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List of works by Lezanne Ooi

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TRPV3 is a temperature-sensitive vanilloid receptor-like protein.

scientific article published on 23 June 2002
Chromatin crosstalk in development and disease: lessons from REST

scientific article
The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl- channels

scientific article
Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.

scientific article
Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication

scientific article published on 09 August 2006
Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury

scientific article published on 23 February 2011
Walking the tightrope: proteostasis and neurodegenerative disease

scientific article published on 12 February 2016
BRG1 chromatin remodeling activity is required for efficient chromatin binding by repressor element 1-silencing transcription factor (REST) and facilitates REST-mediated repression

scientific article published on 4 October 2006
Reactive oxygen species are second messengers of neurokinin signaling in peripheral sensory neurons

scientific article
Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer's disease

scientific article published on 12 August 2016
Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability

scientific article published on October 2010
Understanding inflammatory pain: ion channels contributing to acute and chronic nociception

scientific article published on 17 February 2010
Regulation of gene expression in the nervous system

scientific article published on September 2008
A quick, convenient and economical method for the reliable determination of methylglyoxal in millimolar concentrations: the N-acetyl-l-cysteine assay

scientific article published on 14 May 2012
The repressor element 1-silencing transcription factor regulates heart-specific gene expression using multiple chromatin-modifying complexes

scientific article published on 19 March 2007
Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells

scientific article published on 12 September 2013
The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype

scientific article published on September 2006
Induced pluripotent stem cells as tools for disease modelling and drug discovery in Alzheimer's disease

scientific article published on 13 June 2012
Triple cysteine module within M-type K+ channels mediates reciprocal channel modulation by nitric oxide and reactive oxygen species

scientific article published on April 2013
SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation

scientific article
Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research

scientific article
Redox and Nitric Oxide-Mediated Regulation of Sensory Neuron Ion Channel Function

scientific article published on April 15, 2014
Getting to NO Alzheimer’s Disease: Neuroprotection versus Neurotoxicity Mediated by Nitric Oxide

scientific article published on November 30, 2015
Neuroprotection of Neuro2a cells and the cytokine suppressive and anti-inflammatory mode of action of resveratrol in activated RAW264.7 macrophages and C8-B4 microglia

scientific article published on 29 October 2015
Chronic inflammation alters production and release of glutathione and related thiols in human U373 astroglial cells

scientific article
Impairments in Motor Neurons, Interneurons and Astrocytes Contribute to Hyperexcitability in ALS: Underlying Mechanisms and Paths to Therapy

scientific article published on 3 February 2017
Cytoprotective properties of traditional Chinese medicinal herbal extracts in hydrogen peroxide challenged human U373 astroglia cells

scientific article
Comparison of effects of anandamide at recombinant and endogenous rat vanilloid receptors

scientific article published in December 2002
Determination of anti-inflammatory activities of standardised preparations of plant- and mushroom-based foods

scientific article published on 8 May 2013
The heat shock response in neurons and astroglia and its role in neurodegenerative diseases.

scientific article published on 18 September 2017
Anti-inflammatory effects of five commercially available mushroom species determined in lipopolysaccharide and interferon-γ activated murine macrophages

scientific article published on 14 October 2013
Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease

scientific article published on 28 July 2016
Development of a high-performance liquid chromatography method for the simultaneous quantitation of glutathione and related thiols

scientific article
Astrocytic modulation of cortical oscillations

scientific article published on 01 August 2018
Evaluation of Skin Fibroblasts from Amyotrophic Lateral Sclerosis Patients for the Rapid Study of Pathological Features.

scientific article
A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer's Disease and Frontotemporal Dementia Disease Modeling

scientific article published on 02 September 2020
Viral-free generation and characterization of a human induced pluripotent stem cell line from dermal fibroblasts

Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing wild-type PSEN1

scientific article published on 13 August 2018
Neurodevelopmental Expression Profile of Dimeric and Monomeric Group 1 mGluRs: Relevance to Schizophrenia Pathogenesis and Treatment

scientific article published on 10 October 2016
Dynamic interplay between H-current and M-current controls motoneuron hyperexcitability in amyotrophic lateral sclerosis

scientific article published on 05 April 2019
Proenergetic effects of resveratrol in the murine neuronal cell line Neuro2a

scientific article published on 12 August 2013
Understanding the Role of ApoE Fragments in Alzheimer's Disease

scientific article published on 17 September 2018
The metastability of the proteome of spinal motor neurons underlies their selective vulnerability in ALS

scientific article published on 03 April 2019
The serine protease HtrA1 contributes to the formation of an extracellular 25-kDa apolipoprotein E fragment that stimulates neuritogenesis

scientific article published on 2 February 2018
Multiple chromatin modifications important for gene expression changes in cardiac hypertrophy

scientific article published in December 2006
Identification and High-Resolution Imaging of α-Tocopherol from Human Cells to Whole Animals by TOF-SIMS Tandem Mass Spectrometry

scientific article published on 12 June 2018
Electrochemical biosensing strategies for DNA methylation analysis.

scientific article published on 17 February 2017
Nitric Oxide: A Regulator of Cellular Function in Health and Disease

scientific article published on December 21, 2015
PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia

scientific article published on 12 September 2019
A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia

scientific article

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