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List of works by Dirk Fasshauer

A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function

scientific article

A Structural Change Occurs upon Binding of Syntaxin to SNAP-25

scientific article published in Journal of Biological Chemistry

A coiled coil trigger site is essential for rapid binding of synaptobrevin to the SNARE acceptor complex

scientific article published on 20 April 2010

A conserved membrane attachment site in alpha-SNAP facilitates N-ethylmaleimide-sensitive factor (NSF)-driven SNARE complex disassembly.

scientific article published on 17 September 2009

A novel site of action for alpha-SNAP in the SNARE conformational cycle controlling membrane fusion

scientific article published on 19 December 2007

A transient N-terminal interaction of SNAP-25 and syntaxin nucleates SNARE assembly

scientific article

ADP ribosylation factor and a 14-kD polypeptide are associated with heparan sulfate-carrying post-trans-Golgi network secretory vesicles in rat hepatocytes.

scientific article

ARF and VAPP14: two proteins involved in the delivery of heparan sulfate proteoglycan from the trans-Golgi network to the plasma membrane

scientific article published on 01 September 1994

Alternative splicing of SNAP-25 regulates secretion through nonconservative substitutions in the SNARE domain.

scientific article

An elaborate classification of SNARE proteins sheds light on the conservation of the eukaryotic endomembrane system

scientific article

BET1 variants establish impaired vesicular transport as a cause for muscular dystrophy with epilepsy

scientific article published on 15 November 2021

Budding insights on cell polarity

article published in 2007

Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs

scientific article

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution

scientific article

Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide

scientific article

Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs

scientific article

Determinants of synaptobrevin regulation in membranes

scientific article published on 14 March 2007

Differences in the SNARE evolution of fungi and metazoa.

scientific article published on August 2009

Early endosomal SNAREs form a structurally conserved SNARE complex and fuse liposomes with multiple topologies

scientific article

Evidence for a conserved inhibitory binding mode between the membrane fusion assembly factors Munc18 and syntaxin in animals.

scientific article

Functional assays for the assessment of the pathogenicity of variants of GOSR2, an ER-to-Golgi SNARE involved in progressive myoclonus epilepsies.

scientific article published on 5 October 2017

Getting Nervous: An Evolutionary Overhaul for Communication

scientific article

High Cell Diversity and Complex Peptidergic Signaling Underlie Placozoan Behavior

scientific article published on 18 October 2018

Homo- and heterooligomeric SNARE complexes studied by site-directed spin labeling

scientific article

Identification of SNAP-47, a novel Qbc-SNARE with ubiquitous expression

scientific journal article

Identification of a minimal core of the synaptic SNARE complex sufficient for reversible assembly and disassembly

scientific journal article

Imaging the assembly and disassembly kinetics of cis-SNARE complexes on native plasma membranes

scientific journal article

Is assembly of the SNARE complex enough to fuel membrane fusion?

scientific article published on 3 March 2009

Kinetics of synaptotagmin responses to Ca2+ and assembly with the core SNARE complex onto membranes

scientific article published on 01 October 1999

Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical properties

scientific article (publication date: 28 May 1999)

Molecular machines governing exocytosis of synaptic vesicles

scientific article

Munc18-1 mutations that strongly impair SNARE-complex binding support normal synaptic transmission.

scientific article

Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide

scientific article

N- to C-Terminal SNARE Complex Assembly Promotes Rapid Membrane Fusion

scientific article published on 01 August 2006

Novel cell types, neurosecretory cells, and body plan of the early-diverging metazoan Trichoplax adhaerens.

scientific article

PI(4,5)P2-dependent regulation of exocytosis by amisyn, the vertebrate-specific competitor of synaptobrevin 2

scientific article published on 28 May 2020

Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment

scientific article

Phylogeny of the SNARE vesicle fusion machinery yields insights into the conservation of the secretory pathway in fungi

scientific article

Primordial neurosecretory apparatus identified in the choanoflagellate Monosiga brevicollis

scientific article

Rapid and selective binding to the synaptic SNARE complex suggests a modulatory role of complexins in neuroexocytosis

scientific article (publication date: 8 March 2002)

SNARE assembly and disassembly exhibit a pronounced hysteresis

scientific article published in February 2002

SNAREing the basis of multicellularity: consequences of protein family expansion during evolution

scientific article published on 10 July 2008

Selective interaction of complexin with the neuronal SNARE complex. Determination of the binding regions

scientific article (publication date: 30 June 2000)

Sequential N- to C-terminal SNARE complex assembly drives priming and fusion of secretory vesicles

scientific article published on 23 February 2006

Shedding light on the expansion and diversification of the Cdc48 protein family during the rise of the eukaryotic cell.

scientific article

Single vesicle millisecond fusion kinetics reveals number of SNARE complexes optimal for fast SNARE-mediated membrane fusion

scientific article

Single vesicle millisecond fusion kinetics reveals number of SNARE complexes optimal for fast SNARE-mediated membrane fusion

scientific article published in 2010

Single-molecule fluorescence resonance energy transfer reveals a dynamic equilibrium between closed and open conformations of syntaxin 1.

scientific article

Structural Changes Are Associated with SolubleN-Ethylmaleimide-sensitive Fusion Protein Attachment Protein Receptor Complex Formation

scientific article published in Journal of Biological Chemistry

Structural basis for the inhibitory role of tomosyn in exocytosis

scientific journal article

Structural insights into the SNARE mechanism

scientific article

Synaptobrevin N-terminally bound to syntaxin-SNAP-25 defines the primed vesicle state in regulated exocytosis

scientific article published on February 2010

Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids

scientific article

Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation

scientific article

The Ca2+ affinity of synaptotagmin 1 is markedly increased by a specific interaction of its C2B domain with phosphatidylinositol 4,5-bisphosphate

scientific article published on 24 July 2009

The Habc domain and the SNARE core complex are connected by a highly flexible linker

scientific journal article

The R-SNARE Motif of Tomosyn Forms SNARE Core Complexes with Syntaxin 1 and SNAP-25 and Down-regulates Exocytosis

scientific article published in Journal of Biological Chemistry

The SM protein Sly1 accelerates assembly of the ER-Golgi SNARE complex

scientific article

Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis

scientific article

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