List of works - Hervé Galons

A yeast-based assay to isolate drugs active against mammalian prions

scientific article published on May 2006

Aftins increase amyloid-β42, lower amyloid-β38, and do not alter amyloid-β40 extracellular production in vitro: toward a chemical model of Alzheimer's disease?

scientific article

Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions

scientific article

Antiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophy

scientific article

Antiprion drugs as chemical tools to uncover mechanisms of prion propagation

scientific article published on 20 January 2007

Antitumoral effects of cyclin-dependent kinases inhibitors CR8 and MR4 on chronic myeloid leukemia cell lines

scientific article published on 17 July 2015

CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells

scientific article

CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD.

scientific article published on 3 October 2012

Cyclin-dependent kinase inhibitors closer to market launch?

scientific article published on 22 April 2013

Cyclin-dependent kinase inhibitors: a survey of recent patent literature

scientific article published on March 2010

Design of cocaethylene and cocaine conjugates to produce highly selective polyclonal antibodies

scientific article published on February 2006

Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor

scientific article published on 22 September 2016

FAF-Drugs2: free ADME/tox filtering tool to assist drug discovery and chemical biology projects

scientific article

Investigation of N-hydroxythalidomide in vitro stability and comparison to other N-substituted derivatives

scientific article

Mode of action of the antiprion drugs 6AP and GA on ribosome assisted protein folding

scientific article

Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis

scientific article published on 18 March 2016

Potent inhibitors of CDK5 derived from roscovitine: synthesis, biological evaluation and molecular modelling

scientific article published on 10 November 2012

Preliminary biological evaluations of new thalidomide analogues for multiple sclerosis application

scientific article

Procedure for identification and characterization of drugs efficient against mammalian prion: from a yeast-based antiprion drug screening assay to in vivo mouse models

scientific article

Protein folding activity of ribosomal RNA is a selective target of two unrelated antiprion drugs

scientific article

Roscovitine targets, protein kinases and pyridoxal kinase

scientific journal article

Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.

scientific article

Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action

scientific article

Specific Triazine Herbicides Induce Amyloid-β42 Production

scientific article

The FAF-Drugs2 server: a multistep engine to prepare electronic chemical compound collections

scientific article

The antiprion compound 6-aminophenanthridine inhibits the protein folding activity of the ribosome by direct competition

scientific article published on 14 May 2013

The toll-like receptor agonist imiquimod is active against prions

scientific article (publication date: 2013)

Use of ATP analogs to inhibit HIV-1 transcription

scientific article

List of works by Hervé Galons

A yeast-based assay to isolate drugs active against mammalian prions

Aftins increase amyloid-β42, lower amyloid-β38, and do not alter amyloid-β40 extracellular production in vitro: toward a chemical model of Alzheimer's disease?

Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions

Antiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophy

Antiprion drugs as chemical tools to uncover mechanisms of prion propagation

Antitumoral effects of cyclin-dependent kinases inhibitors CR8 and MR4 on chronic myeloid leukemia cell lines

CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells

CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD.

Cyclin-dependent kinase inhibitors closer to market launch?

Cyclin-dependent kinase inhibitors: a survey of recent patent literature

Design of cocaethylene and cocaine conjugates to produce highly selective polyclonal antibodies

Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor

FAF-Drugs2: free ADME/tox filtering tool to assist drug discovery and chemical biology projects

Investigation of N-hydroxythalidomide in vitro stability and comparison to other N-substituted derivatives

Mode of action of the antiprion drugs 6AP and GA on ribosome assisted protein folding

Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis

Potent inhibitors of CDK5 derived from roscovitine: synthesis, biological evaluation and molecular modelling

Preliminary biological evaluations of new thalidomide analogues for multiple sclerosis application

Procedure for identification and characterization of drugs efficient against mammalian prion: from a yeast-based antiprion drug screening assay to in vivo mouse models

Protein folding activity of ribosomal RNA is a selective target of two unrelated antiprion drugs

Roscovitine targets, protein kinases and pyridoxal kinase

Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.

Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action

Specific Triazine Herbicides Induce Amyloid-β42 Production

The FAF-Drugs2 server: a multistep engine to prepare electronic chemical compound collections

The antiprion compound 6-aminophenanthridine inhibits the protein folding activity of the ribosome by direct competition

The toll-like receptor agonist imiquimod is active against prions

Use of ATP analogs to inhibit HIV-1 transcription