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List of works by Patrick Cahan

A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development.

scientific article published in April 2018

A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen

scientific article published on 01 May 2019

A conversation with ChatGPT on the role of computational systems biology in stem cell research ⬇️

scientific article published in January 2023

A high-resolution map of segmental DNA copy number variation in the mouse genome

scientific article (publication date: 5 January 2007)

A nontranscriptional role for Oct4 in the regulation of mitotic entry

scientific article

A single cell transcriptional atlas of early synovial joint development

scientific article published on 24 June 2020

A single cell transcriptional portrait of embryoid body differentiation and comparison to progenitors of the developing embryo.

scientific article published on 29 July 2018

A systems biology pipeline identifies regulatory networks for stem cell engineering

scientific article published on 01 July 2019

Assessment of engineered cells using CellNet and RNA-seq.

scientific article published on 27 April 2017

Author Correction: A systems biology pipeline identifies regulatory networks for stem cell engineering

scientific article published on 01 August 2019

Cell Fate Engineering Tools for iPSC Disease Modeling

scientific article published on 01 January 2019

CellNet: network biology applied to stem cell engineering

scientific article

Chromatin-modifying enzymes as modulators of reprogramming

scientific article

Computational Tools for Stem Cell Biology.

scientific article published on 15 June 2016

Deconstructing transcriptional heterogeneity in pluripotent stem cells

scientific article published on December 2014

Defining cellular identity through network biology

scientific article published on January 2014

Dissecting engineered cell types and enhancing cell fate conversion via CellNet

scientific article published on August 2014

Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells

scientific article

Enabling direct fate conversion with network biology

scientific article published in February 2016

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

scientific article published on December 2016

Epigenetic memory in induced pluripotent stem cells

scientific article (publication date: 16 September 2010)

Erratum: Deconstructing transcriptional heterogeneity in pluripotent stem cells

scientific article published in Nature

Evaluating the transcriptional fidelity of cancer models

scientific article published on 29 April 2021

Genomic profiling of acquired resistance to apoptosis in cells derived from human atherosclerotic lesions: potential role of STATs, cyclinD1, BAD, and Bcl-XL.

scientific article

Hippo pathway activity influences liver cell fate

scientific article

Identification and distribution of sequences having similarity to mitochondrial plasmids in mitochondrial genomes of filamentous fungi

scientific article published on 13 May 2005

Integrated genomics of susceptibility to alkylator-induced leukemia in mice

scientific article

Interleukin-36γ-producing macrophages drive IL-17-mediated fibrosis

scientific article published on 01 October 2019

Investigating monogenic and complex diseases with pluripotent stem cells

scientific article published on 09 March 2011

Involvement of HTLV-I Tax and CREB in aneuploidy: a bioinformatics approach

scientific article published on 05 July 2006

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency

scientific article

Multi-scale cellular engineering: From molecules to organ-on-a-chip

scientific article published on 03 March 2020

Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma

scientific article

Origins and implications of pluripotent stem cell variability and heterogeneity

scientific article published on 15 May 2013

Poly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA component

scientific journal article

Polycomb Repressive Complex 2 Regulates Normal Development of the Mouse Heart ⬇️

scientific article published on December 8, 2011

Posttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease.

scientific article published on 02 August 2016

Programming Morphogenesis through Systems and Synthetic Biology.

scientific article published on 8 December 2017

Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression

scientific article

SingleCellNet: A Computational Tool to Classify Single Cell RNA-Seq Data Across Platforms and Across Species

scientific article published on 31 July 2019

Structural variation of the mouse natural killer gene complex.

scientific article

Systems pharmacogenomics in yeast

scientific article

TGF-β inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors.

scientific article published on 24 October 2016

The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells

scientific article published on 08 March 2009

The transcriptional landscape of hematopoietic stem cell ontogeny

scientific article published on November 2012

Transcriptional Landscape of Cardiomyocyte Maturation

scientific article

Understanding development and stem cells using single cell-based analyses of gene expression.

scientific article published on January 2017

wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data

scientific article

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