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List of works by Richard Y-C Huang

A novel mechanism for regulating the activity of proliferating cell nuclear antigen by a small protein

scientific article

An Integrated Approach for Determining a Protein-Protein Binding Interface in Solution and an Evaluation of Hydrogen-Deuterium Exchange Kinetics for Adjudicating Candidate Docking Models

scientific article published on 22 November 2019

Characterization of Aggregation Propensity of a Human Fc-Fusion Protein Therapeutic by Hydrogen/Deuterium Exchange Mass Spectrometry

scientific article

Characterization of antibody-drug conjugates by mass spectrometry: advances and future trends.

scientific article published on 11 April 2016

Chromatography-based methods for determining molar extinction coefficients of cytotoxic payload drugs and drug antibody ratios of antibody drug conjugates

scientific article published on 26 May 2016

Conformational Assessment of Adnectin and Adnectin-Drug Conjugate by Hydrogen/Deuterium Exchange Mass Spectrometry

scientific article published on 07 May 2018

Effects of desialylation on human α1-acid glycoprotein-ligand interactions.

scientific article published on 27 September 2013

Epitope and Paratope Mapping of PD-1/Nivolumab by Mass Spectrometry-based Hydrogen/Deuterium Exchange, Cross-linking, and Molecular Docking

scientific article published on 22 May 2020

Fast photochemical oxidation of proteins (FPOP) maps the epitope of EGFR binding to adnectin

scientific article published on 30 September 2014

HD exchange and PLIMSTEX determine the affinities and order of binding of Ca2+ with troponin C.

scientific article published on 26 May 2011

Higher order structure characterization of protein therapeutics by hydrogen/deuterium exchange mass spectrometry.

scientific article

Higher-Order Structure Characterization of NKG2A/CD94 Protein Complex and Anti-NKG2A Antibody Binding Epitopes by Mass Spectrometry-Based Protein Footprinting Strategies

scientific article published on 08 January 2021

Hydrogen-deuterium exchange mass spectrometry reveals the interaction of Fenna-Matthews-Olson protein and chlorosome CsmA protein

scientific article published on 9 December 2011

Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization

scientific article

Hydrogen/deuterium exchange mass spectrometry and computational modeling reveal a discontinuous epitope of an antibody/TL1A Interaction

scientific article published on 14 November 2017

Hydrogen/deuterium exchange mass spectrometry applied to IL-23 interaction characteristics: potential impact for therapeutics

scientific article

Hydrophobic Peptides Affect Binding of Calmodulin and Ca as Explored by H/D Amide Exchange and Mass Spectrometry.

scientific article

Identification of CaMKII phosphorylation sites in Connexin43 by high-resolution mass spectrometry.

scientific article

Improved mass spectrometric characterization of protein glycosylation reveals unusual glycosylation of maize-derived bovine trypsin.

scientific article

Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb

scientific article published on 14 May 2019

Mapping binding epitopes of monoclonal antibodies targeting major histocompatibility complex class I chain-related A (MICA) with hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry

scientific article published on 29 January 2020

Mapping the Energetic Epitope of an Antibody/Interleukin-23 Interaction with Hydrogen/Deuterium Exchange, Fast Photochemical Oxidation of Proteins Mass Spectrometry, and Alanine Shave Mutagenesis.

scientific article published on 9 February 2017

Mass spectrometry assessment of ubiquitin carboxyl-terminal hydrolase L1 partitioning between soluble and particulate brain homogenate fractions

scientific article

Mass spectrometry-based carboxyl footprinting of proteins: method evaluation.

scientific article

Mass spectrometry-based footprinting reveals structural dynamics of loop E of the chlorophyll-binding protein CP43 during photosystem II assembly in the cyanobacterium Synechocystis 6803.

scientific article published on April 2013

Molecular perspective of antibody aggregates and their adsorption on Protein A resin

scientific article published on 11 June 2016

Orthogonal Mass Spectrometry-Based Footprinting for Epitope Mapping and Structural Characterization: The IL-6 Receptor upon Binding of Protein Therapeutics

scientific article published on 16 June 2017

Probing Conformational Dynamics of Tau Protein by Hydrogen/Deuterium Exchange Mass Spectrometry

scientific article published on 2 October 2017

Psb27, a transiently associated protein, binds to the chlorophyll binding protein CP43 in photosystem II assembly intermediates ⬇️

scientific article published on October 26, 2011

Radiosynthesis and preclinical PET evaluation of 89Zr-nivolumab (BMS-936558) in healthy non-human primates

scientific article published on 4 August 2017

Residual Cx45 and its relationship to Cx43 in murine ventricular myocardium ⬇️

scientific article published on November 1, 2011

Site-Selective Functionalization of Methionine Residues via Photoredox Catalysis

scientific article published on 08 December 2020

Site-selective tyrosine bioconjugation via photoredox catalysis for native-to-bioorthogonal protein transformation

scientific article published in 2021

Site-selective, cleavable linkers: quality control and the characterization of small molecules on microelectrode arrays

scientific article published on 10 October 2011

Slow Off-Rate Modified Aptamer (SOMAmer) as a Novel Reagent in Immunoassay Development for Accurate Soluble Glypican-3 Quantification in Clinical Samples

scientific article published on 06 April 2018

Structure of the human marker of self 5-transmembrane receptor CD47

scientific article published on 01 September 2021

Utility of Ion Mobility Mass Spectrometry for Drug-to-Antibody Ratio Measurements in Antibody-Drug Conjugates

scientific article published on 30 June 2015

VISTA is an acidic pH-selective ligand for PSGL-1

scientific article published on 23 October 2019

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