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List of works by James Bruce Stewart

A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency.

scientific article published on 16 April 2018

Accurate mapping of mitochondrial DNA deletions and duplications using deep sequencing

scientific article published on 14 December 2020

Addressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age.

scientific article

Author Correction: MitoTALEN reduces mutant mtDNA load and restores tRNA levels in a mouse model of heteroplasmic mtDNA mutation

scientific article published on 01 December 2018

Characterization of mature mitochondrial transcripts in Drosophila, and the implications for the tRNA punctuation model in arthropods

scientific article published on 18 June 2009

Characterization of the sea urchin mitochondrial transcription factor A reveals unusual features.

scientific article published in November 2013

Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies

scientific article published on 10 November 2015

Current Progress with Mammalian Models of Mitochondrial DNA Disease

scientific article published on 25 October 2020

Delivery of mtZFNs into Early Mouse Embryos

scientific article published on 01 January 2018

Extreme heterogeneity of human mitochondrial DNA from organelles to populations

scientific article published on 28 September 2020

Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo

scientific article published on 24 September 2018

Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.

scientific article published on 3 August 2016

In vivo mutagenesis reveals that OriL is essential for mitochondrial DNA replication

scientific article published on 23 October 2012

Incorporating Molecular Evolution into Phylogenetic Analysis, and a New Compilation of Conserved Polymerase Chain Reaction Primers for Animal Mitochondrial DNA

article

Increased Total mtDNA Copy Number Cures Male Infertility Despite Unaltered mtDNA Mutation Load

scientific article

Insect mitochondrial genomics 2: The complete mitochondrial genome sequence of a giant stonefly, Pteronarcys princeps, asymmetric directional mutation bias, and conserved plecopteran A+T-region elements

scientific article

Insect mitochondrial genomics 3: the complete mitochondrial genome sequences of representatives from two neuropteroid orders: a dobsonfly (order Megaloptera) and a giant lacewing and an owlfly (order Neuroptera).

scientific article

Insect mitochondrial genomics: the complete mitochondrial genome sequence of the meadow spittlebug Philaenus spumarius (Hemiptera: Auchenorrhyncha: Cercopoidae).

scientific article

Keeping mtDNA in shape between generations

scientific article

LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

scientific article

MTERF1 binds mtDNA to prevent transcriptional interference at the light-strand promoter but is dispensable for rRNA gene transcription regulation

scientific journal article

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria.

scientific article published on 23 March 2018

MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation

scientific article published on 24 September 2018

Mitochondrial DNA deletions are associated with non-B DNA conformations

scientific article

Mitochondrial DNA heteroplasmy is modulated during oocyte development propagating mutation transmission

scientific article published on 08 December 2021

Mitochondrial DNA: Radically free of free-radical driven mutations

scientific article

Mitochondrial stress response triggered by defects in protein synthesis quality control

scientific article published on 25 January 2019

Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse

scientific article published on 03 April 2019

No recombination of mtDNA after heteroplasmy for 50 generations in the mouse maternal germline.

scientific article published on 25 October 2013

Overactive mitochondrial DNA replisome causes neonatal heart failure via ferroptosis

scientific article published on 4 April 2022

Phylogenetic and genomic analysis of the complete mitochondrial DNA sequence of the spotted asparagus beetle Crioceris duodecimpunctata

scientific article published on March 2003

Progressive loss of mitochondrial DNA in thymidine kinase 2-deficient mice

scientific journal article

Purifying selection of mtDNA and its implications for understanding evolution and mitochondrial disease

scientific article published on 01 September 2008

Similar patterns of clonally expanded somatic mtDNA mutations in the colon of heterozygous mtDNA mutator mice and ageing humans

scientific article

Simultaneous DNA and RNA Mapping of Somatic Mitochondrial Mutations across Diverse Human Cancers

scientific article published on 30 June 2015

The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster

scientific article

The challenges of mitochondrial replacement.

scientific article

The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease

scientific article published in August 2015

The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication.

scientific article published on 22 June 2015

Tissue-specific modulation of mitochondrial DNA segregation by a defect in mitochondrial division.

scientific article published on 17 December 2015

Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins

scientific article

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission

scientific article