientific article published on 10 December 2008

Bacterial regulon evolution: distinct responses and roles for the identical OmpR proteins of Salmonella Typhimurium and Escherichia coli in the acid stress response

scientific article (publication date: March 2014)

Broad-scale redistribution of mRNA abundance and transcriptional machinery in response to growth rate in Salmonella enterica serovar Typhimurium.

scientific article published on 4 August 2017

Characterization of the detachable Rho-dependent transcription terminator of the fimE gene in Escherichia coli K-12

scientific article published on December 2005

Chromosome rearrangements induced by recombinant coliphage lambda placMu.

scientific article

Compensatory evolution of gene regulation in response to stress by Escherichia coli lacking RpoS.

scientific article published on 2 October 2009

Consequences of producing DNA gyrase from a synthetic gyrBA operon in Salmonella enterica serovar Typhimurium

scientific article published on 27 February 2021

Control of Escherichia coli type 1 fimbrial gene expression in stationary phase: a negative role for RpoS.

scientific article

Coupling of Escherichia coli hns mRNA levels to DNA synthesis by autoregulation: implications for growth phase control

scientific article published on 01 October 1995

DNA relaxation-dependent phase biasing of the fim genetic switch in Escherichia coli depends on the interplay of H-NS, IHF and LRP.

scientific article published on 2 November 2009

DNA sequence heterogeneity in Fim tyrosine-integrase recombinase-binding elements and functional motif asymmetries determine the directionality of the fim genetic switch in Escherichia coli K-12.

scientific article published on 20 November 2007

DNA supercoiling and bacterial gene expression.

scientific article published on January 2006

DNA supercoiling and the Lrp protein determine the directionality of fim switch DNA inversion in Escherichia coli K-12.

scientific article published on August 2006

DNA supercoiling and the anaerobic and growth phase regulation of tonB gene expression.

scientific article

DNA supercoiling and transcription in bacteria: a two-way street

scientific article published on 18 July 2019

DNA supercoiling in Escherichia coli: topA mutations can be suppressed by DNA amplifications involving the tolC locus

scientific article published on 01 April 1989

DNA supercoiling is differentially regulated by environmental factors and FIS in Escherichia coli and Salmonella enterica

scientific article published on 15 February 2011

DNA topology and adaptation of Salmonella typhimurium to an intracellular environment.

scientific article published in May 2000

DNA topology and bacterial virulence gene regulation.

scientific article

Differential regulation of the plasmid-encoded genes in the Shigella flexneri virulence regulon

scientific article published on 01 September 1997

Domain organization and oligomerization among H-NS-like nucleoid-associated proteins in bacteria.

scientific article

Effects of local transcription and H-NS on inversion of the fim switch of Escherichia coli.

scientific article published in April 2000

Environmentally constrained mutation and adaptive evolution in Salmonella

scientific article

Escherichia coli tyrT gene transcription is sensitive to DNA supercoiling in its native chromosomal context: effect of DNA topoisomerase IV overexpression on tyrT promoter function

scientific article published on October 1994

Expression of the Fis protein is sustained in late-exponential- and stationary-phase cultures of Salmonella enterica serovar Typhimurium grown in the absence of aeration

scientific article published on 3 September 2007

Fimbrial phase variation in Escherichia coli: dependence on integration host factor and homologies with other site-specific recombinases

scientific article

Flexible response: DNA supercoiling, transcription and bacterial adaptation to environmental stress.

scientific article published on June 1996

Function of nucleoid-associated proteins in chromosome structuring and transcriptional regulation

scientific article

Functional analysis of the FimE integrase of Escherichia coli K-12: isolation of mutant derivatives with altered DNA inversion preferences

scientific article published on 01 December 1999

Genome architecture and global gene regulation in bacteria: making progress towards a unified model? ⬇️

scientific article published on 03 April 2013

Genome-wide analysis of the H-NS and Sfh regulatory networks in Salmonella Typhimurium identifies a plasmid-encoded transcription silencing mechanism

scientific article

Global regulators and environmental adaptation in Gram-negative pathogens.

scientific article published on January 2009

H-NS and genomic bridge building: lessons from the human pathogen Salmonella Typhi

scientific article

H-NS antagonism in Shigella flexneri by VirB, a virulence gene transcription regulator that is closely related to plasmid partition factors.

scientific article published on 16 February 2007

H-NS silences gfp, the green fluorescent protein gene: gfpTCD is a genetically Remastered gfp gene with reduced susceptibility to H-NS-mediated transcription silencing and with enhanced translation.

scientific article published on 16 July 2010

H-NS, the genome sentinel

scientific article published on 27 December 2006

H-NS-like nucleoid-associated proteins, mobile genetic elements and horizontal gene transfer in bacteria.

scientific article published on 03 July 2014

Hierarchical gene regulators adapt Salmonella enterica to its host milieus.

scientific article

Horizontally acquired homologues of the nucleoid-associated protein H-NS: implications for gene regulation

scientific article published on 09 December 2009

Human Health and Ocean Pollution

scientific article published on 03 December 2020

In Vivo DNA-Binding and Oligomerization Properties of the Shigella flexneri AraC-Like Transcriptional Regulator VirF as Identified by Random and Site-Specific Mutagenesis ⬇️

scientific article published on January 1, 2002

In vitro DNA-binding properties of VirB, the Shigella flexneri virulence regulatory protein

scientific article

In vivo analysis of the interactions of the LysR-like regulator SpvR with the operator sequences of the spvA and spvR virulence genes of Salmonella typhimurium

scientific article published in October 1998

Integrating small molecule signalling and H-NS antagonism in Vibrio cholerae, a bacterium with two chromosomes

scientific article published on 25 June 2015

Isolation and characterization of a topA mutant of Shigella flexneri

scientific article published in February 1993

LeuO is a global regulator of gene expression in Salmonella enterica serovar Typhimurium

scientific article published on 23 July 2012

Molecular dissection of VirB, a key regulator of the virulence cascade of Shigella flexneri.

scientific article published on 15 February 2002

Multicopy fimB gene expression in Escherichia coli: binding to inverted repeats in vivo, effect on fimA gene transcription and DNA inversion

scientific article published on September 1996

Negative supercoiling of DNA by gyrase is inhibited in Salmonella enterica serovar Typhimurium during adaptation to acid stress.

scientific article published on 20 January 2018

Nonenzymatic chloramphenicol resistance determinants specified by plasmids R26 and R55-1 in Escherichia coli K-12 do not confer high-level resistance to fluorinated analogs.

scientific article published on November 1982

Nucleoid-associated proteins and bacterial physiology.

scientific article published on January 2009

Nucleotide sequence of the R26 chloramphenicol resistance determinant and identification of its gene product

scientific article published in January 1986

Osmotic and growth-phase dependent regulation of the eta gene of Staphylococcus aureus: a role for DNA supercoiling

scientific article published on 01 March 1992

Overexpression of the Shigella flexneri genes coding for DNA topoisomerase IV compensates for loss of DNA topoisomerase I: effect on virulence gene expression

scientific article published in February 1995

Positive regulation of Shigella flexneri virulence genes by integration host factor.

scientific article

Probing bacterial nucleoid structure with optical tweezers

scientific article published in March 2007

Rational Design of an Artificial Genetic Switch: Co-Option of the H-NS-Repressed proU Operon by the VirB Virulence Master Regulator ⬇️

scientific article published on August 26, 2011

Re-engineering cellular physiology by rewiring high-level global regulatory genes.

scientific article published on 3 December 2015

Regulation of gene expression by histone-like proteins in bacteria.

scientific article

Regulation of transcription by DNA supercoiling in Mycoplasma genitalium: global control in the smallest known self-replicating genome

scientific article published on 16 June 2011

Requirement for the molecular adapter function of StpA at the Escherichia coli bgl promoter depends upon the level of truncated H-NS protein

scientific article published on 01 November 2001

Role of hns in the virulence phenotype of pathogenic salmonellae

scientific article published on July 1994

Role of ompR-dependent genes in Salmonella typhimurium virulence: mutants deficient in both ompC and ompF are attenuated in vivo ⬇️

scientific article published on January 1, 1991

Roles for DNA supercoiling and the Fis protein in modulating expression of virulence genes during intracellular growth of Salmonella enterica serovar Typhimurium.

scientific article published on 25 September 2006

Sequence-imposed structural constraints in the TonB protein of E. coli.

scientific article

Small molecule signaling

scientific article published on 9 March 2009

Structure and function of X-Pro dipeptide repeats in the TonB proteins of Salmonella typhimurium and Escherichia coli.

scientific article published in December 1990

The DNA supercoiling-sensitive expression of the Salmonella typhimurium his operon requires the his attenuator and is modulated by anaerobiosis and by osmolarity

scientific article

The Escherichia coli stpA gene is transiently expressed during growth in rich medium and is induced in minimal medium and by stress conditions.

scientific article

The Shigella virulence gene regulatory cascade: a paradigm of bacterial gene control mechanisms

scientific article published on 01 August 1998

The StpA Protein Functions as a Molecular Adapter To Mediate Repression of the bgl Operon by Truncated H-NS in Escherichia coli ⬇️

scientific article published on February 1, 1998

The VirF protein from Shigella flexneri is a member of the AraC transcription factor superfamily and is highly homologous to Rns, a positive regulator of virulence genes in enterotoxigenic Escherichia coli

scientific article published in June 1992

The effect of mobile element IS10 on experimental regulatory evolution in Escherichia coli

scientific article published on 16 April 2010

The gyr genes of Salmonella enterica serovar Typhimurium are repressed by the factor for inversion stimulation, Fis.

scientific article

The integration host factor (IHF) integrates stationary-phase and virulence gene expression in Salmonella enterica serovar Typhimurium.

scientific article published on March 2006

The interplay between DNA topology and accessory factors in site-specific recombination in bacteria and their bacteriophages.

scientific article

The leucine-responsive regulatory protein, Lrp, activates transcription of the fim operon in Salmonella enterica serovar typhimurium via the fimZ regulatory gene.

scientific article

The site-specific recombination system regulating expression of the type 1 fimbrial subunit gene of Escherichia coli is sensitive to changes in DNA supercoiling

scientific article published in December 1994

The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium.

scientific article

The virulence plasmid of Salmonella typhimurium contains an autoregulated gene, rlgA, that codes for a resolvase-like DNA binding protein

scientific article

Thermal regulation of fimA, the Escherichia coli gene coding for the type 1 fimbrial subunit protein

scientific article published in December 1992

Thinking and decision making, bacterial style: Bacterial Neural Networks, Obernai, France, 7th-12th June 2002.

scientific article

Three-way interactions among the Sfh, StpA and H-NS nucleoid-structuring proteins of Shigella flexneri 2a strain 2457T

scientific article published on 01 June 2003

Transcription of the Salmonella typhimurium spv virulence locus is regulated negatively by the nucleoid-associated protein H-NS.

scientific article published in August 1994

Transmission of an oxygen availability signal at the Salmonella enterica serovar Typhimurium fis promoter

scientific article

Two highly related regulatory proteins, Shigella flexneri VirF and enterotoxigenic Escherichia coli Rns, have common and distinct regulatory properties.

scientific article published in May 1998

Use of the stationary phase inducible promoters, spv and dps, to drive heterologous antigen expression in Salmonella vaccine strains

scientific article

VirB-mediated positive feedback control of the virulence gene regulatory cascade of Shigella flexneri.

scientific article published on 20 July 2012

Virulence Gene Regulation in Shigella

scientific article published in December 2004

Virulence gene deletion frequency is increased in Shigella flexneri following conjugation, transduction, and transformation

scientific article published on 01 February 1997

List of works by Charles J. Dorman

1995 Flemming Lecture. DNA topology and the global control of bacterial gene expression: implications for the regulation of virulence gene expression.

A Fundamental Regulatory Mechanism Operating through OmpR and DNA Topology Controls Expression of Salmonella Pathogenicity Islands SPI-1 and SPI-2 ⬇️

A Rho-dependent phase-variable transcription terminator controls expression of the FimE recombinase in Escherichia coli.

A global role for Fis in the transcriptional control of metabolism and type III secretion in Salmonella enterica serovar Typhimurium.

A novel genetic locus determines in vivo B-Z DNA structural transitions in Escherichia coli.

A novel role for antibiotic resistance plasmids in facilitating Salmonella adaptation to non-host environments.

A role for the leucine-responsive regulatory protein and integration host factor in the regulation of the Salmonella plasmid virulence (spv ) locus in Salmonella typhimurium

Activity of a plasmid-borne leu-500 promoter depends on the transcription and translation of an adjacent gene ⬇️

Agnès Fouet - departing Editor-in-Chief

An H-NS-like stealth protein aids horizontal DNA transmission in bacteria

An extended role for the nucleoid structuring protein H-NS in the virulence gene regulatory cascade of Shigella flexneri

An overlap between osmotic and anaerobic stress responses: a potential role for DNA supercoiling in the coordinate regulation of gene expression

Anti-silencing: overcoming H-NS-mediated repression of transcription in Gram-negative enteric bacteria

Autoregulated expression of the gene coding for the leucine-responsive protein, Lrp, a global regulator in Salmonella enterica serovar Typhimurium.

Bacterial DNA topology and infectious disease.

Bacterial regulon evolution: distinct responses and roles for the identical OmpR proteins of Salmonella Typhimurium and Escherichia coli in the acid stress response

Broad-scale redistribution of mRNA abundance and transcriptional machinery in response to growth rate in Salmonella enterica serovar Typhimurium.

Characterization of the detachable Rho-dependent transcription terminator of the fimE gene in Escherichia coli K-12

Chromosome rearrangements induced by recombinant coliphage lambda placMu.

Compensatory evolution of gene regulation in response to stress by Escherichia coli lacking RpoS.

Consequences of producing DNA gyrase from a synthetic gyrBA operon in Salmonella enterica serovar Typhimurium

Control of Escherichia coli type 1 fimbrial gene expression in stationary phase: a negative role for RpoS.

Coupling of Escherichia coli hns mRNA levels to DNA synthesis by autoregulation: implications for growth phase control

DNA relaxation-dependent phase biasing of the fim genetic switch in Escherichia coli depends on the interplay of H-NS, IHF and LRP.

DNA sequence heterogeneity in Fim tyrosine-integrase recombinase-binding elements and functional motif asymmetries determine the directionality of the fim genetic switch in Escherichia coli K-12.

DNA supercoiling and bacterial gene expression.

DNA supercoiling and the Lrp protein determine the directionality of fim switch DNA inversion in Escherichia coli K-12.

DNA supercoiling and the anaerobic and growth phase regulation of tonB gene expression.

DNA supercoiling and transcription in bacteria: a two-way street

DNA supercoiling in Escherichia coli: topA mutations can be suppressed by DNA amplifications involving the tolC locus

DNA supercoiling is differentially regulated by environmental factors and FIS in Escherichia coli and Salmonella enterica

DNA topology and adaptation of Salmonella typhimurium to an intracellular environment.

DNA topology and bacterial virulence gene regulation.

Differential regulation of the plasmid-encoded genes in the Shigella flexneri virulence regulon

Domain organization and oligomerization among H-NS-like nucleoid-associated proteins in bacteria.

Effects of local transcription and H-NS on inversion of the fim switch of Escherichia coli.

Environmentally constrained mutation and adaptive evolution in Salmonella

Escherichia coli tyrT gene transcription is sensitive to DNA supercoiling in its native chromosomal context: effect of DNA topoisomerase IV overexpression on tyrT promoter function

Expression of the Fis protein is sustained in late-exponential- and stationary-phase cultures of Salmonella enterica serovar Typhimurium grown in the absence of aeration

Fimbrial phase variation in Escherichia coli: dependence on integration host factor and homologies with other site-specific recombinases

Flexible response: DNA supercoiling, transcription and bacterial adaptation to environmental stress.

Function of nucleoid-associated proteins in chromosome structuring and transcriptional regulation

Functional analysis of the FimE integrase of Escherichia coli K-12: isolation of mutant derivatives with altered DNA inversion preferences

Genome architecture and global gene regulation in bacteria: making progress towards a unified model? ⬇️

Genome-wide analysis of the H-NS and Sfh regulatory networks in Salmonella Typhimurium identifies a plasmid-encoded transcription silencing mechanism

Global regulators and environmental adaptation in Gram-negative pathogens.

H-NS and genomic bridge building: lessons from the human pathogen Salmonella Typhi

H-NS antagonism in Shigella flexneri by VirB, a virulence gene transcription regulator that is closely related to plasmid partition factors.

H-NS silences gfp, the green fluorescent protein gene: gfpTCD is a genetically Remastered gfp gene with reduced susceptibility to H-NS-mediated transcription silencing and with enhanced translation.

H-NS, the genome sentinel

H-NS-like nucleoid-associated proteins, mobile genetic elements and horizontal gene transfer in bacteria.

Hierarchical gene regulators adapt Salmonella enterica to its host milieus.

Horizontally acquired homologues of the nucleoid-associated protein H-NS: implications for gene regulation

Human Health and Ocean Pollution

In Vivo DNA-Binding and Oligomerization Properties of the Shigella flexneri AraC-Like Transcriptional Regulator VirF as Identified by Random and Site-Specific Mutagenesis ⬇️

In vitro DNA-binding properties of VirB, the Shigella flexneri virulence regulatory protein

In vivo analysis of the interactions of the LysR-like regulator SpvR with the operator sequences of the spvA and spvR virulence genes of Salmonella typhimurium

Integrating small molecule signalling and H-NS antagonism in Vibrio cholerae, a bacterium with two chromosomes

Isolation and characterization of a topA mutant of Shigella flexneri

LeuO is a global regulator of gene expression in Salmonella enterica serovar Typhimurium

Molecular dissection of VirB, a key regulator of the virulence cascade of Shigella flexneri.

Multicopy fimB gene expression in Escherichia coli: binding to inverted repeats in vivo, effect on fimA gene transcription and DNA inversion

Negative supercoiling of DNA by gyrase is inhibited in Salmonella enterica serovar Typhimurium during adaptation to acid stress.

Nonenzymatic chloramphenicol resistance determinants specified by plasmids R26 and R55-1 in Escherichia coli K-12 do not confer high-level resistance to fluorinated analogs.

Nucleoid-associated proteins and bacterial physiology.

Nucleotide sequence of the R26 chloramphenicol resistance determinant and identification of its gene product

Osmotic and growth-phase dependent regulation of the eta gene of Staphylococcus aureus: a role for DNA supercoiling

Overexpression of the Shigella flexneri genes coding for DNA topoisomerase IV compensates for loss of DNA topoisomerase I: effect on virulence gene expression

Positive regulation of Shigella flexneri virulence genes by integration host factor.

Probing bacterial nucleoid structure with optical tweezers

Rational Design of an Artificial Genetic Switch: Co-Option of the H-NS-Repressed proU Operon by the VirB Virulence Master Regulator ⬇️

Re-engineering cellular physiology by rewiring high-level global regulatory genes.

Regulation of gene expression by histone-like proteins in bacteria.

Regulation of transcription by DNA supercoiling in Mycoplasma genitalium: global control in the smallest known self-replicating genome

Requirement for the molecular adapter function of StpA at the Escherichia coli bgl promoter depends upon the level of truncated H-NS protein

Role of hns in the virulence phenotype of pathogenic salmonellae

Role of ompR-dependent genes in Salmonella typhimurium virulence: mutants deficient in both ompC and ompF are attenuated in vivo ⬇️

Roles for DNA supercoiling and the Fis protein in modulating expression of virulence genes during intracellular growth of Salmonella enterica serovar Typhimurium.

Sequence-imposed structural constraints in the TonB protein of E. coli.