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List of works by Michael Kobor

19p13.2 microduplication causes a Sotos syndrome-like phenotype and alters gene expression.

scientific article

A Role of Oxytocin Receptor Gene Brain Tissue Expression Quantitative Trait Locus rs237895 in the Intergenerational Transmission of the Effects of Maternal Childhood Maltreatment

scientific article published on 09 March 2019

A biologically-informed polygenic score identifies endophenotypes and clinical conditions associated with the insulin receptor function on specific brain regions

scientific article published on 26 March 2019

A biologically-informed polygenic score identifies endophenotypes and clinical conditions associated with the insulin receptor function on specific brain regions: Supplementary material

A motif shared by TFIIF and TFIIB mediates their interaction with the RNA polymerase II carboxy-terminal domain phosphatase Fcp1p in Saccharomyces cerevisiae

scientific article

A pooling-based approach to mapping genetic variants associated with DNA methylation

scientific article published on 24 April 2015

A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin

scientific article

A single flexible RNAPII-CTD integrates many different transcriptional programs

scientific article

Accelerated DNA methylation age in adolescent girls: associations with elevated diurnal cortisol and reduced hippocampal volume

scientific article published on 29 August 2017

Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

scientific article published on 03 March 2013

Adjusting for Cell Type Composition in DNA Methylation Data Using a Regression-Based Approach

scientific article

Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time

scientific article published on 30 January 2018

AllerGen’s 8th research conference.

scientific article published on 8 December 2016

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD.

scientific article published on 5 March 2018

An empirically driven data reduction method on the human 450K methylation array to remove tissue specific non-variable CpGs

scientific article

An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease

scientific article

An epigenetic pathway approach to investigating associations between prenatal exposure to maternal mood disorder and newborn neurobehavior

scientific article published on 01 August 2018

An essential component of a C-terminal domain phosphatase that interacts with transcription factor IIF in Saccharomyces cerevisiae

scientific article published in December 1997

An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae.

scientific article

Analysis of two birth tissues provides new insights into the epigenetic landscape of neonates born preterm

scientific article published on 11 February 2019

Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation

scientific article

Association between the FTO rs9939609 single nucleotide polymorphism and dietary adherence during a 2-year caloric restriction intervention: Exploratory analyses from CALERIE™ phase 2

Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth

scientific article

BECon: a tool for interpreting DNA methylation findings from blood in the context of brain

scientific article

Bacterial infection remodels the DNA methylation landscape of human dendritic cells

scientific article

Birth weight and postnatal microbial exposures predict the distribution of peripheral blood leukocyte subsets in young adults in the Philippines.

scientific article published on 11 October 2017

Blood and nasal epigenetics correlate with allergic rhinitis symptom development in the environmental exposure unit.

scientific article published on 29 July 2017

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes.

scientific article

Budding yeast Rtt107 prevents checkpoint hyperactivation after replicative stress by limiting DNA damage

scientific article published on 06 January 2019

CHROMATRA: a Galaxy tool for visualizing genome-wide chromatin signatures

scientific article

Cell type-specific DNA methylation in neonatal cord tissue and cord blood: a 850K-reference panel and comparison of cell types

scientific article published on 11 October 2018

Children's biobehavioral reactivity to challenge predicts DNA methylation in adolescence and emerging adulthood

scientific article published on 21 September 2018

Choice of surrogate tissue influences neonatal EWAS findings

scientific article published on 5 December 2017

Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation

scientific article

Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome.

scientific article

Comparison of DNA methylation measured by Illumina 450K and EPIC BeadChips in blood of newborns and 14-year-old children

scientific article published on 15 August 2018

Comparison of Methyl-capture Sequencing vs. Infinium 450K methylation array for methylome analysis in clinical samples

scientific article published on 19 January 2016

Concordant and discordant DNA methylation signatures of aging in human blood and brain

scientific article published on 9 May 2015

Conditional genetic interactions of RTT107, SLX4, and HRQ1 reveal dynamic networks upon DNA damage in S. cerevisiae

scientific article

Cysteinyl Leukotriene Receptor 1 and Health Effects of Particulate Exposure in Asthma

article

DNA methylation and healthy human aging

scientific article

DNA methylation as a predictor of fetal alcohol spectrum disorder.

scientific article published on 12 January 2018

DNA methylation patterns are related to co-morbidity status and circulating C-reactive protein levels in the nursing home elderly

scientific article

DNA methylation profiles of airway epithelial cells and PBMCs from healthy, atopic and asthmatic children

scientific article

DNA methylation profiling in human Huntington's disease brain.

scientific article published on 6 March 2016

DNA methylation signature of human fetal alcohol spectrum disorder.

scientific article published on 29 June 2016

DNA methylation signatures in peripheral blood mononuclear cells from a lifestyle intervention for women at midlife: A pilot RCT.

scientific article

DNA methylation signatures of chronic alcohol dependence in purified CD3+ T-cells of patients undergoing alcohol treatment

scientific article

DNA methylation, genotype and gene expression: who is driving and who is along for the ride? ⬇️

scientific article published on 29 July 2013

DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up

scientific article published on 10 January 2018

DaVIE: Database for the Visualization and Integration of Epigenetic data

scientific article

Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium

scientific article

Dephosphorylation of RNA Polymerase I by Fcp1p Is Required for Efficient rRNA Synthesis

scientific article published on 08 April 2004

Development and the epigenome: the 'synapse' of gene-environment interplay

scientific article published on January 2015

Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome

scientific article

Differences in DNA methylation of white blood cell types at birth and in adulthood reflect postnatal immune maturation and influence accuracy of cell type prediction

Different measures of "genome-wide" DNA methylation exhibit unique properties in placental and somatic tissues

scientific article

Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region

scientific article

Differential DNA methylation in peripheral blood mononuclear cells in adolescents exposed to significant early but not later childhood adversity

scientific article published on 05 February 2016

Discordance of DNA methylation variance between two accessible human tissues

scientific article

Distinct DNA methylation patterns of cognitive impairment and trisomy 21 in Down syndrome

scientific article

Dot1 and histone H3K79 methylation in natural telomeric and HM silencing

scientific article

Dynamic DNA methylation changes in the maternal oxytocin gene locus (OXT) during pregnancy predict postpartum maternal intrusiveness.

scientific article published on 14 January 2019

Eaf5/7/3 form a functionally independent NuA4 submodule linked to RNA polymerase II-coupled nucleosome recycling

scientific article

Early post-conception maternal cortisol, children's HPAA activity and DNA methylation profiles

scientific article published on 15 November 2018

Early-life socioeconomic disadvantage, not current, predicts accelerated epigenetic aging of monocytes

scientific article published on 05 July 2018

Epigenetic aging in children from a small-scale farming society in The Congo Basin: Associations with child growth and family conflict

scientific article published on 13 November 2019

Epigenetic analysis of human postmortem brain tissue

scientific article published in January 2018

Epigenetic correlates of neonatal contact in humans

scientific article

Epigenetic mechanisms mediating vulnerability and resilience to psychiatric disorders

scientific article published on 18 January 2011

Epigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescence

scientific article published on 2 September 2011

Epigenetics studies of fetal alcohol spectrum disorder: where are we now?

scientific article published on 17 February 2017

Epigenetics: A New Model for Intracellular Parasite-Host Cell Regulation

scientific article published on 30 April 2016

Exploring genetic influences underlying acute aerobic exercise effects on motor learning.

scientific article

Exploring the Genetic Basis of Human Population Differences in DNA Methylation and their Causal Impact on Immune Gene Regulation

article

Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation

article

Exposure to childhood abuse is associated with human sperm DNA methylation

scientific article published on 02 October 2018

Extensive epigenetic reprogramming in human somatic tissues between fetus and adult

scientific article

Factors underlying variable DNA methylation in a human community cohort

scientific article

Fetal alcohol spectrum disorders: gene-environment interactions, predictive biomarkers, and the relationship between structural alterations in the brain and functional outcomes

scientific article published on March 2011

GAL4 Is Regulated by the RNA Polymerase II Holoenzyme–Associated Cyclin-Dependent Protein Kinase SRB10/CDK8

scientific article published on 01 May 1999

Genome-Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow-up

scientific article published on 30 November 2016

Genome-wide analysis of DNA methylation in relation to socioeconomic status during development and early adulthood

scientific article published on 16 February 2019

Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chip

scientific article

Genomewide DNA methylation dynamics upon diesel exhaust exposure in asthmatics

scientific article published on 3 March 2014

Glutaminase Deficiency Caused by Short Tandem Repeat Expansion in

scientific article published on 01 April 2019

Greater inflammatory activity and blunted glucocorticoid signaling in monocytes of chronically stressed caregivers

scientific article published on 02 June 2014

H2A.Z and DNA methylation: irreconcilable differences

scientific article published on 11 March 2009

HIF3A association with adiposity: the story begins before birth

scientific article published on 26 May 2015

Healthy Foundations Study: a randomised controlled trial to evaluate biological embedding of early-life experiences.

scientific article

High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8.

scientific article

Histone H3 lysine 36 methylation targets the Isw1b remodeling complex to chromatin

scientific article published on 2 July 2012

Histone H3K4 demethylation is negatively regulated by histone H3 acetylation in Saccharomyces cerevisiae

scientific article

How the epigenome contributes to the development of psychiatric disorders

scientific article published on May 2010

Human placental-specific epipolymorphism and its association with adverse pregnancy outcomes

scientific article

Identification of a nucleic acid-binding region within the largest subunit of Drosophila melanogaster RNA polymerase II.

scientific article published on February 1993

Improving cell mixture deconvolution by identifying optimal DNA methylation libraries (IDOL).

scientific article

Infinium monkeys: Infinium 450K array for the Cynomolgus macaque (Macaca fascicularis).

scientific article published on 8 May 2014

Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation

scientific article published on 10 May 2016

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.

scientific article published on 11 June 2019

Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation

scientific article published on 02 January 2019

Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator

scientific article published on 24 November 2004

Key functional regions in the histone variant H2A.Z C-terminal docking domain

scientific article published on 26 July 2011

Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation

scientific article

Leishmania donovani infection causes distinct epigenetic DNA methylation changes in host macrophages

scientific article (publication date: October 2014)

Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation

scientific article published on 13 August 2009

Longitudinal study of surrogate aging measures during human immunodeficiency virus seroconversion

scientific article

Loss of H3 K79 trimethylation leads to suppression of Rtt107-dependent DNA damage sensitivity through the translesion synthesis pathway

scientific article published on September 2010

Low birth weight associates with hippocampal gene expression

scientific article published on 11 January 2016

Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling

scholarly article

MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription-replication conflicts

scientific article published on 19 September 2019

Maintenance of heterochromatin boundary and nucleosome composition at promoters by the Asf1 histone chaperone and SWR1-C chromatin remodeler in Saccharomyces cerevisiae.

scientific article

Maternal blood contamination of collected cord blood can be identified using DNA methylation at three CpGs

scientific article

Maternal early life adversities and the offspring's epigenome: A M.A.V.A.N. project

scholarly article by Eva Unternaehrer et al published November 2015 in Psychoneuroendocrinology

Maternal warmth buffers the effects of low early-life socioeconomic status on pro-inflammatory signaling in adulthood.

scientific article

Molecular pathways underpinning ethanol-induced neurodegeneration

scientific article

NMR structure of a complex containing the TFIIF subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1

scientific article

NMR structure of the amino-terminal domain from the Tfb1 subunit of TFIIH and characterization of its phosphoinositide and VP16 binding sites

scientific article

Natural variation in maternal care and cross-tissue patterns of oxytocin receptor gene methylation in rats.

scientific article

NuA4 and SWR1-C: two chromatin-modifying complexes with overlapping functions and components

scientific article published on October 2009

Nucleated red blood cells impact DNA methylation and expression analyses of cord blood hematopoietic cells

scientific article

Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain

scientific article

PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores

scholarly article by Lawrence M Chen published in August 2018

Perinatally acquired HIV infection accelerates epigenetic aging in South African adolescents

article

Population-specificity of human DNA methylation

scientific article

Prenatal Alcohol Exposure: Profiling Developmental DNA Methylation Patterns in Central and Peripheral Tissues

scientific article published on 04 December 2018

Prenatal alcohol exposure alters gene expression in the rat brain: Experimental design and bioinformatic analysis of microarray data.

scientific article

Prenatal alcohol exposure alters steady-state and activated gene expression in the adult rat brain.

scientific article published on February 2015

Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates

scientific article

Principles and Challenges of Applying Epigenetic Epidemiology to Psychology

scientific article published on 16 October 2017

Purification and assay of Saccharomyces cerevisiae phosphatase that acts on the C-terminal domain of the largest subunit of RNA polymerase II.

scientific article

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

scientific article published on January 2012

RECQ-like helicases Sgs1 and BLM regulate R-loop-associated genome instability

scientific article published on 17 October 2017

RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach

scientific article

Reading chromatin: insights from yeast into YEATS domain structure and function.

scientific article published on October 2010

Regulation of transcription elongation by phosphorylation

scientific article

Reply to Suderman et al.: Importance of accounting for blood cell composition in epigenetic studies

scientific article published in April 2013

Reproduction predicts shorter telomeres and epigenetic age acceleration among young adult women

Reversal of epigenetic aging and immunosenescent trends in humans

scientific article published on 08 September 2019

Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expression

scientific article published on 11 December 2021

Roles for H2A.Z and its acetylation in GAL1 transcription and gene induction, but not GAL1-transcriptional memory

scientific article

Rtt107 BRCT domains act as a targeting module in the DNA damage response.

scientific article published on 10 November 2015

Rtt107 is required for recruitment of the SMC5/6 complex to DNA double strand breaks

scientific article published on 3 June 2011

Short-term diesel exhaust inhalation in a controlled human crossover study is associated with changes in DNA methylation of circulating mononuclear cells in asthmatics

scientific article

Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4

scientific article

Social and physical environments early in development predict DNA methylation of inflammatory genes in young adulthood

scientific article

Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis

scientific article published on 23 September 2013

Solution structure of the carboxyl-terminal domain of RAP74 and NMR characterization of the FCP1-binding sites of RAP74 and human TFIIB

scientific article (publication date: 18 February 2003)

Splitting the task: Ubp8 and Ubp10 deubiquitinate different cellular pools of H2BK123.

scientific article published on November 2011

Spread of X-chromosome inactivation into autosomal sequences: role for DNA elements, chromatin features and chromosomal domains

scientific article

Systematic evaluation and validation of reference and library selection methods for deconvolution of cord blood DNA methylation data

scientific article published on 27 August 2019

Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array

scientific article published on 16 October 2018

The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma

scientific article

The Intersection Of Aging Biology and The Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop

scientific article

The RNAPII-CTD Maintains Genome Integrity through Inhibition of Retrotransposon Gene Expression and Transposition

scientific article published on 23 October 2015

The biological embedding of early-life socioeconomic status and family adversity in children's genome-wide DNA methylation

scientific article published on 23 October 2018

The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory

scientific article

The early care environment and DNA methylome variation in childhood

scientific article published on 01 August 2018

The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes

scientific article

The epigenomic landscape of African rainforest hunter-gatherers and farmers

scientific article

The era of integrative genomics: more data or better methods?

scientific article

The molecular mechanism of a cis-regulatory adaptation in yeast

scientific article

The relation between DNA methylation patterns and serum cytokine levels in community-dwelling adults: a preliminary study

scientific article

The specificity and topology of chromatin interaction pathways in yeast

scientific article

Trends in DNA Methylation with Age Replicate Across Diverse Human Populations

scientific article published on 22 May 2017

Variability in DNA methylation at the serotonin transporter gene promoter: epigenetic mechanism or cell-type artifact?

article

Variably methylated regions in the newborn epigenome: environmental, genetic and combined influences

Worldwide patterns of human epigenetic variation

scientific article published on 28 August 2017

YEATS domain proteins: a diverse family with many links to chromatin modification and transcription.

scientific article

funtooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types

scientific article

p300/CBP-associated factor selectively regulates the extinction of conditioned fear

scientific article

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