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List of works by Nazareno Paolocci

Acyloxy nitroso compounds inhibit LIF signaling in endothelial cells and cardiac myocytes: evidence that STAT3 signaling is redox-sensitive

scientific article

Apolipoprotein A-I mimetic peptide L-4F prevents myocardial and coronary dysfunction in diabetic mice

scientific article

CCR5 inhibition prevents cardiac dysfunction in the SIV/macaque model of HIV.

scientific article published on 2 April 2014

Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure

scientific article published on 9 December 2004

Cardiac phosphodiesterase 5 (cGMP-specific) modulates beta-adrenergic signaling in vivo and is down-regulated in heart failure

scientific article

Cardioprotective effect of beta-3 adrenergic receptor agonism: role of neuronal nitric oxide synthase

scientific article

Changes in plasma level of human leukocyte elastase during leukocytosis from physical effort

scientific article published on August 2003

Cholinergic neurons of mouse intrinsic cardiac ganglia contain noradrenergic enzymes, norepinephrine transporters, and the neurotrophin receptors tropomyosin-related kinase A and p75.

scientific article published on 08 July 2008

Cobalt-Protoporphyrin Improves Heart Function by Blunting Oxidative Stress and Restoring NO Synthase Equilibrium in an Animal Model of Experimental Diabetes

scientific article

Cofilin-2 phosphorylation and sequestration in myocardial aggregates: novel pathogenetic mechanisms for idiopathic dilated cardiomyopathy

scientific article

Collaterals of recurrent laryngeal nerve fibres innervate the thymus: a fluorescent tracer and HRP investigation of efferent vagal neurons in the rat brainstem

scientific article published in November 1998

Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo

scientific article published in December 2005

Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins. A chemical discussion of the differential biological effects of these redox related products of NOS.

scientific article published in January 2003

Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway

scientific article published on 15 December 2005

Constitutive BDNF/TrkB signaling is required for normal cardiac contraction and relaxation.

scientific article

Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved.

scientific article published on 27 December 2011

Cytochrome P-450 metabolite of arachidonic acid mediates bradykinin-induced negative inotropic effect.

scientific article

Depletion of cellular glutathione modulates LIF-induced JAK1-STAT3 signaling in cardiac myocytes ⬇️

scientific article published on August 22, 2012

Detection of hydroxyl radicals by D-phenylalanine hydroxylation: a specific assay for hydroxyl radical generation in biological systems.

scientific article

Differential effects of pulsatile versus steady flow on coronary endothelial membrane potential

scientific article

Discriminating formation of HNO from other reactive nitrogen oxide species

scientific article published on 21 November 2005

Effects of cardioselective KATP channel antagonism on basal, stimulated, and ischaemic myocardial function in in vivo failing canine heart. ⬇️

scientific article

Endocardial endothelium is a key determinant of force-frequency relationship in rat ventricular myocardium

scientific article published on 23 May 2013

Endothelin-1 and NO2/NO3 circulating levels after short-term (1h) oxygen supplementation in patients with chronic respiratory failure during long-term oxygen treatment (LTOT)

scientific article published on 01 August 1998

ErbB2 overexpression upregulates antioxidant enzymes, reduces basal levels of reactive oxygen species, and protects against doxorubicin cardiotoxicity.

scientific article

Forever young?: nerve growth factor, sympathetic fibers, and right ventricle pressure overload

scientific article published on 01 June 2007

From metabolomics to fluxomics: a computational procedure to translate metabolite profiles into metabolic fluxes

scientific article

Functional gut disorders and health care seeking behavior in an Italian non-patient population

scientific article published on 01 May 1989

GSH or palmitate preserves mitochondrial energetic/redox balance, preventing mechanical dysfunction in metabolically challenged myocytes/hearts from type 2 diabetic mice

scientific article

Genes, geography and geometry: the "critical mass" in hypertrophic cardiomyopathy

scientific article published on 4 December 2008

Glutathione oxidation unmasks proarrhythmic vulnerability of chronically hyperglycemic guinea pigs

scientific article published on February 2013

Guide for the use of nitric oxide (NO) donors as probes of the chemistry of NO and related redox species in biological systems

scientific article published on 01 January 2002

High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury

scientific article published on 24 March 2008

Hydrogen sulfide [corrected] increases survival during sepsis: protective effect of CHOP inhibition

scientific article published on 08 January 2014

Hypothermia triggers iron-dependent lipoperoxidative damage in the isolated rat heart

scientific article published on 01 April 1994

Immunopathological mechanisms underlying the time-course of Trichinella spiralis cardiomyopathy in rats

scientific article published on 01 March 1998

Impaired mitochondrial energy supply coupled to increased H2O2 emission under energy/redox stress leads to myocardial dysfunction during Type I diabetes.

scientific article

Improved mechanoenergetics and cardiac rest and reserve function of in vivo failing heart by calcium sensitizer EMD-57033

scientific article published on 01 March 2000

In utero partial liver resection in the rabbit model: a study on fetal tissue regeneration.

scientific article published in July 1997

Inhibiting metalloproteases with PD 166793 in heart failure: impact on cardiac remodeling and beyond.

scientific article published on January 2008

Lymphocyte traffic changes induced by monolateral vagal denervation in mouse thymus and peripheral lymphoid organs

scientific article published on 01 February 1996

Mechanism of aerobic decomposition of Angeli's salt (sodium trioxodinitrate) at physiological pH

scientific article published on 01 January 2005

Metalloproteinase inhibitor counters high-energy phosphate depletion and AMP deaminase activity enhancing ventricular diastolic compliance in subacute heart failure

scientific article published on 25 January 2006

Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload

scientific article

Monoamine oxidase B prompts mitochondrial and cardiac dysfunction in pressure overloaded hearts

scientific article

Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury

scientific article

Monoamine oxidases as sources of oxidants in the heart

scientific article

Morphometric analysis of smooth muscle in the exstrophy-epispadias complex

scientific article published on 01 August 1996

Mother was right: eat your vegetables and do not spit! When oral nitrate helps with high blood pressure

scientific article published on 04 February 2008

New redox-related arrows in the arsenal of cardiac disease treatment.

scientific article

Nitroxyl (HNO): A novel approach for the acute treatment of heart failure

scientific article

Nitroxyl affords thiol-sensitive myocardial protective effects akin to early preconditioning.

scientific article

Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.

scientific article

Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling

scientific article

Nitroxyl increases force development in rat cardiac muscle

scientific article published on 01 March 2007

Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function.

scientific article

Novel regulation of cardiac force-frequency relation by CREM (cAMP response element modulator)

scientific article (publication date: February 2003)

Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm.

scientific article

Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load

scientific article

Oxygen radical-mediated reduction in basal and agonist-evoked NO release in isolated rat heart

scientific article

Peroxynitrite and myocardial contractility: in vivo versus in vitro effects

scientific article published on 05 September 2006

Peroxynitrite like Pan?

scientific article published in August 2005

Phospholamban thiols play a central role in activation of the cardiac muscle sarcoplasmic reticulum calcium pump by nitroxyl

scientific article published in December 2008

Positive inotropic and lusitropic effects of HNO/NO − in failing hearts: Independence from β-adrenergic signaling ⬇️

scientific article published on April 18, 2003

Protective mechanisms of mitochondria and heart function in diabetes

scientific article

Removal of Abnormal Myofilament O-GlcNAcylation Restores Ca2+ Sensitivity in Diabetic Cardiac Muscle.

scientific article

Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy

scientific article published on 12 May 2008

Reversal of glibenclamide-induced coronary vasoconstriction by enhanced perfusion pulsatility: possible role for nitric oxide

scientific article published on 01 March 2000

Reversal of isoflurane-induced depression of myocardial contraction by nitroxyl via myofilament sensitization to Ca2+

scientific article published on 24 August 2011

Reverse remodeling and enhanced adrenergic reserve from passive external support in experimental dilated heart failure

scientific article published in June 2002

Role of calcitonin gene-related peptide (CGRP) in chronic hypoxia-induced pulmonary hypertension in the mouse. Influence of gene transfer in vivo

scientific article published in October 2002

Role of calcium-sensitive K(+) channels and nitric oxide in in vivo coronary vasodilation from enhanced perfusion pulsatility.

scientific article

Sexual dimorphism in cardiac norepinephrine spillover: a NET difference

scientific article published on 09 December 2010

Soluble guanylate cyclase is required for systemic vasodilation but not positive inotropy induced by nitroxyl in the mouse.

scientific article

Specificity of synergistic coronary flow enhancement by adenosine and pulsatile perfusion in the dog

scientific article published on 01 October 1999

Synthesis and chemical and biological comparison of nitroxyl- and nitric oxide-releasing diazeniumdiolate-based aspirin derivatives

scientific article published on 08 October 2013

The chemical dynamics of NO and reactive nitrogen oxides: a practical guide.

scientific article

The emergence of nitroxyl (HNO) as a pharmacological agent.

scientific article published on 06 May 2009

The p75 neurotrophin receptor, semaphorins, and sympathetic traffic in the heart

scientific article published on 19 March 2010

The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO

scientific article

The shy Angeli and his elusive creature: the HNO route to vasodilation

scientific article published on 13 March 2009

The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems.

scientific article

Thioredoxin reductase-2 is essential for keeping low levels of H(2)O(2) emission from isolated heart mitochondria

scientific article

Vagal control of lymphocyte release from rat thymus.

scientific article

Warburg effect's manifestation in aggressive pheochromocytomas and paragangliomas: insights from a mouse cell model applied to human tumor tissue

scientific article

When the heart sleeps... is the vagus resetting the myocardial 'redox clock'?

scientific article published on 14 January 2008

[Hepatic resection in the fetal rabbit. Histologic comparison of tissue regeneration in the fetus versus the adult]

scientific article published on 01 November 1996

beta-blockade prevents sustained metalloproteinase activation and diastolic stiffening induced by angiotensin II combined with evolving cardiac dysfunction

scientific article published on 01 April 2000

cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation

scientific article published on 01 October 2000

β₂-Adrenoceptors, NADPH oxidase, ROS and p38 MAPK: another 'radical' road to heart failure?

scientific article published on March 2011

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