List of works - Thomas E. Mahan

Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.

scientific article published in December 2017

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.

scientific article

Altered sleep and EEG power in the P301S Tau transgenic mouse model

scientific article published on 15 February 2017

Analysis of in vivo turnover of tau in a mouse model of tauopathy

scientific article published on 26 October 2015

Anti-ApoE antibody given after plaque onset decreases Aβ accumulation and improves brain function in a mouse model of Aβ amyloidosis

scientific article

Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.

scientific article published on 26 September 2013

Anti-tau antibody reduces insoluble tau and decreases brain atrophy

scientific article published on 23 January 2015

ApoE facilitates the microglial response to amyloid plaque pathology.

scientific article published on 26 February 2018

Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model

scientific article published on 19 March 2015

Effects of growth hormone-releasing hormone on sleep and brain interstitial fluid amyloid-β in an APP transgenic mouse model

scientific article

High-affinity interactions and signal transduction between Aβ oligomers and TREM2

scientific article published on 01 November 2018

Hyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivo

scientific article published on 4 May 2015

In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis

scientific article published on 19 April 2013

Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model

scientific article published on 17 October 2019

Neuronal activity regulates extracellular tau in vivo

scientific article published on 17 February 2014

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

scientific article

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer’s disease.

scientific article published in January 2015

Proteopathic tau seeding predicts tauopathy in vivo.

scientific article

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

scientific article published on 18 April 2016

The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans

scientific article

List of works by Thomas E. Mahan

Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.

Altered sleep and EEG power in the P301S Tau transgenic mouse model

Analysis of in vivo turnover of tau in a mouse model of tauopathy

Anti-ApoE antibody given after plaque onset decreases Aβ accumulation and improves brain function in a mouse model of Aβ amyloidosis

Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.

Anti-tau antibody reduces insoluble tau and decreases brain atrophy

ApoE facilitates the microglial response to amyloid plaque pathology.

Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model

Effects of growth hormone-releasing hormone on sleep and brain interstitial fluid amyloid-β in an APP transgenic mouse model

High-affinity interactions and signal transduction between Aβ oligomers and TREM2

Hyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivo

In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis

Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model

Neuronal activity regulates extracellular tau in vivo

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer’s disease.

Proteopathic tau seeding predicts tauopathy in vivo.

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans