Search filters

List of works by Raymond Chuen-Chung Chang

1-phenyl 2-thiourea (PTU) activates autophagy in zebrafish embryos

scientific article published on 14 April 2020

A breach in the scaffold: the possible role of cytoskeleton dysfunction in the pathogenesis of major depression

scientific article published on 17 September 2012

A novel effect of an opioid receptor antagonist, naloxone, on the production of reactive oxygen species by microglia: a study by electron paramagnetic resonance spectroscopy.

scientific article

A pro-drug of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) prevents differentiated SH-SY5Y cells from toxicity induced by 6-hydroxydopamine

scientific article

A reciprocal relationship between reactive oxygen species and mitochondrial dynamics in neurodegeneration

scientific article published on 12 August 2017

Activation of the Nrf2/HO-1 antioxidant pathway contributes to the protective effects of Lycium barbarum polysaccharides in the rodent retina after ischemia-reperfusion-induced damage

scientific article published on 6 January 2014

Advances in Alzheimer's disease: from bench to bedside

scientific article published on 19 February 2015

Altered Expression Levels of MicroRNA-132 and Nurr1 in Peripheral Blood of Parkinson's Disease: Potential Disease Biomarkers

scientific article published on 01 April 2019

Ammon's Horn 2 (CA2) of the Hippocampus: A Long-Known Region with a New Potential Role in Neurodegeneration

scientific article published on 05 June 2018

Antagonizing beta-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum

scientific article published on 13 November 2007

Anti-aging herbal medicine--how and why can they be used in aging-associated neurodegenerative diseases?

scientific article published on 13 October 2009

Application of Acupuncture to Attenuate Immune Responses and Oxidative Stress in Postoperative Cognitive Dysfunction: What Do We Know So Far?

scientific article published on 13 February 2020

BAD and Bcl-2 regulation are early events linking neuronal endoplasmic reticulum stress to mitochondria-mediated apoptosis

scientific article published in December 2002

Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury

scientific article published on 23 August 2013

Beneficial effects of cinnamon proanthocyanidins on the formation of specific advanced glycation endproducts and methylglyoxal-induced impairment on glucose consumption

scientific article

Beta-amyloid peptides induces neuronal apoptosis via a mechanism independent of unfolded protein responses

scientific article published in May 2006

Borneol for Regulating the Permeability of the Blood-Brain Barrier in Experimental Ischemic Stroke: Preclinical Evidence and Possible Mechanism

scientific article published on 04 February 2019

Bringing CLARITY to the human brain: visualization of Lewy pathology in three dimensions.

scientific article published on 3 November 2015

Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities

scientific article published on 05 August 2009

Characterization of polysaccharides from the flowers of Nerium indicum and their neuroprotective effects.

scientific article

Characterization of the effects of anti-aging medicine Fructus lycii on beta-amyloid peptide neurotoxicity.

scientific article

Characterizing the neuroprotective effects of alkaline extract of Lycium barbarum on beta-amyloid peptide neurotoxicity

scientific article published on 6 May 2007

Cigarette smoking accelerated brain aging and induced pre-Alzheimer-like neuropathology in rats

scientific article

Cognitive impairment in Irritable Bowel Syndrome (IBS): A systematic review

scientific article published on 28 May 2019

Contribution of anion transporters to the acidosis-induced swelling and intracellular acidification of glial cells.

scientific article

Could PKR inhibition modulate human neurodegeneration?

scientific article published in October 2009

Current neuroimaging techniques in Alzheimer's disease and applications in animal models

scientific article

Cytokines: how important are they in mediating sickness?

scientific article

Cytoprotective effects of Lycium barbarum against reducing stress on endoplasmic reticulum.

scientific article published on June 2006

Dexmedetomidine directly increases tau phosphorylation

scientific article published in January 2015

Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription

scientific journal article

Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity

scientific article

Differential effects of propofol and dexmedetomidine on neuroinflammation induced by systemic endotoxin lipopolysaccharides in adult mice

scientific article published on 31 May 2019

Differential expression of galanin in the cholinergic basal forebrain of patients with Lewy body disorders

scientific article

Dissecting the Role of Anti-ganglioside Antibodies in Guillain-Barré Syndrome: an Animal Model Approach.

scientific article published on 15 September 2015

Distinct relaxation timescales of neurites revealed by rate-dependent indentation, relaxation and micro-rheology tests

scientific article published on 01 January 2019

Editorial

Effect of Continuous Propofol Infusion in Rat on Tau Phosphorylation with or without Temperature Control

scientific article

Effect of Lycium barbarum (Wolfberry) on alleviating axonal degeneration after partial optic nerve transection

scientific article published on 23 January 2015

Effect of Lycium barbarum Polysaccharides on the expression of endothelin-1 and its receptors in an ocular hypertension model of rat glaucoma.

scientific article

Effect of Mild and Moderate Hypothermia on the Acidosis-Induced Swelling of Glial Cells ⬇️

scientific article published on January 1, 1997

Effect of α-Trinositol on Swelling and Damage of Glial Cells by Lactacidosis and Glutamate ⬇️

scientific article published on January 1, 1997

Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research

scientific article

Effects of corticosterone and amyloid-beta on proteins essential for synaptic function: implications for depression and Alzheimer's disease

scientific article published on 6 August 2013

Effects of tumor necrosis factor alpha on taurine uptake in cultured rat astrocytes

scientific article published in March 2001

Erratum: Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model

scientific article

Free of acrylamide sodium dodecyl sulphate (SDS)-based tissue clearing (FASTClear): a novel protocol of tissue clearing for three-dimensional visualization of human brain tissues.

scientific article published on 14 September 2016

From small to big molecules: how do we prevent and delay the progression of age-related neurodegeneration?

scientific article published on January 2012

Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy.

scientific article published on 19 June 2013

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

High concentrations of extracellular potassium enhance bacterial endotoxin lipopolysaccharide-induced neurotoxicity in glia–neuron mixed cultures

article

Identification of "sarsasapogenin-aglyconed" timosaponins as novel Aβ-lowering modulators of amyloid precursor protein processing.

scientific article published on 22 January 2016

Identification of Novel Key Molecules Involved in Spatial Memory Impairment in Triple Transgenic Mice of Alzheimer's Disease

scientific article published on 22 June 2016

Identification of the key molecules involved in chronic copper exposure-aggravated memory impairment in transgenic mice of Alzheimer's disease using proteomic analysis

scientific article published on January 2015

Immune modulatory effects of Prunella vulgaris L.

scientific article

Immune modulatory effects of neural cell adhesion molecules on lipopolysaccharide-induced nitric oxide production by cultured glia

scientific article published in September 2000

In vitro attenuation of acrolein-induced toxicity by phloretin, a phenolic compound from apple ⬇️

scientific article published on June 29, 2012

Influence of neurons on lipopolysaccharide-stimulated production of nitric oxide and tumor necrosis factor-α by cultured glia

article

Intravitreous injection for establishing ocular diseases model

scientific article published on October 2007

Investigating degeneration of the retina in young and aged tau P301L mice

scientific article published on 12 January 2015

Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2alpha in neuronal degeneration

scientific article published in December 2002

Is exercise a senolytic medicine? A systematic review

scientific article published on 30 December 2020

Ketamine and selective activation of parvalbumin interneurons inhibit stress-induced dendritic spine elimination

scientific article published on 10 December 2018

Laser-induced chronic ocular hypertension model on SD rats

scientific article

Leukocyte invasion of the brain after peripheral trauma in zebrafish (Danio rerio)

scientific article published in 2022

Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal mongolian gerbil (Meriones unguiculatus).

scientific article published on 5 November 2010

Links between the Brain and Retina: The Effects of Cigarette Smoking-Induced Age-Related Changes in Alzheimer's Disease and Macular Degeneration

scientific article published on 27 July 2016

Long-term increase of Sp-1 transcription factors in the hippocampus after kainic acid treatment.

scientific article

Low molecular weight Abeta induces collapse of endoplasmic reticulum

scientific article published on 5 February 2009

Lycium barbarum (wolfberry) reduces secondary degeneration and oxidative stress, and inhibits JNK pathway in retina after partial optic nerve transection.

scientific article

Lycium barbarum Extracts Protect the Brain from Blood-Brain Barrier Disruption and Cerebral Edema in Experimental Stroke ⬇️

scientific article published on March 16, 2012

Lycium barbarum polysaccharides promotes in vivo proliferation of adult rat retinal progenitor cells

scientific article published on December 2015

Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury

scientific article

Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model

scientific article

Metabolic changes in the anterior and posterior cingulate cortices of the normal aging brain: proton magnetic resonance spectroscopy study at 3 T

scientific article

Metabolic phenotype of the healthy rodent model using in-vial extraction of dried serum, urine, and cerebrospinal fluid spots

scientific article published on 25 July 2013

Micro-dissection of rat brain for RNA or protein extraction from specific brain region

scientific article published on 30 August 2007

Modulation of calcium/calmodulin kinase-II provides partial neuroprotection against beta-amyloid peptide toxicity

scientific article published in April 2004

Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model

scientific article published on June 2009

Modulation of mitochondrial calcium as a pharmacological target for Alzheimer's disease

scientific article published on 27 May 2010

Modulation of morphological changes of microglia and neuroprotection by monocyte chemoattractant protein-1 in experimental glaucoma

scientific article published on January 2010

Modulation of neuroimmune responses on glia in the central nervous system: implication in therapeutic intervention against neuroinflammation

scientific article published on October 2009

Morphometric analyses of retinal sections

scientific article published on 19 February 2012

Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina?

scientific article published on 11 May 2011

Neuroinflammation and Aβ accumulation linked to systemic inflammation are decreased by genetic PKR down-regulation

scientific article published on 17 February 2015

Neurons reduce glial responses to lipopolysaccharide (LPS) and prevent injury of microglial cells from over-activation by LPS.

scientific article published in February 2001

Neuropathology of cigarette smoking

scientific article

Neuroprotection of Coenzyme Q10 in Neurodegenerative Diseases

scientific article published on 26 August 2015

Neuroprotective effects of Lycium barbarum Lynn on protecting retinal ganglion cells in an ocular hypertension model of glaucoma

scientific article

Neuroprotective effects of anti-aging oriental medicine Lycium barbarum against beta-amyloid peptide neurotoxicity

scientific article

Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine-induced toxicity in rat cortical neurons

scientific article published in January 2010

New polysaccharide from Nerium indicum protects neurons via stress kinase signaling pathway

scientific article

Novel neuroprotective effects of the aqueous extracts from Verbena officinalis Linn.

scientific article published on 6 January 2006

Nucleus basalis of Meynert revisited: anatomy, history and differential involvement in Alzheimer's and Parkinson's disease

scientific article

Nutraceuticals and their preventive or potential therapeutic value in Parkinson's disease

scientific article published on 22 May 2012

Optimized Tissue Clearing Minimizes Distortion and Destruction During Tissue Delipidation

scientific article published on 26 October 2020

Oral feeding of minocycline attenuates glial activation and reductions of tau and drebrin in response to systemically injected cytokines

scientific article published in June 2016

Oxyresveratrol exerts ATF4- and Grp78-mediated neuroprotection against endoplasmic reticulum stress in experimental Parkinson's disease

scientific article published on 17 May 2019

PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load

scientific article

Palmitate and Stearate are Increased in the Plasma in a 6-OHDA Model of Parkinson's Disease

scientific article published on 13 February 2019

Polysaccharides from Wolfberry Prevents Corticosterone-Induced Inhibition of Sexual Behavior and Increases Neurogenesis ⬇️

scientific article published on April 16, 2012

Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons.

scientific article published in December 2009

Post-transcriptional inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by Gö6976 in murine microglia

scientific article published on 01 June 2000

Protection of retinal ganglion cells and retinal vasculature by Lycium barbarum polysaccharides in a mouse model of acute ocular hypertension

scientific article

Protective effects of pinostilbene, a resveratrol methylated derivative, against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells

scientific article

Protective effects of testosterone on presynaptic terminals against oligomeric β-amyloid peptide in primary culture of hippocampal neurons

scientific article published on 18 June 2014

Quantitative Analysis of Brain Edema Resolution into the Cerebral Ventricles and Subarachnoid Space ⬇️

scientific article published on 01 January 1997

Rationalisation and Validation of an Acrylamide-Free Procedure in Three-Dimensional Histological Imaging

scientific article

Reduction by naloxone of lipopolysaccharide-induced neurotoxicity in mouse cortical neuron–glia co-cultures

article

Research advances on the usage of traditional Chinese medicine for neuroprotection in glaucoma

scientific article published on July 2013

Retrograde labeling of retinal ganglion cells by application of fluoro-gold on the surface of superior colliculus

scientific article published on 17 June 2008

Review: tauopathy in the retina and optic nerve: does it shadow pathological changes in the brain? ⬇️

scientific article published on November 12, 2012

Role of Calcium Ions in Acidosis-Induced Glial Swelling ⬇️

scientific article published on January 1, 1997

Role of Protein Kinase C in Acidosis Induced Glial Swelling —Current Understanding ⬇️

scientific article published on January 1, 1997

Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3β pathways

scientific article published on 29 April 2015

Sickness: From the focus on cytokines, prostaglandins, and complement factors to the perspectives of neurons

scientific article published on 05 August 2015

Significance of molecular signaling for protein translation control in neurodegenerative diseases

scientific article

Silica nanoparticles induce neurodegeneration-like changes in behavior, neuropathology, and affect synapse through MAPK activation.

scientific article published on 3 July 2018

Spatial memory impairment by TRPC1 depletion is ameliorated by environmental enrichment

scientific article

Stable expression of EBERs in immortalized nasopharyngeal epithelial cells confers resistance to apoptotic stress.

scientific article

Sulfur-containing constituents and one 1H-pyrrole-2-carboxylic acid derivative from pineapple [Ananas comosus (L.) Merr.] fruit

scientific article published on 16 September 2010

Swelling and damage of glial cells by lactacidosis and glutamate: effect of alpha-trinositol

scientific article published in August 1997

Synaptic plasticity, but not hippocampal neurogenesis, mediated the counteractive effect of wolfberry on depression in rats(1).

scientific article

Technical note: a new model for quantitative analysis of brain oedema resolution into the ventricles and the subarachnoid space

scientific article published in January 1999

Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight β-amyloid peptide

scientific article published on February 2011

The beneficial effects of physical exercise in the brain and related pathophysiological mechanisms in neurodegenerative diseases

scientific article published on 26 February 2019

The effect of Lycium barbarum on spinal cord injury, particularly its relationship with M1 and M2 macrophage in rats

scientific article

The missing link between sleep disorders and age-related dementia: recent evidence and plausible mechanisms

scientific article published on 10 February 2017

The putative neurodegenerative links between depression and Alzheimer's disease

scientific article published on 02 May 2010

Transcriptional regulation of human FE65, a ligand of Alzheimer's disease amyloid precursor protein, by Sp1

scientific article

Up-regulation of crystallins is involved in the neuroprotective effect of wolfberry on survival of retinal ganglion cells in rat ocular hypertension model

scientific article published in May 2010

Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity

scientific article

Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far?

scientific article published on 21 August 2007

What do we need to concern in using cell line for neurotoxicology research, differentiation or disturbance of intracellular signaling?

p38 MAP kinase is involved in lipopolysaccharide-induced dopaminergic neuronal cell death in rat mesencephalic neuron-glia cultures

scientific article

Paulina is supported by:

About Paulina

Help