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List of works by Michele Ciccarelli

"Freeze, Don't Move": How to Arrest a Suspect in Heart Failure - A Review on Available GRK2 Inhibitors

scientific article

A Micro-computed Tomography Evaluation of the Shaping Ability of Two Nickel-titanium Instruments, HyFlex EDM and ProTaper Next

scientific article published on 15 February 2017

A Novel Promising Frontier for Human Health: The Beneficial Effects of Nutraceuticals in Cardiovascular Diseases

scientific article published on 18 November 2020

A Novel Small Peptide Inhibitor of NFB, RH10, Blocks Oxidative Stress-Dependent Phenotypes in Cancer

scientific article published on 04 November 2018

A Polymorphism within the Promoter of the Dopamine Receptor D1 (DRD1 -48A/G) Associates with Impaired Kidney Function in White Hypertensive Patients ⬇️

scientific article published on January 18, 2012

AKT participates in endothelial dysfunction in hypertension

scientific article

Adrenergic receptors and metabolism: role in development of cardiovascular disease

scientific article published on 03 October 2013

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

scientific article published in 2022

Antidiabetic and Cardioprotective Effects of Pharmacological Inhibition of GRK2 in db/db Mice ⬇️

scientific article published on 25 March 2019

Association Study Between Coronary Artery Disease and rs1333049 Polymorphism at 9p21.3 Locus in Italian Population.

scientific article published on 21 June 2017

Beta(2)-adrenergic receptor gene delivery to the endothelium corrects impaired adrenergic vasorelaxation in hypertension

scientific article

CaMKII Activity in the Inflammatory Response of Cardiac Diseases

scientific article published on 06 September 2019

CaMKII protects MKP-1 from proteasome degradation in endothelial cells

scientific article published on 05 July 2014

Cardiac eccentric remodeling in patients with rheumatoid arthritis.

scientific article

Cardiotoxic Effects of Short-Term Doxorubicin Administration: Involvement of Connexin 43 in Calcium Impairment.

scientific article

Cellular subtype expression and activation of CaMKII regulate the fate of atherosclerotic plaque.

scientific article published on 5 November 2016

Cross-Talk between Neurohormonal Pathways and the Immune System in Heart Failure: A Review of the Literature ⬇️

scientific article published on 05 April 2019

Dermcidin: a skeletal muscle myokine modulating cardiomyocyte survival and infarct size after coronary artery ligation.

scientific article published on 22 June 2015

Diazoxide Improves Mitochondrial Connexin 43 Expression in a Mouse Model of Doxorubicin-Induced Cardiotoxicity.

scientific article published on 7 March 2018

Dual role of GRK5 in cancer development and progression

scientific article published on 16 May 2016

Endothelial G protein-coupled receptor kinase 2 regulates vascular homeostasis through the control of free radical oxygen species

scientific article published on 15 August 2013

Endothelial alpha1-adrenoceptors regulate neo-angiogenesis

scientific article

Erratum to: Association Study between Coronary Artery Disease and rs1333049 Polymorphism at 9p21.3 Locus in Italian Population

scientific article published on 01 December 2017

Exercise promotes angiogenesis and improves beta-adrenergic receptor signalling in the post-ischaemic failing rat heart.

scientific article

Exploiting GRK2 Inhibition as a Therapeutic Option in Experimental Cancer Treatment: Role of p53-Induced Mitochondrial Apoptosis

scientific article published on 26 November 2020

Functional Role of Mitochondria in Arrhythmogenesis.

scientific article

G Protein-Coupled Receptor Kinase 2 in Patients With Acute Myocardial Infarction

scientific article published on 04 February 2011

G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia.

scientific article

G protein-coupled receptor kinase 2: a link between myocardial contractile function and cardiac metabolism

scientific article

GRK2 at the control shaft of cellular metabolism.

scientific article

GRK2 moderates the acute mitochondrial damage to ionizing radiation exposure by promoting mitochondrial fission/fusion

scientific article published on 14 February 2018

Good at Heart: Preserving Cardiac Metabolism during aging.

scientific article published on 22 July 2015

Growth inhibition of human hepatocellular carcinoma cells by overexpression of G-protein-coupled receptor kinase 2.

scientific article published on June 2012

Impaired neoangiogenesis in β₂-adrenoceptor gene-deficient mice: restoration by intravascular human β₂-adrenoceptor gene transfer and role of NFκB and CREB transcription factors

scientific article published on February 2011

Inflammatory mediators in a short-time mouse model of doxorubicin-induced cardiotoxicity.

scientific article published on 9 January 2016

Integrating GRK2 and NFkappaB in the Pathophysiology of Cardiac Hypertrophy

scientific article published on 30 July 2015

Ischemic neoangiogenesis enhanced by beta2-adrenergic receptor overexpression: a novel role for the endothelial adrenergic system

scientific article published on 20 October 2005

It is easy to see, but it is better to foresee: a case report on the favourable alliance between CardioMEMS and levosimendan

scientific article published on 30 June 2020

Larger Blood Pressure Reduction by Fixed-Dose Compared to Free Dose Combination Therapy of ACE Inhibitor and Calcium Antagonist in Hypertensive Patients

scientific article published on January 2017

Mechanistic Role of Kinases in the Regulation of Mitochondrial Fitness.

scientific article published in January 2017

Metabolic Syndrome and Aging: Calcium Signaling as Common Regulator

scientific article published on 22 July 2015

Mitochondrial G protein coupled receptor kinase 2 regulates proinflammatory responses in macrophages

scientific article published on 10 September 2013

Myocardial Ablation of G Protein–Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway ⬇️

scientific article published on June 21, 2013

New small molecules, ISA27 and SM13, inhibit tumour growth inducing mitochondrial effects of p53

scientific article

Parathyroid Hormone Causes Endothelial Dysfunction by Inducing Mitochondrial ROS and Specific Oxidative Signal Transduction Modifications

scientific article published on 19 December 2018

Pharmacological inhibition of GRK2 improves cardiac metabolism and function in experimental heart failure

scientific article published on 30 April 2020

Physical activity ameliorates cardiovascular health in elderly subjects: the functional role of the β adrenergic system.

scientific article published on 12 August 2013

Precision and Personalized Medicine: How Genomic Approach Improves the Management of Cardiovascular and Neurodegenerative Disease

scientific article published on 06 July 2020

Prior exercise improves age-dependent vascular endothelial growth factor downregulation and angiogenesis responses to hind-limb ischemia in old rats

scientific article published on 01 May 2007

Rays Sting: The Acute Cellular Effects of Ionizing Radiation Exposure

scientific article published on 16 May 2016

Reward Preferences of Pathological Gamblers Under Conditions of Uncertainty: An Experimental Study

scientific article

Sirt1 Activity in PBMCs as a Biomarker of Different Heart Failure Phenotypes

scientific article published on 23 November 2020

Targeting the CaMKII/ERK Interaction in the Heart Prevents Cardiac Hypertrophy

scientific article published on 25 June 2015

The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC.

scientific article published on 15 January 2018

The novel butyrate derivative phenylalanine-butyramide protects from doxorubicin-induced cardiotoxicity

scientific article published on 06 March 2019

The possible role of chromosome X variability in hypertensive familiarity

scientific article published on 25 February 2016

Trafficking GRK2: Cellular and Metabolic consequences of GRK2 subcellular localization

scientific article

Vitamin D, parathyroid hormone and cardiovascular risk: the good, the bad and the ugly

scientific article

We are What We Eat: Impact of Food from Short Supply Chain on Metabolic Syndrome

scientific article published on 23 November 2019

β2-Adrenergic receptor stimulation improves endothelial progenitor cell-mediated ischemic neoangiogenesis.

scientific article published on 15 February 2013

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