Search filters

List of works by Wilfried Rossoll

A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses.

scientific article published on 04 August 2016

A role for the survival of motor neuron protein in mRNP assembly and transport

scientific article published on 28 April 2016

Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells

scientific article

Characterization of Ighmbp2 in motor neurons and implications for the pathomechanism in a mouse model of human spinal muscular atrophy with respiratory distress type 1 (SMARD1)

scientific journal article

Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination

scientific article

Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons.

scientific article published on March 2016

Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA-binding protein IMP1 facilitates its trafficking into motor neuron axons

scientific article published on 04 October 2013

Dysregulation of mRNA Localization and Translation in Genetic Disease

scientific article

Gene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death

scientific article

Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons

scientific article published on August 2006

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

scientific article

PABPN1 suppresses TDP-43 toxicity in ALS disease models.

scientific article

Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS.

scientific article published in October 2017

Proximity proteomics of C9orf72 dipeptide repeat proteins identifies molecular chaperones as modifiers of poly-GA aggregation

scientific article published on 14 February 2022

Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons

scientific journal article

Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells

scholarly article

Spatially and temporally regulating translation via mRNA-binding proteins in cellular and neuronal function.

scientific article published on 10 March 2017

Spinal muscular atrophy and a model for survival of motor neuron protein function in axonal ribonucleoprotein complexes

scientific article published on January 2009

Spinal muscular atrophy: the role of SMN in axonal mRNA regulation.

scientific article

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.

scientific article published on 8 January 2018

The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.

scientific article

The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly

scientific article

The heterogeneous nuclear ribonucleoprotein-R is necessary for axonal beta-actin mRNA translocation in spinal motor neurons

scientific article published on 18 February 2010

The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn / mice and results in a mouse with spinal muscular atrophy

article

The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons.

scientific article

Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia

scientific article

Paulina is supported by:

About Paulina

Help