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List of works by Hubert Hřebabecký

1-(3,5-O-Alkylidene-2-deoxy-4-C-hydroxymethyl-α-L-threo-pentofuranosyl)uracils

2',3'-Dideoxy- and 3'-Azido-2',3'-dideoxynucleosides of 5-Phenyl-2(1H)-pyrimidinone. Preparation of 2',3'-Dideoxypentofuranoses

5′-Halogeno-2′,3′-cyclic sulphite isomers in the preparation of 5′-halogeno nucleosides. Synthesis of 5′-deoxyuridine and 5′-deoxy-5-fluorouridine

scientific article published on March 1, 1978

9-Norbornyl-6-chloropurine (NCP) induces cell death through GSH depletion-associated ER stress and mitochondrial dysfunction

scientific article published on 7 June 2016

A New Analogue of Locked Cyclohexane Nucleic Acids

Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymerase

scientific article (publication date: November 2016)

Conformationally locked nucleoside analogues based on the bridgehead substituted 7-oxonorbornane and their antiviral properties

Control of α/β Anomer Formation by a 2',5' Bridge: Toward Nucleoside Derivatives Locked in the South Conformation.

scientific article published on 3 October 2017

From norbornane-based nucleotide analogs locked in South conformation to novel inhibitors of feline herpes virus

scientific article published on 13 April 2014

Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action

scientific article

Microwave-Assisted Solvent-Free Diels-Alder Reaction - A Fast and Simple Route to Various 5,6-Substituted Norbornenes and Polychlorinated Norbornenes

Model synthesis of six-membered carbocyclic spironucleosides

New carbocyclic nucleoside analogues built on a bicyclo[2.2.2]octane-2,2-dimethanol template

article published in 2009

Norbornane as the novel pseudoglycone moiety in nucleosides

Norbornane-based nucleoside and nucleotide analogues locked in North conformation

scientific article published on 15 November 2014

Novel substituted 9-norbornylpurines and their activities against RNA viruses

scientific article published in 2012

Nucleoside inhibitors of tick-borne encephalitis virus

scientific article

One-pot build-up procedure for the synthesis of variously substituted purine derivatives

article

Preparation of 5-Benzyluracil and 5-Benzylcytosine Nucleosides as Potential Inhibitors of Uridine Phosphorylase

Preparation of Chloro and Sulfanyl Derivatives of 1-(2-Deoxy-4-C-hydroxymethyl-α-L-threo-Pentofuranosyl)uracil

Preparation of Thymidine-4'-C-carboxylic Acid and Its Derivatives

Purine analogs as phosphatidylinositol 4-kinase IIIβ inhibitors

scientific article

Quantum chemical calculation of the (S)-9-(2,3-dihydroxypropyl)adenine molecule.

scientific article

Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology

scientific article published on 22 December 2016

SAR studies of 9-norbornylpurines as Coxsackievirus B3 inhibitors

scientific article

Synthesis and biological evaluation of conformationally restricted adenine bicycloribonucleosides

scientific article published on 4 August 2015

Synthesis of 1-(3-azido-2,3-dideoxy-β- d -allofuranosyl)thymine, 1-(2,3-dideoxy-β- d -allofuranosyl)thymine, and 1-(2,3-dideoxy-β- d - erythro -hex-2-enofuranosyl)thymine

scientific article published on September 2, 1991

Synthesis of 5-Phenyl-2(1H)-pyrimidinone Nucleosides

Synthesis of 5-Phenylcytosine Nucleoside Derivatives

Synthesis of 5-methyl-6-azacytidine

Synthesis of Carba Analogues of 2'-Deoxy-4'-C-(hydroxymethyl)nucleosides

Synthesis of Carba Analogues of Deoxy-4-C-(hydroxymethyl)hexopyranoses, Intermediates in the Synthesis of Carbocyclic Nucleosides

Synthesis of Carba Analogues of Deoxy-4-C-(hydroxymethyl)pentofuranoses, Intermediates in the Synthesis of Carbocyclic Nucleosides

Synthesis of Carbocyclic 4'-C-Hydroxymethyl Analogues of Azidodeoxythymidine, Deoxythymidine, Deoxydidehydrothymidine and Thymidine Carba Analogue with Fused Oxetane Ring

Synthesis of Novel Carbocyclic Nucleoside Analogues Containing Bicyclo[2.2.1]hept-2-ene-2-methanol

Synthesis of Novel Carbocyclic Nucleoside Analogues Derived from 2-(Hydroxymethyl)bicyclo[2.2.1]heptane

Synthesis of Novel Carbocyclic Nucleosides and Pro-Tides Derived from 4-Oxatricyclo[4.2.1.03,7]nonane-9-methanol

Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 3-(Hydroxymethyl)bicyclo[2.2.1]heptane-2,5-diol

Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 5,5- and 6,6-Bis(hydroxymethyl)bicyclo[2.2.1]heptan-2-ol

Synthesis of Novel Racemic Conformationally Locked Carbocyclic Nucleosides Derived from 7-Substituted Bicyclo[2.2.1]hept-5-ene-2,2-dimethanols

Synthesis of Purine Nucleoside Analogues Derived from Carbocyclic 5-C-(Hydroxymethyl)hexopyranoses

article published in 2004

Synthesis of Racemic 2-Hydroxy-4- and 2-Hydroxy-5-(hydroxymethyl)cyclohexane Nucleoside Analogues

Synthesis of Racemic 2-Hydroxy-4- and 2-Hydroxy-5-(hydroxymethyl)cyclohexane Pyrimidine C-Nucleoside Analogues

Synthesis of Racemic 9-(6- and 2,6-Substituted 9H-Purin-9-yl)-5-oxatricyclo[4.2.1.03,7]nonane-3-methanols, Novel Conformationally Locked Carbocyclic Nucleosides

Synthesis of locked cyclohexene and cyclohexane nucleic acids (LCeNA and LCNA) with modified adenosine units

scientific article published on 01 March 2015

Synthesis of novel azanorbornylpurine derivatives

Synthesis of novel carbocyclic nucleoside analogues derived from 7-oxabicyclo[2.2.1]heptane-2-methanol

Synthesis of novel purine-based coxsackievirus inhibitors bearing polycylic substituents at the N-9 position

scientific article

Synthesis of novel racemic carbocyclic nucleoside analogues derived from 4,8-dioxatricyclo[4.2.1.03,7]nonane-9-methanol and 4-oxatricyclo[4.3.1.03,7]decane-10-methanol, compounds with activity against Coxsackie viruses

Synthesis of novel thienonorbornylpurine derivatives

Synthesis of the sulfonamido derivatives of arabinonucleosides

The determination of sulfoxide configuration in five-membered rings using NMR spectroscopy and DFT calculations

The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design

scientific article

Transport mechanisms of a novel antileukemic and antiviral compound 9-norbornyl-6-chloropurine

scientific article published on 31 March 2014