List of works - Colin M Tice

Biochemical mode of action and differential activity of new ecdysone agonists against mosquitoes and moths.

scientific article published on April 2005

Biphenyl/diphenyl ether renin inhibitors: filling the S1 pocket of renin via the S3 pocket

scientific article

Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core

scientific article

Design and optimization of renin inhibitors: Orally bioavailable alkyl amines

scientific article

Discovery and optimization of adamantyl carbamate inhibitors of 11β-HSD1.

scientific article published on 7 September 2010

Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility

scientific article

Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist

scientific article

Evaluation of solution and solid-phase approaches to the synthesis of libraries of alpha,alpha-disubstituted-alpha-acylaminoketones

scientific article published in November 2005

Highly flexible ligand binding pocket of ecdysone receptor: a single amino acid change leads to discrimination between two groups of nonsteroidal ecdysone agonists.

scientific article

Non-canonical modulators of nuclear receptors.

scientific article

Optimization of alpha-acylaminoketone ecdysone agonists for control of gene expression

scientific article

Selecting the right compounds for screening: does Lipinski's Rule of 5 for pharmaceuticals apply to agrochemicals?

scientific article published in January 2001

Selecting the right compounds for screening: use of surface-area parameters

scientific article published in March 2002

Spirocyclic ureas: orally bioavailable 11 beta-HSD1 inhibitors identified by computer-aided drug design

scientific article published on 4 January 2010

Structure based design of 11β-HSD1 inhibitors.

scientific article

Structure-activity relationships of phenylcyclohexene and biphenyl antitubulin compounds against plant and mammalian cells

scientific article

Structure-based design and synthesis of 1,3-oxazinan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase type 1.

scientific article published on 4 August 2011

Synthesis of biotin conjugates of the antifungal compound cymoxanil

scientific article published in April 2002

The medicinal chemistry of liver X receptor (LXR) modulators

scientific article published on 28 May 2014

The use of spirocyclic scaffolds in drug discovery.

scientific article

The utilization of spirocyclic scaffolds in novel drug discovery.

scientific article

Tight-Binding Hydroxypyrazole HIV-1 Nef Inhibitors Suppress Viral Replication in Donor Mononuclear Cells and Reverse Nef-Mediated MHC-I Downregulation

scientific article published on 16 December 2019

List of works by Colin M Tice

Biochemical mode of action and differential activity of new ecdysone agonists against mosquitoes and moths.

Biphenyl/diphenyl ether renin inhibitors: filling the S1 pocket of renin via the S3 pocket

Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core

Design and optimization of renin inhibitors: Orally bioavailable alkyl amines

Discovery and optimization of adamantyl carbamate inhibitors of 11β-HSD1.

Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility

Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist

Evaluation of solution and solid-phase approaches to the synthesis of libraries of alpha,alpha-disubstituted-alpha-acylaminoketones

Highly flexible ligand binding pocket of ecdysone receptor: a single amino acid change leads to discrimination between two groups of nonsteroidal ecdysone agonists.

Non-canonical modulators of nuclear receptors.

Optimization of alpha-acylaminoketone ecdysone agonists for control of gene expression

Selecting the right compounds for screening: does Lipinski's Rule of 5 for pharmaceuticals apply to agrochemicals?

Selecting the right compounds for screening: use of surface-area parameters

Spirocyclic ureas: orally bioavailable 11 beta-HSD1 inhibitors identified by computer-aided drug design

Structure based design of 11β-HSD1 inhibitors.

Structure-activity relationships of phenylcyclohexene and biphenyl antitubulin compounds against plant and mammalian cells

Structure-based design and synthesis of 1,3-oxazinan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase type 1.

Synthesis of biotin conjugates of the antifungal compound cymoxanil

The medicinal chemistry of liver X receptor (LXR) modulators

The use of spirocyclic scaffolds in drug discovery.

The utilization of spirocyclic scaffolds in novel drug discovery.

Tight-Binding Hydroxypyrazole HIV-1 Nef Inhibitors Suppress Viral Replication in Donor Mononuclear Cells and Reverse Nef-Mediated MHC-I Downregulation