List of works - Yannis Kalaidzidis

A Global Approach for Quantitative Super Resolution and Electron Microscopy on Cryo and Epoxy Sections Using Self-labeling Protein Tags

scientific article

A Spatial Model of Insulin-Granule Dynamics in Pancreatic β-Cells

scientific article published on May 2015

A drug discovery platform to identify compounds that inhibit EGFR triple mutants

scientific article published on 24 February 2020

A general theoretical framework to infer endosomal network dynamics from quantitative image analysis

scientific article

A method for validation for clustering of phenotypic gene knockdown profiles using protein-protein interactions information.

scientific article published on 19 October 2009

A segmentation method to obtain a complete geometry model of the hearing organ

scientific article published on 18 July 2011

A versatile pipeline for the multi-scale digital reconstruction and quantitative analysis of 3D tissue architecture

scientific article

APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments

scientific article

Age-dependent labeling and imaging of insulin secretory granules

scientific article published on 8 August 2013

Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies

scientific article

An endosomal tether undergoes an entropic collapse to bring vesicles together

scientific article

Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads

scientific article published in 2021

Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment

scientific article published on 3 July 2011

Control of convergent yolk syncytial layer nuclear movement in zebrafish.

scientific article published on 11 March 2009

Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen

scientific article published on 30 January 2014

Development of a Kinetic Assay for Late Endosome Movement

scientific article published on 20 February 2014

Domain-specific model selection for structural identification of the Rab5-Rab7 dynamics in endocytosis

scientific article published on 26 June 2015

Dynamin inhibitors impair endocytosis and mitogenic signaling of PDGF.

scientific article published on 12 March 2013

Erratum: Corrigendum: Systems survey of endocytosis by multiparametric image analysis

scientific article published in Nature

Forebrain-specific loss of synaptic GABAA receptors results in altered neuronal excitability and synaptic plasticity in mice.

scientific article published on 29 January 2016

Functional properties of hepatocytes in vitro are correlated with cell polarity maintenance

scientific article published on December 2016

Identification of siRNA delivery enhancers by a chemical library screen

scientific article published on 28 July 2015

Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape

scientific article published on 23 June 2013

Integration of chemical and RNAi multiparametric profiles identifies triggers of intracellular mycobacterial killing

scientific article

Intracellular objects tracking

scientific article published on 23 July 2007

Kinetics of morphogen gradient formation.

scientific article published in January 2007

Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations

scientific article

Membrane identity and GTPase cascades regulated by toggle and cut-out switches

scientific article

Multiple objects tracking in fluorescence microscopy

scientific article

Multiple routes of endocytic internalization of PDGFRβ contribute to PDGF-induced STAT3 signaling

scientific article published on 15 December 2016

Nucleocytoplasmic shuttling of the Golgi phosphatidylinositol 4-kinase Pik1 is regulated by 14-3-3 proteins and coordinates Golgi function with cell growth

scientific article published on 2 January 2008

Objective comparison of particle tracking methods

scientific article

Protein Domains of GTPases on Membranes: Do They Rely on Turing’s Mechanism?

Quantification of nematic cell polarity in three-dimensional tissues

scientific article published on 10 December 2020

Rab conversion as a mechanism of progression from early to late endosomes

scientific article (publication date: 9 September 2005)

Rab5 is necessary for the biogenesis of the endolysosomal system in vivo

scientific article published on 23 May 2012

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.

scientific article

Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment

scientific article published on 19 February 2011

Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes.

scientific article published on 4 February 2015

Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6

scientific article

Regulation of insulin granule turnover in pancreatic beta-cells by cleaved ICA512.

scientific article

Resilience of three-dimensional sinusoidal networks in liver tissue

scientific article published on 29 June 2020

Retrograde transport of Akt by a neuronal Rab5-APPL1 endosome

article published in 2019

Revealing molecular mechanisms by integrating high-dimensional functional screens with protein interaction data

scientific article

RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase

scientific article

SNX27-retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis

scientific article published on 01 January 2020

Signal processing by the endosomal system

scientific article

Systems survey of endocytosis by multiparametric image analysis.

scientific article published on 28 February 2010

The clathrin adaptor Gga2p is a phosphatidylinositol 4-phosphate effector at the Golgi exit

scientific article

The creation of geometric three-dimensional models of the inner ear based on micro computer tomography data

scientific article

The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends

scientific article (publication date: 4 May 2006)

siRNA screening reveals JNK2 as an evolutionary conserved regulator of triglyceride homeostasis

scientific article published on 08 July 2008

β2-Syntrophin is a Cdk5 substrate that restrains the motility of insulin secretory granules

scientific article

List of works by Yannis Kalaidzidis

A Global Approach for Quantitative Super Resolution and Electron Microscopy on Cryo and Epoxy Sections Using Self-labeling Protein Tags

A Spatial Model of Insulin-Granule Dynamics in Pancreatic β-Cells

A drug discovery platform to identify compounds that inhibit EGFR triple mutants

A general theoretical framework to infer endosomal network dynamics from quantitative image analysis

A method for validation for clustering of phenotypic gene knockdown profiles using protein-protein interactions information.

A segmentation method to obtain a complete geometry model of the hearing organ

A versatile pipeline for the multi-scale digital reconstruction and quantitative analysis of 3D tissue architecture

APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments

Age-dependent labeling and imaging of insulin secretory granules

Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies

An endosomal tether undergoes an entropic collapse to bring vesicles together

Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads

Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment

Control of convergent yolk syncytial layer nuclear movement in zebrafish.

Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen

Development of a Kinetic Assay for Late Endosome Movement

Domain-specific model selection for structural identification of the Rab5-Rab7 dynamics in endocytosis

Dynamin inhibitors impair endocytosis and mitogenic signaling of PDGF.

Erratum: Corrigendum: Systems survey of endocytosis by multiparametric image analysis

Forebrain-specific loss of synaptic GABAA receptors results in altered neuronal excitability and synaptic plasticity in mice.

Functional properties of hepatocytes in vitro are correlated with cell polarity maintenance

Identification of siRNA delivery enhancers by a chemical library screen

Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape

Integration of chemical and RNAi multiparametric profiles identifies triggers of intracellular mycobacterial killing

Intracellular objects tracking

Kinetics of morphogen gradient formation.

Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations

Membrane identity and GTPase cascades regulated by toggle and cut-out switches

Multiple objects tracking in fluorescence microscopy

Multiple routes of endocytic internalization of PDGFRβ contribute to PDGF-induced STAT3 signaling

Nucleocytoplasmic shuttling of the Golgi phosphatidylinositol 4-kinase Pik1 is regulated by 14-3-3 proteins and coordinates Golgi function with cell growth

Objective comparison of particle tracking methods

Protein Domains of GTPases on Membranes: Do They Rely on Turing’s Mechanism?

Quantification of nematic cell polarity in three-dimensional tissues

Rab conversion as a mechanism of progression from early to late endosomes

Rab5 is necessary for the biogenesis of the endolysosomal system in vivo

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.

Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment

Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes.

Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6

Regulation of insulin granule turnover in pancreatic beta-cells by cleaved ICA512.

Resilience of three-dimensional sinusoidal networks in liver tissue

Retrograde transport of Akt by a neuronal Rab5-APPL1 endosome

Revealing molecular mechanisms by integrating high-dimensional functional screens with protein interaction data

RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase

SNX27-retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis

Signal processing by the endosomal system

Systems survey of endocytosis by multiparametric image analysis.

The clathrin adaptor Gga2p is a phosphatidylinositol 4-phosphate effector at the Golgi exit

The creation of geometric three-dimensional models of the inner ear based on micro computer tomography data

The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends

siRNA screening reveals JNK2 as an evolutionary conserved regulator of triglyceride homeostasis

β2-Syntrophin is a Cdk5 substrate that restrains the motility of insulin secretory granules