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List of works by Andrés F. Muro

A major fraction of fibronectin present in the extracellular matrix of tissues is plasma-derived.

scientific article

A polar mechanism coordinates different regions of alternative splicing within a single gene.

scientific article

A translationally optimized AAV-UGT1A1 vector drives safe and long-lasting correction of Crigler-Najjar syndrome

scientific article published on 20 July 2016

Absence of regulated splicing of fibronectin EDA exon reduces atherosclerosis in mice.

scientific article published on 27 September 2007

Age-dependent pattern of cerebellar susceptibility to bilirubin neurotoxicity in vivo in mice

scientific article published on 25 July 2014

Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hyperbilirubinemia.

scientific article

Alternative splicing of fibronectin: a mouse model demonstrates the identity of in vitro and in vivo systems and the processing autonomy of regulated exons in adult mice.

scientific article published on January 2004

An essential role for fibronectin extra type III domain A in pulmonary fibrosis.

scientific article published on 20 December 2007

Attenuation of neuro-inflammation improves survival and neurodegeneration in a mouse model of severe neonatal hyperbilirubinemia.

scientific article published on 16 February 2018

Beclin-1-mediated activation of autophagy improves proximal and distal urea cycle disorders

scientific article published on 28 December 2020

Bilirubin-Induced Oxidative Stress Leads to DNA Damage in the Cerebellum of Hyperbilirubinemic Neonatal Mice and Activates DNA Double-Strand Break Repair Pathways in Human Cells

Brief Report: Alternative Splicing of Extra Domain A (EIIIA) of Fibronectin Plays a Tissue-Specific Role in Hematopoietic Homeostasis.

scientific article

CPEB2, CPEB3 and CPEB4 are coordinately regulated by miRNAs recognizing conserved binding sites in paralog positions of their 3'-UTRs

scientific article published on 25 July 2010

Characterisation and chromosomal localisation of the rat alpha- and beta-adducin-encoding genes

scientific journal article

Characterization of the distal polyadenylation site of the ß-adducin (Add2) pre-mRNA.

scientific article

Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway

scientific article

Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases

scientific article published on 18 June 2019

DNA sequencing by the chemical method: a 10 minute procedure for the G+A reaction

scientific article published on 01 October 1993

EDA fibronectin-TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis

scientific article published on 07 February 2019

EDA-containing cellular fibronectin induces fibroblast differentiation through binding to alpha4beta7 integrin receptor and MAPK/Erk 1/2-dependent signaling

scientific article published on 19 July 2010

EDA-containing fibronectin increases proliferation of embryonic stem cells

scientific article

Experimental models assessing bilirubin neurotoxicity

scientific article published on 07 September 2019

Extra domain-A fibronectin is necessary for the development of nasal remodeling in chronic allergen-induced rhinitis

scientific article

Fibronectin extra domain A stabilises atherosclerotic plaques in apolipoprotein E and in LDL-receptor-deficient mice.

scientific article

Fibronectin splice variants: understanding their multiple roles in health and disease using engineered mouse models.

scientific article published on July 2011

Generation of Ugt1-deficient murine liver cell lines using TALEN technology

scientific article

Human liver stem cells express UGT1A1 and improve phenotype of immunocompromised Crigler Najjar syndrome type I mice

scientific article published on 21 January 2020

Hypertension in beta-adducin-deficient mice

scientific article published on 01 September 2000

Hypertension-linked decrease in the expression of brain gamma-adducin

scientific article

Identification of 3' gene ends using transcriptional and genomic conservation across vertebrates

scientific article

Impaired motor coordination in mice lacking the EDA exon of the fibronectin gene.

scientific article published on 12 April 2005

Impairment of enzymatic antioxidant defenses is associated with bilirubin-induced neuronal cell death in the cerebellum of Ugt1 KO mice

scientific article

Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model.

scientific article published on 24 March 2017

Lack of Fibronectin Extra Domain A Alternative Splicing Exacerbates Endothelial Dysfunction in Diabetes

scientific article published on 29 November 2016

Life-long correction of hyperbilirubinemia with a neonatal liver-specific AAV-mediated gene transfer in a lethal mouse model of Crigler-Najjar Syndrome

scientific article published on September 2014

Long-distance regulation of Add2 pre-mRNA3'end processing

scientific article published on 14 February 2013

Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1-/- lethal mouse model of neonatal hyperbilirubinemia.

scientific article published on 25 December 2016

Preclinical Development of an AAV8-hUGT1A1 Vector for the Treatment of Crigler-Najjar Syndrome

scientific article published on 31 December 2018

Promoterless gene targeting without nucleases rescues lethality of a Crigler-Najjar syndrome mouse model

scientific article published on 27 July 2017

Prothrombotic effects of fibronectin isoforms containing the EDA domain

scientific article published on 08 November 2007

Recipient‐derived EDA fibronectin promotes cardiac allograft fibrosis

scientific article published on 04 January 2012

Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan

scientific journal article

Regulation of fibronectin EDA exon alternative splicing: possible role of RNA secondary structure for enhancer display.

scientific article

Regulation of the fibronectin EDA exon alternative splicing. Cooperative role of the exonic enhancer element and the 5' splicing site

scientific article published on October 1998

Regulation of the human apolipoprotein AIV gene expression in transgenic mice

scientific article published on 01 February 1999

Repeated AAV-mediated gene transfer by serotype switching enables long-lasting therapeutic levels of hUgt1a1 enzyme in a mouse model of Crigler-Najjar Syndrome Type I.

scientific article published on 14 August 2017

Rescue of bilirubin‐induced neonatal lethality in a mouse model of Crigler‐Najjar syndrome type I by AAV9‐mediated gene transfer

scientific article published on November 17, 2011

Stam2 expression pattern during embryo development

scientific article

TDP-43 regulates β-adducin (Add2) transcript stability.

scientific article published on January 2014

The CRE-binding factor ATF-2 facilitates the occupation of the CCAAT box in the fibronectin gene promoter

scientific article published on 01 July 1993

The erythrocyte skeletons of beta-adducin deficient mice have altered levels of tropomyosin, tropomodulin and EcapZ.

scientific article published in October 2004

The extra domain A of fibronectin is essential for allergen-induced airway fibrosis and hyperresponsiveness in mice

scientific article published on 17 December 2010

Unexpected rescue of alpha-synuclein and multimerin1 deletion in C57BL/6JOlaHsd mice by beta-adducin knockout

scientific article published in April 2006

beta-adducin (Add2) KO mice show synaptic plasticity, motor coordination and behavioral deficits accompanied by changes in the expression and phosphorylation levels of the alpha- and gamma-adducin subunits

scientific article published on 22 September 2009