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List of works by Richard T. Libby

Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1

scientific article

Adaptive optics retinal imaging in the living mouse eye

scientific article

Adding metabolomics to the toolbox for studying retinal disease.

scientific article published on 21 June 2013

An ocular glymphatic clearance system removes β-amyloid from the rodent eye

scientific article published on 01 March 2020

Assessment of intrinsic and extrinsic signaling pathway in excitotoxic retinal ganglion cell death.

scientific article

Author Correction: Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death

scholarly article published in Cell Death and Disease

Axon injury signaling and compartmentalized injury response in glaucoma

scientific article published on 10 July 2019

BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons

scientific article published on April 2009

BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina.

scientific article published on 15 July 2011

BCL2L1 (BCL-X) promotes survival of adult and developing retinal ganglion cells

scientific article

Cdh23 mutations in the mouse are associated with retinal dysfunction but not retinal degeneration ⬇️

scientific article published on December 1, 2003

Ciliary margin-derived BMP4 does not have a major role in ocular development.

scientific article published on 8 May 2018

Col4a1 mutations cause progressive retinal neovascular defects and retinopathy

scientific article (publication date: 2016)

Complex genetics of glaucoma susceptibility

scientific article

DBA/2J mice are susceptible to diabetic nephropathy and diabetic exacerbation of IOP elevation.

scientific article

DDIT3 (CHOP) contributes to retinal ganglion cell somal loss but not axonal degeneration in DBA/2J mice

scientific article published on 10 October 2019

DLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injury

scientific article

Datgan, a reusable software system for facile interrogation and visualization of complex transcription profiling data

scientific article

Deficiency in Bim, Bid and Bbc3 (Puma) do not prevent axonal injury induced death

scientific article published on 21 September 2012

Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective.

scientific article

Endoplasmic reticulum stress as a primary pathogenic mechanism leading to age-related macular degeneration

scientific article

Endothelin 1-induced retinal ganglion cell death is largely mediated by JUN activation

scientific article published on 26 September 2020

G-Protein-Coupled Receptor-2-Interacting Protein-1 Controls Stalk Cell Fate by Inhibiting Delta-like 4-Notch1 Signaling.

scientific article

Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma

scientific article

Glaucoma: thinking in new ways-a rôle for autonomous axonal self-destruction and other compartmentalised processes?

scientific article

High-dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucoma

scientific article

Identification of the cellular source of laminin beta2 in adult and developing vertebrate retinae

scientific article published on 01 December 1997

In-vivo imaging of retinal nerve fiber layer vasculature: imaging histology comparison

scientific article published on 23 August 2009

Inducible nitric oxide synthase, Nos2, does not mediate optic neuropathy and retinopathy in the DBA/2J glaucoma model

scientific article

Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration

scientific article published on September 2005

Intravitreal injection of AAV2 transduces macaque inner retina

scientific article

Intrinsic axonal degeneration pathways are critical for glaucomatous damage.

scientific article published on 18 January 2012

JUN is important for ocular hypertension-induced retinal ganglion cell degeneration.

scientific article

JUN regulates early transcriptional responses to axonal injury in retinal ganglion cells

scientific article published on 3 May 2013

Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice.

scientific article published on 13 June 2018

KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS.

scientific article published on 4 September 2017

MATH5 controls the acquisition of multiple retinal cell fates.

scientific article published on 18 November 2010

Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death

article

Modification of ocular defects in mouse developmental glaucoma models by tyrosinase

scientific article published in March 2003

Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma

scientific article

Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection

scientific article published on January 2008

Mutations in a P-type ATPase gene cause axonal degeneration

scientific article (publication date: 2012)

Myosin VI is required for normal retinal function

scientific article published in July 2005

Myosin Va is required for normal photoreceptor synaptic activity

scientific journal article

Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye

scientific journal article

Novel axon projection after stress and degeneration in the Dscam mutant retina

scientific article published on 9 December 2015

Ocular fibroblast diversity: implications for inflammation and ocular wound healing

scientific article

Optical properties of the mouse eye.

scientific article published on 28 February 2011

Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival

scientific article

Pou4f1 and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice.

scientific article

Quantitative measurement of retinal ganglion cell populations via histology-based random forest classification

scientific article published on 13 October 2015

Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma

scientific article published on 19 March 2012

Reduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutations

scientific journal article

Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice

scientific article published on October 2005

Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury.

scientific article

Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes

scientific journal article

Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice.

scientific article

The Bcl-2 family member BIM has multiple glaucoma-relevant functions in DBA/2J mice

scientific article

The Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65

scientific journal article

Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury

scientific article published on 2 October 2017

Trabecular meshwork morphogenesis: A comparative analysis of wildtype and anterior segment dysgenesis mouse models

scientific article published on 13 February 2018

Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells.

scientific article published on 06 May 2013

Transcriptional control of retinal ganglion cell death after axonal injury

scientific article published on 16 March 2022

Tumor necrosis factor alpha has an early protective effect on retinal ganglion cells after optic nerve crush.

scientific article

Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities

scientific article

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