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List of works by Damian J. Tyler

(31)P cardiac magnetic resonance spectroscopy during leg exercise at 3 Tesla

scientific article published on 21 August 2009

A 3D hybrid-shot spiral sequence for hyperpolarized 13C imaging

scientific article published on 07 September 2020

A comparison of cardiac (31)P MRS at 1.5 and 3 T.

scientific article published in October 2008

A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects

scientific article published on 26 January 2011

Accelerated human cardiac diffusion tensor imaging using simultaneous multislice imaging.

scientific article published on 21 March 2014

Adenosine monophosphate-activated protein kinase activation, substrate transporter translocation, and metabolism in the contracting hyperthyroid rat heart

scientific article published on 25 November 2009

Antenatal determination of fetal brain activity in response to an acoustic stimulus using functional magnetic resonance imaging.

scientific article published on February 2001

Assessing the effect of hypoxia on cardiac metabolism using hyperpolarized 13 C magnetic resonance spectroscopy

scientific article published on 15 May 2019

Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS

scientific article published on 24 July 2018

Assessment of Left Atrial Volumes at 1.5 Tesla and 3 Tesla Using FLASH and SSFP Cine Imaging

scientific article published on 01 July 2007

Assessment of Metformin induced changes in cardiac redox state using hyperpolarized[1-13C]pyruvate

scientific article published on 27 January 2016

Assessment of Metformin-Induced Changes in Cardiac and Hepatic Redox State Using Hyperpolarized[1-13C]Pyruvate

scientific article published on 25 August 2016

Bone marrow-derived stromal cells home to and remain in the infarcted rat heart but fail to improve function: an in vivo cine-MRI study.

scientific article published on 6 June 2008

C Pyruvate Transport Across the Blood-Brain Barrier in Preclinical Hyperpolarised MRI

scientific article published in Scientific Reports

CINE-MR imaging of the normal and infarcted rat heart using an 11.7 T vertical bore MR system

scientific article published on 01 January 2006

Cardiac 31 P MRS analysis development: Improved fitting of 2, 3 DPG

article

Cardiac Dysfunction and Metabolic Inflexibility in a Mouse Model of Diabetes Without Dyslipidemia.

scientific article published on 2 April 2018

Cardiac applications of hyperpolarised magnetic resonance

scientific article published on 31 May 2018

Cardiac cine MR-imaging at 3T: FLASH vs SSFP.

scientific article published in January 2006

Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function.

scientific article

Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin.

scientific article published on 24 September 2013

Cardiac perfusion imaging using hyperpolarized (13)C urea using flow sensitizing gradients.

scientific article published on 20 May 2015

Cardiac response to hypobaric hypoxia: persistent changes in cardiac mass, function, and energy metabolism after a trek to Mt. Everest Base Camp

article

Cardiovascular Applications of Hyperpolarized MRI.

scientific article published on 19 January 2011

Cine-MRI versus two-dimensional echocardiography to measure in vivo left ventricular function in rat heart

scientific article

Clinical Cardiovascular Applications of Hyperpolarized Magnetic Resonance

scientific article published on 01 April 2020

Clinical implications of cardiac hyperpolarized magnetic resonance imaging

scientific article

Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment

article

Determination of cardiac volumes and mass with FLASH and SSFP cine sequences at 1.5 vs. 3 Tesla: A validation study

scientific article published on 01 August 2006

Determining the in vivo regulation of cardiac pyruvate dehydrogenase based on label flux from hyperpolarised [1‐13C]pyruvate ⬇️

scientific article published on March 8, 2011

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI

scientific article published on 19 November 2020

Echo-planar magnetic resonance imaging of Gaviscon alginate rafts in-vivo

scientific article published in October 2002

Effects of Catecholamine Stress on Diastolic Function and Myocardial Energetics in Obesity

scientific article published on 24 February 2012

Effects of contrast agents on relaxation properties of 31P metabolites

scientific article published on 08 October 2020

Effects of weight loss on myocardial energetics and diastolic function in obesity

scientific article published on 27 December 2012

Endurance exercise training blunts the deleterious effect of high-fat feeding on whole body efficiency

scientific article published on June 2011

Exacerbation of cardiac energetic impairment during exercise in hypertrophic cardiomyopathy: a potential mechanism for diastolic dysfunction

scientific article published on 18 May 2015

Fast, high-resolution in vivo cine magnetic resonance imaging in normal and failing mouse hearts on a vertical 11.7 T system

scientific article published in December 2003

First-pass perfusion CMR two days after infarction predicts severity of functional impairment six weeks later in the rat heart ⬇️

scientific article published on August 3, 2011

Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.

scientific article published in March 2012

Functional Magnetic Resonance Imaging (Magnetization Transfer) and Stereological Analysis of Human Placentae in Normal Pregnancy and in Pre-eclampsia and Intrauterine Growth Restriction

scientific article published on 01 May 2004

High-resolution, multicontrast three-dimensional-MRI characterizes atherosclerotic plaque composition in ApoE-/- mice ex vivo

scientific article published on 01 December 2004

Human hippocampal energy metabolism is impaired during cognitive activity in a lipid infusion model of insulin resistance ⬇️

scientific article published on February 15, 2013

Hyperpolarised magnetic resonance for in vivo real-time metabolic imaging

scientific article published on 27 April 2018

Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart.

scientific article published on 19 December 2012

Hyperpolarized 13C and 31P magnetic resonance spectroscopy identify pyruvate dehydrogenase as a therapeutic target in obesity cardiomyopathy

Hyperpolarized <sup>13</sup> C magnetic resonance imaging for noninvasive assessment of tissue inflammation

scientific article published on 08 December 2020

Hyperpolarized C MRI: Path to Clinical Translation in Oncology

scientific article published on 23 November 2018

Hyperpolarized [1,4-13C2]Fumarate Enables Magnetic Resonance-Based Imaging of Myocardial Necrosis

scientific article published on 8 December 2017

Hyperpolarized butyrate: a metabolic probe of short chain fatty acid metabolism in the heart

scientific article published on 24 June 2013

Hyperpolarized ketone body metabolism in the rat heart.

scientific article published on 10 April 2018

Hyperpolarized magnetic resonance: a novel technique for the in vivo assessment of cardiovascular disease.

scientific article

Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy.

scientific article published on 8 September 2014

In vivo MRI characterization of progressive cardiac dysfunction in the mdx mouse model of muscular dystrophy.

scientific article published on 3 January 2012

In vivo alterations in cardiac metabolism and function in the spontaneously hypertensive rat heart

scientific article published on 16 May 2012

In vivo assessment of cardiac metabolism and function in the abdominal aortic banding model of compensated cardiac hypertrophy

scientific article

In vivo cardiac 1H-MRS in the mouse

scientific article

In vivo mouse cardiac hyperpolarized magnetic resonance spectroscopy

scientific article published on 18 February 2013

Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation

scientific article published on 17 November 2015

Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study

scientific article published on 20 March 2015

Inhibition of sarcolemmal FAT/CD36 by sulfo-N-succinimidyl oleate rapidly corrects metabolism and restores function in the diabetic heart following hypoxia/reoxygenation

scientific article

Iron particles for noninvasive monitoring of bone marrow stromal cell engraftment into, and isolation of viable engrafted donor cells from, the heart

scientific article published on 20 April 2006

MEN1 gene replacement therapy reduces proliferation rates in a mouse model of pituitary adenomas

scientific article

Magnetic resonance imaging evaluation of remodeling by cardiac elastomeric tissue scaffold biomaterials in a rat model of myocardial infarction

scientific article

Magnetic resonance imaging for the study of ovarian follicles in the mouse

scientific article published on 13 August 2012

Magnetic resonance imaging with ultrashort TE (UTE) PULSE sequences: technical considerations

scientific article

Mapping of intracellular pH in the in vivo rodent heart using hyperpolarized [1-13C]pyruvate.

scientific article

Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy study

scientific article

Metabolic imaging of acute and chronic infarction in the perfused rat heart using hyperpolarised [1-13C]pyruvate.

scientific article published on 14 June 2013

Myocardial energy shortage and unmet anaplerotic needs in the fasted long-chain acyl-CoA dehydrogenase knockout mouse

scientific article

Myocardial substrate metabolism in obesity ⬇️

scientific article published on October 16, 2012

Myometrial and placental artery reactivity alone cannot explain reduced placental perfusion in pre-eclampsia and intrauterine growth restriction

scientific article published in October 2003

Non-Invasive Immuno-Metabolic Cardiac Inflammation Imaging Using Hyperpolarized Magnetic Resonance.

scientific article published on 12 February 2018

Noninvasive In Vivo Assessment of Cardiac Metabolism in the Healthy and Diabetic Human Heart Using Hyperpolarized 13C MRI

scientific article published on 05 February 2020

Novel MRI method to detect altered left ventricular ejection and filling patterns in rodent models of disease

scientific article

Novel ketone diet enhances physical and cognitive performance

scientific article published on 15 August 2016

Ongoing dual-angle measurements for the correction of partial saturation in 31P MR spectroscopy.

scientific article

Pyruvate dehydrogenase as a therapeutic target for obesity cardiomyopathy

scientific article

Quantifying normal human brain metabolism using hyperpolarized [1-C]pyruvate and magnetic resonance imaging

scientific article published on 11 January 2019

Rapid and accurate measurement of transverse relaxation times using a single shot multi-echo echo-planar imaging sequence

scientific article

Rapid quantitation of magnetization transfer using pulsed off-resonance irradiation and echo planar imaging

scientific article published in January 2005

Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.

scientific article published on 27 March 2009

Rearrangement of atrial bundle architecture and consequent changes in anisotropy of conduction constitute the 3-dimensional substrate for atrial fibrillation

scientific article published on 22 August 2013

Reproducibility of 31P cardiac magnetic resonance spectroscopy at 3 T.

scientific article published in May 2009

Robust and high resolution hyperpolarized metabolic imaging of the rat heart at 7 T with 3D spectral-spatial EPI

scientific article

Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study.

scientific article

Science to Practice: Hyperpolarized Metabolic MR Imaging--The Light at the End of the Tunnel for Clinical (13)C MR Spectroscopy?

scientific article published in March 2016

Short-term consumption of a high-fat diet impairs whole-body efficiency and cognitive function in sedentary men

scientific article published on 24 November 2010

Simultaneous assessment of cardiac metabolism and perfusion using copolarized [1-13 C]pyruvate and 13 C-urea

scientific article published on 7 January 2016

Simultaneous in vivo assessment of cardiac and hepatic metabolism in the diabetic rat using hyperpolarized MRS.

scientific article published on 25 October 2016

Spiral artery blood volume in normal pregnancies and those compromised by pre-eclampsia

scientific article published on 01 May 2008

Susceptibility-induced distortion correction in hyperpolarized echo planar imaging.

scientific article published on 19 July 2017

Systemic inflammatory response reactivates immune-mediated lesions in rat brain.

scientific article

The Role of AMPK Activation for Cardioprotection in Doxorubicin-Induced Cardiotoxicity

scientific article published on 01 April 2020

The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study.

scientific article

The effect of high-altitude on human skeletal muscle energetics: P-MRS results from the Caudwell Xtreme Everest expedition

scientific article (publication date: 19 May 2010)

The effect of hyperpolarized tracer concentration on myocardial uptake and metabolism

scientific article published in May 2009

The reproducibility of 31-phosphorus MRS measures of muscle energetics at 3 Tesla in trained men.

scientific article

The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism

scientific article published on 15 July 2016

Ultrashort TE chemical shift imaging (UTE-CSI).

scientific article published in February 2005

Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS.

scientific article published on 26 August 2010

Varying degrees of ventricular unloading in the heterotopic rat heart transplant model demonstrated by magnetic resonance imaging

scientific article published on December 2014

Weighted averaging in spectroscopic studies improves statistical power.

scientific article

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