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List of works by Lucinda J. Billingham

A Practical Application of Value of Information and Prospective Payback of Research to Prioritize Evaluative Research.

scientific article

Abdominal resection rectopexy with pelvic floor repair versus perineal rectosigmoidectomy and pelvic floor repair for full-thickness rectal prolapse

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Addressing overtreatment of screen detected DCIS; the LORIS trial

scientific article published on 18 August 2015

Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers

scientific article

An open letter to all members of the IASLC

scientific article published on 01 July 2004

Analysis of phase II methodologies for single-arm clinical trials with multiple endpoints in rare cancers: An example in Ewing's sarcoma

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Antibacterial prophylaxis after chemotherapy for solid tumors and lymphomas

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Assessment of high-throughput high-resolution MALDI-TOF-MS of urinary peptides for the detection of muscle-invasive bladder cancer.

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Can we afford to ignore missing data in cost-effectiveness analyses?

scientific article published in February 2009

Carboplatin versus two doses of cisplatin in combination with gemcitabine in the treatment of advanced non-small-cell lung cancer: Results from a British Thoracic Oncology Group randomised phase III trial

scientific article

Changes in the serum proteome associated with the development of hepatocellular carcinoma in hepatitis C-related cirrhosis

scientific article published on January 2006

Choice of transformation for modelling non-linear continuous biomarkers

scientific article published on 13 December 2011

Clinical development of new drug-radiotherapy combinations ⬇️

scientific article published on June 2016

Clinical trial design in hepatocellular carcinoma.

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Clinical trial designs for rare diseases: studies developed and discussed by the International Rare Cancers Initiative ⬇️

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Colony counting is a major source of variation in CFU-GM results between centres

scientific article published on 01 May 1997

Confusion Over Differences in Registration and Randomization Criteria for the LORIS (Low-Risk DCIS) Trial

scientific article published on 28 November 2017

Cost-effectiveness in clinical trials: using multiple imputation to deal with incomplete cost data

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Cost-effectiveness of cardiac resynchronization therapy: results from the CARE-HF trial.

scientific article published on 11 November 2005

Crossing survival curves: alternatives to the log-rank test

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Do the methods used to analyse missing data really matter? An examination of data from an observational study of Intermediate Care patients

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Does palpability of primary cutaneous melanoma predict dermal invasion?

scientific article published on April 1996

Dose Transition Pathways: The Missing Link Between Complex Dose-Finding Designs and Simple Decision-Making

scientific article published on 21 July 2017

Dose transition pathways: a design, analysis and operational tool for dose-finding trials using model-based designs.

scientific article

Early radiotherapy related morbidity

scientific article published on 01 July 2003

Effect of Epstein-Barr virus infection on response to chemotherapy and survival in Hodgkin's disease.

scientific article published in July 1999

Effect of topical imiquimod as primary treatment for lentigo maligna: the LIMIT-1 study

scientific article published on 10 April 2017

Effective delivery of Complex Innovative Design (CID) cancer trials-A consensus statement

scientific article published on 06 January 2020

Estimating the cost-effectiveness of an intervention in a clinical trial when partial cost information is available: a Bayesian approach

scientific article published in January 2008

Estrogen receptor and progesterone receptor as predictive biomarkers of response to endocrine therapy: a prospectively powered pathology study in the Tamoxifen and Exemestane Adjuvant Multinational trial

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European trial of free light chain removal by extended haemodialysis in cast nephropathy (EuLITE): a randomised control trial.

scientific article published on 28 September 2008

Evaluation of methods to adjust for treatment switching in clinical trials

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Excision Repair Cross-Complementation Group 1 (ERCC1) Status and Lung Cancer Outcomes: A Meta-Analysis of Published Studies and Recommendations ⬇️

scientific article published on October 14, 2011

Expression of E-cadherin in oesophageal carcinomas from the UK and China: disparities in prognostic significance ⬇️

scientific article published on August 1, 1997

Expression of p53 protein in oesophageal carcinoma: clinicopathological correlation and prognostic significance

scientific article published on 01 November 1994

Follow up after Primary Treatment of Soft Tissue Sarcoma: A Survey of Current Practice in the United Kingdom

scientific article

Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers

scientific article published on 19 July 2011

Health-related quality of life around the time of diagnosis in patients with bladder cancer

scientific article published on 07 June 2019

High lactate dehydrogenase level is associated with an adverse outlook in autografting for Hodgkin's disease

scientific article published on 01 March 1996

Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer.

scientific article published on January 2007

Implementing the EffTox dose-finding design in the Matchpoint trial.

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Influence of ethnic origin on the pattern of congenital heart defects in the first year of life.

scientific article published on February 1995

Interleukin 6 expression by Hodgkin/Reed-Sternberg cells is associated with the presence of 'B' symptoms and failure to achieve complete remission in patients with advanced Hodgkin's disease

scientific article published on 01 July 2002

Management of febrile neutropenia in the United Kingdom: time for a national trial?

scientific article published on December 2005

Management preferences in stage I non-seminomatous germ cell tumours of the testis: an investigation among patients, controls and oncologists

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Mapping utility scores from the Barthel index.

scientific article published on 2 November 2011

Meta-analysis of randomized phase II trials to inform subsequent phase III decisions

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Methodological Considerations in the Evaluation of Radiotherapy Technologies

scientific article published on 12 July 2012

Mitomycin, ifosfamide, and cisplatin in unresectable non-small-cell lung cancer: effects on survival and quality of life

scientific article published in October 1999

Multiple testing issues in discriminating compound-related peaks and chromatograms from high frequency noise, spikes and solvent-based noise in LC-MS data sets.

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Narrow-band imaging flexible cystoscopy in the detection of recurrent urothelial cancer of the bladder.

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Patient preferences for clinical follow-up after primary treatment for soft tissue sarcoma: a cross-sectional survey and discrete choice experiment

scientific article published on 26 June 2014

Patients choose certainty over burden in bladder cancer surveillance

scientific article published on 23 March 2019

Patterns, costs and cost-effectiveness of care in a trial of chemotherapy for advanced non-small cell lung cancer

scientific article

Pembrolizumab in patients with non-small-cell lung cancer of performance status 2 (PePS2): a single arm, phase 2 trial

scientific article published on 19 March 2020

Phase I/II trial of a dendritic cell vaccine transfected with DNA encoding melan A and gp100 for patients with metastatic melanoma.

scientific article published on 10 February 2011

Plasma proteome analysis reveals the geographical origin and liver tumor status of Dab (Limanda limanda) from UK marine waters

scientific article

Podophyllin 0.5% or 2.0% v podophyllotoxin 0.5% for the self treatment of penile warts: a double blind randomised study.

scientific article

Poor prognosis and limited therapeutic options in patients with Budd-Chiari syndrome and portal venous system thrombosis

scientific article published in May 1997

Potential hazards in the analysis of symptom improvement

scientific article published in May 2003

Problems of variable biomarker evaluation in stratified medicine research--A case study of ERCC1 in non-small-cell lung cancer

scientific article

Quality assurance of CFU-GM assays: inter-laboratory variation despite standard reagents

scientific article published on 01 January 1999

Quality of life in non-small-cell lung cancer

scientific article published on 01 April 2000

Radiotherapy Research Priorities for the UK

scientific article published on 02 April 2010

Randomized trial to determine the optimum level of pouch-anal anastomosis in stapled restorative proctocolectomy

scientific article published on 01 February 1995

Rational selection of patients for antibacterial prophylaxis after chemotherapy

scientific article

Research methods to change clinical practice for patients with rare cancers.

scientific article published on February 2016

Retrospective study of acute toxicity following short-course preoperative radiotherapy

scientific article published on 01 July 2002

Reviewing the evidence supporting predictive biomarkers in European medicines agency indications and contraindications using visual plots.

scientific article published on 16 November 2015

Sample size calculations for designing clinical proteomic profiling studies using mass spectrometry

scientific article published on 10 February 2012

Sample size determination in clinical proteomic profiling experiments using mass spectrometry for class comparison

scientific article published in January 2009

Screened selection design for randomised phase II oncology trials: an example in chronic lymphocytic leukaemia

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Screened selection design for randomised phase II oncology trials: an example in chronic lymphocytic leukaemia

Simultaneous analysis of quality of life and survival data.

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Smoking is associated with lower age, higher grade, higher stage, and larger size of malignant bladder tumors at diagnosis

scientific article published on 13 February 2013

Sorafenib for liver cancer: the horizon broadens

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Stratified medicine in European Medicines Agency licensing: a systematic review of predictive biomarkers

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Stratified medicine in practice: review of predictive biomarkers in European Medicines Agency (EMA) indications.

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TRAPEZE: a randomised controlled trial of the clinical effectiveness and cost-effectiveness of chemotherapy with zoledronic acid, strontium-89, or both, in men with bony metastatic castration-refractory prostate cancer

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The National Lung Matrix Trial: translating the biology of stratification in advanced non-small-cell lung cancer

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The West Midlands Bladder Cancer Prognosis Programme: rationale and design.

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The benefits of chemotherapy in patient subgroups with unresectable non-small-cell lung cancer

scientific article published in December 2001

The effect of Epstein-Barr virus status on outcome in age- and sex-defined subgroups of patients with advanced Hodgkin's disease.

scientific article published in February 2003

The effect of directed biopsy on the atypical cervical transformation zone: assessed by digital imaging colposcopy.

scientific article

The effect of head and neck irradiation on taste dysfunction: a prospective study

scientific article published on 01 January 1995

The effects of gemcitabine and capecitabine combination chemotherapy and of low-dose adjuvant GM-CSF on the levels of myeloid-derived suppressor cells in patients with advanced pancreatic cancer.

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The hypoxia marker CAIX is prognostic in the UK phase III VorteX-Biobank cohort: an important resource for translational research in soft tissue sarcoma.

scientific article published on 12 December 2017

The number of cytomegalovirus-specific CD4+ T cells is markedly expanded in patients with B-cell chronic lymphocytic leukemia and determines the total CD4+ T-cell repertoire

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Trials in rare diseases: the need to think differently.

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Tumour heterogeneity: a problem in biopsy assessment of the proliferation index of oesophageal adenocarcinomas.

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Using meta-analysis of Phase II trials to predict Phase III trial results

scientific article published on 29 November 2013

Warfarin thromboprophylaxis in cancer patients with central venous catheters (WARP): an open-label randomised trial

scientific article published in February 2009

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