List of works - Elliot J. Androphy

A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy.

scientific article published on 9 November 2001

A mutant of human papillomavirus type 16 E6 deficient in binding alpha-helix partners displays reduced oncogenic potential in vivo.

scientific article

A novel method for selective isotope labeling of bacterially expressed proteins.

scientific article

A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.

scientific article

AMF-1/Gps2 binds p300 and enhances its interaction with papillomavirus E2 proteins

scientific article

Acetylation of Conserved Lysines in Bovine Papillomavirus E2 by p300 ⬇️

scientific article published on November 14, 2012

Acetylation of E2 by P300 Mediates Topoisomerase Entry at the Papillomavirus Replicon

scientific article published on 21 March 2019

Altered mRNA Splicing in SMN-Depleted Motor Neuron-Like Cells

scientific article

An extended inhibitory context causes skipping of exon 7 of SMN2 in spinal muscular atrophy

scientific article published on 01 March 2004

An in vivo reporter system for measuring increased inclusion of exon 7 in SMN2 mRNA: potential therapy of SMA ⬇️

scientific article (publication date: October 2001)

Anogenital warts in children. Clinical and virologic evaluation for sexual abuse

scientific article published on 01 December 1990

Association of Human Papillomavirus 16 E2 with Rad50-Interacting Protein 1 Enhances Viral DNA Replication

scientific article published on 28 December 2016

Autophagy dysregulation in cell culture and animals models of spinal muscular atrophy.

scientific article

Binding of human papillomavirus type 16 E6 to E6AP is not required for activation of hTERT

scientific article published on 17 October 2007

Bovine papillomavirus type 1 E6-induced sensitization to apoptosis is distinct from its transforming activity.

scientific article

COPI transport complexes bind to specific RNAs in neuronal cells.

scientific article published on 21 November 2012

Cellular steady-state levels of "high risk" but not "low risk" human papillomavirus (HPV) E6 proteins are increased by inhibition of proteasome-dependent degradation independent of their p53- and E6AP-binding capabilities

scientific article published in July 2002

Chloroquine Promotes Apoptosis in Melanoma Cells by Inhibiting BH3 Domain–Mediated PUMA Degradation ⬇️

scientific article published on January 31, 2013

Crystal structure of the E2 DNA-binding domain from human papillomavirus type 16: implications for its DNA binding-site selection mechanism

scientific article

Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus

scientific article published in June 2004

Determinants of stability for the E6 protein of papillomavirus type 16.

scientific article

Differential regulation of the SMN2 gene by individual HDAC proteins

scientific article

Dilysine motifs in exon 2b of SMN protein mediate binding to the COPI vesicle protein α-COP and neurite outgrowth in a cell culture model of spinal muscular atrophy ⬇️

scientific article published on May 31, 2013

Discovery, SAR and Biological Evaluation of Aryl-thiazol-piperidines as SMN Modulators

scientific article published in October 2011

Discovery, synthesis, and biological evaluation of novel SMN protein modulators

scientific article

Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds

scientific article

Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes.

scientific article

Genomic instability: Ada3 and HPV E6-acetyltransferase connections?

scientific article published on 19 December 2012

HPV Replication Regulation by Acetylation of a Conserved Lysine in the E2 Protein.

scientific article published on 15 November 2017

High throughput screening for SMA

Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated MAPK signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras.

scientific article

Human papillomavirus type 16 E6 promotes retinoblastoma protein phosphorylation and cell cycle progression.

scientific article published on December 2004

Human papillomavirus type 16 E6-enhanced susceptibility of L929 cells to tumor necrosis factor alpha correlates with increased accumulation of reactive oxygen species

scientific article published on 01 August 1999

Identification of an alpha helical motif sufficient for association with papillomavirus E6

scientific article published on 01 May 1998

Identification of novel compounds that increase SMN protein levels using an improved SMN2 reporter cell assay.

scientific article

Identification of survival motor neuron as a transcriptional activator-binding protein.

scientific article

Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathway

scientific article

Interaction of papillomavirus E2 protein with the Brm chromatin remodeling complex leads to enhanced transcriptional activation.

scientific article published on 6 December 2006

Isolation, sequence analysis and characterization of a cDNA encoding human chaperonin 10

scientific article

Kinase Activity of Fibroblast Growth Factor Receptor 3 Regulates Activity of the Papillomavirus E2 Protein

scientific article published on 2 August 2017

ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice

scientific article

Modulating role of RNA structure in alternative splicing of a critical exon in the spinal muscular atrophy genes.

scientific article published on 14 December 2006

Mutational analysis of transcriptional activation by the bovine papillomavirus type 1 E6.

scientific article published on September 1997

Opposing effects of bovine papillomavirus type 1 E6 and E7 genes on Fas-mediated apoptosis.

scientific article

PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy.

scientific article

Phosphorylation of a Conserved Tyrosine in the Papillomavirus E2 Protein Regulates Brd4 Binding and Viral Replication

scientific article published on 01 May 2019

Phosphorylation of the Bovine Papillomavirus E2 Protein on Tyrosine Regulates Its Transcription and Replication Functions

scientific article published on 2 November 2016

Phosphorylation of the Human Papillomavirus E2 Protein at Tyrosine 138 Regulates Episomal Replication

scientific article published on 29 April 2020

Polyomavirus Large T Can Support DNA Replication in Human Cells ⬇️

scientific article published on January 5, 1998

Pyk2 Regulates Human Papillomavirus Replication by Tyrosine Phosphorylation of the E2 Protein

scientific article published on 29 July 2020

SMN Modulator ML372 Increases SMN Protein Abundance, Body Weight, Lifespan, and Rescues Motor Function in SMNΔ7 SMA Mice

SMN oligomerization defect correlates with spinal muscular atrophy severity

scientific article published on 01 May 1998

Short-duration splice promoting compound enables a tunable mouse model of spinal muscular atrophy

scientific article published on 24 November 2020

Signals that dictate nuclear localization of human papillomavirus type 16 oncoprotein E6 in living cells

scientific article

Structural correlates for enhanced stability in the E2 DNA-binding domain from bovine papillomavirus

scientific article

Tax1BP1 interacts with papillomavirus E2 and regulates E2-dependent transcription and stability

scientific article

The BPV-1 E2 DNA-contact helix cysteine is required for transcriptional activation but not replication in mammalian cells.

scientific article published on March 1996

The COPI vesicle complex binds and moves with survival motor neuron within axons

scientific article

The Ewing's sarcoma protein interacts with the Tudor domain of the survival motor neuron protein

scientific journal article

The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2

scientific article

The SMC5/6 Complex Represses the Replicative Program of High-Risk Human Papillomavirus Type 31

scientific article published on 25 September 2020

The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.

scientific article

The regulation and regulatory activities of alternative splicing of the SMN gene

scientific article

The survival motor neuron protein in spinal muscular atrophy ⬇️

scientific article published on August 1, 1997

The tryptophan bridge is a critical feature of the papillomavirus E2 DNA binding domain.

scientific article

Therapeutic strategies for the treatment of spinal muscular atrophy.

scientific article

Topography of bovine papillomavirus E2 protein on the viral genome during the cell cycle.

scientific article

Transcriptional repression of E-cadherin by human papillomavirus type 16 E6.

scientific article

Two distinct regions of the BPV1 E1 replication protein interact with the activation domain of E2

scientific article published on 01 December 1999

UV-B-energy distribution in phototherapy equipment

scientific article published on 01 January 1984

Valproate and bone loss: iTRAQ proteomics show that valproate reduces collagens and osteonectin in SMA cells.

scientific article published on August 2010

X-linked inheritance of epidermodysplasia verruciformis. Genetic and virologic studies of a kindred

scientific article published in July 1985

hAda3 degradation by papillomavirus type 16 E6 correlates with abrogation of the p14ARF-p53 pathway and efficient immortalization of human mammary epithelial cells

scientific article published on 6 February 2008

List of works by Elliot J. Androphy

A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy.

A mutant of human papillomavirus type 16 E6 deficient in binding alpha-helix partners displays reduced oncogenic potential in vivo.

A novel method for selective isotope labeling of bacterially expressed proteins.

A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.

AMF-1/Gps2 binds p300 and enhances its interaction with papillomavirus E2 proteins

Acetylation of Conserved Lysines in Bovine Papillomavirus E2 by p300 ⬇️

Acetylation of E2 by P300 Mediates Topoisomerase Entry at the Papillomavirus Replicon

Altered mRNA Splicing in SMN-Depleted Motor Neuron-Like Cells

An extended inhibitory context causes skipping of exon 7 of SMN2 in spinal muscular atrophy

An in vivo reporter system for measuring increased inclusion of exon 7 in SMN2 mRNA: potential therapy of SMA ⬇️

Anogenital warts in children. Clinical and virologic evaluation for sexual abuse

Association of Human Papillomavirus 16 E2 with Rad50-Interacting Protein 1 Enhances Viral DNA Replication

Autophagy dysregulation in cell culture and animals models of spinal muscular atrophy.

Binding of human papillomavirus type 16 E6 to E6AP is not required for activation of hTERT

Bovine papillomavirus type 1 E6-induced sensitization to apoptosis is distinct from its transforming activity.

COPI transport complexes bind to specific RNAs in neuronal cells.

Cellular steady-state levels of "high risk" but not "low risk" human papillomavirus (HPV) E6 proteins are increased by inhibition of proteasome-dependent degradation independent of their p53- and E6AP-binding capabilities

Chloroquine Promotes Apoptosis in Melanoma Cells by Inhibiting BH3 Domain–Mediated PUMA Degradation ⬇️

Crystal structure of the E2 DNA-binding domain from human papillomavirus type 16: implications for its DNA binding-site selection mechanism

Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus

Determinants of stability for the E6 protein of papillomavirus type 16.

Differential regulation of the SMN2 gene by individual HDAC proteins

Dilysine motifs in exon 2b of SMN protein mediate binding to the COPI vesicle protein α-COP and neurite outgrowth in a cell culture model of spinal muscular atrophy ⬇️

Discovery, SAR and Biological Evaluation of Aryl-thiazol-piperidines as SMN Modulators

Discovery, synthesis, and biological evaluation of novel SMN protein modulators

Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds

Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes.

Genomic instability: Ada3 and HPV E6-acetyltransferase connections?

HPV Replication Regulation by Acetylation of a Conserved Lysine in the E2 Protein.

High throughput screening for SMA

Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated MAPK signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras.

Human papillomavirus type 16 E6 promotes retinoblastoma protein phosphorylation and cell cycle progression.

Human papillomavirus type 16 E6-enhanced susceptibility of L929 cells to tumor necrosis factor alpha correlates with increased accumulation of reactive oxygen species

Identification of an alpha helical motif sufficient for association with papillomavirus E6

Identification of novel compounds that increase SMN protein levels using an improved SMN2 reporter cell assay.

Identification of survival motor neuron as a transcriptional activator-binding protein.

Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathway

Interaction of papillomavirus E2 protein with the Brm chromatin remodeling complex leads to enhanced transcriptional activation.

Isolation, sequence analysis and characterization of a cDNA encoding human chaperonin 10

Kinase Activity of Fibroblast Growth Factor Receptor 3 Regulates Activity of the Papillomavirus E2 Protein

ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice

Modulating role of RNA structure in alternative splicing of a critical exon in the spinal muscular atrophy genes.

Mutational analysis of transcriptional activation by the bovine papillomavirus type 1 E6.

Opposing effects of bovine papillomavirus type 1 E6 and E7 genes on Fas-mediated apoptosis.

PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy.

Phosphorylation of a Conserved Tyrosine in the Papillomavirus E2 Protein Regulates Brd4 Binding and Viral Replication

Phosphorylation of the Bovine Papillomavirus E2 Protein on Tyrosine Regulates Its Transcription and Replication Functions

Phosphorylation of the Human Papillomavirus E2 Protein at Tyrosine 138 Regulates Episomal Replication

Polyomavirus Large T Can Support DNA Replication in Human Cells ⬇️

Pyk2 Regulates Human Papillomavirus Replication by Tyrosine Phosphorylation of the E2 Protein

SMN Modulator ML372 Increases SMN Protein Abundance, Body Weight, Lifespan, and Rescues Motor Function in SMNΔ7 SMA Mice

SMN oligomerization defect correlates with spinal muscular atrophy severity

Short-duration splice promoting compound enables a tunable mouse model of spinal muscular atrophy

Signals that dictate nuclear localization of human papillomavirus type 16 oncoprotein E6 in living cells

Structural correlates for enhanced stability in the E2 DNA-binding domain from bovine papillomavirus

Tax1BP1 interacts with papillomavirus E2 and regulates E2-dependent transcription and stability

The BPV-1 E2 DNA-contact helix cysteine is required for transcriptional activation but not replication in mammalian cells.

The COPI vesicle complex binds and moves with survival motor neuron within axons

The Ewing's sarcoma protein interacts with the Tudor domain of the survival motor neuron protein

The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2

The SMC5/6 Complex Represses the Replicative Program of High-Risk Human Papillomavirus Type 31

The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.

The regulation and regulatory activities of alternative splicing of the SMN gene

The survival motor neuron protein in spinal muscular atrophy ⬇️

The tryptophan bridge is a critical feature of the papillomavirus E2 DNA binding domain.

Therapeutic strategies for the treatment of spinal muscular atrophy.

Topography of bovine papillomavirus E2 protein on the viral genome during the cell cycle.

Transcriptional repression of E-cadherin by human papillomavirus type 16 E6.

Two distinct regions of the BPV1 E1 replication protein interact with the activation domain of E2

UV-B-energy distribution in phototherapy equipment

Valproate and bone loss: iTRAQ proteomics show that valproate reduces collagens and osteonectin in SMA cells.

X-linked inheritance of epidermodysplasia verruciformis. Genetic and virologic studies of a kindred

hAda3 degradation by papillomavirus type 16 E6 correlates with abrogation of the p14ARF-p53 pathway and efficient immortalization of human mammary epithelial cells