Search filters

List of works by Roman Fischer

A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism ⬇️

scientific article

A TFEB nuclear export signal integrates amino acid supply and glucose availability.

scientific article published on 11 July 2018

A modified density gradient proteomic-based method to analyze endolysosomal proteins in cardiac tissue

scientific article published on 04 August 2021

A novel workflow combining plaque imaging, plaque and plasma proteomics identifies biomarkers of human coronary atherosclerotic plaque disruption

scientific article

A photoreactive small-molecule probe for 2-oxoglutarate oxygenases

scientific article

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

scientific article published in Nature Communications

Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses

scientific article published on 23 May 2016

Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes

scientific article

Ancient proteins from ceramic vessels at Çatalhöyük West reveal the hidden cuisine of early farmers

scientific article published in Nature Communications

Ancient proteins resolve the evolutionary history of Darwin’s South American ungulates

scientific article (publication date: 18 March 2015)

Animal origin of 13th-century uterine vellum revealed using noninvasive peptide fingerprinting

scientific article

Bi-directional signaling by membrane-bound KitL induces proliferation and coordinates thymic endothelial cell and thymocyte expansion

scientific article published in Nature Communications

Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability

scientific article

Colonic epithelial cell diversity in health and inflammatory bowel disease

scientific article published on 27 February 2019

Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix

scientific article published in Nature Communications

Comparative evaluation of label-free SINQ normalized spectral index quantitation in the central proteomics facilities pipeline

scientific article published on 8 June 2011

Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells

scientific article published on 30 August 2019

Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27.

scientific article published on February 2014

Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis

scientific article published on 24 July 2015

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming

scientific article

Defining the HLA class I-associated viral antigen repertoire from HIV-1-infected human cells

scientific article published on 15 October 2015

Detection of BK virus in urine from renal transplant subjects by mass spectrometry.

scientific article

Detection of multiple autoantibodies in patients with ankylosing spondylitis using nucleic acid programmable protein arrays

scientific article published on February 2012

Development of a Sensitive, Scalable Method for Spatial, Cell-Type-Resolved Proteomics of the Human Brain

article

Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells

scientific article published on 06 June 2019

Discovery of candidate serum proteomic and metabolomic biomarkers in ankylosing spondylitis

scientific article

Expanding Proteome Coverage with CHarge Ordered Parallel Ion aNalysis (CHOPIN) Combined with Broad Specificity Proteolysis.

scientific article published on 6 February 2017

Expanding the yeast protein arginine methylome

scientific article published on 5 June 2015

Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers: implications for autoimmunity in rheumatoid arthritis

scientific article

Extracellular vesicle integrins act as a nexus for platelet adhesion in cerebral microvessels

scientific article published on 01 November 2019

FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration

scientific article published on 18 January 2018

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency

scientific article published on 03 December 2021

GOAT--a simple LC-MS/MS gradient optimization tool

scientific article published on 15 May 2014

Gel-aided sample preparation (GASP)--a simplified method for gel-assisted proteomic sample generation from protein extracts and intact cells

scientific article published on 5 February 2015

Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways

scientific article

Identification of an immunodominant peptide from citrullinated tenascin-C as a major target for autoantibodies in rheumatoid arthritis

scientific article published on 9 December 2015

Identification of distinct circulating exosomes in Parkinson's disease

scientific article

Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300

scientific article published on 05 August 2020

Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency

scientific article published on 14 March 2013

Integrative Phosphoproteomics Links IL-23R Signaling with Metabolic Adaptation in Lymphocytes

scientific article published on 15 April 2016

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

scientific article published on 02 July 2020

LARP1 isoform expression in human cancer cell lines

scientific article published on 14 April 2020

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates

scientific article published on 10 September 2019

Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair

scientific article published on 27 October 2016

Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells

scientific article published on September 2017

New criteria for the molecular identification of cereal grains associated with archaeological artefacts

scientific article

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

scientific article

Optimal translational termination requires C4 lysyl hydroxylation of eRF1.

scientific article published on 30 January 2014

PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions

scientific article published on 31 December 2016

Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne

scientific article

Palaeoproteomics resolves sloth relationships

scientific article published on 06 June 2019

PfHPRT: a new biomarker candidate of acute Plasmodium falciparum infection

scientific article published on 12 February 2013

Phenotypic manifestation of α-synuclein strains derived from Parkinson's disease and multiple system atrophy in human dopaminergic neurons

scientific article published on 21 June 2021

Phosphoproteomics of CD2 signaling reveals AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells

scientific article published on 12 May 2020

Phylogeny by a polyphasic approach of the order Caulobacterales, proposal of Caulobacter mirabilis sp. nov., Phenylobacterium haematophilum sp. nov. and Phenylobacterium conjunctum sp. nov., and emendation of the genus Phenylobacterium

scientific article

Plasma degradome affected by variable storage of human blood

scientific article published on 26 September 2016

Protein sequences bound to mineral surfaces persist into deep time ⬇️

scientific article

Proteo-metabolomics reveals compensation between ischemic and non-injured contralateral kidneys after reperfusion.

scientific article

Proteomic changes in response to crystal formation in Drosophila Malpighian tubules

scientific article published on 11 April 2016

Proteomic evidence of dietary sources in ancient dental calculus

scientific article published on 18 July 2018

Proteomic profiling of the brain of mice with experimental cerebral malaria

scientific article published on 5 June 2017

Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases

scientific article published on 01 October 2018

Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation.

scientific article

RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events

scientific article

RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes.

scientific article published on 05 October 2016

Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling

scientific article

SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.

scientific article published on 27 May 2016

SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication

scientific article published on 17 July 2019

Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche

scientific journal article

Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells

scientific article

Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib

scientific article

Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells

scientific article

TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts

scientific article published on 09 March 2020

Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation

scientific article published in Scientific Reports

The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks

scientific article published on 26 January 2021

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases

article

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function

scientific article published on 03 June 2021

The identification of archaeological eggshell using peptide markers

scholarly article by Samantha Presslee published in January 2017

Two birds with one stone: doing metabolomics with your proteomics kit.

scientific article

Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity

scientific article published in 2024

Paulina is supported by:

About Paulina

Help