List of works - Bohdan Ostash

A gene cluster for the biosynthesis of moenomycin family antibiotics in the genome of teicoplanin producer Actinoplanes teichomyceticus ⬇️

scientific article published on 25 June 2016

A putative proteinase gene is involved in regulation of landomycin E biosynthesis in Streptomyces globisporus 1912

article

A streamlined metabolic pathway for the biosynthesis of moenomycin A.

scientific article published in March 2007

ABC transporter genes from Streptomyces ghanaensis moenomycin biosynthetic gene cluster: roles in antibiotic production and export ⬇️

scientific article published on 21 June 2012

An ABC transporter encoding gene lndW confers resistance to landomycin E.

scientific article published on 28 March 2008

Analysis of Streptomyces coelicolor M145 genes SCO4164 and SCO5854 encoding putative rhodaneses

scientific article

Analysis of Streptomyces ghanaensis ATCC14672 gene SSFG_07725 for putative γ-butyrolactone synthase

article

Bacterial transglycosylase inhibitors

scientific article published in October 2005

Characterization and analysis of the regulatory network involved in control of lipomycin biosynthesis in Streptomyces aureofaciens Tü117.

scientific article published on 8 July 2009

Characterization of Streptomyces globisporus 1912 lnd-cluster region containing lndY, lndYR, lndW2 and lndW genes

scientific article published in January 2013

Characterization of the Post-Assembly Line Tailoring Processes in Teicoplanin Biosynthesis.

scientific article published on 10 June 2016

Chemistry and biology of landomycins, an expanding family of polyketide natural products.

scientific article published on August 2009

Chemoenzymatic and bioenzymatic synthesis of carbohydrate containing natural products.

scientific article published on January 2010

Complete characterization of the seventeen step moenomycin biosynthetic pathway

scientific article published on September 2009

Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136.

scientific article published on 4 June 2008

Cultivable actinomycetes from rhizosphere of birch (Betula pendula) growing on a coal mine dump in Silets, Ukraine.

scientific article published on 17 May 2013

DNA-binding activity of LndI protein and temporal expression of the gene that upregulates landomycin E production in Streptomyces globisporus 1912.

scientific article

Decoding options and accuracy of translation of developmentally regulated UUA codon in Streptomyces: bioinformatic analysis

scientific article published on 04 July 2016

Development of a gene expression system for the uncommon actinomycete Actinoplanes rectilineatus NRRL B-16090

scientific article published on 07 January 2020

Diversity of genes encoding nonribosomal peptide synthetases in the Streptomyces sioyaensis genome

scientific article published on July 1, 2010

Effect of "ribosome engineering" on the transcription level and production of S. albus indigenous secondary metabolites

scientific article published on 19 July 2019

Eliciting the silent lucensomycin biosynthetic pathway in Streptomyces cyanogenus S136 via manipulation of the global regulatory gene adpA ⬇️

scientific article published on 10 February 2021

Evaluation of heterologous promoters for genetic analysis of Actinoplanes teichomyceticus--Producer of teicoplanin, drug of last defense.

scientific article published on 24 October 2013

Expression of the regulatory protein LndI for landomycin E production in Streptomyces globisporus 1912 is controlled by the availability of tRNA for the rare UUA codon

scientific article published in March 2006

Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis

scientific article published in November 2004

Function of lanI in regulation of landomycin A biosynthesis in Streptomyces cyanogenus S136 and cross-complementation studies with Streptomyces antibiotic regulatory proteins encoding genes

article

Gene miaA for post-transcriptional modification of tRNAXXA is important for morphological and metabolic differentiation in Streptomyces

scientific article published on 06 May 2019

Gene ssfg_01967 (miaB) for tRNA modification influences morphogenesis and moenomycin biosynthesis in Streptomyces ghanaensis ATCC14672

scientific article published on 13 December 2018

Generation and study of the strains of streptomycetes - heterologous hosts for production of moenomycin

scientific article

Generation of Streptomyces globisporus SMY622 strain with increased landomycin E production and it's initial characterization

scientific article

Generation of landomycin D-producing strain Streptomyces globisporus LD3

scientific article published on 01 January 2005

Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus

scientific article published on April 2004

Generation of novel landomycins M and O through targeted gene disruption

scientific article

Genes for biosynthesis of butenolide-like signalling molecules in Streptomyces ghanaensis, their role in moenomycin production.

scientific article

Genetic analysis of Streptomyces albus J1074 mia mutants suggests complex relationships between post-transcriptional tRNAXXA modifications and physiological traits

scientific article published on 17 July 2020

Genetic factors that influence moenomycin production in streptomycetes

scientific article

Genetic insights into the mechanism of teicoplanin self-resistance in Actinoplanes teichomyceticus

scientific article published on 17 January 2020

Genome Engineering Approaches to Improve Nosokomycin A Production by Streptomyces ghanaensis B38.3 ⬇️

scientific article published on 25 September 2018

Genomic Insights into Evolution of AdpA Family Master Regulators of Morphological Differentiation and Secondary Metabolism in Streptomyces.

scientific article published on 13 March 2018

Heterologous AdpA transcription factors enhance landomycin production in Streptomyces cyanogenus S136 under a broad range of growth conditions

scientific article published on 28 July 2018

Heterologous cross-expression of oxygenase and glycosyltransferase genes in streptomycetes, producing angucyclic antibiotics

scientific article published in May 2009

Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids. ⬇️

scientific article published on 22 January 2009

Identification and characterization of the Streptomyces globisporus 1912 regulatory gene lndYR that affects sporulation and antibiotic production.

scientific article

Identification of Streptomyces coelicolor M145 genomic region involved in biosynthesis of teichulosonic acid-cell wall glycopolymer

scientific article published on 06 February 2014

Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics.

scientific article

Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycin ⬇️

scientific article

IncP plasmids are most effective in mediating conjugation between Escherichia coli and streptomycetes.

scientific article

Influence of transition metals on Streptomyces coelicolor and S. sioyaensis and generation of chromate-reducing mutants.

scientific article published on 14 September 2013

Insights into naturally minimised Streptomyces albus J1074 genome. ⬇️

scientific article published on 05 February 2014

Landomycin biosynthesis and its regulation in Streptomyces

scientific article published on 11 January 2019

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

scientific article published on 9 December 2024

Manipulating the regulatory genes for teicoplanin production in Actinoplanes teichomyceticus

article

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

MoeH5: a natural glycorandomizer from the moenomycin biosynthetic pathway

scientific article

Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity ⬇️

scientific article published on August 23, 2010

Novel teichulosonic acid from cell wall of Streptomyces coelicolor M145.

scientific article published on 23 May 2012

On the acceptor substrate of C-glycosyltransferase UrdGT2: three prejadomycin C-Glycosides from an engineered mutant of Streptomyces globisporus 1912 DeltalndE(urdGT2).

scientific article

Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin

scientific article published on 23 October 2013

Production of landomycins in Streptomyces globisporus 1912 and S cyanogenus S136 is regulated by genes encoding putative transcriptional activators ⬇️

scientific article published in May 2003

Properties of Streptomyces albus J1074 mutant deficient in tRNALeuUAA gene bldA. ⬇️

scientific article published on 20 May 2017

Regulation of teicoplanin biosynthesis: refining the roles of tei cluster-situated regulatory genes

scientific article published on 01 April 2019

Role of GntR Family Regulatory Gene SCO1678 in Gluconate Metabolism in Streptomyces coelicolor M145.

scientific article

Site-specific recombinases in genetic engineering: modern in vivo technologies

scientific article published on July 1, 2010

Streptomyces ghanaensis pleiotropic regulatory gene wblA gh influences morphogenesis and moenomycin production

article

Structural Analysis of the Contacts Anchoring Moenomycin to Peptidoglycan Glycosyltransferases and Implications for Antibiotic Design

scientific article

TTA Lynx: a web-based service for analysis of actinomycete genes containing rare TTA codon

scientific article published on 2 July 2009

Targeted disruption of Streptomyces globisporus lndF and lndL cyclase genes involved in landomycin E biosynthesis

scientific article published in January 2003

Teicoplanin biosynthesis: unraveling the interplay of structural, regulatory, and resistance genes

scientific article published on 19 February 2020

Testing the utility of site-specific recombinases for manipulations of genome of moenomycin producer Streptomyces ghanaensis ATCC14672.

scientific article published on 24 March 2015

The adpA-like regulatory gene from Actinoplanes teichomyceticus: in silico analysis and heterologous expression

scientific article published on 4 June 2015

The molecular biology of moenomycins: towards novel antibiotics based on inhibition of bacterial peptidoglycan glycosyltransferases

scientific article published on May 2010

The pathway-specific regulatory genes, tei15* and tei16*, are the master switches of teicoplanin production in Actinoplanes teichomyceticus

scientific article published on 9 August 2014

Transcriptional regulators of GntR family in Streptomyces coelicolor A3(2): analysis in silico and in vivo of YtrA subfamily

scientific article published on 3 October 2015

[Gene networks that regulate secondary metabolism in actinomycetes: pleiotropic regulators]

[The use of PCR for detecting genes that encode type I polyketide synthases in genomes of actinomycetes]

scientific article

Über das Acceptorsubstrat der C-Glycosyltransferase UrdGT2: drei Prejadomycin-C-glycoside aus einer konstruierten Mutante vonStreptomyces globisporus 1912 ΔlndE(urdGT2)

scientific article published on 24 October 2006

List of works by Bohdan Ostash

A gene cluster for the biosynthesis of moenomycin family antibiotics in the genome of teicoplanin producer Actinoplanes teichomyceticus ⬇️

A putative proteinase gene is involved in regulation of landomycin E biosynthesis in Streptomyces globisporus 1912

A streamlined metabolic pathway for the biosynthesis of moenomycin A.

ABC transporter genes from Streptomyces ghanaensis moenomycin biosynthetic gene cluster: roles in antibiotic production and export ⬇️

An ABC transporter encoding gene lndW confers resistance to landomycin E.

Analysis of Streptomyces coelicolor M145 genes SCO4164 and SCO5854 encoding putative rhodaneses

Analysis of Streptomyces ghanaensis ATCC14672 gene SSFG_07725 for putative γ-butyrolactone synthase

Bacterial transglycosylase inhibitors

Characterization and analysis of the regulatory network involved in control of lipomycin biosynthesis in Streptomyces aureofaciens Tü117.

Characterization of Streptomyces globisporus 1912 lnd-cluster region containing lndY, lndYR, lndW2 and lndW genes

Characterization of the Post-Assembly Line Tailoring Processes in Teicoplanin Biosynthesis.

Chemistry and biology of landomycins, an expanding family of polyketide natural products.

Chemoenzymatic and bioenzymatic synthesis of carbohydrate containing natural products.

Complete characterization of the seventeen step moenomycin biosynthetic pathway

Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136.

Cultivable actinomycetes from rhizosphere of birch (Betula pendula) growing on a coal mine dump in Silets, Ukraine.

DNA-binding activity of LndI protein and temporal expression of the gene that upregulates landomycin E production in Streptomyces globisporus 1912.

Decoding options and accuracy of translation of developmentally regulated UUA codon in Streptomyces: bioinformatic analysis

Development of a gene expression system for the uncommon actinomycete Actinoplanes rectilineatus NRRL B-16090

Diversity of genes encoding nonribosomal peptide synthetases in the Streptomyces sioyaensis genome

Effect of "ribosome engineering" on the transcription level and production of S. albus indigenous secondary metabolites

Eliciting the silent lucensomycin biosynthetic pathway in Streptomyces cyanogenus S136 via manipulation of the global regulatory gene adpA ⬇️

Evaluation of heterologous promoters for genetic analysis of Actinoplanes teichomyceticus--Producer of teicoplanin, drug of last defense.

Expression of the regulatory protein LndI for landomycin E production in Streptomyces globisporus 1912 is controlled by the availability of tRNA for the rare UUA codon

Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis

Function of lanI in regulation of landomycin A biosynthesis in Streptomyces cyanogenus S136 and cross-complementation studies with Streptomyces antibiotic regulatory proteins encoding genes

Gene miaA for post-transcriptional modification of tRNAXXA is important for morphological and metabolic differentiation in Streptomyces

Gene ssfg_01967 (miaB) for tRNA modification influences morphogenesis and moenomycin biosynthesis in Streptomyces ghanaensis ATCC14672

Generation and study of the strains of streptomycetes - heterologous hosts for production of moenomycin

Generation of Streptomyces globisporus SMY622 strain with increased landomycin E production and it's initial characterization

Generation of landomycin D-producing strain Streptomyces globisporus LD3

Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus

Generation of novel landomycins M and O through targeted gene disruption

Genes for biosynthesis of butenolide-like signalling molecules in Streptomyces ghanaensis, their role in moenomycin production.

Genetic analysis of Streptomyces albus J1074 mia mutants suggests complex relationships between post-transcriptional tRNAXXA modifications and physiological traits

Genetic factors that influence moenomycin production in streptomycetes

Genetic insights into the mechanism of teicoplanin self-resistance in Actinoplanes teichomyceticus

Genome Engineering Approaches to Improve Nosokomycin A Production by Streptomyces ghanaensis B38.3 ⬇️

Genomic Insights into Evolution of AdpA Family Master Regulators of Morphological Differentiation and Secondary Metabolism in Streptomyces.

Heterologous AdpA transcription factors enhance landomycin production in Streptomyces cyanogenus S136 under a broad range of growth conditions

Heterologous cross-expression of oxygenase and glycosyltransferase genes in streptomycetes, producing angucyclic antibiotics

Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids. ⬇️

Identification and characterization of the Streptomyces globisporus 1912 regulatory gene lndYR that affects sporulation and antibiotic production.

Identification of Streptomyces coelicolor M145 genomic region involved in biosynthesis of teichulosonic acid-cell wall glycopolymer

Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics.

Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycin ⬇️

IncP plasmids are most effective in mediating conjugation between Escherichia coli and streptomycetes.

Influence of transition metals on Streptomyces coelicolor and S. sioyaensis and generation of chromate-reducing mutants.

Insights into naturally minimised Streptomyces albus J1074 genome. ⬇️

Landomycin biosynthesis and its regulation in Streptomyces

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

Manipulating the regulatory genes for teicoplanin production in Actinoplanes teichomyceticus

Minimum Information about a Biosynthetic Gene cluster.

MoeH5: a natural glycorandomizer from the moenomycin biosynthetic pathway

Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity ⬇️

Novel teichulosonic acid from cell wall of Streptomyces coelicolor M145.

On the acceptor substrate of C-glycosyltransferase UrdGT2: three prejadomycin C-Glycosides from an engineered mutant of Streptomyces globisporus 1912 DeltalndE(urdGT2).

Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin

Production of landomycins in Streptomyces globisporus 1912 and S cyanogenus S136 is regulated by genes encoding putative transcriptional activators ⬇️

Properties of Streptomyces albus J1074 mutant deficient in tRNALeuUAA gene bldA. ⬇️

Regulation of teicoplanin biosynthesis: refining the roles of tei cluster-situated regulatory genes

Role of GntR Family Regulatory Gene SCO1678 in Gluconate Metabolism in Streptomyces coelicolor M145.

Site-specific recombinases in genetic engineering: modern in vivo technologies

Streptomyces ghanaensis pleiotropic regulatory gene wblA gh influences morphogenesis and moenomycin production

Structural Analysis of the Contacts Anchoring Moenomycin to Peptidoglycan Glycosyltransferases and Implications for Antibiotic Design

TTA Lynx: a web-based service for analysis of actinomycete genes containing rare TTA codon

Targeted disruption of Streptomyces globisporus lndF and lndL cyclase genes involved in landomycin E biosynthesis

Teicoplanin biosynthesis: unraveling the interplay of structural, regulatory, and resistance genes

Testing the utility of site-specific recombinases for manipulations of genome of moenomycin producer Streptomyces ghanaensis ATCC14672.

The adpA-like regulatory gene from Actinoplanes teichomyceticus: in silico analysis and heterologous expression

The molecular biology of moenomycins: towards novel antibiotics based on inhibition of bacterial peptidoglycan glycosyltransferases

The pathway-specific regulatory genes, tei15* and tei16*, are the master switches of teicoplanin production in Actinoplanes teichomyceticus

Transcriptional regulators of GntR family in Streptomyces coelicolor A3(2): analysis in silico and in vivo of YtrA subfamily

[Gene networks that regulate secondary metabolism in actinomycetes: pleiotropic regulators]

[The use of PCR for detecting genes that encode type I polyketide synthases in genomes of actinomycetes]

Über das Acceptorsubstrat der C-Glycosyltransferase UrdGT2: drei Prejadomycin-C-glycoside aus einer konstruierten Mutante vonStreptomyces globisporus 1912 ΔlndE(urdGT2)