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List of works by Pietro Pichierri

ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery

scientific article

Author Correction: Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation

scientific article published on 01 May 2019

BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks

scientific article

Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest

scientific article

CDK1 phosphorylates WRN at collapsed replication forks

scientific article published on 16 September 2016

Caffeine effect on the mitotic delay induced by G2 treatment with UVC or mitomycin C.

scientific article published on September 1998

Checkpoint-dependent and independent roles of the Werner syndrome protein in preserving genome integrity in response to mild replication stress

scientific article published on 28 October 2014

Chromosome radiosensitivity in human G2 lymphocytes and cell-cycle progression

scientific article published on 01 May 1999

Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51

scientific article published on 02 February 2021

DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein

Evidence that camptothecin-induced aberrations in the G2 phase of cell cycle of Chinese hamster ovary (CHO) cell lines is associated with transcription

article

Inducible SMARCAL1 knockdown in iPSC reveals a link between replication stress and altered expression of master differentiation genes

scientific article published on 17 October 2019

Investigation of G2-phase chromosomal radiosensitivity in hereditary non-polyposis colorectal cancer cells

scientific article published in July 2001

Perturbed replication induced genome wide or at common fragile sites is differently managed in the absence of WRN.

scientific article published on 11 June 2012

RAD51 AND MITOTIC FUNCTION OF MUS81 ARE ESSENTIAL FOR RECOVERY FROM LOW-DOSE OF CAMPTOTHECIN IN THE ABSENCE OF THE WRN EXONUCLEASE

Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation

scientific article published on 29 March 2019

Replication fork recovery and regulation of common fragile sites stability

scientific article published on 13 September 2014

Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway

scientific article published on 13 October 2008

SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells

scientific article published on 14 March 2017

Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells

scientific article published on 19 July 2016

Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function

scientific article

Targeting mismatch repair: a challenge for personalized chemotherapy

scholarly article by Pietro Pichierri & Margherita Bignami published June 2012 in Drug discovery today. Disease models

The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways

scientific article published on 26 February 2004

The Fanconi anemia pathway and the DNA interstrand cross-links repair

scientific article published on November 2003

The RAD9-RAD1-HUS1 (9.1.1) complex interacts with WRN and is crucial to regulate its response to replication fork stalling

scientific article

The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation

scientific article published on 12 March 2012

The WRN exonuclease domain protects nascent strands from pathological MRE11/EXO1-dependent degradation

scientific article published on 14 August 2015

The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase

scientific journal article

Transcription coupled repair efficiency determines the cell cycle progression and apoptosis after UV exposure in hamster cells.

scientific article published on March 2002

Understanding the molecular basis of common fragile sites instability: Role of the proteins involved in the recovery of stalled replication forks ⬇️

scientific article published on December 1, 2011

WRNIP1 protects stalled forks from degradation and promotes fork restart after replication stress.

scientific article published on 30 May 2016

Werner syndrome helicase activity is essential in maintaining fragile site stability

scientific article published on 21 January 2008

Werner syndrome helicase has a critical role in DNA damage responses in the absence of a functional fanconi anemia pathway

scientific article published on 18 July 2013

Werner syndrome protein, the MRE11 complex and ATR: menage-à-trois in guarding genome stability during DNA replication?

scientific article published in March 2004

Werner's syndrome lymphoblastoid cells are hypersensitive to topoisomerase II inhibitors in the G2 phase of the cell cycle

scientific article

Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle

scientific article published in March 2003

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