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List of works by Annapaola Franchitto

ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery

scientific article

BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks

scientific article

Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest

scientific article

Caffeine effect on the mitotic delay induced by G2 treatment with UVC or mitomycin C.

scientific article published on September 1998

Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation.

scientific article published on August 2010

Checkpoint-dependent and independent roles of the Werner syndrome protein in preserving genome integrity in response to mild replication stress

scientific article published on 28 October 2014

Chromosome radiosensitivity in human G2 lymphocytes and cell-cycle progression

scientific article published on 01 May 1999

Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51

scientific article published on 02 February 2021

Crosstalk between mismatch repair and base excision repair in human gastric cancer

scientific article published on 20 June 2016

Evidence that camptothecin-induced aberrations in the G2 phase of cell cycle of Chinese hamster ovary (CHO) cell lines is associated with transcription

article

Genome instability at common fragile sites: searching for the cause of their instability

scientific article published on 05 September 2013

Investigation of G2-phase chromosomal radiosensitivity in hereditary non-polyposis colorectal cancer cells

scientific article published in July 2001

Perturbed replication induced genome wide or at common fragile sites is differently managed in the absence of WRN.

scientific article published on 11 June 2012

Protecting genomic integrity during DNA replication: correlation between Werner's and Bloom's syndrome gene products and the MRE11 complex.

scientific article

RecQ helicases and topoisomerases: implications for genome stability in humans.

scientific article published on June 2007

Replication fork recovery and regulation of common fragile sites stability

scientific article published on 13 September 2014

Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway

scientific article published on 13 October 2008

Replication-dependent DNA damage response triggered by roscovitine induces an uncoupling of DNA replication proteins.

scientific article

Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function

scientific article

Terminally differentiated muscle cells are defective in base excision DNA repair and hypersensitive to oxygen injury.

scholarly article

The G2-phase decatenation checkpoint is defective in Werner syndrome cells

scientific article

The RAD9-RAD1-HUS1 (9.1.1) complex interacts with WRN and is crucial to regulate its response to replication fork stalling

scientific article

The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation

scientific article published on 12 March 2012

The WRN exonuclease domain protects nascent strands from pathological MRE11/EXO1-dependent degradation

scientific article published on 14 August 2015

The Werner syndrome protein: linking the replication checkpoint response to genome stability ⬇️

scientific article published on March 1, 2011

The logic and regulation of cell cycle exit and reentry.

scientific article published on January 2008

The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase

scientific journal article

Understanding the molecular basis of common fragile sites instability: Role of the proteins involved in the recovery of stalled replication forks ⬇️

scientific article published on December 1, 2011

WRNIP1 protects stalled forks from degradation and promotes fork restart after replication stress.

scientific article published on 30 May 2016

Werner syndrome helicase activity is essential in maintaining fragile site stability

scientific article published on 21 January 2008

Werner syndrome protein, the MRE11 complex and ATR: menage-à-trois in guarding genome stability during DNA replication?

scientific article published in March 2004

Werner's syndrome lymphoblastoid cells are hypersensitive to topoisomerase II inhibitors in the G2 phase of the cell cycle

scientific article

Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle

scientific article published in March 2003

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