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List of works by Richard A. Larson

A Morphologic and Cytochemical Study of Acute Myelomonocytic Leukemia with Abnormal Marrow Eosinophils Associated with Inv(16)(p13q22) ⬇️

scientific article published on 01 June 1984

A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.

scientific article published on 17 June 2013

A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403

scientific article published on 18 January 2019

A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia

scientific article published on 01 February 2020

A phase 2 study incorporating sorafenib into the chemotherapy for older adults with -mutated acute myeloid leukemia: CALGB 11001

article published in 2017

A phase 3 study of gemtuzumab ozogamicin during induction and postconsolidation therapy in younger patients with acute myeloid leukemia

scientific article published on 16 April 2013

A phase I and pharmacodynamic study of the histone deacetylase inhibitor belinostat plus azacitidine in advanced myeloid neoplasia

scientific article

A phase I and pharmacokinetic study of XK469R (NSC 698215), a quinoxaline phenoxypropionic acid derivative, in patients with refractory acute leukemia

scientific article published on 19 April 2008

A phase I study of selinexor in combination with high-dose cytarabine and mitoxantrone for remission induction in patients with acute myeloid leukemia

scientific article published on 5 January 2018

A phase I trial of gemcitabine plus cladribine in patients with advanced hematologic malignant diseases

scientific article

A phase II study of cladribine treatment for fludarabine refractory B cell chronic lymphocytic leukemia: results from CALGB Study 9211.

scientific article

A phase II study of continuous infusion homoharringtonine and cytarabine in newly diagnosed patients with chronic myeloid leukemia: CALGB study 19804.

scientific article published in August 2008

A phase II study of the oral VEGF receptor tyrosine kinase inhibitor vatalanib (PTK787/ZK222584) in myelodysplastic syndrome: Cancer and Leukemia Group B study 10105 (Alliance).

scientific article published on 23 May 2013

A pilot study of prophylactic aerosolized amphotericin B in patients at risk for prolonged neutropenia

scientific article published in October 1992

A randomized controlled trial of filgrastim during remission induction and consolidation chemotherapy for adults with acute lymphoblastic leukemia: CALGB study 9111 ⬇️

scientific article published on September 1, 1998

A randomized trial of dasatinib 100 mg versus imatinib 400 mg in newly diagnosed chronic-phase chronic myeloid leukemia

scientific article

A randomized, double-blind, placebo-controlled phase 2 study evaluating the efficacy and safety of romiplostim treatment of patients with low or intermediate-1 risk myelodysplastic syndrome receiving lenalidomide

scientific article

A recurring chromosome rearrangement, dic(16;22), in acute nonlymphocytic leukemia

scientific article published on October 1988

A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare ‘poor prognosis’ myeloid malignancies

scientific article published on 20 April 2006

ACUTE MYELOID LEUKAEMIA FOLLOWING INTERFERON-ALFA TREATMENT OF HAIRY CELL LEUKAEMIA

scientific article published on 01 March 1993

ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category

scientific article

Abnormal Cytogenetics at Date of Morphologic Complete Remission Predicts Short Overall and Disease-Free Survival, and Higher Relapse Rate in Adult Acute Myeloid Leukemia: Results From Cancer and Leukemia Group B Study 8461

article

Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study.

scientific article

Acquired FANCA dysfunction and cytogenetic instability in adult acute myelogenous leukemia.

scientific article published on 13 March 2003

Acral Lividosis—A Sign of Myeloproliferative Diseases

scientific article published on 01 July 1987

Acute leukemia in adults: recent developments in diagnosis and treatment.

scientific article published on November 1994

Acute leukemia occurring after radiotherapy and chemotherapy with a nitrosourea, PCNU

scientific article published on 01 June 1988

Acute lymphoblastic leukaemia: diagnosis and classification.

scientific article

Acute myeloid leukemia: the challenge of unfavorable cytogenetics

scientific article published on August 1, 2012

Acute myelomonocytic leukemia with abnormal eosinophils and inv(16) or t(16;16) has a favorable prognosis

scientific article published on 01 December 1986

Acute myelomonocytic leukemia with abnormal eosinophils presenting as an ovarian mass: a report of two cases and a review of the literature.

scientific article published on February 1995

Acute nonlymphocytic leukemia following etoposide and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung

scientific article published on 01 November 1987

Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011.

scientific article

Additional cytogenetic abnormalities in adults with Philadelphia chromosome-positive acute lymphoblastic leukaemia: a study of the Cancer and Leukaemia Group B.

scientific article

Adult de novo acute myeloid leukemia with t(6;11)(q27;q23): results from Cancer and Leukemia Group B Study 8461 and review of the literature

scientific article published in September 2004

Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): a Cancer and Leukemia Group B Study

scientific article

Age-related prognostic impact of different types of DNMT3A mutations in adults with primary cytogenetically normal acute myeloid leukemia

scientific article

Allogeneic Hematopoietic Cell Transplantation Is Not Recommended for all Adults with Standard-Risk Acute Lymphoblastic Leukemia in First Complete Remission

scientific article published on 01 January 2009

Allogeneic Hematopoietic Cell Transplantation for Therapy-Related Myeloid Leukemia following Orthotopic Cardiac Transplantation

scientific article published on 30 March 2013

Allogeneic hematopoietic cell transplantation compared to chemotherapy consolidation in older acute myeloid leukemia (AML) patients 60-75 years in first complete remission (CR1): an alliance (A151509), SWOG, ECOG-ACRIN, and CIBMTR study

scientific article published on 09 May 2019

Allogeneic hematopoietic cell transplantation for adults with ALL.

scientific article published on August 2008

Allogeneic stem cell transplantation with alemtuzumab-based conditioning for patients with advanced chronic myelogenous leukemia.

scientific article published on January 2009

Amelanocytic Anhidrotic Alopecia Areata-like Phenotype After Allogeneic Hematopoietic Cell Transplant

scientific article published on 01 August 2012

An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

scientific article

An integrated genomic approach to the assessment and treatment of acute myeloid leukemia.

scientific article published on April 2011

Analysis of age, estimated creatinine clearance and pretreatment hematologic parameters as predictors of fludarabine toxicity in patients treated for chronic lymphocytic leukemia: a CALGB (9011) coordinated intergroup study

scientific article

Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin).

scientific article

Arsenic trioxide during consolidation for patients with previously untreated low/intermediate risk acute promyelocytic leukaemia may eliminate the need for maintenance therapy

scientific article

Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710.

scientific article

Arsenic trioxide in front-line therapy of acute promyelocytic leukemia (C9710): prognostic significance of FLT3 mutations and complex karyotype

scientific article

Assessment of Outcomes After Stopping Tyrosine Kinase Inhibitors Among Patients With Chronic Myeloid Leukemia: A Nonrandomized Clinical Trial

scientific article published on 12 November 2020

Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders

scientific article

Assignment of the GM-CSF, CSF-1, and FMS genes to human chromosome 5 provides evidence for linkage of a family of genes regulating hematopoiesis and for their involvement in the deletion (5q) in myeloid disorders

scientific article published on 01 January 1986

Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia

scientific article published on 01 November 1987

Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. A unique cytogenetic-clinicopathological association

scientific article published on 01 September 1983

Associations between morphology, karyotype, and clinical features in myeloid leukemias.

scientific article

Author Correction: RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia.

scientific article

Auto-SCT for AML in second remission: CALGB study 9620.

scientific article published on 16 March 2009

Autologous transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia achieves outcomes similar to allogeneic transplantation: results of CALGB Study 10001 (Alliance).

scientific article

BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study

scientific article published on 15 May 2003

BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia

scientific article published on 14 August 2014

Balanced chromosome abnormalities inv(16) and t(15;17) in therapy-related myelodysplastic syndromes and acute leukemia: report from an international workshop

scientific article published in April 2002

Balanced translocations involving chromosome bands 11q23 and 21q22 in therapy-related leukemia ⬇️

scientific article published on 01 April 1992

Biological characteristics of newly diagnosed poor prognosis acute myelogenous leukemia

scientific article published on 01 April 1993

Blinatumomab treatment of older adults with relapsed/refractory B-precursor acute lymphoblastic leukemia: Results from 2 phase 2 studies

scientific article published on 3 May 2016

Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia

scientific article

Bortezomib added to daunorubicin and cytarabine during induction therapy and to intermediate-dose cytarabine for consolidation in patients with previously untreated acute myeloid leukemia age 60 to 75 years: CALGB (Alliance) study 10502.

scientific article published on 5 November 2012

CBFA2(AML1) translocations with novel partner chromosomes in myeloid leukemias: association with prior therapy ⬇️

scientific article published on October 15, 1998

CML: live long and prosper ⬇️

scientific article published on October 27, 2011

Cancer and Leukemia Group B (CALGB) studies in adult acute lymhocytic leukemia

scientific article published on January 1, 1992

Cardiac tamponade in a patient with chronic lymphocytic leukemia

scientific article published on 01 April 2007

Certain HLA antigens are associated with specific morphologic and cytogenetic subsets of acute myeloid leukemia.

scientific article published in March 1995

Changing the cost of care for chronic myeloid leukemia: the availability of generic imatinib in the USA and the EU

scientific article

Characterization of cancer comorbidity prior to allogeneic hematopoietic cell transplantation

scientific article published on 02 August 2018

Chemoimmunotherapy with fludarabine and rituximab produces extended overall survival and progression-free survival in chronic lymphocytic leukemia: long-term follow-up of CALGB study 9712

scientific article

Cholesterol and mevalonic acid are independent requirements for the in vitro proliferation of human bone marrow granulocyte progenitor cells: studies using ML-236B

scientific article published on 01 April 1983

Chromosomal loss and deletion are the most common mechanisms for loss of heterozygosity from chromosomes 5 and 7 in malignant myeloid disorders ⬇️

scientific article published on March 15, 1992

Chromosomal sensitivity of lymphocytes from individuals with therapy-related acute nonlymphocytic leukemia

scientific article published on 01 April 1989

Chromosome changes in hematologic malignancies.

scientific article published on July 1981

Chronic lymphocytic leukemia masquerading as uveitis

scientific article published in November 2007

Chronic myeloid leukemia: an update of concepts and management recommendations of European LeukemiaNet

scientific article

Circulating immune complexes correlate with remission duration in acute myeloid leukemia

scientific article published on 01 February 1991

Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7

scientific article

Clinical and cytogenetic responses to granulocyte-macrophage colony-stimulating factor in therapy-related myelodysplasia ⬇️

scientific article published on November 15, 1992

Clinical and prognostic significance of chromosomal abnormalities in childhood acute myeloid leukemia de novo

scientific article published on 01 January 1995

Clinical efficacy of high-dose dexamethasone with maintenance dexamethasone/alpha interferon in patients with primary systemic amyloidosis: results of United States Intergroup Trial Southwest Oncology Group (SWOG) S9628.

scientific article

Clinical impact of ABL1 kinase domain mutations and IKZF1 deletion in adults under age 60 with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL): molecular analysis of CALGB (Alliance) 10001 and 9665.

scientific article

Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

Clinical outcomes of IDH2-mutated advanced-phase Ph-negative myeloproliferative neoplasms treated with enasidenib

scientific article published on 01 May 2020

Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: a Cancer and Leukemia Group B Study (8762) ⬇️

scientific article published on December 15, 1992

Clinical, morphologic, and cytogenetic characteristics of 26 patients with acute erythroblastic leukemia ⬇️

scientific article published on 01 December 1992

Clinical, morphologic, and cytogenetic characteristics of patients with lymphoid malignancies characterized by both t(14;18)(q32;q21) and t(8;14)(q24;q32) or t(8;22)(q24;q11)

scientific article published on 01 July 1990

Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series.

scientific article

Clinicopathologic manifestations and breakpoints of the t(3;5) in patients with acute nonlymphocytic leukemia

scientific article published on January 1989

Combination of dasatinib with chemotherapy in previously untreated core binding factor acute myeloid leukemia: CALGB 10801

scientific article published on 01 February 2020

Comparison of cytogenetic and molecular genetic detection of t(8;21) and inv(16) in a prospective series of adults with de novo acute myeloid leukemia: a Cancer and Leukemia Group B Study

scientific article published on 01 May 2001

Comparison of reduced-intensity hematopoietic cell transplantation with chemotherapy in patients age 60-70 years with acute myelogenous leukemia in first remission

scientific article

Complex rearrangement of the T cell receptor in large granular lymphocytosis associated with myeloid suppression

scientific article published on 01 December 1990

Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.

scientific article published on 5 February 2007

Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia.

scientific article published on 11 April 2016

Concomitant amphotericin B therapy, granulocyte transfusions, and GM-CSF administration for disseminated infection with Fusarium in a granulocytopenic patient

scientific article

Concurrent use of proton pump inhibitors or H2 blockers did not adversely affect nilotinib efficacy in patients with chronic myeloid leukemia

scientific article published on 24 May 2012

Consolidation therapy with subcutaneous alemtuzumab after fludarabine and rituximab induction therapy for previously untreated chronic lymphocytic leukemia: final analysis of CALGB 10101

scientific article

Core binding factor acute myeloid leukemia. Cancer and Leukemia Group B (CALGB) Study 8461.

scientific article

Cost-effectiveness of Tyrosine Kinase Inhibitor Treatment Strategies for Chronic Myeloid Leukemia in Chronic Phase After Generic Entry of Imatinib in the United States

scientific article published on 04 March 2016

Current practices in the management of chronic myeloid leukemia.

scientific article published on 25 October 2012

Cytogenetic and genetic pathways in therapy-related acute myeloid leukemia.

scientific article

Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases.

scientific article

Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases

scientific article

Cytogenetic clonality in myelodysplastic syndromes studied with fluorescence in situ hybridization: lineage, response to growth factor therapy, and clone expansion

scientific article published on 01 March 1993

Cytogenetic prioritization with inclusion of molecular markers predicts outcome in previously untreated patients with chronic lymphocytic leukemia treated with fludarabine or fludarabine plus cyclophosphamide: a long-term follow-up study of the US i

scientific article

Cytogenetics, Not Just Previous Therapy, Determines the Course of Therapy-Related Myeloid Neoplasms ⬇️

scientific article published on May 14, 2012

Dasatinib 140 mg once daily versus 70 mg twice daily in patients with Ph-positive acute lymphoblastic leukemia who failed imatinib: Results from a phase 3 study

scientific article published on March 2010

Dasatinib in the treatment of chronic myeloid leukemia in accelerated phase after imatinib failure: the START a trial

scientific article

Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib.

scientific article

Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: interim results of a phase 2 study

scientific article

Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in accelerated phase

article

Dasatinib-Related Pulmonary Toxicity Mimicking an Atypical Infection

scientific article published on 23 June 2014

Deletions of Interferon Genes in Acute Lymphoblastic Leukemia

article

Design and rationale for the life after stopping tyrosine kinase inhibitors (LAST) study, a prospective, single-group longitudinal study in patients with chronic myeloid leukemia.

scientific article published on 2 April 2018

Detection of MLL gene rearrangements in adult acute lymphoblastic leukemia. A Cancer and Leukemia Group B study

scientific article published on 01 November 1994

Detection of trisomy 12 in chronic lymphocytic leukemia by fluorescence in situ hybridization to interphase cells: a simple and sensitive method ⬇️

scientific article published on 01 April 1992

Determinants of fatal bleeding during induction therapy for acute promyelocytic leukemia in the ATRA era.

scientific article published on 12 January 2017

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

scientific article

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

scientific article (publication date: 30 October 2009)

Differences in prognostic factors and outcomes in African Americans and whites with acute myeloid leukemia

scientific article published on 19 February 2004

Discontinuing imatinib in chronic myeloid leukemia: don't try this at home.

scientific article

Disseminated cutaneous and peritoneal hyalohyphomycosis caused by Fusarium species: three cases and review of the literature.

scientific article published on February 1988

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.

scholarly article

Does microgranular variant morphology of acute promyelocytic leukemia independently predict a less favorable outcome compared with classical M3 APL? A joint study of the North American Intergroup and the PETHEMA Group

scientific article

Dose escalation prophylactic donor lymphocyte infusion after T-cell depleted matched related donor allogeneic hematopoietic cell transplantation is feasible and results in higher donor chimerism, faster immune re-constitution, and prolonged progress

scientific article published on 28 January 2020

Dose escalation studies of cytarabine, daunorubicin, and etoposide with and without multidrug resistance modulation with PSC-833 in untreated adults with acute myeloid leukemia younger than 60 years: final induction results of Cancer and Leukemia Gr

scientific article published in November 2004

Dose intensification of daunorubicin and cytarabine during treatment of adult acute lymphoblastic leukemia: results of Cancer and Leukemia Group B Study 19802.

scientific article

Dose-escalation trial of cladribine using five daily intravenous infusions in patients with advanced hematologic malignancies

scientific article published on January 1996

Dose-ranging pharmacodynamic study of tipifarnib (R115777) in patients with relapsed and refractory hematologic malignancies

scientific article published in December 2004

Early molecular response predicts outcomes in patients with chronic myeloid leukemia in chronic phase treated with frontline nilotinib or imatinib

scientific article

Effect of age on the pharmacokinetics of busulfan in patients undergoing hematopoietic cell transplantation; an alliance study (CALGB 10503, 19808, and 100103).

scientific article

Effective asparagine depletion with pegylated asparaginase results in improved outcomes in adult acute lymphoblastic leukemia: Cancer and Leukemia Group B Study 9511

scientific article published on 30 January 2007

Effects of rhGM-CSF on Myeloid Clonogenic Cells in Acute Myelogenous Leukemia Patients

scientific article published on 01 June 1993

Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse

scientific article (publication date: July 2001)

Efficacy of imatinib dose escalation in patients with chronic myeloid leukemia in chronic phase

scientific article published on February 2009

Encephalopathy is the dose-limiting toxicity of intravenous hepsulfam: results of a phase I trial in patients with advanced hematological malignancies

scientific article

Encephalopathy is the dose-limiting toxicity of intravenous hepsulfam: results of a phase I trial in patients with advanced hematological malignancies

article

End points to establish the efficacy of new agents in the treatment of acute leukemia

scientific article published on 9 November 2006

Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles.

scientific article published on 8 June 2016

Erratum: Efficacy of imatinib dose escalation in patients with chronic myeloid leukemia in chronic phase

scholarly article published in Cancer

Erratum: Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up

scholarly article published in Leukemia

Erratum: Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia

scholarly article published in Leukemia

Escalation of daunorubicin and addition of etoposide in the ADE regimen in acute myeloid leukemia patients aged 60 years and older: Cancer and Leukemia Group B Study 9720.

scientific article published on 15 February 2011

Establishment and characterization of a megakaryoblast cell line with amplification of MLL ⬇️

scientific article published on July 1, 1998

Establishment of a leukemia cell line with i(12p) from a patient with a mediastinal germ cell tumor and acute lymphoblastic leukemia

scientific article published on September 1994

European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia

scientific article published on 03 March 2020

European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013.

scientific article published on 26 June 2013

Evaluation of event-free survival as a robust end point in untreated acute myeloid leukemia (Alliance A151614)

scientific article published on 01 June 2019

Evidence for a 15; 17 translocation in every patient with acute promyelocytic leukemia

article

Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders

scientific article

Evolving concepts in the management of chronic myeloid leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet

scientific article

Exposure-adjusted adverse events comparing blinatumomab with chemotherapy in advanced acute lymphoblastic leukemia

scientific article published on 01 July 2018

Expression and polymorphism (rs4880) of mitochondrial superoxide dismutase (SOD2) and asparaginase induced hepatotoxicity in adult patients with acute lymphoblastic leukemia.

scientific article published on 29 March 2016

Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.

scientific article

FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications

scientific article

FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

FLT3 mutation status is a predictor of early death in pediatric acute promyelocytic leukemia: a report from the Children's Oncology Group

scientific article

FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase.

scientific article published on 13 December 2016

Familial myeloid leukemia associated with loss of the long arm of chromosome 5

scientific article published on 01 April 1996

Fate of patients with newly diagnosed acute myeloid leukemia who fail primary induction therapy

scientific article

Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated gene- and microRNA-expression signatures: a Cancer and Leukemia Group B study

scientific article

Feasibility of administering oblimersen (G3139; Genasense) with imatinib mesylate in patients with imatinib resistant chronic myeloid leukemia--Cancer and leukemia group B study 10107.

scientific article

Fifty years of clinical research by the leukemia committee of the cancer and leukemia group B.

scientific article

Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence

scientific article

Final results of EFC6663: a multicenter, international, phase 2 study of alvocidib for patients with fludarabine-refractory chronic lymphocytic leukemia

scientific article

Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

scientific article (publication date: 7 December 2006)

Flavopiridol administered as a 24-hour continuous infusion in chronic lymphocytic leukemia lacks clinical activity

scientific article

Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia

scientific article (publication date: 14 December 2000)

Fludarabine followed by alemtuzumab consolidation for previously untreated chronic lymphocytic leukemia: final report of Cancer and Leukemia Group B study 19901.

scientific article published in October 2009

Fludarabine, melphalan, and alemtuzumab conditioning in adults with standard-risk advanced acute myeloid leukemia and myelodysplastic syndrome

scientific article published on 11 July 2005

Four different regimens of farnesyltransferase inhibitor tipifarnib in older, untreated acute myeloid leukemia patients: North American Intergroup Phase II study SWOG S0432.

scientific article

Frequency and Risk Factors Associated with Cord Graft Failure after Transplant with Single-Unit Umbilical Cord Cells Supplemented by Haploidentical Cells with Reduced-Intensity Conditioning

scientific article published on 18 February 2016

Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B.

scientific article

G3139, a BCL-2 antisense oligo-nucleotide, in AML

scientific article published in January 2004

Gemtuzumab ozogamicin: time to resurrect?

scientific article

Gene expression profiles in acute myeloid leukemia with common translocations using SAGE.

scientific article published on 17 January 2006

Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?

scientific article published on April 2011

Genetic pathways leading to therapy-related myeloid neoplasms ⬇️

scientific article

Genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibility

scientific article published on 18 March 2009

Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.

scientific article

Genomic aberrations in myeloid sarcoma without blood or bone marrow involvement: characterization of formalin-fixed paraffin-embedded samples by chromosomal microarrays

scientific article

Geriatric assessment among older adults receiving intensive therapy for acute myeloid leukemia: Report of CALGB 361006 (Alliance)

scientific article published on 24 October 2019

Geriatric assessment to predict survival in older allogeneic hematopoietic cell transplantation recipients.

scientific article

Gilteritinib or Chemotherapy for Relapsed or Refractory FLT3-Mutated AML

scientific article published on 01 October 2019

High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CAL

scientific article published on 31 March 2008

High Expression Levels of theETS-Related Gene,ERG, Predict Adverse Outcome and Improve Molecular Risk-Based Classification of Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

article

High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML).

scientific article published in March 2012

High dose cytarabine plus gemtuzumab ozogamicin for patients with relapsed or refractory acute myeloid leukemia: Cancer and Leukemia Group B study 19902.

scientific article

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

scientific article published on 20 May 2009

High frequency of immunophenotype changes in acute myeloid leukemia at relapse: implications for residual disease detection (Cancer and Leukemia Group B Study 8361)

scientific article published on 01 June 2001

High rates of durable response are achieved with imatinib after treatment with interferon alpha plus cytarabine: results from the International Randomized Study of Interferon and STI571 (IRIS) trial

scientific article published on 31 July 2009

High-dose Ara-C plus VM-26 in adult acute lymphoblastic leukemia

scientific article published on 01 October 1985

High-energy total body irradiation as preparation for bone marrow transplantation in leukemia patients: Treatment technique and related complications

scientific article published on 01 January 1998

Histone Deacetylase Inhibitor Romidepsin Has Differential Activity in Core Binding Factor Acute Myeloid Leukemia

scientific article (publication date: November 2008)

Hypercalcemia and Lytic Bone Lesions in a Patient with B-Cell Non-Hodgkin's Lymphoma ⬇️

scientific article published on January 26, 1984

Hypersensitivity reactions to L-asparaginase do not impact on the remission duration of adults with acute lymphoblastic leukemia ⬇️

scientific article published on 01 May 1998

IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL

Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study

scientific article published on 4 February 2013

Identifying Inherited and Acquired Genetic Factors Involved in Poor Stem Cell Mobilization and Donor-Derived Malignancy

scientific article published on 4 August 2016

Imatinib 800 mg daily induces deeper molecular responses than imatinib 400 mg daily: results of SWOG S0325, an intergroup randomized PHASE II trial in newly diagnosed chronic phase chronic myeloid leukaemia

scientific article

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

scientific article

Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study.

scientific article published in May 2002

Imatinib is still recommended for frontline therapy for CML

Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study

scientific article published on 6 February 2008

Immune reconstitution after combined haploidentical and umbilical cord blood transplant

scientific article published in March 2013

Impact of NPM1/FLT3-ITD genotypes defined by the 2017 European LeukemiaNet in patients with acute myeloid leukemia

scientific article published on 01 January 2020

Impact of age on outcomes after initial therapy with chemotherapy and different chemoimmunotherapy regimens in patients with chronic lymphocytic leukemia: results of sequential cancer and leukemia group B studies

scientific article published on 10 December 2012

Impact of azacytidine on the quality of life of patients with myelodysplastic syndrome treated in a randomized phase III trial: a Cancer and Leukemia Group B study

scientific article

Impact of disease burden at time of allogeneic stem cell transplantation in adults with acute myeloid leukemia and myelodysplastic syndromes

scientific article published on 01 May 2005

Impact of therapy With chlorambucil, fludarabine, or fludarabine plus chlorambucil on infections in patients with chronic lymphocytic leukemia: Intergroup Study Cancer and Leukemia Group B 9011.

scientific article

Improved efficacy using rituximab and brief duration, high intensity chemotherapy with filgrastim support for Burkitt or aggressive lymphomas: cancer and Leukemia Group B study 10 002.

scientific article published on 15 January 2014

In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs

scientific article published on 23 July 2015

Incidence and predictors of respiratory viral infections by multiplex PCR in allogeneic hematopoietic cell transplant recipients 50 years and older including geriatric assessment.

scientific article published on 24 December 2015

Incidence of therapy-related myeloid neoplasia after initial therapy for chronic lymphocytic leukemia with fludarabine-cyclophosphamide versus fludarabine: long-term follow-up of US Intergroup Study E2997.

scientific article

Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study

scientific article published on 2 May 2006

Individual patient data meta-analysis of randomized trials evaluating IL-2 monotherapy as remission maintenance therapy in acute myeloid leukemia

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Influence of related donor age on outcomes after peripheral blood stem cell transplantation

scientific article published on 2 May 2012

Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia

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Intensive chemotherapy with and without cranial radiation for Burkitt leukemia and lymphoma: final results of Cancer and Leukemia Group B Study 9251.

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Intensive induction is effective in selected octogenarian acute myeloid leukemia patients: prognostic significance of karyotype and selected molecular markers used in the European LeukemiaNet classification

scientific article published on 04 October 2013

Interleukin-4 and interleukin-5 map to human chromosome 5 in a region encoding growth factors and receptors and are deleted in myeloid leukemias with a del(5q).

scientific article published in February 1989

Interphase cytogenetic analysis detects minimal residual disease in a case of acute lymphoblastic leukemia and resolves the question of origin of relapse after allogeneic bone marrow transplantation

scientific article published on 01 March 1991

Irreversible myelosuppression after fludarabine-melphalan conditioning: observations in patients with graft rejection

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Is modulation of multidrug resistance a viable strategy for acute myeloid leukemia?

scientific article published on 01 March 2003

Is secondary leukemia an independent poor prognostic factor in acute myeloid leukemia?

scientific article published on March 2007

Is there a best TKI for chronic phase CML?

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Isolated trisomy of chromosomes 8, 11, 13 and 21 is an adverse prognostic factor in adults with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B 8461.

scientific article published in November 2002

Lenalidomide consolidation benefits patients with CLL receiving chemoimmunotherapy: results for CALGB 10404 (Alliance)

Limited efficacy of a four-day course of high-dose cytosine arabinoside in the treatment of poor-risk patients with acute nonlymphocytic leukemia

scientific article published on 01 January 1986

Lineage involvement by BCR/ABL in Ph+ lymphoblastic leukemias: chronic myelogenous leukemia presenting in lymphoid blast vs Ph+ acute lymphoblastic leukemia.

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Lineage specific treatment of adult patients with acute lymphoblastic leukemia in first remission with anti-B4-blocked ricin or high-dose cytarabine: Cancer and Leukemia Group B Study 9311.

scientific article published in March 2003

Listeriosis after 2-Chlorodeoxyadenosine Treatment

scientific article published on 01 March 1993

Long Term Outcome of Patients with Acute Myelogenous Leukemia: The Role of Maintenance Therapy, Consolidation Therapy and the Predictive Value of Twoin vitroAssays

scientific article published on 01 May 1993

Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia

scientific article published on March 2017

Long-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial

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Long-term disease-free survivors with cytogenetically normal acute myeloid leukemia and MLL partial tandem duplication: a Cancer and Leukemia Group B study

scientific article published on 6 March 2007

Long-term outcomes for newly-diagnosed multiple myeloma patients treated with pegylated liposomal doxorubicin and bortezomib: final results of CALGB (Alliance) 10301, a multicentre phase II study

scientific article published on 22 July 2015

Long-term outcomes with frontline nilotinib versus imatinib in newly diagnosed chronic myeloid leukemia in chronic phase: ENESTnd 10-year analysis

scientific article published on 07 January 2021

Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS)

scientific article published on 2 August 2010

Long-term survival of patients with intermediate and high grade lymphoma treated with COMLA/ABP

scientific article published on 01 February 1990

Long‐term follow‐up of cancer and leukemia group B studies in acute myeloid leukemia ⬇️

scientific article published on 01 December 1997

Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia

scientific article published on 9 August 2011

Low incidence of TAL1 gene rearrangements in adult acute lymphoblastic leukemia: A cancer and leukemia group B study (8762)

scientific article published on 01 April 1995

Low-dose interleukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leukemia in first complete remission: Cancer and Leukemia Group B Study 9720.

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MDM2 SNP309 and TP53 Arg72Pro interact to alter therapy-related acute myeloid leukemia susceptibility

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MDR1 transcript levels as an indication of resistant disease in acute myelogenous leukaemia.

scientific article published in July 1990

Maintenance therapy with decitabine in younger adults with acute myeloid leukemia in first remission: a phase 2 Cancer and Leukemia Group B Study (CALGB 10503).

scientific article published on 13 September 2016

Metastatic adenocarcinoma arising in a congenital foregut cyst of the esophagus: a case report with review of the literature.

scientific article published on February 1998

MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia

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MicroRNA expression in cytogenetically normal acute myeloid leukemia

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MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia

scholarly article

Midostaurin in patients with acute myeloid leukemia and FLT3-TKD mutations: a subanalysis from the RATIFY trial

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Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

scientific article published on 23 June 2017

Mitoxantrone and 5-azacytidine for refractory/relapsed ANLL or CML in blast crisis: a leukemia intergroup study

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Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1-1.5 Mb and preparation of a PAC-based physical map.

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Morphology in Ki-1(CD30)-positive non-Hodgkin's lymphoma is correlated with clinical features and the presence of a unique chromosomal abnormality, t(2;5)(p23;q35)

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Multiple unrelated clonal abnormalities in host bone marrow cells after allogeneic stem cell transplantation

scientific article published in May 2004

Mutations of the Wilms tumor 1 gene (WT1) in older patients with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

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Myeloid Leukemia After Cytotoxic Therapy and Other Hematotoxins

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Myeloid leukemia after hematotoxins

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Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801.

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Neurocysticercosis Coincident with Acute Myeloid Leukemia: A Case Report.

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Neutrophil-assisted DNA synthesis by human lymphocytes in response to mevalonic acid; enhancement by cytochalasin B

scientific article published on 01 October 1983

New high-performance liquid chromatographic assay for plasma doxorubicin

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Next-generation sequencing reveals clinically actionable molecular markers in myeloid sarcoma

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Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is active in patients with imatinib-resistant or -intolerant accelerated-phase chronic myelogenous leukemia

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Nilotinib in imatinib-resistant or imatinib-intolerant patients with chronic myeloid leukemia in chronic phase: 48-month follow-up results of a phase II study.

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Nilotinib is active in chronic and accelerated phase chronic myeloid leukemia following failure of imatinib and dasatinib therapy.

scientific article

Nilotinib is associated with a reduced incidence of BCR-ABL mutations vs imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase

scientific article published on 15 March 2013

Nilotinib is effective in imatinib-resistant or -intolerant patients with chronic myeloid leukemia in blastic phase.

scientific article

Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results

scientific article published on 22 November 2010

Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia

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Nilotinib versus imatinib for the treatment of patients with newly diagnosed chronic phase, Philadelphia chromosome-positive, chronic myeloid leukaemia: 24-month minimum follow-up of the phase 3 randomised ENESTnd trial

scientific article published on 17 August 2011

Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up.

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Nonrandom chromosome abnormalities in angioimmunoblastic lymphadenopathy ⬇️

scientific article published on October 1, 1982

Oral Debio1143 (AT406), an antagonist of inhibitor of apoptosis proteins, combined with daunorubicin and cytarabine in patients with poor-risk acute myeloid leukemia--results of a phase I dose-escalation study

scientific article published on 05 March 2015

Outcome for pediatric acute promyelocytic leukemia patients at Children's Oncology Group sites on the Leukemia Intergroup Study CALGB 9710 (Alliance)

scientific article published on 04 November 2018

Outcome of adolescents and young adults with acute myeloid leukemia treated on COG trials compared to CALGB and SWOG trials

scientific article published on 19 September 2013

Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: a cancer and leukemia group B study

scientific article published on 8 November 2004

Outcomes of patients with AML and MDS who relapse or progress after reduced intensity allogeneic hematopoietic cell transplantation

scientific article published on 10 September 2007

Overexpression and knockout of miR-126 both promote leukemogenesis

scientific article

Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study

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P-glycoprotein (Pgp) modulation in untreated acute myeloid leukemia (AML): Cancer and Leukemia Group B (CALGB) trials in younger and older adults

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P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808

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Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study

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Patients with chronic lymphocytic leukemia with high-risk genomic features have inferior outcome on successive Cancer and Leukemia Group B trials with alemtuzumab consolidation: subgroup analysis from CALGB 19901 and CALGB 10101.

scientific article published on 09 May 2013

Patients' perspectives on the definition of cure in chronic myeloid leukemia

scientific article published on 28 March 2019

Patterns and kinetics of T-cell chimerism after allo transplant with alemtuzumab-based conditioning: mixed chimerism protects from GVHD, but does not portend disease recurrence

scientific article published in November 2009

Performance Status and Comorbidity Predict Transplant-Related Mortality After Allogeneic Hematopoietic Cell Transplantation

scientific article published on 01 September 2006

Persistence of the 8;21 translocation in patients with acute myeloid leukemia type M2 in long-term remission.

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Perspectives on the treatment of chronic phase and advanced phase CML and Philadelphia chromosome positive ALL(1).

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Pharmacokinetics, pharmacodynamics and adherence to oral topotecan in myelodysplastic syndromes: a Cancer and Leukemia Group B study

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Phase 1 dose-finding study of rebastinib (DCC-2036) in patients with relapsed chronic myeloid leukemia and acute myeloid leukemia

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Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome.

scientific article published on 13 May 2009

Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720.

scientific article published in August 2002

Phase I study of busulfan, cyclophosphamide, and timed sequential escalating doses of cytarabine followed by bone marrow transplantation

scientific article published on 01 January 1992

Phase I study of dose-escalated busulfan with fludarabine and alemtuzumab as conditioning for allogeneic hematopoietic stem cell transplant: reduced clearance at high doses and occurrence of late sinusoidal obstruction syndrome/veno-occlusive diseas

scientific article published on 4 October 2010

Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia: pharmacokinetics, pharmacodynamics, and clinical activity

scientific article published on 11 April 2005

Phase I study of the ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehyde-thiosemicarbazone (3-AP) in combination with high dose cytarabine in patients with advanced myeloid leukemia.

scientific article

Phase I trial of a genetically engineered interleukin-2 fusion toxin (DAB486IL-2) as a 6 hour intravenous infusion in patients with hematologic malignancies.

scientific article

Phase I trial of maintenance selinexor after allogeneic hematopoietic stem cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndrome

scientific article published on 06 May 2020

Phase I-II study of clofarabine-melphalan-alemtuzumab conditioning for allogeneic hematopoietic cell transplantation

scientific article

Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in O

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Phase II study of nilotinib in patients with relapsed or refractory Philadelphia chromosome--positive acute lymphoblastic leukemia

scientific article

Phase II study of the oral MEK inhibitor selumetinib in advanced acute myelogenous leukemia: a University of Chicago phase II consortium trial.

scientific article

Phase II study of troxacitabine, a novel dioxolane nucleoside analog, in patients with untreated or imatinib mesylate-resistant chronic myelogenous leukemia in blastic phase

scientific article published in December 2003

Phase II trial of oral aminopterin for adults and children with refractory acute leukemia

scientific article

Phase III study of PSC-833 (valspodar) in combination with vincristine, doxorubicin, and dexamethasone (valspodar/VAD) versus VAD alone in patients with recurring or refractory multiple myeloma (E1A95): a trial of the Eastern Cooperative Oncology Gr

scientific article published in February 2006

Phase III trial of fludarabine plus cyclophosphamide compared with fludarabine for patients with previously untreated chronic lymphocytic leukemia: US Intergroup Trial E2997.

scientific article

Polymorphisms in the MLL breakpoint cluster region (BCR)

scientific article published on 29 March 2003

Poor prognosis acute myelogenous leukemia: 1 – response to treatment with high dose cytarabine/mitoxantrone/ethyol @ (Amifostine)

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Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase

scientific article published on 30 December 2011

Positron Emission Tomography–Computed Tomography Imaging of a Patient With Several Myeloid Sarcomas WithFLT3-ITD andNPM1Mutations

scientific article published on 14 April 2014

Postremission therapy with low-dose interleukin 2 with or without intermediate pulse dose interleukin 2 therapy is well tolerated in elderly patients with acute myeloid leukemia: Cancer and Leukemia Group B study 9420.

scientific article

Pre-transplant ganciclovir and post transplant high-dose valacyclovir reduce CMV infections after alemtuzumab-based conditioning

scientific article published in February 2006

Prediction of outcomes in patients with Ph+ chronic myeloid leukemia in chronic phase treated with nilotinib after imatinib resistance/intolerance.

scientific article

Pretreatment C-reactive protein is a predictor for outcomes after reduced-intensity allogeneic hematopoietic cell transplantation

scientific article

Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

scientific article (publication date: 15 December 2002)

Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461.

scientific article published on 7 March 2006

Prevalence of the inactivating 609C-->T polymorphism in the NAD(P)H:quinone oxidoreductase (NQO1) gene in patients with primary and therapy-related myeloid leukemia.

scientific article published in July 1999

Processing of bone marrow for transplantation: development of a mononuclear cell enrichment protocol

scientific article published on 01 January 1994

Prognosis and therapy when acute promyelocytic leukemia and other "good risk" acute myeloid leukemias occur as a therapy-related myeloid neoplasm.

scientific article

Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia

scientific article

Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study

scientific article published in August 2005

Prognostic implications of morphology and karyotype in primary myelodysplastic syndromes

scientific article published on 01 June 1986

Prognostic importance of MN1 transcript levels, and biologic insights from MN1-associated gene and microRNA expression signatures in cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study

scientific article

Prognostic importance of TLX1 (HOX11) oncogene expression in adults with T-cell acute lymphoblastic leukaemia

scientific article published in February 2004

Prognostic significance of additional cytogenetic abnormalities in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia treated with interferon-alpha: a Cancer and Leukemia Group B study.

scientific article published in July 2004

Prognostic significance of expression of a single microRNA, miR-181a, in cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

Prognostic significance of the European LeukemiaNet standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia

scientific article

Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B Study

scientific article published on 22 September 2008

Progress and challenges in the therapy of adult acute lymphoblastic leukemia.

scientific article

Prospective karyotype analysis in adult acute lymphoblastic leukemia: the cancer and leukemia Group B experience

scientific article published on 01 June 1999

Protooncogene expression and the clinical characteristics of acute nonlymphocytic leukemia: A Leukemia Intergroup pilot study

scientific article published in January 1989

Pseudo-Gaucher histiocytes identified up to 1 year after transplantation for CML are BCR/ABL-positive

scientific article published on 01 February 1998

Psychosocial adjustment of patients and caregivers prior to allogeneic bone marrow transplantation

scientific article published on 01 June 2001

Quality of life in patients with newly diagnosed chronic phase chronic myeloid leukemia on imatinib versus interferon alfa plus low-dose cytarabine: results from the IRIS Study

scientific article published in June 2003

Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia

scientific article

Quantitative real-time RT-PCR monitoring of BCR-ABL in chronic myelogenous leukemia shows lack of agreement in blood and bone marrow samples

scientific article published on 01 May 2006

RAS, FLT3, and TP53 mutations in therapy-related myeloid malignancies with abnormalities of chromosomes 5 and 7.

scientific article published in March 2004

RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia.

scientific article published on 21 March 2018

RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures

scientific article

Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

scientific article

Randomized trial of 10 days of decitabine ± bortezomib in untreated older patients with AML: CALGB 11002 (Alliance)

scholarly article published 26 December 2018

Rapid Donor Identification Improves Survival in High-Risk First-Remission Patients With Acute Myeloid Leukemia

scientific article published on 27 January 2020

Rapid presumptive diagnosis of hantavirus cardiopulmonary syndrome by peripheral blood smear review.

scientific article

Rapid response of B-cell prolymphocytic leukemia to 2-chlorodeoxyadenosine ⬇️

scientific article published on 01 November 1992

Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II

scientific article published on 01 December 1993

Recombinant interleukin-2 in patients aged younger than 60 years with acute myeloid leukemia in first complete remission: results from Cancer and Leukemia Group B 19808

scientific article

Recurrent fungal pneumonias in patients with acute nonlymphocytic leukemia undergoing multiple courses of intensive chemotherapy

scientific article published on 01 February 1988

Reduced intensity haplo plus single cord transplant compared to double cord transplant: improved engraftment and graft-versus-host disease-free, relapse-free survival.

scientific article published on 11 February 2016

Reduced-Intensity Allogeneic Transplant for Acute Myeloid Leukemia and Myelodysplastic Syndrome Using Combined CD34-Selected Haploidentical Graft and a Single Umbilical Cord Unit Compared with Matched Unrelated Donor Stem Cells in Older Adults

scientific article

Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions

scientific article published on 5 October 2011

Refinement of the Smallest Commonly Deleted Segment of Chromosome 20 in Malignant Myeloid Diseases and Development of a PAC-Based Physical and Transcription Map

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Refractory cytopenia with multilineage dysplasia: further characterization of an 'unclassifiable' myelodysplastic syndrome.

scientific article

Relapse of Hodgkin's Disease After 14 Years of Complete Remission

scientific article

Relationship between obesity and clinical outcome in adults with acute myeloid leukemia: A pooled analysis from four CALGB (alliance) clinical trials

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Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): results from CALGB 8461.

scientific article published in March 2004

Response to 5-azacytidine in patients with refractory acute nonlymphocytic leukemia and association with chromosome findings ⬇️

scientific article published on 01 June 1982

Results from a multidisciplinary clinic guided by geriatric assessment before stem cell transplantation in older adults

scientific article published on 01 November 2019

Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

scientific article published on December 2003

Risk factors for severe neuropsychiatric toxicity in patients receiving interferon alfa-2b and low-dose cytarabine for chronic myelogenous leukemia: analysis of Cancer and Leukemia Group B 9013

scientific article

Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study

scientific article

Safety and efficacy of romiplostim in patients with lower-risk myelodysplastic syndrome and thrombocytopenia

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Safety and efficacy of switching to nilotinib 400 mg twice daily for patients with chronic myeloid leukemia in chronic phase with suboptimal response or failure on front-line imatinib or nilotinib 300 mg twice daily

scientific article published on 14 February 2014

Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy

scientific article

Selective inhibition of FLT3 by gilteritinib in relapsed or refractory acute myeloid leukaemia: a multicentre, first-in-human, open-label, phase 1-2 study

scientific article

Sequential multiagent chemotherapy is not superior to high-dose cytarabine alone as postremission intensification therapy for acute myeloid leukemia in adults under 60 years of age: Cancer and Leukemia Group B Study 9222.

scientific article published on 30 November 2004

Short remission durations in therapy-related leukemia despite cytogenetic complete responses to high-dose cytarabine

scientific article published on 01 October 1988

Shortcomings in the clinical evaluation of new drugs: acute myeloid leukemia as paradigm

scientific article

Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia

scientific article published on 12 March 2009

Specific chromosomal abnormalities in acute nonlymphocytic leukemia correlate with drug susceptibility in vivo.

scientific article

Successful allogeneic transplantation of patients with suspected prior invasive mold infection

scientific article published on 01 September 2007

Successful autologous stem cell collection in patients with chronic myeloid leukemia in complete cytogenetic response, with quantitative measurement of BCR-ABL expression in blood, marrow, and apheresis products

scientific article

Successful treatment of angioimmunoblastic lymphadenopathy with dysproteinemia with fludarabine

scientific article published on 01 September 1996

Survival advantage from imatinib compared with the combination interferon- plus cytarabine in chronic-phase chronic myelogenous leukemia: historical comparison between two phase 3 trials

scientific article published on 20 April 2006

TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

Telomere Length Recovery: A Strong Predictor of Overall Survival in Acute Promyelocytic Leukemia

scientific article published on 16 September 2016

The DNA synthetic response of normal and abnormal human lymphocytes to mevalonic acid: the role of granulocytes as a helper population

scientific article published on September 1984

The MLL partial tandem duplication in adults aged 60 years and older with de novo cytogenetically normal acute myeloid leukemia

scientific article published on 7 February 2012

The Relationship of the in vivo Cell Cycle Characteristics and Treatment Outcome in Acute Myelogenous Leukemia to the Expression of the FMS and MYC Proto-Oncogenes

scientific article published on 01 July 1994

The evolving challenge of therapy-related myeloid neoplasms

scientific article published on October 2013

The impact of initial fludarabine therapy on transformation to Richter syndrome or prolymphocytic leukemia in patients with chronic lymphocytic leukemia: analysis of an intergroup trial (CALGB 9011).

scientific article published on 8 September 2012

The predictive value of initial cytogenetic studies in 148 adults with acute nonlymphocytic leukemia: A 12-year study (1970–1982)

scientific article published on 01 November 1983

The relationship between secondary chromosomal abnormalities and blast transformation in chronic myelogenous leukemia

scientific article published on 01 April 1995

The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in adults: an evidence-based review.

scientific article

The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukemia: update of the 2006 evidence-based review

The serial study of c-myc expression in bone marrow biopsy specimens during treatment for acute myelogenous leukaemia

scientific article published on 01 January 1993

The spectrum of somatic mutations in high-risk acute myeloid leukaemia with -7/del(7q).

scientific article

The t(2;5)(p23;q35): a recurring chromosomal abnormality in Ki-1-positive anaplastic large cell lymphoma.

scientific article published on December 1989

The treatment of patients with newly diagnosed poor prognosis acute myelogenous leukaemia: response to treatment and treatment failure

scientific article

Therapy-Related Myelodysplastic Syndrome

scientific article published on 01 February 2007

Therapy-related acute lymphoblastic leukemia is a distinct entity with adverse genetic features and clinical outcomes

scientific article published on 01 December 2019

Therapy-related myeloid leukaemia: A model for leukemogenesis in humans

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Therapy-related myeloid leukemia.

scientific article published on August 2008

Therapy-related myeloid leukemias are observed in patients with chronic lymphocytic leukemia after treatment with fludarabine and chlorambucil: results of an intergroup study, cancer and leukemia group B 9011.

scientific article published in September 2002

Therapy-related myeloid sarcoma with anNPM1mutation

scientific article published on 21 September 2010

Three new drugs for acute lymphoblastic leukemia: nelarabine, clofarabine, and forodesine.

scientific article published on December 2007

Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q)

scientific article (publication date: 15 January 2001)

Transplantation in adults with relapsed/refractory acute lymphoblastic leukemia who are treated with blinatumomab from a phase 3 study

scientific article published on 21 August 2019

Treatment by design in leukemia, a meeting report, Philadelphia, Pennsylvania, December 2002.

scientific article published in December 2003

Treatment of Acute Promyelocytic Leukemia in Adults

scientific article published on 01 November 2018

Treatment of acute promyelocytic leukemia in older patients: recommendations of an International Society of Geriatric Oncology (SIOG) task force

scientific article published on 06 April 2020

Treatment of myelodysplastic syndrome with 2 schedules and doses of oral topotecan: a randomized phase 2 trial by the Cancer and Leukemia Group B (CALGB 19803).

scientific article

Treatment of relapsed chronic lymphocytic leukemia by 72-hour continuous infusion or 1-hour bolus infusion of flavopiridol: results from Cancer and Leukemia Group B study 19805.

scientific article

Treatment of the Chronic Phase of Chronic Myeloid Leukemia with an Intermittent Schedule of Recombinant Interferon Alfa-2b and Cytarabine: Results from CALGB Study 9013 ⬇️

scientific article published on January 1, 2003

Treatment of therapy-related myeloid neoplasms with high-dose cytarabine/mitoxantrone followed by hematopoietic stem cell transplant

scientific article

Treatment-influenced associations of PML-RARα mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia

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Trisomy 6: a recurring cytogenetic abnormality associated with marrow hypoplasia

scientific article published on 01 March 1991

Unexpected Toxicities When Nivolumab Was Given as Maintenance Therapy following Allogeneic Stem Cell Transplantation

scientific article published on 01 February 2020

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.

scientific article published on 17 January 2012

Value of immunophenotype in intensively treated adult acute lymphoblastic leukemia: cancer and leukemia Group B study 8364.

scientific article published on June 1999

Variations of the ataxia telangiectasia mutated gene in patients with chronic lymphocytic leukemia lack substantial impact on progression-free survival and overall survival: a Cancer and Leukemia Group B study

scientific article published on 02 June 2012

Vatalanib population pharmacokinetics in patients with myelodysplastic syndrome: CALGB 10105 (Alliance)

scientific article

What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children's Cancer Group and Cancer and Leukemia Group B studies

scientific article published on 23 May 2008

Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study

scientific article

`Golden Tongue' Syndrome Caused by Ramichloridium schulzeri

scientific article published on 01 July 1985

c-myc and c-myb expression in acute myelogenous leukemia

scientific article published on 01 October 1992

der(5)t(5;7)(q11.2;p11.2): A new recurring abnormality in malignant myeloid disorders

scientific article published on 01 January 1989

dic(5;17): A recurring abnormality in malignant myeloid disorders associated with mutations ofTP53 ⬇️

scientific article published on 01 November 1997

inv(16)/t(16;16) acute myeloid leukemia with non-type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations

scientific article published on 16 November 2012

miR-155 expression is associated with chemoimmunotherapy outcome and is modulated by Bruton's tyrosine kinase inhibition with Ibrutinib.

scientific article published on 9 December 2014

miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia

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miR-3151 Interplays With its Host Gene BAALC and Independently Impacts on Outcome of Older Patients With Cytogenetically Normal Acute Myeloid Leukemia by Direct Deregulation of TP53

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miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia

scientific article

miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia.

scientific article published on 24 June 2013

t(1;3)(p36;p21) is a recurring therapy-related translocation

scientific article published on 01 June 2002

t(3;21)(q26;q22): a recurring chromosomal abnormality in therapy-related myelodysplastic syndrome and acute myeloid leukemia

scientific article published in December 1990

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