List of works - John Alumasa

Antimalarial drugs and heme in detergent micelles: An NMR study.

scientific article published on 27 January 2009

Antiplasmodial and antiproliferative pseudoguaianolides of Athroisma proteiforme from the Madagascar Dry Forest. ⬇️

scientific article

Antiproliferative and antimalarial anthraquinones of Scutia myrtina from the Madagascar forest. ⬇️

scientific article published on 20 February 2009

Cell-based assay to identify inhibitors of the Hfq-sRNA regulatory pathway.

scientific article

Clicking on trans-translation drug targets

scientific article

Cytostatic versus cytocidal activities of chloroquine analogues and inhibition of hemozoin crystal growth.

scientific article published on 31 October 2012

Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay

scientific article

Inhibitors of Ribosome Rescue Arrest Growth of Francisella tularensis at All Stages of Intracellular Replication.

scientific article published on 07 March 2016

Overcoming drug resistance to heme-targeted antimalarials by systematic side chain variation of 7-chloro-4-aminoquinolines

scientific article published on 18 March 2008

Pathogen-specific antimicrobials engineered de novo through membrane-protein biomimicry

scientific article published on 04 January 2021

Pharmacological inhibition of the ClpXP protease increases bacterial susceptibility to host cathelicidin antimicrobial peptides and cell envelope-active antibiotics

scientific article published on 17 January 2012

Quinine and chloroquine differentially perturb heme monomer-dimer equilibrium

scientific article published on 6 June 2008

Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells.

scientific article

Small molecule inhibitors of trans -translation have broad-spectrum antibiotic activity ⬇️

scientific article published on June 3, 2013

Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas

scientific article published on 12 November 2008

Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain.

scientific article published on 08 August 2009

Tetrazole-Based trans-Translation Inhibitors Kill Bacillus anthracis Spores to Protect Host Cells

scientific article

The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.

scientific article

The potential of trans-translation inhibitors as antibiotics

scientific article published in October 2013

trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo

scientific article published on 19 March 2021

List of works by John Alumasa

Antimalarial drugs and heme in detergent micelles: An NMR study.

Antiplasmodial and antiproliferative pseudoguaianolides of Athroisma proteiforme from the Madagascar Dry Forest. ⬇️

Antiproliferative and antimalarial anthraquinones of Scutia myrtina from the Madagascar forest. ⬇️

Cell-based assay to identify inhibitors of the Hfq-sRNA regulatory pathway.

Clicking on trans-translation drug targets

Cytostatic versus cytocidal activities of chloroquine analogues and inhibition of hemozoin crystal growth.

Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay

Inhibitors of Ribosome Rescue Arrest Growth of Francisella tularensis at All Stages of Intracellular Replication.

Overcoming drug resistance to heme-targeted antimalarials by systematic side chain variation of 7-chloro-4-aminoquinolines

Pathogen-specific antimicrobials engineered de novo through membrane-protein biomimicry

Pharmacological inhibition of the ClpXP protease increases bacterial susceptibility to host cathelicidin antimicrobial peptides and cell envelope-active antibiotics

Quinine and chloroquine differentially perturb heme monomer-dimer equilibrium

Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells.

Small molecule inhibitors of trans -translation have broad-spectrum antibiotic activity ⬇️

Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas

Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain.

Tetrazole-Based trans-Translation Inhibitors Kill Bacillus anthracis Spores to Protect Host Cells

The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.

The potential of trans-translation inhibitors as antibiotics

trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo