List of works - Chaya Brodie

Alpha1-AMP-activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase C zeta

scientific article published on 20 April 2009

Altered adenosine-to-inosine RNA editing in human cancer

scientific article

An essential role of ERK signalling in TPA-induced reactivation of Kaposi's sarcoma-associated herpesvirus

scientific article

Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells

scientific article

Bone marrow stromal cell therapy reduces proNGF and p75 expression in mice with experimental autoimmune encephalomyelitis

scientific article published on 03 February 2009

Cilengitide induces autophagy-mediated cell death in glioma cells

scientific article

Cloning and characterization of human RTVP-1b, a novel splice variant of RTVP-1 in glioma cells

scientific article (publication date: 26 October 2007)

Design principles for noninvasive, longitudinal and quantitative cell tracking with nanoparticle-based CT imaging

scientific article published on 6 October 2016

Effect of helium/neon laser irradiation on nerve growth factor synthesis and secretion in skeletal muscle cultures

scientific article

FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-kappaB signaling pathway

scientific article

GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis

scientific article published on 10 April 2008

HSP27 mediates SPARC-induced changes in glioma morphology, migration, and invasion

scientific article

Inhibition of 5-lipoxygenase triggers apoptosis in prostate cancer cells via down-regulation of protein kinase C-epsilon

scientific article

Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival

scientific article

Insulin stimulation of PKCδ triggers its rapid degradation via the ubiquitin-proteasome pathway

scientific article published on 12 August 2010

Insulin-like growth factor binding protein 7 mediates glioma cell growth and migration

scientific article published on December 2008

Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal

scientific article published on February 2013

Mesenchymal stem cells enhance the oncolytic effect of Newcastle disease virus in glioma cells and glioma stem cells via the secretion of TRAIL.

scientific article published on 10 October 2016

MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor

scientific article

Multiple PKCdelta tyrosine residues are required for PKCdelta-dependent activation of involucrin expression--a key role of PKCdelta-Y311.

scientific article

P2Y6 nucleotide receptor activates PKC to protect 1321N1 astrocytoma cells against tumor necrosis factor-induced apoptosis ⬇️

scientific article

PIF* promotes brain re-myelination locally while regulating systemic inflammation- clinically relevant multiple sclerosis M.smegmatis model

scientific article

PKCdelta associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters

scientific article

Phosphorylation of protein kinase Cdelta on distinct tyrosine residues induces sustained activation of Erk1/2 via down-regulation of MKP-1: role in the apoptotic effect of etoposide

scientific article published on 23 April 2008

PreImplantation factor (PIF) therapy provides comprehensive protection against radiation induced pathologies

scientific article published on 16 July 2016

Preferential expression of functional IL-17R in glioma stem cells: potential role in self-renewal

scientific article published on 8 January 2016

Proteasome inhibitors sensitize glioma cells and glioma stem cells to TRAIL-induced apoptosis by PKCε-dependent downregulation of AKT and XIAP expressions

scientific article published on 29 March 2011

Protein kinase C-epsilon regulates the apoptosis and survival of glioma cells

scientific article published on August 2005

Protein kinase Cδ but not PKCα is involved in insulin-induced glucose metabolism in hepatocytes

scientific article published on June 2012

RTVP-1 expression is regulated by SRF downstream of protein kinase C and contributes to the effect of SRF on glioma cell migration

scientific article

RTVP-1 promotes mesenchymal transformation of glioma via a STAT-3/IL-6-dependent positive feedback loop

scientific article

RTVP-1 regulates glioma cell migration and invasion via interaction with N-WASP and hnRNPK.

scientific article

Radiation sensitization of glioblastoma by cilengitide has unanticipated schedule-dependency

scientific article

RasGRP3 regulates the migration of glioma cells via interaction with Arp3

scientific article

Related to testes-specific, vespid and pathogenesis protein-1 is regulated by methylation in glioblastoma

scientific article published on 27 January 2014

Related to testes-specific, vespid, and pathogenesis protein-1 (RTVP-1) is overexpressed in gliomas and regulates the growth, survival, and invasion of glioma cells

scientific article published on April 2006

Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma

scientific article (publication date: 30 August 2016)

Role of protein kinase C delta in reactivation of Kaposi's sarcoma-associated herpesvirus

scientific article

Roles of tyrosine phosphorylation and cleavage of protein kinase Cdelta in its protective effect against tumor necrosis factor-related apoptosis inducing ligand-induced apoptosis

scientific article

SPARC-induced increase in glioma matrix and decrease in vascularity are associated with reduced VEGF expression and secretion

scientific article

TRAIL conjugated to nanoparticles exhibits increased anti-tumor activities in glioma cells and glioma stem cells in vitro and in vivo

scientific article published on 8 November 2012

The localization of protein kinase Cdelta in different subcellular sites affects its proapoptotic and antiapoptotic functions and the activation of distinct downstream signaling pathways

scientific article

The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells

scientific article published on 7 March 2017

The phosphorylation of tyrosine 332 is necessary for the caspase 3-dependent cleavage of PKCdelta and the regulation of cell apoptosis

scientific article

The regulatory domain of protein kinase C delta positively regulates insulin receptor signaling

scientific journal article

Therapeutic Effect of Astroglia-like Mesenchymal Stem Cells Expressing Glutamate Transporter in a Genetic Rat Model of Depression

scientific article published on 6 July 2017

Tyrosine 311 is phosphorylated by c-Abl and promotes the apoptotic effect of PKCdelta in glioma cells

scientific article published on 16 November 2006

Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide

scientific article

List of works by Chaya Brodie

Alpha1-AMP-activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase C zeta

Altered adenosine-to-inosine RNA editing in human cancer

An essential role of ERK signalling in TPA-induced reactivation of Kaposi's sarcoma-associated herpesvirus

Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells

Bone marrow stromal cell therapy reduces proNGF and p75 expression in mice with experimental autoimmune encephalomyelitis

Cilengitide induces autophagy-mediated cell death in glioma cells

Cloning and characterization of human RTVP-1b, a novel splice variant of RTVP-1 in glioma cells

Design principles for noninvasive, longitudinal and quantitative cell tracking with nanoparticle-based CT imaging

Effect of helium/neon laser irradiation on nerve growth factor synthesis and secretion in skeletal muscle cultures

FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-kappaB signaling pathway

GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis

HSP27 mediates SPARC-induced changes in glioma morphology, migration, and invasion

Inhibition of 5-lipoxygenase triggers apoptosis in prostate cancer cells via down-regulation of protein kinase C-epsilon

Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival

Insulin stimulation of PKCδ triggers its rapid degradation via the ubiquitin-proteasome pathway

Insulin-like growth factor binding protein 7 mediates glioma cell growth and migration

Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal

Mesenchymal stem cells enhance the oncolytic effect of Newcastle disease virus in glioma cells and glioma stem cells via the secretion of TRAIL.

MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor

Multiple PKCdelta tyrosine residues are required for PKCdelta-dependent activation of involucrin expression--a key role of PKCdelta-Y311.

P2Y6 nucleotide receptor activates PKC to protect 1321N1 astrocytoma cells against tumor necrosis factor-induced apoptosis ⬇️

PIF* promotes brain re-myelination locally while regulating systemic inflammation- clinically relevant multiple sclerosis M.smegmatis model

PKCdelta associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters

Phosphorylation of protein kinase Cdelta on distinct tyrosine residues induces sustained activation of Erk1/2 via down-regulation of MKP-1: role in the apoptotic effect of etoposide

PreImplantation factor (PIF) therapy provides comprehensive protection against radiation induced pathologies

Preferential expression of functional IL-17R in glioma stem cells: potential role in self-renewal

Proteasome inhibitors sensitize glioma cells and glioma stem cells to TRAIL-induced apoptosis by PKCε-dependent downregulation of AKT and XIAP expressions

Protein kinase C-epsilon regulates the apoptosis and survival of glioma cells

Protein kinase Cδ but not PKCα is involved in insulin-induced glucose metabolism in hepatocytes

RTVP-1 expression is regulated by SRF downstream of protein kinase C and contributes to the effect of SRF on glioma cell migration

RTVP-1 promotes mesenchymal transformation of glioma via a STAT-3/IL-6-dependent positive feedback loop

RTVP-1 regulates glioma cell migration and invasion via interaction with N-WASP and hnRNPK.

Radiation sensitization of glioblastoma by cilengitide has unanticipated schedule-dependency

RasGRP3 regulates the migration of glioma cells via interaction with Arp3

Related to testes-specific, vespid and pathogenesis protein-1 is regulated by methylation in glioblastoma

Related to testes-specific, vespid, and pathogenesis protein-1 (RTVP-1) is overexpressed in gliomas and regulates the growth, survival, and invasion of glioma cells

Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma

Role of protein kinase C delta in reactivation of Kaposi's sarcoma-associated herpesvirus

Roles of tyrosine phosphorylation and cleavage of protein kinase Cdelta in its protective effect against tumor necrosis factor-related apoptosis inducing ligand-induced apoptosis

SPARC-induced increase in glioma matrix and decrease in vascularity are associated with reduced VEGF expression and secretion

TRAIL conjugated to nanoparticles exhibits increased anti-tumor activities in glioma cells and glioma stem cells in vitro and in vivo

The localization of protein kinase Cdelta in different subcellular sites affects its proapoptotic and antiapoptotic functions and the activation of distinct downstream signaling pathways

The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells

The phosphorylation of tyrosine 332 is necessary for the caspase 3-dependent cleavage of PKCdelta and the regulation of cell apoptosis

The regulatory domain of protein kinase C delta positively regulates insulin receptor signaling

Therapeutic Effect of Astroglia-like Mesenchymal Stem Cells Expressing Glutamate Transporter in a Genetic Rat Model of Depression

Tyrosine 311 is phosphorylated by c-Abl and promotes the apoptotic effect of PKCdelta in glioma cells

Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide