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List of works by Tjalling Jager

A biology-based approach for mixture toxicity of multiple endpoints over the life cycle

scientific article

A biology-based approach for quantitative structure-activity relationships (QSARs) in ecotoxicity.

scientific article published on 19 October 2008

A model to analyze effects of complex mixtures on survival

scientific article published on 31 October 2008

A review of DEB theory in assessing toxic effects of mixtures.

scientific article published on 21 October 2009

Acute exposure of water soluble fractions of marine diesel on Arctic Calanus glacialis and boreal Calanus finmarchicus: Effects on survival and biomarker response

scientific article published on 19 February 2013

Acute toxicity of dispersed crude oil on the cold-water copepod Calanus finmarchicus: Elusive implications of lipid content.

scientific article published on January 2016

Adding Value to Ecological Risk Assessment with Population Modeling

article

Adjuvant therapy after resection of colorectal liver metastases: the predictive value of the MSKCC clinical risk score in the era of modern chemotherapy

scientific article

All Individuals Are Not Created Equal; Accounting for Interindividual Variation in Fitting Life-History Responses to Toxicants ⬇️

scientific article published on January 11, 2013

Application of physiologically based modelling and transcriptomics to probe the systems toxicology of aldicarb for Caenorhabditis elegans (Maupas 1900).

scientific article published on 21 January 2011

Automated, high-throughput measurement of size and growth curves of small organisms in well plates

scientific article published in Scientific Reports

Availability of polycyclic aromatic hydrocarbons to earthworms (Eisenia andrei, Oligochaeta) in field-polluted soils and soil-sediment mixtures

scientific article published on 01 April 2003

Bad habits die hard: the NOEC's persistence reflects poorly on ecotoxicology

scientific article published in February 2012

Bioaccumulation of organic chemicals in contaminated soils: evaluation of bioassays with earthworms

scientific article published in January 2005

Biphasic elimination and uptake kinetics of Zn and Cd in the earthworm Lumbricus rubellus exposed to contaminated floodplain soil

article

Body size-mediated starvation resistance in an insect predator

scientific article published on 13 January 2014

Cancer-related serological recognition of human colon cancer: identification of potential diagnostic and immunotherapeutic targets.

scientific article

Chronic exposure to chlorpyrifos reveals two modes of action in the springtail Folsomia candida.

scientific article published on 8 June 2006

Classification of current anticancer immunotherapies

scientific article

Clinical characteristics, treatment outcomes and potential novel therapeutic options for patients with neuroendocrine carcinoma of the prostate

Comment on "Robust Fit of Toxicokinetic-Toxicodynamic Models Using Prior Knowledge Contained in the Design of Survival Toxicity Tests".

scientific article

Comparison of two screening level risk assessment approaches for six disinfectants and pharmaceuticals

scientific article

Considerations for test design to accommodate energy-budget models in ecotoxicology: a case study for acetone in the pond snail Lymnaea stagnalis

scientific article

Corrigendum. Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis

scientific article published on 2 March 2015

DEBkiss or the quest for the simplest generic model of animal life history

scientific article published on 20 March 2013

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

scientific article published on 03 June 2019

Dynamic Links between Lipid Storage, Toxicokinetics and Mortality in a Marine Copepod Exposed to Dimethylnaphthalene

scientific article published on 9 June 2017

Dynamic modeling of sublethal mixture toxicity in the nematode Caenorhabditis elegans.

scientific article published on 6 June 2014

Efficacy of Cabazitaxel Treatment in Metastatic Castration Resistant Prostate Cancer in Second and Later Lines. An Experience from Two German Centers

scientific article published on 11 February 2017

Efficacy of targeted treatment beyond third-line therapy in metastatic kidney cancer: retrospective analysis from a large-volume cancer center

scientific article published on 30 December 2014

Elucidating the routes of exposure for organic chemicals in the earthworm, Eisenia andrei (Oligochaeta).

scientific article published in August 2003

European Union System for the Evaluation of Substances (EUSES). Principles and structure

scientific article published on April 1997

Evaluation of the diagnostic value of 64 simultaneously measured autoantibodies for early detection of gastric cancer

scientific article published on 3 May 2016

Extrapolating ecotoxicological effects from individuals to populations: a generic approach based on Dynamic Energy Budget theory and individual-based modeling.

scientific article published on 22 February 2013

Extrapolating toxic effects on individuals to the population level: the role of dynamic energy budgets

scientific article published on November 2010

From food-dependent statistics to metabolic parameters, a practical guide to the use of dynamic energy budget theory

scientific article

General unified threshold model of survival--a toxicokinetic-toxicodynamic framework for ecotoxicology

scientific article

Genomic features of renal cell carcinoma with venous tumor thrombus.

scientific article

Gill damage and delayed mortality of Northern shrimp (Pandalus borealis) after short time exposure to anti-parasitic veterinary medicine containing hydrogen peroxide

scientific article published on 20 May 2019

HLA-DP4 expression and immunity to NY-ESO-1: correlation and characterization of cytotoxic CD4+ CD25- CD8- T cell clones.

scientific article

Hormesis on life-history traits: is there such thing as a free lunch?

scientific article published on 25 November 2012

How to Evaluate the Quality of Toxicokinetic-Toxicodynamic Models in the Context of Environmental Risk Assessment

article by Tjalling Jager & Roman Ashauer published 24 March 2018 in Integrated Environmental Assessment and Management

Identification of cancer/testis genes by database mining and mRNA expression analysis

scientific article

Immune infiltrates are prognostic factors in localized gastrointestinal stromal tumors

scientific article

Impact of metal pools and soil properties on metal accumulation in Folsomia candida (Collembola)

scientific article published on 01 April 2001

Impact of resection and systemic therapy on the survival of patients with brain metastasis of metastatic renal cell carcinoma

scientific article published on 18 August 2016

Integrating population modeling into ecological risk assessment

scientific article published in January 2010

Interferon-alpha in combination with chemotherapy has potent antiangiogenic properties in an orthotopic mouse model for pancreatic adenocarcinoma

scientific article published on January 2008

Juvenile food limitation in standardized tests: a warning to ecotoxicologists.

scientific article

Kinetics of Zn and Cd accumulation in the isopod Porcellio scaber exposed to contaminated soil and/or food

Limitations of extrapolating toxic effects on reproduction to the population level

scientific article published in January 2014

Linking survival and biomarker responses over time ⬇️

scientific article published on June 21, 2013

Linking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans

scientific article

Local salvage therapy for late (≥2 years) metastatic and local relapse of renal cell cancer is a potentially curative treatment irrespective of the site of recurrence

scientific article published on 28 December 2015

Locally Advanced Pancreatic Cancer: Neoadjuvant Therapy With Folfirinox Results in Resectability in 60% of the Patients

scientific article published on 28 June 2016

Making Sense of Ecotoxicological Test Results: Towards Application of Process-based Models

article

Metal uptake from soils and soil-sediment mixtures by larvae of Tenebrio molitor (L.) (Coleoptera).

scientific article published in March 2003

Modeling ingestion as an exposure route for organic chemicals in earthworms (Oligochaeta).

scientific article

Modeling receptor kinetics in the analysis of survival data for organophosphorus pesticides

scientific article published in November 2005

Modeling responses of Daphnia magna to pesticide pulse exposure under varying food conditions: intrinsic versus apparent sensitivity

scientific article published on 6 October 2006

Modeling the environmental fate of perfluorooctanoate and its precursors from global fluorotelomer acrylate polymer use.

scientific article published in November 2008

Modelling survival: exposure pattern, species sensitivity and uncertainty

scientific article published on 6 July 2016

Modelling the dynamics of growth, development and lipid storage in the marine copepod Calanus finmarchicus.

scientific article published on 22 November 2016

Monitoring approaches to assess bioaccessibility and bioavailability of metals: matrix issues.

scientific article

NY-BR-1 is a differentiation antigen of the mammary gland

scientific article

Novel view on predicting acute toxicity: decomposing toxicity data in species vulnerability and chemical potency

scientific article

Opportunities for a probabilistic risk assessment of chemicals in the European Union

scientific article published on 01 April 2001

Pancreatic Cancer Surgery: The New R-status Counts

scientific article

Phase I/II trial evaluating carbon ion radiotherapy for the treatment of recurrent rectal cancer: the PANDORA-01 trial

scientific article

Physiological modes of action across species and toxicants: the key to predictive ecotoxicology

scientific article published in November 2017

Physiological modes of action of toxic chemicals in the nematode Acrobeloides nanus

scientific article published in December 2006

Predicting Mixture Effects over Time with Toxicokinetic–Toxicodynamic Models (GUTS): Assumptions, Experimental Testing, and Predictive Power

scientific article published in 2021

Predicting environmental risk: A road map for the future

scientific article published on January 2016

Predicting population dynamics from the properties of individuals: a cross-level test of dynamic energy budget theory

scientific article published on 8 March 2013

Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study

scientific article published on 24 January 2019

Prediction of Metal Bioavailability in Dutch Field Soils for the Oligochaete Enchytraeus crypticus

Prediction of daphnid survival after in situ exposure to complex mixtures

scientific article published in August 2009

Prediction of ecological no-effect concentrations for initial risk assessment: combining substance-specific data and database information

scientific article

Preferential nuclear and cytoplasmic NY-BR-1 protein expression in primary breast cancer and lymph node metastases

scientific article published on 01 May 2006

Priority assessment of toxic substances in life cycle assessment. Part I: Calculation of toxicity potentials for 181 substances with the nested multi-media fate, exposure and effects model USES–LCA

article

Priority assessment of toxic substances in life cycle assessment. Part II: assessing parameter uncertainty and human variability in the calculation of toxicity potentials

article

Prospective evaluation of 64 serum autoantibodies as biomarkers for early detection of colorectal cancer in a true screening setting

scientific article published on 19 February 2016

Quantification of Metal Bioavailability for Lettuce (Lactuca sativa L.) in Field Soils

scientific article published on 01 November 2000

Recombinant antigen expression on yeast surface (RAYS) for the detection of serological immune responses in cancer patients

article

Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients.

scholarly article

Reconsidering sufficient and optimal test design in acute toxicity testing

scientific article published on 7 November 2013

Relating Environmental Availability to Bioavailability: Soil-Type-Dependent Metal Accumulation in the Oligochaete Eisenia andrei

article by Willie Peijnenburg et al published November 1999 in Ecotoxicology and Environmental Safety

Resection of the primary tumour versus no resection prior to systemic therapy in patients with colon cancer and synchronous unresectable metastases (UICC stage IV): SYNCHRONOUS - a randomised controlled multicentre trial (ISRCTN30964555) ⬇️

scientific article published on April 5, 2012

Robust likelihood-based approach for automated optimisation and uncertainty analysis of toxicokinetic-toxicodynamic models

scientific article published on 29 August 2020

Scaling relationships based on partition coefficients and body sizes have similarities and interactions.

scientific article

Seromic profiling of ovarian and pancreatic cancer

scientific article

Short-term ecological risks of depositing contaminated sediment on arable soil

scientific article published in January 2005

Simplified Dynamic Energy Budget model for analysing ecotoxicity data

article

Simultaneous modeling of multiple end points in life-cycle toxicity tests

scientific article published on 01 May 2004

Solid-phase microextraction to predict bioavailability and accumulation of organic micropollutants in terrestrial organisms after exposure to a field-contaminated soil.

scientific article published in September 2004

Some Good Reasons to Ban ECx and Related Concepts in Ecotoxicology ⬇️

scientific article published on September 15, 2011

Sorption kinetics and microbial biodegradation activity of hydrophobic chemicals in sewage sludge: model and measurements based on free concentrations

scientific article published in January 2003

Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity

scientific article published on 13 June 2016

Stage-dependent and sex-dependent sensitivity to water-soluble fractions of fresh and weathered oil in the marine copepod Calanus finmarchicus.

scientific article published on 9 February 2016

Survival and prognostic factors of patients with renal cell cancer with bone metastasis in the era of targeted therapy: A single-institution analysis

scientific article published on 16 June 2016

Survival outcomes of patients with germ cell tumors treated with high-dose chemotherapy for refractory or relapsing disease.

scientific article

Targeted therapy of renal cell carcinoma: synergistic activity of cG250-TNF and IFNg.

scientific article published in July 2009

Temperature-dependent effects of cadmium on Daphnia magna: accumulation versus sensitivity

scientific article published in May 2003

Temporal dynamics of effect concentrations

scientific article published on 01 April 2006

The relationship between elimination rates and partition coefficients

scientific article published in November 2004

Time is of the essence

scientific article published in June 2010

Time-related survival effects of two gluconasturtiin hydrolysis products on the terrestrial isopod Porcellio scaber

scientific article

Topography of cancer-associated immune cells in human solid tumors

Toxicokinetic-toxicodynamic modeling of quantal and graded sublethal endpoints: a brief discussion of concepts

scientific article published on 24 August 2011

Toxicokinetics of Crude Oil Components in Arctic Copepods

scientific article published on 09 August 2018

Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis

scientific article

Understanding toxicity as processes in time

scientific article published on 6 December 2009

Uniform System for the Evaluation of Substances. IV. Distribution and intake

scientific article published on 01 July 1994

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