Search filters

List of works by Robert E Burke

A critical evaluation of the Braak staging scheme for Parkinson's disease.

scientific article published on November 2008

AAV transduction of dopamine neurons with constitutively active Rheb protects from neurodegeneration and mediates axon regrowth.

scientific article published on 18 October 2011

Age and α-synuclein expression interact to reveal a dependence of dopaminergic axons on endogenous Akt/PKB signaling.

scientific article

Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy

scientific article published on February 2011

An early axonopathy in a hLRRK2(R1441G) transgenic model of Parkinson disease.

scientific article published on 17 July 2015

Anatomical basis of glial cell line-derived neurotrophic factor expression in the striatum and related basal ganglia during postnatal development of the rat.

scientific article

Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo.

scientific article

Axon degeneration in Parkinson's disease

scientific article published on 18 January 2012

CEP11004, a novel inhibitor of the mixed lineage kinases, suppresses apoptotic death in dopamine neurons of the substantia nigra induced by 6-hydroxydopamine.

scientific article published in January 2004

CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism

scientific journal article

Clinical progression in Parkinson disease and the neurobiology of axons.

scientific article

Disease Modification for Parkinson's Disease: Axonal Regeneration and Trophic Factors

scientific article published on 30 March 2018

Distinct nuclear and cytoplasmic localization of caspase cleavage products in two models of induced apoptotic death in dopamine neurons of the substantia nigra

scientific article

Dopaminergic pathway reconstruction by Akt/Rheb-induced axon regeneration

scientific article published on 17 March 2011

Ectopic expression of cell cycle markers in models of induced programmed cell death in dopamine neurons of the rat substantia nigra pars compacta

scientific article

Expressing Constitutively Active Rheb in Adult Neurons after a Complete Spinal Cord Injury Enhances Axonal Regeneration beyond a Chondroitinase-Treated Glial Scar.

scientific article published in August 2015

Glial cell line-derived neurotrophic factor receptor GFRalpha1 is expressed in the rat striatum during postnatal development

scientific article published on August 2004

Glial cell line-derived neurotrophic factor receptor-α1 expressed in striatum in trans regulates development and injury response of dopamine neurons of the substantia nigra.

scientific article published on 19 January 2011

Induction of GDNF and BDNF by hRheb(S16H) transduction of SNpc neurons: neuroprotective mechanisms of hRheb(S16H) in a model of Parkinson's disease.

scientific article

Induction of axon growth in the adult brain: A new approach to restoration in Parkinson's disease

scientific article published on 4 December 2017

Intracellular signalling pathways in dopamine cell death and axonal degeneration.

scientific article

Lack of alpha-synuclein does not alter apoptosis of neonatal catecholaminergic neurons.

scientific article published on October 2004

Medial forebrain bundle axotomy during development induces apoptosis in dopamine neurons of the substantia nigra and activation of caspases in their degenerating axons

scientific article published in October 2002

Mixed lineage kinase-c-jun N-terminal kinase signaling pathway: a new therapeutic target in Parkinson's disease.

scientific article

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

scholarly article

Ontogenic cell death in the nigrostriatal system.

scientific article published on 3 September 2004

Patterns of developmental mRNA expression of neurturin and GFRalpha2 in the rat striatum and substantia nigra do not suggest a role in the regulation of natural cell death in dopamine neurons.

scientific article published on January 2004

Pitx3 is required for development of substantia nigra dopaminergic neurons.

scholarly article

Programmed cell death and new discoveries in the genetics of parkinsonism.

scientific article

Quantitative morphological comparison of axon-targeting strategies for gene therapies directed to the nigro-striatal projection

scientific article published on 5 December 2013

Regulation of presynaptic neurotransmission by macroautophagy

scientific article published in April 2012

Regulation of the development of mesencephalic dopaminergic systems by the selective expression of glial cell line-derived neurotrophic factor in their targets.

scientific article published on March 2004

Rheb GTPase regulates β-secretase levels and amyloid β generation

scientific article published on 24 December 2013

Paulina is supported by:

About Paulina

Help