List of works - Nicolas Cagnard

A lineage of myeloid cells independent of Myb and hematopoietic stem cells

scientific article (publication date: 6 April 2012)

A rare castration-resistant progenitor cell population is highly enriched in Pten-null prostate tumours

scientific article

A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

scientific article published on 01 July 2019

AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages

scientific article

Acellular therapeutic approach for heart failure: in vitro production of extracellular vesicles from human cardiovascular progenitors.

scientific article published on 6 February 2018

Angiotensin II facilitates breast cancer cell migration and metastasis

scientific article

Atorvastatin reduces β-Adrenergic dysfunction in rats with diabetic cardiomyopathy

scientific article published on 20 July 2017

B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells

scientific article

BAFF and CD4+ T cells are major survival factors for long-lived splenic plasma cells in a B-cell-depletion context.

scientific article published on 29 January 2018

Cell cloning-based transcriptome analysis in Rett patients: relevance to the pathogenesis of Rett syndrome of new human MeCP2 target genes

scientific article published on 21 June 2010

Cell cloning-based transcriptome analysis in cyclin-dependent kinase-like 5 mutation patients with severe epileptic encephalopathy

scientific article published on 24 November 2010

Combined loss of cRel/p50 subunits of NF-κB leads to impaired innate host response in sepsis

article

Combined transcriptomic-(1)H NMR metabonomic study reveals that monoethylhexyl phthalate stimulates adipogenesis and glyceroneogenesis in human adipocytes.

scientific article

Comprehensive linkage and association analyses identify haplotype, near to the TNFSF15 gene, significantly associated with spondyloarthritis

scientific article published on 19 June 2009

Critical role of cRel subunit of NF-κB in sepsis survival

scientific article

DNA microarray allows molecular profiling of rheumatoid arthritis and identification of pathophysiological targets.

scientific article

Early Acute Microvascular Kidney Transplant Rejection in the Absence of Anti-HLA Antibodies Is Associated with Preformed IgG Antibodies against Diverse Glomerular Endothelial Cell Antigens

scientific article published on 08 March 2019

Early born neurons are abnormally positioned in the doublecortin knockout hippocampus

scientific article published on 22 December 2016

Emergence of long-lived autoreactive plasma cells in the spleen of primary warm auto-immune hemolytic anemia patients treated with rituximab

scientific article

FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase

scientific article

Failure to confirm coxsackievirus infection in primary Sjögren's syndrome.

scientific article

Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1).

scientific article

Gene expression profile in the salivary glands of primary Sjögren's syndrome patients before and after treatment with rituximab

scientific article published on August 2010

Gene expression profiling provides insights into the pathways involved in solid pseudopapillary neoplasm of the pancreas

scientific article published in June 2009

Generation of adult human T-cell progenitors for immunotherapeutic applications

scientific article published on 2 December 2017

Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression

scientific journal article

Genotoxic signature in cord blood cells of newborns exposed in utero to a Zidovudine-based antiretroviral combination

scientific article published on 4 April 2013

Heterogeneous CD3 expression levels in differing T cell subsets correlate with the in vivo anti-CD3-mediated T cell modulation

scientific article published on 2 February 2015

Homogeneous Inflammatory Gene Profiles Induced in Human Dermal Fibroblasts in Response to the Three Main Species of Borrelia burgdorferi sensu lato

scientific article

Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors

scientific article published on 9 September 2010

IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

scientific article

Identification of a human splenic marginal zone B cell precursor with NOTCH2-dependent differentiation properties

scientific article

Identification of a human splenic marginal zone B cell precursor with NOTCH2-dependent differentiation properties

Identification of molecular pathways involved in oxaliplatin-associated sinusoidal dilatation

scientific article published on 24 December 2011

Implication of clusterin in TNF-α response of rheumatoid synovitis: lesson from in vitro knock-down of clusterin in human synovial fibroblast cells

Insights into the pathogenesis of systemic sclerosis based on the gene expression profile of progenitor-derived endothelial cells

article

Interleukin-15-Dependent T-Cell-like Innate Intraepithelial Lymphocytes Develop in the Intestine and Transform into Lymphomas in Celiac Disease

scientific article published on 31 August 2016

Interleukin-32, CCL2, PF4F1 and GFD10 are the only cytokine/chemokine genes differentially expressed by in vitro cultured rheumatoid and osteoarthritis fibroblast-like synoviocytes

article

KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes

scientific article

Klhl6 Deficiency Impairs Transitional B Cell Survival and Differentiation.

scientific article

Lenalidomide-mediated erythroid improvement in non-del(5q) myelodysplastic syndromes is associated with bone marrow immuno-remodeling

scientific article published on 3 October 2017

Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells

scientific article published on 4 February 2013

Mutations in ACTRT1 and its enhancer RNA elements lead to aberrant activation of Hedgehog signaling in inherited and sporadic basal cell carcinomas.

scientific article

Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects

scientific article

Nuclear outsourcing of RNA interference components to human mitochondria

scientific article (publication date: 2011)

Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin

scientific article published on 22 February 2018

Regulatory T cells delay disease progression in Alzheimer-like pathology.

scientific article

Reverse interferon signature is characteristic of antigen-presenting cells in human and rat spondyloarthritis.

scientific article

Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program.

scientific article

Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders.

scientific article published on 19 June 2018

Srf-Dependent Paracrine Signals Produced by Myofibers Control Satellite Cell-Mediated Skeletal Muscle Hypertrophy

scientific article published on 01 January 2012

Synergy of chemotherapy and immunotherapy revealed by a genome-scale analysis of murine tuberculosis

scientific article published on 16 February 2015

Systematic candidate gene investigations in the SPA2 locus (9q32) show an association between TNFSF8 and susceptibility to spondylarthritis

article

TCL1 expression patterns in Waldenström macroglobulinemia

scientific article published on 23 October 2015

Tetratricopeptide repeat domain 7A is a nuclear factor that modulates transcription and chromatin structure

scientific article published on 13 November 2018

The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model

scientific article

The transcription factor Srf regulates hematopoietic stem cell adhesion

scientific journal article

The transforming growth factor-α and cyclin D1 genes are direct targets of β-catenin signaling in hepatocyte proliferation

article

Ttc7a regulates hematopoietic stem cell functions while controlling the stress-induced response

scientific article published on 19 April 2019

Two persistent organic pollutants which act through different xenosensors (alpha-endosulfan and 2,3,7,8 tetrachlorodibenzo-p-dioxin) interact in a mixture and downregulate multiple genes involved in human hepatocyte lipid and glucose metabolism.

scientific article published on 6 July 2015

Type I interferon-mediated autoinflammation due to DNase II deficiency

scientific article published on 19 December 2017

UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells.

scientific article published on 21 November 2017

Variability of response to methadone: genome-wide DNA methylation analysis in two independent cohorts

scientific article published on 21 January 2016

List of works by Nicolas Cagnard

A lineage of myeloid cells independent of Myb and hematopoietic stem cells

A rare castration-resistant progenitor cell population is highly enriched in Pten-null prostate tumours

A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages

Acellular therapeutic approach for heart failure: in vitro production of extracellular vesicles from human cardiovascular progenitors.

Angiotensin II facilitates breast cancer cell migration and metastasis

Atorvastatin reduces β-Adrenergic dysfunction in rats with diabetic cardiomyopathy

B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells

BAFF and CD4+ T cells are major survival factors for long-lived splenic plasma cells in a B-cell-depletion context.

Cell cloning-based transcriptome analysis in Rett patients: relevance to the pathogenesis of Rett syndrome of new human MeCP2 target genes

Cell cloning-based transcriptome analysis in cyclin-dependent kinase-like 5 mutation patients with severe epileptic encephalopathy

Combined loss of cRel/p50 subunits of NF-κB leads to impaired innate host response in sepsis

Combined transcriptomic-(1)H NMR metabonomic study reveals that monoethylhexyl phthalate stimulates adipogenesis and glyceroneogenesis in human adipocytes.

Comprehensive linkage and association analyses identify haplotype, near to the TNFSF15 gene, significantly associated with spondyloarthritis

Critical role of cRel subunit of NF-κB in sepsis survival

DNA microarray allows molecular profiling of rheumatoid arthritis and identification of pathophysiological targets.

Early Acute Microvascular Kidney Transplant Rejection in the Absence of Anti-HLA Antibodies Is Associated with Preformed IgG Antibodies against Diverse Glomerular Endothelial Cell Antigens

Early born neurons are abnormally positioned in the doublecortin knockout hippocampus

Emergence of long-lived autoreactive plasma cells in the spleen of primary warm auto-immune hemolytic anemia patients treated with rituximab

FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase

Failure to confirm coxsackievirus infection in primary Sjögren's syndrome.

Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1).

Gene expression profile in the salivary glands of primary Sjögren's syndrome patients before and after treatment with rituximab

Gene expression profiling provides insights into the pathways involved in solid pseudopapillary neoplasm of the pancreas

Generation of adult human T-cell progenitors for immunotherapeutic applications

Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression

Genotoxic signature in cord blood cells of newborns exposed in utero to a Zidovudine-based antiretroviral combination

Heterogeneous CD3 expression levels in differing T cell subsets correlate with the in vivo anti-CD3-mediated T cell modulation

Homogeneous Inflammatory Gene Profiles Induced in Human Dermal Fibroblasts in Response to the Three Main Species of Borrelia burgdorferi sensu lato

Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors

IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

Identification of a human splenic marginal zone B cell precursor with NOTCH2-dependent differentiation properties

Identification of a human splenic marginal zone B cell precursor with NOTCH2-dependent differentiation properties

Identification of molecular pathways involved in oxaliplatin-associated sinusoidal dilatation

Implication of clusterin in TNF-α response of rheumatoid synovitis: lesson from in vitro knock-down of clusterin in human synovial fibroblast cells

Insights into the pathogenesis of systemic sclerosis based on the gene expression profile of progenitor-derived endothelial cells

Interleukin-15-Dependent T-Cell-like Innate Intraepithelial Lymphocytes Develop in the Intestine and Transform into Lymphomas in Celiac Disease

Interleukin-32, CCL2, PF4F1 and GFD10 are the only cytokine/chemokine genes differentially expressed by in vitro cultured rheumatoid and osteoarthritis fibroblast-like synoviocytes

KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes

Klhl6 Deficiency Impairs Transitional B Cell Survival and Differentiation.

Lenalidomide-mediated erythroid improvement in non-del(5q) myelodysplastic syndromes is associated with bone marrow immuno-remodeling

Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells

Mutations in ACTRT1 and its enhancer RNA elements lead to aberrant activation of Hedgehog signaling in inherited and sporadic basal cell carcinomas.

Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects

Nuclear outsourcing of RNA interference components to human mitochondria

Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin

Regulatory T cells delay disease progression in Alzheimer-like pathology.

Reverse interferon signature is characteristic of antigen-presenting cells in human and rat spondyloarthritis.

Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program.

Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders.

Srf-Dependent Paracrine Signals Produced by Myofibers Control Satellite Cell-Mediated Skeletal Muscle Hypertrophy

Synergy of chemotherapy and immunotherapy revealed by a genome-scale analysis of murine tuberculosis

Systematic candidate gene investigations in the SPA2 locus (9q32) show an association between TNFSF8 and susceptibility to spondylarthritis

TCL1 expression patterns in Waldenström macroglobulinemia

Tetratricopeptide repeat domain 7A is a nuclear factor that modulates transcription and chromatin structure

The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model

The transcription factor Srf regulates hematopoietic stem cell adhesion

The transforming growth factor-α and cyclin D1 genes are direct targets of β-catenin signaling in hepatocyte proliferation

Ttc7a regulates hematopoietic stem cell functions while controlling the stress-induced response

Two persistent organic pollutants which act through different xenosensors (alpha-endosulfan and 2,3,7,8 tetrachlorodibenzo-p-dioxin) interact in a mixture and downregulate multiple genes involved in human hepatocyte lipid and glucose metabolism.

Type I interferon-mediated autoinflammation due to DNase II deficiency

UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells.

Variability of response to methadone: genome-wide DNA methylation analysis in two independent cohorts