List of works by Adam T Whaley-Connell

A decade after the KDOQI CKD guidelines: impact on the National Kidney Foundation's Kidney Early Evaluation Program (KEEP)

scientific article published on 01 November 2012

Adaptive mechanisms to compensate for overnutrition-induced cardiovascular abnormalities

scientific article published on 3 August 2011

Albumin activation of NAD(P)H oxidase activity is mediated via Rac1 in proximal tubule cells

scientific article published on 5 January 2007

Aldosterone and Risk for Insulin Resistance.

scientific article published on 7 November 2011

Aldosterone and hypertension in the cardiometabolic syndrome

scientific article published in February 2008

Angiotensin II-mediated oxidative stress promotes myocardial tissue remodeling in the transgenic (mRen2) 27 Ren2 rat

scientific article published on 17 April 2007

Angiotensin type 1 receptor resistance to blockade in the opossum proximal tubule cell due to variations in the binding pocket.

scientific article published on 6 February 2013

Awareness of kidney disease and relationship to end-stage renal disease and mortality.

scientific article

BP Targets in Older Adults with CKD: Additional Evidence, but Uncertainty Continues

scientific article published on 14 August 2015

BP and Renal Outcomes in Diabetic Kidney Disease: The Veterans Affairs Nephropathy in Diabetes Trial.

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Basic science: Pathophysiology: the cardiorenal metabolic syndrome

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Blood Pressure-Related Outcomes in a Diabetic Population.

scientific article published on 23 May 2016

CKD and cardiovascular disease in screened high-risk volunteer and general populations: the Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004.

scientific article published in April 2008

CKD awareness in the United States: the Kidney Early Evaluation Program (KEEP).

scientific article published in August 2008

CKD in the United States: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004.

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Cardiometabolic syndrome and chronic kidney disease: what is the link?

scientific article published on January 2006

Cardiovascular disease in chronic kidney disease: data from the Kidney Early Evaluation Program (KEEP).

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Cardiovascular risk modification in participants with coronary disease screened by the Kidney Early Evaluation Program.

scientific article published in December 2010

Central Pressure and Biomarker Responses to Renin Inhibition with Hydrochlorothiazide and Ramipril in Obese Hypertensives: The ATTAIN Study

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Chronic kidney disease and the cardiometabolic syndrome

scientific article published on 01 August 2006

Chronic kidney disease, prevalence of premature cardiovascular disease, and relationship to short-term mortality.

scientific article published on 4 June 2008

Combination of direct renin inhibition with angiotensin type 1 receptor blockade improves aldosterone but does not improve kidney injury in the transgenic Ren2 rat.

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Comparison of CKD awareness in a screening population using the Modification of Diet in Renal Disease (MDRD) study and CKD Epidemiology Collaboration (CKD-EPI) equations.

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Comparison of the CKD Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) study equations: risk factors for and complications of CKD and mortality in the Kidney Early Evaluation Program (KEEP).

scientific article published in March 2011

Cytokine abnormalities in the etiology of the cardiometabolic syndrome

scientific article published in April 2010

DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat

scientific article

Diabetes mellitus and CKD awareness: the Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES).

scientific article published in April 2009

Diabetes mellitus in CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition and Examination Survey (NHANES) 1999-2004.

scientific article published in April 2008

Diabetes: Aspirin and prevention of diabetes still a topic of debate.

scientific article published in July 2009

Diabetic kidney disease: a report from an ADA Consensus Conference

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Diabetic kidney disease: a report from an ADA Consensus Conference.

scientific article published on October 2014

Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy.

scientific article published on 13 February 2009

Dipeptidylpeptidase inhibition is associated with improvement in blood pressure and diastolic function in insulin-resistant male Zucker obese rats

scientific article published on 07 May 2013

Direct renin inhibition improves systemic insulin resistance and skeletal muscle glucose transport in a transgenic rodent model of tissue renin overexpression.

scientific article published on 26 February 2009

Dysglycemia predicts cardiovascular and kidney disease in the Kidney Early Evaluation Program

scientific article published in January 2010

Educational programs improve the preparation for dialysis and survival of patients with chronic kidney disease

scientific article

Effect of ethnicity on the progression of diabetic kidney disease independent of glycemic control.

scientific article published on 4 June 2009

Effect of renin inhibition and AT1R blockade on myocardial remodeling in the transgenic Ren2 rat

scientific article published on 6 May 2008

Endothelial Mineralocorticoid Receptor Deletion Prevents Diet-Induced Cardiac Diastolic Dysfunction in Females

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Fructose and uric acid: is there a role in endothelial function?

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Gestational diabetes mellitus alone in the absence of subsequent diabetes is associated with microalbuminuria: results from the Kidney Early Evaluation Program (KEEP).

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Hypertension Management in Diabetic Kidney Disease

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Hypertension and insulin resistance

scientific article published on 27 July 2009

Hypertension in the high-cardiovascular-risk populations

scientific article published on January 2011

Hypertension management in type 2 diabetes mellitus: recommendations of the Joint National Committee VII.

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Hyponatremia, arginine vasopressin dysregulation, and vasopressin receptor antagonism.

scientific article published on 14 December 2006

Implications for glucose measures in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study.

scientific article published on January 2014

Indices of obesity and cardiometabolic risk

scientific article published on 24 October 2011

Inhibition of nitric oxide synthase evokes central sympatho-excitation in healthy humans

scientific article published in September 2009

Initial choice of antihypertensive on long-term cardiovascular outcomes in CKD.

scientific article published on 17 May 2012

Insulin resistance, oxidative stress, and podocyte injury: role of rosuvastatin modulation of filtration barrier injury.

scientific article published on 3 October 2007

Is it time to target prehypertension

scientific article published on 01 December 2010

Liquid meal composition, postprandial satiety hormones, and perceived appetite and satiety in obese women during acute caloric restriction.

scientific article published on 15 March 2013

Low aerobic capacity and high-fat diet contribute to oxidative stress and IRS-1 degradation in the kidney.

scientific article published on 20 February 2009

Low birth weight is associated with chronic kidney disease only in men.

scientific article published on 19 December 2007

Low-Dose Mineralocorticoid Receptor Blockade Prevents Western Diet-Induced Arterial Stiffening in Female Mice

scientific article published on 26 May 2015

Metabolic Control of Blood Pressure Variability in Humans

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Metabolic impact of adding a thiazide diuretic to captopril

scientific article published on 19 February 2013

Micro vs. macrovascular reactivity in insulin resistance: the debate reignited

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Mineralocorticoid and apparent mineralocorticoid syndromes of secondary hypertension.

scientific article published on May 2015

Mineralocorticoid receptor antagonism attenuates vascular apoptosis and injury via rescuing protein kinase B activation

scientific article published on 29 December 2008

Mineralocorticoid receptor blockade attenuates chronic overexpression of the renin-angiotensin-aldosterone system stimulation of reduced nicotinamide adenine dinucleotide phosphate oxidase and cardiac remodeling.

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Mineralocorticoid receptor blockade improves diastolic function independent of blood pressure reduction in a transgenic model of RAAS overexpression.

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Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease.

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NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat

scientific article published on 28 May 2007

National Kidney Foundation's Kidney Early Evaluation Program (KEEP) annual data report 2010: executive summary.

scientific article published in March 2011

National Kidney Foundation's Kidney Early Evaluation Program (KEEP) annual data report 2011: executive summary

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Nebivolol attenuates redox-sensitive glomerular and tubular mediated proteinuria in obese rats

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Nebivolol improves diastolic dysfunction and myocardial remodeling through reductions in oxidative stress in the Zucker obese rat.

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Nebivolol improves insulin sensitivity in the TGR(Ren2)27 rat.

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Nebivolol in obese and non-obese hypertensive patients.

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Nebivolol reduces proteinuria and renal NADPH oxidase-generated reactive oxygen species in the transgenic Ren2 rat.

scientific article published on 17 July 2009

No independent association of serum phosphorus with risk for death or progression to end-stage renal disease in a large screen for chronic kidney disease

scientific article

Novel interventions for resistant hypertension

scientific article published on 01 September 2013

Novel therapeutics in hypertension and kidney disease.

scientific article published in September 2015

Obesity and heart failure as a mediator of the cerebrorenal interaction

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Obesity and insulin resistance in resistant hypertension: implications for the kidney

scientific article published on May 2015

Obesity is associated with increased parathyroid hormone levels independent of glomerular filtration rate in chronic kidney disease

scientific article published on 02 October 2009

Obesity, insulin resistance, and nocturnal systolic blood pressure

scientific article published on 22 January 2008

Obesity-related alterations in cardiac lipid profile and nondipping blood pressure pattern during transition to diastolic dysfunction in male db/db mice

scientific article

Outcomes of carotid revascularization in patients with chronic kidney disease.

scientific article published on October 2008

Over-nutrition contributes to tubulointerstitial fibrosis by targeting nutrient-sensing kinases: role for the mTOR/S6K pathway

scientific article published on March 2012

Overnutrition and the Cardiorenal Syndrome: Use of a Rodent Model to Examine Mechanisms.

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Oxidative stress and glomerular filtration barrier injury: role of the renin-angiotensin system in the Ren2 transgenic rat

scientific article published on 20 June 2006

Oxidative stress contributes to pulmonary hypertension in the transgenic (mRen2)27 rat.

scientific article published on 18 April 2008

Prevalence and associations of anemia of CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004.

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Prevalence of CKD and comorbid illness in elderly patients in the United States: results from the Kidney Early Evaluation Program (KEEP).

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Prevention of obesity-induced renal injury in male mice by DPP4 inhibition

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Proximal tubule microvilli remodeling and albuminuria in the Ren2 transgenic rat

scientific article published on 10 October 2006

Racial differences in kidney function among individuals with obesity and metabolic syndrome: results from the Kidney Early Evaluation Program (KEEP).

scientific article published in March 2010

Redox control of renal function and hypertension.

scientific article published on December 2008

Renal redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and diabetic nephropathy: paying homage to the podocyte.

scientific article

Renin inhibition and AT(1)R blockade improve metabolic signaling, oxidant stress and myocardial tissue remodeling.

scientific article published on 24 January 2013

Renin inhibition attenuates insulin resistance, oxidative stress, and pancreatic remodeling in the transgenic Ren2 rat.

scientific article published on 24 July 2008

Renin-angiotensin-aldosterone system and oxidative stress in cardiovascular insulin resistance.

scientific article published on 22 June 2007

Renin-angiotensin-aldosterone system intervention in the cardiometabolic syndrome and cardio-renal protection.

scientific article published on October 2007

Resistant hypertension in the high-risk metabolic patient

scientific article published on February 2011

Risk factors for ESRD in individuals with preserved estimated GFR with and without albuminuria: results from the Kidney Early Evaluation Program (KEEP)

scientific article

Rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, decreases cardiac oxidative stress and remodeling in Ren2 transgenic rats.

scientific article published on 22 February 2007

Salt Loading Promotes Kidney Injury via Fibrosis in Young Female Ren2 Rats.

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Salt loading exacerbates diastolic dysfunction and cardiac remodeling in young female Ren2 rats.

scientific article published on 24 September 2013

Secondary hypertension: beginnings and transitions

scientific article published in May 2015

Sex differences in baroreflex sensitivity, heart rate variability, and end organ damage in the TGR(mRen2)27 rat.

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The Association between Parathyroid Hormone Levels and Hemoglobin in Diabetic and Nondiabetic Participants in the National Kidney Foundation's Kidney Early Evaluation Program.

scientific article published on June 2013

The Role of Overweight and Obesity in the Cardiorenal Syndrome

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The association of parathyroid hormone with ESRD and pre-ESRD mortality in the Kidney Early Evaluation Program

scientific article published on 12 October 2012

The effects of resistance training on metabolic health with weight regain

scientific article published in January 2010

The emerging role of biomarkers in diabetic and hypertensive chronic kidney disease.

scientific article published on February 2010

The kaliuretic impact of cicletanine compared to hydrochlorothiazide

scientific article published on 01 April 2012

The role of oxidative stress in the metabolic syndrome.

scientific article published on January 2011

The use and interpretation of troponin in ESRD patients

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Therapy for the altered mineral metabolism of chronic kidney disease: implications for vascular calcification.

scientific article published on December 2007

To RAS or not to RAS? The evidence for and cautions with renin-angiotensin system inhibition in patients with diabetic kidney disease.

scientific article published on 09 April 2013

Tonsillectomy for the treatment of tonsillitis-induced immunoglobulin A nephropathy

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Trends in mineral metabolism: Kidney Early Evaluation Program (KEEP) and the National Health and Nutrition Examination Survey (NHANES) 1999-2004

scientific article published on 01 April 2008

Two-dimensional zymography differentiates gelatinase isoforms in stimulated microglial cells and in brain tissues of acute brain injuries

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Uric acid promotes left ventricular diastolic dysfunction in mice fed a Western diet.

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Weight-loss-associated changes in bone mineral density and bone turnover after partial weight regain with or without aerobic exercise in obese women.

scientific article published on 21 December 2011