List of works - Robert Pascal

5(4H)-oxazolones as intermediates in the carbodiimide- and cyanamide-promoted peptide activations in aqueous solution.

scientific article

5. Prebiotic Chemistry – Biochemistry – Emergence of Life (4.4–2 Ga)

9. Life On Earth... And Elsewhere?

A Strategy for Origins of Life Research

scientific article

A computational analysis of intramolecularity in proton transfer reactions

scientific article published on 17 September 2010

A cyclic peptide mimicking the third intracellular loop of the V2 vasopressin receptor inhibits signaling through its interaction with receptor dimer and G protein

scientific journal article

A possible non-biological reaction framework for metabolic processes on early Earth

scientific article published on 01 May 2019

Activation of carboxyl group with cyanate: peptide bond formation from dicarboxylic acids.

scientific article

Active peptidic mimics of the second intracellular loop of the V(1A) vasopressin receptor are structurally related to the second intracellular rhodopsin loop: a combined 1H NMR and biochemical study

scientific article published in July 2003

Amino acid N-carboxyanhydrides: activated peptide monomers behaving as phosphate-activating agents in aqueous solution

scientific article published on 01 August 2004

An Experimental Investigation of the Evolution of Chirality in a Potential Dynamic Peptide System: N-Terminal Epimerization and Degradation into Diketopiperazine ⬇️

scientific article published on July 1, 2010

An expeditious multigram-scale synthesis of lysine dendrigraft (DGL) polymers by aqueous N-carboxyanhydride polycondensation

scientific article

Antibody-based surfaces: rapid characterization using two complementary colorimetric assays

scientific article published on 16 September 2011

Astrobiology and the Possibility of Life on Earth and Elsewhere…

scientific article published on 8 September 2015

Dendrigraft poly-L-lysine: a non-immunogenic synthetic carrier for antibody production.

scientific article published in May 2010

Design and synthesis of cyclic and linear peptide-agarose tools for baiting interacting protein partners of GPCRs

scientific article published on 11 November 2005

Diastereoselectivity in prebiotically relevant 5(4H)-oxazolone-mediated peptide couplings

scientific article published on 01 March 2014

Do enzymes bind their substrates in the ground state because of a physico-chemical requirement? ⬇️

scientific article published on 01 December 2003

Dynamic co-evolution of peptides and chemical energetics, a gateway to the emergence of homochirality and the catalytic activity of peptides.

scientific article published in February 2004

Energy flows, metabolism and translation ⬇️

scientific article published on October 27, 2011

Energy sources, self-organization, and the origin of life

scientific article published on 24 March 2010

Evolutionary importance of the intramolecular pathways of hydrolysis of phosphate ester mixed anhydrides with amino acids and peptides

scientific article published on 11 December 2014

Expeditious, potentially primordial, aminoacylation of nucleotides

scientific article published on 01 October 2005

Expression, purification and NMR characterization of the cyclic recombinant form of the third intracellular loop of the vasopressin type 2 receptor

scientific article published on 14 May 2011

Fatty acids' double role in the prebiotic formation of a hydrophobic dipeptide

scientific article published on 09 February 2016

From soup to peptides

scientific article published on 01 September 2019

How Prebiotic Chemistry and Early Life Chose Phosphate

scientific article published on 03 March 2019

How and why kinetics, thermodynamics, and chemistry induce the logic of biological evolution

scientific article published on 7 April 2017

Mapping a Systematic Ribozyme Fitness Landscape Reveals a Frustrated Evolutionary Network for Self-Aminoacylating RNA.

scientific article published on 5 April 2019

Mixed Anhydride Intermediates in the Reaction of 5(4H)-Oxazolones with Phosphate Esters and Nucleotides

scientific article published on 18 August 2016

Monitoring clinical levels of heparin in human blood samples with an indicator-displacement assay

scientific article published on 01 February 2015

Non-uniform surface charge distributions in CE: theoretical and experimental approach based on Taylor dispersion.

scientific article

On-line sample stacking of peptides in capillary electrophoresis for the study of prebiotic reactions between alpha,alpha-dialkylated amino acids and amino acid N-carboxyanhydrides.

scientific article

Pathways for the formation and evolution of peptides in prebiotic environments.

scientific article

Physicochemical Requirements Inferred for Chemical Self-Organization Hardly Support an Emergence of Life in the Deep Oceans of Icy Moons

scientific article published on 26 April 2016

Stability and its manifestation in the chemical and biological worlds

scientific article published on 14 October 2015

Structure of the third intracellular loop of the vasopressin V2 receptor and conformational changes upon binding to gC1qR.

scientific article published on 12 March 2009

The Activation of Free Dipeptides Promoted by Strong Activating Agents in Water Does not Yield Diketopiperazines.

scientific article published on 24 July 2015

The Chemical Likelihood of Ribonucleotide-α-Amino acid Copolymers as Players for Early Stages of Evolution

scientific article published on 20 February 2019

The Logic of Life

article

The Peptide Formation Mediated by Cyanate Revisited.N-Carboxyanhydrides as Accessible Intermediates in the Decomposition ofN-Carbamoylamino Acids

scientific article published on 01 June 2006

The Prebiotic C-Terminal Elongation of Peptides Can Be Initiated by N-Carbamoyl Amino Acids

scientific article published on 10 May 2017

The multifunctional protein GC1q-R interacts specifically with the i3 loop arginine cluster of the vasopressin V2 receptor.

scientific article

The origin of life: what we know, what we can know and what we will never know.

scientific article published on 06 March 2013

Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics

scientific article (publication date: 6 November 2013)

List of works by Robert Pascal

5(4H)-oxazolones as intermediates in the carbodiimide- and cyanamide-promoted peptide activations in aqueous solution.

5. Prebiotic Chemistry – Biochemistry – Emergence of Life (4.4–2 Ga)

9. Life On Earth... And Elsewhere?

A Strategy for Origins of Life Research

A computational analysis of intramolecularity in proton transfer reactions

A cyclic peptide mimicking the third intracellular loop of the V2 vasopressin receptor inhibits signaling through its interaction with receptor dimer and G protein

A possible non-biological reaction framework for metabolic processes on early Earth

Activation of carboxyl group with cyanate: peptide bond formation from dicarboxylic acids.

Active peptidic mimics of the second intracellular loop of the V(1A) vasopressin receptor are structurally related to the second intracellular rhodopsin loop: a combined 1H NMR and biochemical study

Amino acid N-carboxyanhydrides: activated peptide monomers behaving as phosphate-activating agents in aqueous solution

An Experimental Investigation of the Evolution of Chirality in a Potential Dynamic Peptide System: N-Terminal Epimerization and Degradation into Diketopiperazine ⬇️

An expeditious multigram-scale synthesis of lysine dendrigraft (DGL) polymers by aqueous N-carboxyanhydride polycondensation

Antibody-based surfaces: rapid characterization using two complementary colorimetric assays

Astrobiology and the Possibility of Life on Earth and Elsewhere…

Dendrigraft poly-L-lysine: a non-immunogenic synthetic carrier for antibody production.

Design and synthesis of cyclic and linear peptide-agarose tools for baiting interacting protein partners of GPCRs

Diastereoselectivity in prebiotically relevant 5(4H)-oxazolone-mediated peptide couplings

Do enzymes bind their substrates in the ground state because of a physico-chemical requirement? ⬇️

Dynamic co-evolution of peptides and chemical energetics, a gateway to the emergence of homochirality and the catalytic activity of peptides.

Energy flows, metabolism and translation ⬇️

Energy sources, self-organization, and the origin of life

Evolutionary importance of the intramolecular pathways of hydrolysis of phosphate ester mixed anhydrides with amino acids and peptides

Expeditious, potentially primordial, aminoacylation of nucleotides

Expression, purification and NMR characterization of the cyclic recombinant form of the third intracellular loop of the vasopressin type 2 receptor

Fatty acids' double role in the prebiotic formation of a hydrophobic dipeptide

From soup to peptides

How Prebiotic Chemistry and Early Life Chose Phosphate

How and why kinetics, thermodynamics, and chemistry induce the logic of biological evolution

Mapping a Systematic Ribozyme Fitness Landscape Reveals a Frustrated Evolutionary Network for Self-Aminoacylating RNA.

Mixed Anhydride Intermediates in the Reaction of 5(4H)-Oxazolones with Phosphate Esters and Nucleotides

Monitoring clinical levels of heparin in human blood samples with an indicator-displacement assay

Non-uniform surface charge distributions in CE: theoretical and experimental approach based on Taylor dispersion.

On-line sample stacking of peptides in capillary electrophoresis for the study of prebiotic reactions between alpha,alpha-dialkylated amino acids and amino acid N-carboxyanhydrides.

Pathways for the formation and evolution of peptides in prebiotic environments.

Physicochemical Requirements Inferred for Chemical Self-Organization Hardly Support an Emergence of Life in the Deep Oceans of Icy Moons

Stability and its manifestation in the chemical and biological worlds

Structure of the third intracellular loop of the vasopressin V2 receptor and conformational changes upon binding to gC1qR.

The Activation of Free Dipeptides Promoted by Strong Activating Agents in Water Does not Yield Diketopiperazines.

The Chemical Likelihood of Ribonucleotide-α-Amino acid Copolymers as Players for Early Stages of Evolution

The Logic of Life

The Peptide Formation Mediated by Cyanate Revisited.N-Carboxyanhydrides as Accessible Intermediates in the Decomposition ofN-Carbamoylamino Acids

The Prebiotic C-Terminal Elongation of Peptides Can Be Initiated by N-Carbamoyl Amino Acids

The multifunctional protein GC1q-R interacts specifically with the i3 loop arginine cluster of the vasopressin V2 receptor.

The origin of life: what we know, what we can know and what we will never know.

Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics