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List of works by Itai Benhar

"Inclonals": IgGs and IgG-enzyme fusion proteins produced in an E. coli expression-refolding system

scientific article published on 19 May 2009

A Simple and Rapid Method for Preparing a Cell-Free Bacterial Lysate for Protein Synthesis.

scientific article

A human synthetic combinatorial library of arrayable single-chain antibodies based on shuffling in vivo formed CDRs into general framework regions.

scientific article

A key role for IL-13 signaling via the type 2 IL-4 receptor in experimental atopic dermatitis

scientific article published on 01 February 2020

A method for purifying high quality and high yield plasmid DNA for metagenomic and deep sequencing approaches.

scientific article

A novel high throughput screening assay for HCV NS3 serine protease inhibitors

scientific article published in February 2003

A novel magnetic beads-based method for polioviral concentration from environmental samples

scientific article published on 09 July 2018

A two-state electronic antigen and an antibody selected to discriminate between these states

scientific article

A universal strategy for stable intracellular antibodies

scientific article published in August 2005

Administration of disulfide-stabilized Fv-immunotoxins B1(dsFv)-PE38 and B3(dsFv)-PE38 by continuous infusion increases their efficacy in curing large tumor xenografts in nude mice

scientific article published on 01 July 1995

An immunoconjugate of anti-CD24 and Pseudomonas exotoxin selectively kills human colorectal tumors in mice

scientific article published on 11 December 2010

An internalizing antibody specific for the human asialoglycoprotein receptor

scientific article published in August 2009

An investigation of antistreptococcal antibody responses in guttate psoriasis

article

Annexin A2, autoimmunity, anxiety and depression

scientific article published on 29 June 2016

Antibacterial application of engineered bacteriophage nanomedicines: antibody-targeted, chloramphenicol prodrug loaded bacteriophages for inhibiting the growth of Staphylococcus aureus bacteria

scientific article published in January 2011

Antibacterial nanomedicine.

scientific article published on June 2008

Antibody Targeting of Cell-Bound MUC1 SEA Domain Kills Tumor Cells

scientific article published on April 16, 2012

Antibody internalization studied using a novel IgG binding toxin fusion

scientific article

Antibody isolation from immunized animals: comparison of phage display and antibody discovery via V gene repertoire mining

scientific article

Antibody molecules discriminate between crystalline facets of a gallium arsenide semiconductor.

scientific article

Antibody-targeted drugs and drug resistance--challenges and solutions.

scientific article

Behavioral and neural effects of intra-striatal infusion of anti-streptococcal antibodies in rats

scientific article published on 20 February 2014

Behavioral, pharmacological, and immunological abnormalities after streptococcal exposure: a novel rat model of Sydenham chorea and related neuropsychiatric disorders.

scientific article

Biotechnological applications of phage and cell display

scientific article (publication date: February 2001)

Characterization of B1(Fv)PE38 and B1(dsFv)PE38: single-chain and disulfide-stabilized Fv immunotoxins with increased activity that cause complete remissions of established human carcinoma xenografts in nude mice.

scientific article

Cloning, expression and characterization of the Fv fragments of the anti-carbohydrate mAbs B1 and B5 as single-chain immunotoxins

scientific article published on 01 December 1994

Cross-immunogenicity: antibodies to infliximab in Remicade-treated patients with IBD similarly recognise the biosimilar Remsima

scientific article published on 20 April 2015

Cross-reactivity between annexin A2 and Beta-2-glycoprotein I in animal models of antiphospholipid syndrome

scientific article published on 23 July 2016

Crystal structure of the disulfide-stabilized Fv fragment of anticancer antibody B1: Conformational influence of an engineered disulfide bond

scientific article published on May 1, 1998

Cytotoxic and antitumor activity of a recombinant tumor necrosis factor-B1(Fv) fusion protein on LeY antigen-expressing human cancer cells

scientific article published on 01 September 1996

Design Principles for Bispecific IgGs, Opportunities and Pitfalls of Artificial Disulfide Bonds

scientific article published on 28 July 2018

Design of a human synthetic combinatorial library of single-chain antibodies

scientific article

Design of synthetic antibody libraries

scientific article

Disruption of P-glycoprotein anticancer drug efflux activity by a small recombinant single-chain Fv antibody fragment targeted to an extracellular epitope.

scientific article published on May 2004

Duality of serotonin-N-acetyltransferase in the gilthead seabream (Sparus aurata): molecular cloning and characterization of recombinant enzymes

scientific article

Electrically controlled molecular recognition harnessed to activate a cellular response

scientific article published on 21 October 2011

Engineered B cells expressing an anti-HIV antibody enable memory retention, isotype switching and clonal expansion

scientific article published on 17 November 2020

Engineered toxins "zymoxins" are activated by the HCV NS3 protease by removal of an inhibitory protein domain

scientific article

Escherichia coli maltose-binding protein as a molecular chaperone for recombinant intracellular cytoplasmic single-chain antibodies.

scientific article

Fluorescent IgG fusion proteins made in E. coli

scientific article published on 26 April 2012

Frameshifting in the expression of the E. coli trpR gene occurs by the bypassing of a segment of its coding sequence

scientific article published on 01 January 1993

Frameshifting in the expression of the Escherichia coli trpR gene

scientific article published on October 1992

Frameshifting in the expression of the Escherichia coli trpR gene is modulated by translation initiation.

scientific article

Humanization and epitope mapping of the H23 anti-MUC1 monoclonal antibody reveals a dual epitope specificity

scientific article published in January 2005

Identification and characterization of a novel molecular-recognition and self-assembly domain within the islet amyloid polypeptide

scientific article published on 01 October 2002

Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A.

scientific article

Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3.

scientific article

In vivo characteristics of targeted drug-carrying filamentous bacteriophage nanomedicines

scientific article published on 20 December 2011

Inhibition of hepatitis C virus NS3-mediated cell transformation by recombinant intracellular antibodies

scientific article published on June 2004

Inhibition of protease-inhibitor-resistant hepatitis C virus replicons and infectious virus by intracellular intrabodies.

scientific article published on 10 August 2010

Insights into the bovine rumen plasmidome

scientific article

Isolating EGFR Overexpressing Carcinoma Cells from Human Whole Blood by Bio-Ferrography

scientific article published on 28 November 2014

Isolating epidermal growth factor receptor overexpressing carcinoma cells from human whole blood by bio-ferrography

scientific article published on 10 December 2014

Isolation of scFvs that inhibit the NS3 protease of hepatitis C virus by a combination of phage display and a bacterial genetic screen

scientific article published in January 2009

Killing cancer cells by targeted drug-carrying phage nanomedicines

scientific article

Large scale production of recombinant antibodies by utilizing cellulose-binding domains

scientific article published on 01 January 2003

MUC1/X protein immunization enhances cDNA immunization in generating anti-MUC1 alpha/beta junction antibodies that target malignant cells.

scientific article published on December 2006

Magnetic isolation of particles suspended in synovial fluid for diagnostics of natural joint chondropathies.

scientific article published on 8 June 2010

Maltose-binding protein enhances secretion of recombinant human granzyme B accompanied by in vivo processing of a precursor MBP fusion protein

scientific article

Matrix-Assisted Refolding of Single-Chain Fv– Cellulose Binding Domain Fusion Proteins

scientific article published on 01 November 1999

Mechanical properties of Bio-Ferrography isolated cancerous cells studied by atomic force microscopy

scientific article published on 31 December 2018

Minimum information about a protein affinity reagent (MIAPAR)

scientific article published on 01 July 2010

Modulation of Alzheimer's beta-amyloid neurotoxicity by site-directed single-chain antibody.

scientific article published in July 2000

Mutations of two lysine residues in the CDR loops of a recombinant immunotoxin that reduce its sensitivity to chemical derivatization.

scientific article

Novel Water-Soluble Amphotericin B-PEG Conjugates with Low Toxicity and Potent in Vivo Efficacy.

scientific article published on 27 January 2016

Novel immune check point inhibiting antibodies in cancer therapy-Opportunities and challenges

scientific article published in January 2017

On the limited recognition of inorganic surfaces by short peptides compared with antibodies

scientific article

Optimization of EGFR high positive cell isolation procedure by design of experiments methodology.

scientific article

Peptide mimotopes recognized by antibodies cetuximab and matuzumab induce a functionally equivalent anti-EGFR immune response

scientific article

Phage display of single-chain antibody constructs

scientific article

Preventive and therapeutic vaccination with PAP-3, a novel human prostate cancer peptide, inhibits carcinoma development in HLA transgenic mice.

scientific article

Production of stabilized scFv antibody fragments in the E. coli bacterial cytoplasm.

scientific article

Pseudomonas exotoxin A mutants. Replacement of surface-exposed residues in domain III with cysteine residues that can be modified with polyethylene glycol in a site-specific manner.

scientific article

Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38.

scientific article

Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes

scientific article

Recombinant single chain antibodies in bioelectrochemical sensors

scientific article published in December 2001

Removal of hepatitis C virus-infected cells by a zymogenized bacterial toxin

scientific article

Selection of antibodies from synthetic antibody libraries.

scientific article published on 08 January 2012

Selective targeting of melanoma and APCs using a recombinant antibody with TCR-like specificity directed toward a melanoma differentiation antigen.

scientific article

Suppression of hepatitis C virus by the flavonoid quercetin is mediated by inhibition of NS3 protease activity.

scientific article published on 16 August 2011

TAR1, a human anti-p53 single-chain antibody, restores tumor suppressor function to mutant p53 variants.

scientific article

Targeted filamentous bacteriophages as therapeutic agents

scientific article published on 01 March 2008

Targeting EGFR‐positive cancer cells with cetuximab–ZZ‐PE38: Results of in vitro and in vivo studies

scientific article published on September 10, 2012

The MUC1 oncoprotein as a functional target: immunotoxin binding to alpha/beta junction mediates cell killing

scientific article published on 01 January 2009

The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin

scientific article

The effect of hyaluronan injections into human knees on the number of bone and cartilage wear particles captured by bio-ferrography.

scientific article published on 6 September 2010

The isolation of novel phage display-derived human recombinant antibodies against CCR5, the major co-receptor of HIV

scientific article

Toxin-Based Therapeutic Approaches

scientific article published on October 28, 2010

Versatile protein microarray based on carbohydrate-binding modules

scientific article published in May 2005

chFRP5-ZZ-PE38, a large IgG-toxin immunoconjugate outperforms the corresponding smaller FRP5(Fv)-ETA immunotoxin in eradicating ErbB2-expressing tumor xenografts.

scientific article published on 14 August 2007