List of works - Nathalie Dereuddre-Bosquet

A new generation of peptide-based inhibitors targeting HIV-1 reverse transcriptase conformational flexibility

scientific article

A temperature-monitoring vaginal ring for measuring adherence

scientific article published on 12 May 2015

ATP binding cassette multidrug transporters limit the anti-HIV activity of zidovudine and indinavir in infected human macrophages.

scientific article published in August 2004

Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection

scientific article

An HIVgp41 vaccine protects CD4 central memory T cells in SHIV-infected macaques

scientific article published on 16 September 2012

Anti-HIV efficacy and biodistribution of nucleoside reverse transcriptase inhibitors delivered as squalenoylated prodrug nanoassemblies

scientific article published on 2 April 2013

Anti-Human Immunodeficiency Virus Activity of Tau Interferon in Human Macrophages: Involvement of Cellular Factors and β-Chemokines ⬇️

scientific article published on December 1, 2003

Antiretroviral treatment start-time during primary SIV(mac) infection in macaques exerts a different impact on early viral replication and dissemination

scientific article

Antiviral efficacy of favipiravir against Zika and SARS-CoV-2 viruses in non-human primates

scientific article published in 2022

Are 5'-O-carbamate-2',3'-dideoxythiacytidine new anti-HIV and anti-HBV nucleoside drugs or prodrugs?

scientific article

Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus

scientific article published on 23 March 2017

CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates

scientific article published on 4 July 2012

CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge

scientific article published on 10 October 2016

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

scientific article published in 2021

Changes in soluble factor-mediated CD8+ cell-derived antiviral activity in cynomolgus macaques infected with simian immunodeficiency virus SIVmac251: relationship to biological markers of progression

scientific article published on January 2006

Correction: Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection.

scientific article

DC Subsets Regulate Humoral Immune Responses by Supporting the Differentiation of Distinct Tfh Cells.

scientific article

Differential activity of methylene blue against erythrocytic and hepatic stages of Plasmodium.

scientific article

Differential expression levels of MRP1, MRP4, and MRP5 in response to human immunodeficiency virus infection in human macrophages

scientific article published on May 2004

Early SIV and HIV infection promotes the LILRB2/MHC-I inhibitory axis in cDCs

scientific article published on 13 November 2017

Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion

scientific article

Effectiveness of CHIKV vaccine VLA1553 demonstrated by passive transfer of human sera

scientific article published on 14 June 2022

Erratum to “Are 5′-O-Carbamate-2′,3′-dideoxythiacytidine new anti-HIV and anti-HBV nucleoside drugs or prodrugs?”[Bioorg. Med. Chem. Lett. 13 (2003) 2459]

article

Glutamate metabolism in HIV-infected macrophages: implications for the CNS.

scientific article

HIV specific responses induced in nonhuman primates with ANRS HIV-Lipo-5 vaccine combined with rMVA-HIV prime or boost immunizations

scientific article published on April 2015

HIV-1-induced production of endothelin-1 in an in vitro model of the human blood-brain barrier

scientific article published in July 2002

Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates

scientific article published on 22 July 2020

Infection of macaques after vaginal exposure to cell-associated simian immunodeficiency virus

scientific article published on August 2010

Influence of the MHC genotype on the progression of experimental SIV infection in the Mauritian cynomolgus macaque

scientific article published on 14 January 2011

Inhibition of HIV-1 replication by cell-penetrating peptides binding Rev.

scientific article

Inhibitors of CTP biosynthesis potentiate the anti-human immunodeficiency virus type 1 activity of 3TC in activated peripheral blood mononuclear cells

scientific article published in January 2004

Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection

scientific article (publication date: July 2014)

Intradermal injection of an anti-Langerin-HIVGag fusion vaccine targets epidermal Langerhans cells in nonhuman primates and can be tracked in vivo

scientific article published on 17 December 2015

Involvement of IL-6 in the anti-human immunodeficiency virus activity of IFN-tau in human macrophages

scientific article

Kinetics of Lymphocyte Proliferation during Primary Immune Response in Macaques Infected with Pathogenic Simian Immunodeficiency Virus SIVmac251: Preliminary Report of the Effect of Early Antiviral Therapy ⬇️

scientific article published on December 1, 2003

Laser capture microdissection enables transcriptomic analysis of dividing and quiescent liver stages of Plasmodium relapsing species

scientific article

Long-term control of simian immunodeficiency virus (SIV) in cynomolgus macaques not associated with efficient SIV-specific CD8+ T-cell responses

scientific article

Macrophage activation and human immunodeficiency virus infection: HIV replication directs macrophages towards a pro-inflammatory phenotype while previous activation modulates macrophage susceptibility to infection and viral production

scientific article published on 29 March 2006

Macrophage- and neutrophil-derived TNF-α instructs skin langerhans cells to prime antiviral immune responses

scientific article

Metabolism evaluation of biomimetic prodrugs by in vitro models and mass spectrometry.

scientific article published on 23 May 2009

MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaques

scientific article (publication date: 2012)

Modified Vaccinia Virus Ankara Vector Induces Specific Cellular and Humoral Responses in the Female Reproductive Tract, the Main HIV Portal of Entry

scientific article

Molecular and Cellular Dynamics in the Skin, the Lymph Nodes, and the Blood of the Immune Response to Intradermal Injection of Modified Vaccinia Ankara Vaccine.

scientific article

Nerve growth factor stimulation promotes CXCL-12 attraction of monocytes but decreases human immunodeficiency virus replication in attracted population

scientific article published on 19 November 2008

Note on the formulation of thermosensitive and mucoadhesive vaginal hydrogels containing the miniCD4 M48U1 as anti-HIV-1 microbicide

scientific article

OMIP-016: Characterization of antigen-responsive macaque and human T-cells.

scientific article published on 26 November 2012

Optimization of HIV-1 Envelope DNA Vaccine Candidates within Three Different Animal Models, Guinea Pigs, Rabbits and Cynomolgus Macaques

scientific article published on 19 July 2013

Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures

scientific article published on 9 February 2014

Plasmacytoid dendritic cell dynamics tune interferon-alfa production in SIV-infected cynomolgus macaques

scientific article

Potent nonclassical nucleoside antiviral drugs based on the N,N-diarylformamidine concept

scientific article published on February 2004

Regulated Expression of Sodium‐dependent Glutamate Transporters and Synthetase: a Neuroprotective Role for Activated Microglia and Macrophages in HIV Infection? ⬇️

scientific article published on April 1, 2003

Semen CD4+ T cells and macrophages are productively infected at all stages of SIV infection in macaques

scientific article

Seminal Plasma Exposures Strengthen Vaccine Responses in the Female Reproductive Tract Mucosae

article

Seminal Simian Immunodeficiency Virus in Chronically Infected Cynomolgus Macaques Is Dominated by Virus Originating from Multiple Genital Organs.

scientific article published on 29 June 2018

Squalenoyl nanomedicines as potential therapeutics

scientific article published on November 2006

Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection

scientific article published on 11 January 2018

Structure-activity relationships in platelet-activating factor. 12. Synthesis and biological evaluation of platelet-activating factor antagonists with anti-HIV-1 activity

scientific article published in December 2004

Structure-activity relationships in platelet-activating factor. Part 13: synthesis and biological evaluation of piperazine derivatives with dual anti-PAF and anti-HIV-1 or pure antiretroviral activity

scientific article published on 8 August 2006

Structure-activity relationships in platelet-activating factor. Part 14: synthesis and biological evaluation of piperazine derivatives with dual anti-PAF and anti-HIV-1 activity

scientific article published in December 2006

Superior Efficacy of a Human Immunodeficiency Virus Vaccine Combined with Antiretroviral Prevention in Simian-Human Immunodeficiency Virus-Challenged Nonhuman Primates

scientific article published on 23 March 2016

Synthesis and biological evaluation in human monocyte-derived macrophages of N-(N-acetyl-L-cysteinyl)-S-acetylcysteamine analogues with potent antioxidant and anti-HIV activities

scientific article published in March 2004

Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cells

scientific article published on 2 January 2012

The Frequencies of Immunosuppressive Cells in Adipose Tissue Differ in Human, Non-human Primate, and Mouse Models

The expression of P-glycoprotein and cellular kinases is modulated at the transcriptional level by infection and highly active antiretroviral therapy in a primate model of AIDS.

scientific article

Towards a vaccine against AIDS.

scientific article

Towards an in vitro model of Plasmodium hypnozoites suitable for drug discovery

scientific article

Vaccination with the Conserved Caveolin-1 Binding Motif in Human Immunodeficiency Virus Type 1 Glycoprotein gp41 Delays the Onset of Viral Infection and Provides Partial Protection in Simian/Human Immunodeficiency Virus-Challenged Cynomolgus Macaques

scholarly article by Ara G Hovanessian et al published 15 September 2018 in Journal of Virology

Whole genome sequencing in the search for genes associated with the control of SIV infection in the Mauritian macaque model.

scientific article

List of works by Nathalie Dereuddre-Bosquet

A new generation of peptide-based inhibitors targeting HIV-1 reverse transcriptase conformational flexibility

A temperature-monitoring vaginal ring for measuring adherence

ATP binding cassette multidrug transporters limit the anti-HIV activity of zidovudine and indinavir in infected human macrophages.

Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection

An HIVgp41 vaccine protects CD4 central memory T cells in SHIV-infected macaques

Anti-HIV efficacy and biodistribution of nucleoside reverse transcriptase inhibitors delivered as squalenoylated prodrug nanoassemblies

Anti-Human Immunodeficiency Virus Activity of Tau Interferon in Human Macrophages: Involvement of Cellular Factors and β-Chemokines ⬇️

Antiretroviral treatment start-time during primary SIV(mac) infection in macaques exerts a different impact on early viral replication and dissemination

Antiviral efficacy of favipiravir against Zika and SARS-CoV-2 viruses in non-human primates

Are 5'-O-carbamate-2',3'-dideoxythiacytidine new anti-HIV and anti-HBV nucleoside drugs or prodrugs?

Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus

CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates

CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

Changes in soluble factor-mediated CD8+ cell-derived antiviral activity in cynomolgus macaques infected with simian immunodeficiency virus SIVmac251: relationship to biological markers of progression

Correction: Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection.

DC Subsets Regulate Humoral Immune Responses by Supporting the Differentiation of Distinct Tfh Cells.

Differential activity of methylene blue against erythrocytic and hepatic stages of Plasmodium.

Differential expression levels of MRP1, MRP4, and MRP5 in response to human immunodeficiency virus infection in human macrophages

Early SIV and HIV infection promotes the LILRB2/MHC-I inhibitory axis in cDCs

Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion

Effectiveness of CHIKV vaccine VLA1553 demonstrated by passive transfer of human sera

Erratum to “Are 5′-O-Carbamate-2′,3′-dideoxythiacytidine new anti-HIV and anti-HBV nucleoside drugs or prodrugs?”[Bioorg. Med. Chem. Lett. 13 (2003) 2459]

Glutamate metabolism in HIV-infected macrophages: implications for the CNS.

HIV specific responses induced in nonhuman primates with ANRS HIV-Lipo-5 vaccine combined with rMVA-HIV prime or boost immunizations

HIV-1-induced production of endothelin-1 in an in vitro model of the human blood-brain barrier

Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates

Infection of macaques after vaginal exposure to cell-associated simian immunodeficiency virus

Influence of the MHC genotype on the progression of experimental SIV infection in the Mauritian cynomolgus macaque

Inhibition of HIV-1 replication by cell-penetrating peptides binding Rev.

Inhibitors of CTP biosynthesis potentiate the anti-human immunodeficiency virus type 1 activity of 3TC in activated peripheral blood mononuclear cells

Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection

Intradermal injection of an anti-Langerin-HIVGag fusion vaccine targets epidermal Langerhans cells in nonhuman primates and can be tracked in vivo

Involvement of IL-6 in the anti-human immunodeficiency virus activity of IFN-tau in human macrophages

Kinetics of Lymphocyte Proliferation during Primary Immune Response in Macaques Infected with Pathogenic Simian Immunodeficiency Virus SIVmac251: Preliminary Report of the Effect of Early Antiviral Therapy ⬇️

Laser capture microdissection enables transcriptomic analysis of dividing and quiescent liver stages of Plasmodium relapsing species

Long-term control of simian immunodeficiency virus (SIV) in cynomolgus macaques not associated with efficient SIV-specific CD8+ T-cell responses

Macrophage activation and human immunodeficiency virus infection: HIV replication directs macrophages towards a pro-inflammatory phenotype while previous activation modulates macrophage susceptibility to infection and viral production

Macrophage- and neutrophil-derived TNF-α instructs skin langerhans cells to prime antiviral immune responses

Metabolism evaluation of biomimetic prodrugs by in vitro models and mass spectrometry.

MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaques

Modified Vaccinia Virus Ankara Vector Induces Specific Cellular and Humoral Responses in the Female Reproductive Tract, the Main HIV Portal of Entry

Molecular and Cellular Dynamics in the Skin, the Lymph Nodes, and the Blood of the Immune Response to Intradermal Injection of Modified Vaccinia Ankara Vaccine.

Nerve growth factor stimulation promotes CXCL-12 attraction of monocytes but decreases human immunodeficiency virus replication in attracted population

Note on the formulation of thermosensitive and mucoadhesive vaginal hydrogels containing the miniCD4 M48U1 as anti-HIV-1 microbicide

OMIP-016: Characterization of antigen-responsive macaque and human T-cells.

Optimization of HIV-1 Envelope DNA Vaccine Candidates within Three Different Animal Models, Guinea Pigs, Rabbits and Cynomolgus Macaques

Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures

Plasmacytoid dendritic cell dynamics tune interferon-alfa production in SIV-infected cynomolgus macaques

Potent nonclassical nucleoside antiviral drugs based on the N,N-diarylformamidine concept

Regulated Expression of Sodium‐dependent Glutamate Transporters and Synthetase: a Neuroprotective Role for Activated Microglia and Macrophages in HIV Infection? ⬇️

Semen CD4+ T cells and macrophages are productively infected at all stages of SIV infection in macaques

Seminal Plasma Exposures Strengthen Vaccine Responses in the Female Reproductive Tract Mucosae

Seminal Simian Immunodeficiency Virus in Chronically Infected Cynomolgus Macaques Is Dominated by Virus Originating from Multiple Genital Organs.

Squalenoyl nanomedicines as potential therapeutics

Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection

Structure-activity relationships in platelet-activating factor. 12. Synthesis and biological evaluation of platelet-activating factor antagonists with anti-HIV-1 activity

Structure-activity relationships in platelet-activating factor. Part 13: synthesis and biological evaluation of piperazine derivatives with dual anti-PAF and anti-HIV-1 or pure antiretroviral activity

Structure-activity relationships in platelet-activating factor. Part 14: synthesis and biological evaluation of piperazine derivatives with dual anti-PAF and anti-HIV-1 activity

Superior Efficacy of a Human Immunodeficiency Virus Vaccine Combined with Antiretroviral Prevention in Simian-Human Immunodeficiency Virus-Challenged Nonhuman Primates

Synthesis and biological evaluation in human monocyte-derived macrophages of N-(N-acetyl-L-cysteinyl)-S-acetylcysteamine analogues with potent antioxidant and anti-HIV activities

Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cells

The Frequencies of Immunosuppressive Cells in Adipose Tissue Differ in Human, Non-human Primate, and Mouse Models

The expression of P-glycoprotein and cellular kinases is modulated at the transcriptional level by infection and highly active antiretroviral therapy in a primate model of AIDS.

Towards a vaccine against AIDS.

Towards an in vitro model of Plasmodium hypnozoites suitable for drug discovery

Vaccination with the Conserved Caveolin-1 Binding Motif in Human Immunodeficiency Virus Type 1 Glycoprotein gp41 Delays the Onset of Viral Infection and Provides Partial Protection in Simian/Human Immunodeficiency Virus-Challenged Cynomolgus Macaques

Whole genome sequencing in the search for genes associated with the control of SIV infection in the Mauritian macaque model.