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List of works by Timothy D. McHugh

A method for the detection of antibiotic resistance markers in clinical strains of Escherichia coli using MALDI mass spectrometry

scientific article published on 26 January 2015

A practical guide to measuring mutation rates in antibiotic resistance

scientific article

Advances in tuberculosis diagnostics: the Xpert MTB/RIF assay and future prospects for a point-of-care test

scientific article published on 24 March 2013

An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis

scientific article published on 10 November 2011

Analogues of Disulfides from Allium stipitatum Demonstrate Potent Anti-tubercular Activities through Drug Efflux Pump and Biofilm Inhibition.

scientific article published on 18 January 2018

Analysis of rpoB and pncA mutations in the published literature: an insight into the role of oxidative stress in Mycobacterium tuberculosis evolution?

scientific article

Antibacterial activity of head-to-head bis-benzimidazoles

scientific article published on 6 July 2013

Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay

scientific article

Application of SSCP to Identification of Resistance Mutations

scientific article published on 01 January 2001

Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment

scientific article published on July 2013

Assessment of treatment response by colony forming units, time to culture positivity and the molecular bacterial load assay compared in a mouse tuberculosis model

scientific article published on 8 May 2017

Biomarkers of treatment response in clinical trials of novel antituberculosis agents

scientific article published on July 2007

Blood and sputum eosinophils in COPD; relationship with bacterial load.

scientific article

Cautionary note on contamination of reagents used for molecular detection of SARS-CoV-2

scientific article published on 07 September 2020

Changes in prevalence and load of airway bacteria using quantitative PCR in stable and exacerbated COPD.

scientific article published on 3 August 2012

DNA sequence-selective C8-linked pyrrolobenzodiazepine-heterocyclic polyamide conjugates show anti-tubercular-specific activities.

scientific article

Detection and identification of bacteria in clinical samples by 16S rRNA gene sequencing: comparison of two different approaches in clinical practice

scientific article published on 8 December 2011

Direct detection of heteroresistance in Mycobacterium tuberculosis using molecular techniques

scientific article

Drug-resistant tuberculosis--current dilemmas, unanswered questions, challenges, and priority needs

scientific article published on 3 April 2012

Drug-resistant tuberculosis: time for visionary political leadership

scientific article

Early bactericidal activity of a moxifloxacin and isoniazid combination in smear-positive pulmonary tuberculosis

scientific article

Effect of subinhibitory concentrations of ciprofloxacin on Mycobacterium fortuitum mutation rates

scientific article published on 14 June 2005

Effectiveness of peer educators on the uptake of mobile X-ray tuberculosis screening at homeless hostels: a cluster randomised controlled trial

scientific article

Effects of different antibiotic classes on airway bacteria in stable COPD using culture and molecular techniques: a randomised controlled trial

scientific article

Enhanced heterogeneity of rpoB in Mycobacterium tuberculosis found at low pH.

scientific article published on 15 April 2009

Ertapenem and Faropenem against Mycobacterium tuberculosis: in vitro testing and comparison by macro and microdilution

scientific article published on 31 August 2020

Evaluation of a short, on-plate formic acid extraction method for matrix-assisted laser desorption ionization-time of flight mass spectrometry-based identification of clinically relevant yeast isolates

scientific article published on 29 January 2014

Evolutionary relationships among strains of Mycobacterium tuberculosis with few copies of IS6110.

scientific article published in April 2003

Fluoroquinolones and isoniazid-resistant tuberculosis: implications for the 2018 WHO guidance

scientific article published on 10 October 2019

Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis

scientific article

Genetic variation in Mycobacterium tuberculosis isolates from a London outbreak associated with isoniazid resistance

scientific article

Genomic Investigations unmask Mycoplasma amphoriforme, a new respiratory pathogen

scientific article

High-dose rifapentine with moxifloxacin for pulmonary tuberculosis

scientific article

Identification of 2-aminothiazole-4-carboxylate derivatives active against Mycobacterium tuberculosis H37Rv and the beta-ketoacyl-ACP synthase mtFabH

scientific article

Insertion site mapping for repeated elements in Mycobacterium tuberculosis

scientific article

Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach

scientific article

Mapping the fitness of Mycobacterium tuberculosis strains: a complex picture ⬇️

scientific article published on August 19, 2010

Methods to Determine Fitness in Bacteria

scientific article published on 01 January 2010

Mobile-based and open-source case detection and infectious disease outbreak management systems: a review

scientific article published in 2020

Molecular bacterial load assay, a culture-free biomarker for rapid and accurate quantification of sputum Mycobacterium tuberculosis bacillary load during treatment

scientific article published on 7 September 2011

Monitoring the therapy of pulmonary tuberculosis by nested polymerase chain reaction ⬇️

scientific article published on 01 November 1997

Monkeypox — Enhancing public health preparedness for an emerging lethal human zoonotic epidemic threat in the wake of the smallpox post-eradication era

article

Multiple drug-resistant Mycobacterium tuberculosis: evidence for changing fitness following passage through human hosts.

scientific article published in January 2002

Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser315

scientific article

New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects

scientific article published on April 2014

Novel PCR-restriction fragment length polymorphism method for determining serotypes or serogroups of Streptococcus pneumoniae isolates

scientific article published on June 2005

Origins and properties of Mycobacterium tuberculosis isolates in London

scientific article published on 01 June 2005

Polymersomes Eradicating Intracellular Bacteria

scientific article published on 09 June 2020

ProTides of N-(3-(5-(2'-deoxyuridine))prop-2-ynyl)octanamide as potential anti-tubercular and anti-viral agents.

scientific article published on 15 March 2014

Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy

scientific article

Prospective evaluation of a complex public health intervention: lessons from an initial and follow-up cross-sectional survey of the tuberculosis strain typing service in England

scientific article

Rapid Whole-Genome Sequencing of Mycobacterium tuberculosis Isolates Directly from Clinical Samples

scientific article published on 13 May 2015

Rapid detection of atypical respiratory bacterial pathogens by real-time PCR.

scientific article published on January 2013

Rapid identification of a Mycobacterium tuberculosis full genetic drug resistance profile through whole genome sequencing directly from sputum

scientific article published on 14 July 2017

Self-assembled nanoparticles as multifunctional drugs for anti-microbial therapies

scientific article published on 01 July 2014

Standardization of Nucleic Acid Tests for Clinical Measurements of Bacteria and Viruses.

scientific article published on 12 November 2014

Strategies and Challenges Involved in the Discovery of New Chemical Entities During Early-Stage Tuberculosis Drug Discovery

scientific article published on 22 March 2012

Synthesis and biological evaluation of purpurealidin E-derived marine sponge metabolites: aplysamine-2, aplyzanzine A, and suberedamines A and B.

scientific article published on 23 May 2012

The changing treatment landscape for MDR/XDR-TB — Can current clinical trials revolutionise and inform a brave new world?

scientific article published on 15 February 2019

The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China

scholarly article by Tariq A Madani published in 2020

The molecular bacterial load assay replaces solid culture for measuring early bactericidal response to antituberculosis treatment

scientific article

The use of digital PCR to improve the application of quantitative molecular diagnostic methods for tuberculosis

scientific article

The value of "inform and advise" guidance in a case of extensive tuberculosis transmission

scientific article

Tools for detection of Mycoplasma amphoriforme: a primary respiratory pathogen?

scientific article

Towards host-directed therapies for tuberculosis

scientific article

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities

scientific article published on 10 April 2012

Tuberculosis: amplification-based clinical diagnostic techniques

scientific article

Use of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial

scientific article

Versatile routes to marine sponge metabolites through benzylidene rhodanines

scientific article published on 12 December 2012

Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study

scientific article

World TB Day 2014: Reach the three million: a TB test, treatment and cure for all

scientific article published on 01 March 2014

World TB Day 2016: an interview with leading experts in tuberculosis research

scientific article (publication date: 2016)

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