Search filters

List of works by Paul Dark

'In a dark place, we find ourselves': light intensity in critical care units.

scientific article published on 7 February 2017

16S pan-bacterial PCR can accurately identify patients with ventilator-associated pneumonia

scientific article published on 14 December 2016

A 27-Year-Old Woman With Acute, Severe Asthma Who Developed Respiratory Failure

scientific article published on 01 March 2010

Accuracy of LightCycler(R) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review protocol

scientific article

Accuracy of LightCycler(®) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis.

scientific article

Acute intestinal failure.

scientific article published on August 2010

Acute management of severe traumatic brain injury

scientific article published in January 2004

Airway clearance techniques and use of mucoactive agents for adult critically ill patients with acute respiratory failure: a qualitative study exploring UK physiotherapy practice

scientific article published on 01 July 2020

An objective analysis of an accident flying squad

scientific article published on 01 June 1990

Biomarker-guided antibiotic cessation in sepsis: evidence and future challenges.

scientific article published in March 2018

Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation

scientific article published on 03 December 2019

BreathDx - molecular analysis of exhaled breath as a diagnostic test for ventilator-associated pneumonia: protocol for a European multicentre observational study

scientific article

Can a score derived from the Critical Care Minimum Data Set be used as a marker of organ dysfunction? - a pilot study

scientific article

Characterising the research profile of the critical care physiotherapy workforce and engagement with critical care research: a UK national survey.

scientific article

Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection

scientific article published on 13 July 2009

Combined molecular gram typing and high-resolution melting analysis for rapid identification of a syndromic panel of bacteria responsible for sepsis-associated bloodstream infection

scientific article

Comparing the systolic blood pressure (SBP) and pulse rate (PR) in injured children with and without traumatic brain injury

scientific article

Cyclic neutropenia--unusual cause of acute abdomen. Report of a case

scientific article

Detecting sepsis-associated bloodstream infection acquired in intensive care using multi-pathogen real-time PCR.

scientific article published on 18 August 2009

Detection and quantification of exhaled volatile organic compounds in mechanically ventilated patients - comparison of two sampling methods

scientific article published on 26 October 2020

Diagnostic accuracy of SeptiFast multi-pathogen real-time PCR in the setting of suspected healthcare-associated bloodstream infection

scientific article published on 19 November 2014

Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia.

scientific article

Differences between brain and rectal temperatures during routine critical care of patients with severe traumatic brain injury

scientific article published in August 2005

Duration of breast feeding and adult arterial distensibility. Statistical analysis was unclear

scientific article published on 01 September 2001

Editorial IV: physical and pharmacological restraint of critically ill patients: clinical facts and ethical considerations

scientific article published on 01 June 2004

Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial

scientific article published on 16 July 2016

Effects of sustained post-traumatic shock and initial fluid resuscitation on extravascular lung water content and pulmonary vascular pressures in a porcine model of shock

scientific article published in August 2003

Erratum to: 'Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial'.

scientific article published on 26 September 2016

Estimation of errors in determining intrathoracic blood volume using the single transpulmonary thermal dilution technique in hypovolemic shock

scientific article published in October 2005

Estimation of errors in determining intrathoracic blood volume using thermal dilution in pigs with acute lung injury and haemorrhage

scientific article published on 26 July 2004

Fluid replacement via the rectum for treatment of hypovolaemic shock in an animal model.

scientific article

Gadolinium-enhanced magnetic resonance imaging for renovascular disease and nephrogenic systemic fibrosis: critical review of the literature and UK experience

scientific article published on April 2009

Guidelines on the management of acute respiratory distress syndrome.

scientific article published on 24 May 2019

Hemodynamic responses to fluid resuscitation after blunt trauma

scientific article published in February 2002

Hypothermia in trauma patients

scientific article published on 01 March 1996

I spy with my little eye something beginning with S: spotting sepsis

scientific article published in September 2016

Instantaneous versus average wave speed calculation in large mammals under acute hemorrhage

scientific article published in January 2007

Investigation of systemic and mesenteric inflammatory signaling and gut-derived endothelial toxicity in patients undergoing high-risk abdominal aortic surgery.

scientific article published in August 2011

Kaleidomaps: A New Technique for the Visualization of Multivariate Time-Series Data

Monitoring the circulatory responses of shocked patients during fluid resuscitation in the emergency department

scientific article published on 01 February 2000

More research is required to understand factors influencing antibiotic prescribing in complex conditions like suspected ventilator-associated pneumonia

scientific article published on 01 July 2020

Nanotools for Sepsis Diagnosis and Treatment

scientific article published on 25 November 2020

Non-invasive cardiac output assessment in children

scientific article published in March 1999

On the retirement of Professor Rod Little.

scientific article published in January 2003

Organ-specific effects of oxygen and carbogen gas inhalation on tissue longitudinal relaxation times

scientific article published in September 2007

Patient agitation and its management in adult critical care: a systematic review and narrative synthesis.

scientific article published on 4 January 2018

Protein corona fingerprinting to differentiate sepsis from non-infectious systemic inflammation

scientific article published on 01 May 2020

RECOVERY- Respiratory Support: Respiratory Strategies for patients with suspected or proven COVID-19 respiratory failure; Continuous Positive Airway Pressure, High-flow Nasal Oxygen, and standard care: A structured summary of a study protocol for a

scientific article published on 29 July 2020

Rapid detection of health-care-associated bloodstream infection in critical care using multipathogen real-time polymerase chain reaction technology: a diagnostic accuracy study and systematic review

scientific article published on May 2015

Removal of Contaminant DNA by Combined UV-EMA Treatment Allows Low Copy Number Detection of Clinically Relevant Bacteria Using Pan-Bacterial Real-Time PCR

scientific article published on 14 July 2015

Retrospective analysis of cancer patients admitted to a tertiary centre with suspected neutropenic sepsis: Are C-reactive protein and neutrophil count useful prognostic biomarkers?

scientific article published on 04 December 2017

Sepsis: the LightCycler SeptiFast Test MGRADE®, SepsiTest™ and IRIDICA BAC BSI assay for rapidly identifying bloodstream bacteria and fungi - a systematic review and economic evaluation.

scientific article published in June 2016

Sevoflurane

scientific article published on 01 May 1998

Surveillance for lower airway pathogens in mechanically ventilated patients by metabolomic analysis of exhaled breath: a case-control study.

scientific article published on 6 February 2015

Surveillance non-directed bronchial lavage allows confident use of focused antibiotics in the management of ventilator-associated pneumonia

scientific article published on 09 March 2010

Synthesis of qualitative research studies regarding the factors surrounding UK critical care trial infrastructure

scientific article published on 22 December 2019

Systemic arterial pressure wave reflections during acute hemorrhage.

scientific article published on May 2006

Systolic hypertension and the response to blunt trauma in infants and children.

scientific article published on September 2002

Testing the validity of the ATLS classification of hypovolaemic shock

scientific article published on 01 September 2010

The challenge of recognising sepsis: Future nanotechnology solutions

scientific article published on 18 December 2019

The clinical diagnostic accuracy of rapid detection of healthcare-associated bloodstream infection in intensive care using multipathogen real-time PCR technology.

scientific article

The diagnostic future for bloodstream infections?

scientific article published on 28 October 2010

The effectiveness of frequent antibiotic use in reducing the risk of infection-related hospital admissions: results from two large population-based cohorts

scientific article published on 02 March 2020

The management of agitation in adult critical care: Views and opinions from the multi-disciplinary team using a survey approach

scientific article published on 14 June 2019

The potential role of exhaled breath analysis in the diagnostic process of pneumonia - a systematic review.

scientific article

The validity of trans-esophageal Doppler ultrasonography as a measure of cardiac output in critically ill adults

scientific article published on 11 September 2004

Understanding and Enhancing Sepsis Survivorship. Priorities for Research and Practice

scientific article published on 01 October 2019

Using statistics and mathematical modelling to understand infectious disease outbreaks: COVID-19 as an example

scientific article published on 04 July 2020

Vital signs and estimated blood loss in patients with major trauma: testing the validity of the ATLS classification of hypovolaemic shock

scientific article published on 23 February 2011