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List of works by John Kevin Fallon

A monolayer of primary colonic epithelium generated on a scaffold with a gradient of stiffness for drug transport studies

scientific article published on 30 October 2018

Absolute quantification of human uridine-diphosphate glucuronosyl transferase (UGT) enzyme isoforms 1A1 and 1A6 by tandem LC-MS.

scientific article

Action of MDMA (ecstasy) and its metabolites on arginine vasopressin release.

scientific article published in June 2002

Antiretroviral Drug Concentrations in Lymph Nodes: A Cross-Species Comparison of the Effect of Drug Transporter Expression, Viral Infection, and Sex in Humanized Mice, Nonhuman Primates, and Humans

scientific article published on 24 June 2019

Antiretroviral penetration and drug transporter concentrations in the spleens of three preclinical animal models and humans

scientific article published on 13 July 2020

Arginine vasopressin release in response to the administration of 3,4-methylenedioxymethamphetamine ("ecstasy"): is metabolism a contributory factor?

scientific article published in October 2001

Candida albicans in urine can produce testosterone: impact on the testosterone/epitestosterone sports drug test.

scientific article published in October 2002

Characterization of biomolecular nanoconjugates by high-throughput delivery and spectroscopic difference.

scientific article

Combinational delivery of hydrophobic and hydrophilic anticancer drugs in single nanoemulsions to treat MDR in cancer

scientific article

Disulfide bond bridge insertion turns hydrophobic anticancer prodrugs into self-assembled nanomedicines

scientific article

Effects of direct spiking of silicone oil into a model pMDI formulation

scientific article published on 26 May 2012

Efflux transporter breast cancer resistance protein dominantly expresses on the membrane of red blood cells, hinders partitioning of its substrates into the cells, and alters drug-drug interaction profiles

scientific article

Evaluation of human primary intestinal monolayers for drug metabolizing capabilities

scientific article published on 04 November 2019

Extreme low dose of 5-fluorouracil reverses MDR in cancer by sensitizing cancer associated fibroblasts and down-regulating P-gp

scientific article

Factors Affecting Interindividual Variability of Hepatic UGT2B17 Protein Expression Examined Using a Novel Specific Monoclonal Antibody

scientific article published on 28 February 2019

Immunization of guinea pigs with novel hepatitis B antigen as nanoparticle aggregate powders administered by the pulmonary route

scientific article published on 24 April 2010

Low-dose MDMA ("ecstasy") induces vasopressin secretion

scientific article published in June 1998

Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking

article

Multimodal analysis of drug transporter expression in gastrointestinal tissue

scientific article published on 05 June 2017

Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential.

scientific article

New mouse xenograft model modulated by tumor-associated fibroblasts for human multi-drug resistance in cancer.

scientific article

Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake

scientific article published on 26 November 2019

Pharmacokinetics of sequential doses of capreomycin powder for inhalation in guinea pigs

scientific article published on 13 February 2012

Programmed Hydrolysis in Designing Paclitaxel Prodrug for Nanocarrier Assembly.

scientific article published on 13 July 2015

Pulmonary immunization of guinea pigs with diphtheria CRM-197 antigen as nanoparticle aggregate dry powders enhance local and systemic immune responses.

scientific article

Quantification of Four Efflux Drug Transporters in Liver and Kidney Across Species Using Targeted Quantitative Proteomics by Isotope Dilution NanoLC-MS/MS.

scientific article published on 29 June 2016

Quantification of human uridine-diphosphate glucuronosyl transferase 1A isoforms in liver, intestine, and kidney using nanobore liquid chromatography-tandem mass spectrometry.

scientific article published on 5 December 2011

Quantification of membrane transporter proteins in human lung and immortalized cell lines using targeted quantitative proteomic analysis by isotope dilution nanoLC-MS/MS.

scientific article published on 22 February 2018

Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase (UGT) Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity

scientific article

Quantitative profiling of human renal UDP-glucuronosyltransferases and glucuronidation activity: a comparison of normal and tumoral kidney tissues

scientific article

Scaling factors for the in vitro-in vivo extrapolation (IV-IVE) of renal drug and xenobiotic glucuronidation clearance

scientific article published on 25 January 2016

Targeted precise quantification of 12 human recombinant uridine-diphosphate glucuronosyl transferase 1A and 2B isoforms using nano-ultra-high-performance liquid chromatography/tandem mass spectrometry with selected reaction monitoring

scientific article published on 17 September 2013

Targeted quantitative proteomic analysis of drug metabolizing enzymes and transporters by nano LC-MS/MS in the sandwich cultured human hepatocyte model

scientific article published on 31 May 2019

Targeted quantitative proteomics for the analysis of 14 UGT1As and -2Bs in human liver using NanoUPLC-MS/MS with selected reaction monitoring

scientific article

The Effect of Surfactant on Paclitaxel Nanocrystals: An In Vitro and In Vivo Study.

scientific article published on January 2016

The effect of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and its metabolites on neurohypophysial hormone release from the isolated rat hypothalamus

scientific article

Theranostic nanoemulsions: codelivery of hydrophobic drug and hydrophilic imaging probe for cancer therapy and imaging.

scientific article

UGT concentrations in human rectal tissue after multidose, oral curcumin

scientific article published on 23 February 2016

Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein

scientific article

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