List of works - Jillian Madine

1H, 15N and 13C assignment of the amyloidogenic protein medin using fast-pulsing NMR techniques.

scientific article published on 16 September 2015

An NMR strategy for obtaining multiple conformational constraints for 15N-13C spin-pair labelled organic solids.

scientific article published on 10 October 2006

Cofactor-mediated amyloidogenesis

scientific article published on 06 March 2019

Comparison of aggregation enhancement and inhibition as strategies for reducing the cytotoxicity of the aortic amyloid polypeptide medin.

scientific article

Cross-beta spine architecture of fibrils formed by the amyloidogenic segment NFGSVQFV of medin from solid-state NMR and X-ray fiber diffraction measurements.

scientific article published in April 2009

Design of an N-methylated peptide inhibitor of alpha-synuclein aggregation guided by solid-state NMR.

scientific article published on 30 May 2008

Development of amyloid beta gold nanorod aggregates as optoacoustic probes ⬇️

scientific article published on 25 March 2022

Evaluation of beta-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation.

scientific article published in August 2009

Exploiting a (13)C-labelled heparin analogue for in situ solid-state NMR investigations of peptide-glycan interactions within amyloid fibrils

scientific article

Exploring the potential of rapid evaporative ionization mass spectrometry (Intelligent Knife) for point-of-care testing in aortic surgery

publication published on 01 September 2021

Heparin promotes the rapid fibrillization of a peptide with low intrinsic amyloidogenicity.

scientific article published on 6 December 2013

Idiopathic degenerative thoracic aneurysms are associated with increased aortic medial amyloid

scientific article published on 18 June 2019

Insights into the Origin of Distinct Medin Fibril Morphologies Induced by Incubation Conditions and Seeding.

scientific article published on 3 May 2018

Insights into the molecular architecture of a peptide nanotube using FTIR and solid-state NMR spectroscopic measurements on an aligned sample

scientific article published on 16 August 2013

Isolation and purification of recombinant immunoglobulin light chain variable domains from the periplasmic space of Escherichia coli

scientific article published in PLoS ONE

Measurement of multiple torsional angles from one-dimensional solid-state NMR spectra: application to the conformational analysis of a ligand in its biological receptor site.

scientific article published on 28 September 2010

Medin aggregation causes cerebrovascular dysfunction in aging wild-type mice

scientific article published on 08 September 2020

Membrane interactions of peptides representing the polybasic regions of three Rho GTPases are sensitive to the distribution of arginine and lysine residues.

scientific article

Nanoliposomes protect against human arteriole endothelial dysfunction induced by β-amyloid peptide

scientific article published on 8 October 2015

Screening molecular associations with lipid membranes using natural abundance 13C cross-polarization magic-angle spinning NMR and principal component analysis

scientific article published on 01 August 2004

Site-specific identification of an aβ fibril-heparin interaction site by using solid-state NMR spectroscopy

scientific article

Solid-state NMR reveals differences in the packing arrangements of peptide aggregates derived from the aortic amyloid polypeptide medin

scientific article published on 21 November 2011

Structural insights into the polymorphism of amyloid-like fibrils formed by region 20-29 of amylin revealed by solid-state NMR and X-ray fiber diffraction

scientific article

Studies of the aggregation of an amyloidogenic α-synuclein peptide fragment

scientific article published on 01 November 2005

The effects of alpha-synuclein on phospholipid vesicle integrity: a study using 31P NMR and electron microscopy.

scientific article published in September 2008

Using an NMR metabolomics approach to investigate the pathogenicity of amyloid-beta and alpha-synuclein

scientific article published on 29 October 2017

List of works by Jillian Madine

1H, 15N and 13C assignment of the amyloidogenic protein medin using fast-pulsing NMR techniques.

An NMR strategy for obtaining multiple conformational constraints for 15N-13C spin-pair labelled organic solids.

Cofactor-mediated amyloidogenesis

Comparison of aggregation enhancement and inhibition as strategies for reducing the cytotoxicity of the aortic amyloid polypeptide medin.

Cross-beta spine architecture of fibrils formed by the amyloidogenic segment NFGSVQFV of medin from solid-state NMR and X-ray fiber diffraction measurements.

Design of an N-methylated peptide inhibitor of alpha-synuclein aggregation guided by solid-state NMR.

Development of amyloid beta gold nanorod aggregates as optoacoustic probes ⬇️

Evaluation of beta-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation.

Exploiting a (13)C-labelled heparin analogue for in situ solid-state NMR investigations of peptide-glycan interactions within amyloid fibrils

Exploring the potential of rapid evaporative ionization mass spectrometry (Intelligent Knife) for point-of-care testing in aortic surgery

Heparin promotes the rapid fibrillization of a peptide with low intrinsic amyloidogenicity.

Idiopathic degenerative thoracic aneurysms are associated with increased aortic medial amyloid

Insights into the Origin of Distinct Medin Fibril Morphologies Induced by Incubation Conditions and Seeding.

Insights into the molecular architecture of a peptide nanotube using FTIR and solid-state NMR spectroscopic measurements on an aligned sample

Isolation and purification of recombinant immunoglobulin light chain variable domains from the periplasmic space of Escherichia coli

Measurement of multiple torsional angles from one-dimensional solid-state NMR spectra: application to the conformational analysis of a ligand in its biological receptor site.

Medin aggregation causes cerebrovascular dysfunction in aging wild-type mice

Membrane interactions of peptides representing the polybasic regions of three Rho GTPases are sensitive to the distribution of arginine and lysine residues.

Nanoliposomes protect against human arteriole endothelial dysfunction induced by β-amyloid peptide

Screening molecular associations with lipid membranes using natural abundance 13C cross-polarization magic-angle spinning NMR and principal component analysis

Site-specific identification of an aβ fibril-heparin interaction site by using solid-state NMR spectroscopy

Solid-state NMR reveals differences in the packing arrangements of peptide aggregates derived from the aortic amyloid polypeptide medin

Structural insights into the polymorphism of amyloid-like fibrils formed by region 20-29 of amylin revealed by solid-state NMR and X-ray fiber diffraction

Studies of the aggregation of an amyloidogenic α-synuclein peptide fragment

The effects of alpha-synuclein on phospholipid vesicle integrity: a study using 31P NMR and electron microscopy.

Using an NMR metabolomics approach to investigate the pathogenicity of amyloid-beta and alpha-synuclein