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List of works by Robert P. Coppes

A new CT-based method to quantify radiation-induced lung damage in patients

scientific article published on 04 August 2015

ACE inhibition attenuates radiation-induced cardiopulmonary damage.

scientific article published on 25 November 2014

Autophagy induction during stem cell activation plays a key role in salivary gland self-renewal

scientific article published on 19 May 2021

Bath and shower effects in the rat parotid gland explain increased relative risk of parotid gland dysfunction after intensity-modulated radiotherapy

scientific article published on 01 July 2009

Bone marrow-derived macrophages incorporate into the endothelium and influence vascular and renal function after irradiation

scientific article published on 25 June 2014

Can we rescue salivary gland function after irradiation?

scientific article

Cancer stem cells with increased metastatic potential as a therapeutic target for esophageal cancer.

scientific article

Cellular senescence contributes to radiation-induced hyposalivation by affecting the stem/progenitor cell niche

scientific article published on 14 October 2020

Changes in expression of injury after irradiation of increasing volumes in rat lung.

scientific article published in April 2007

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

scientific article published on 20 July 2018

Clinical management of salivary gland hypofunction and xerostomia in head-and-neck cancer patients: successes and barriers.

scientific article

Co-released adrenaline markedly facilitates noradrenaline overflow through prejunctional beta 2-adrenoceptors during swimming exercise.

scientific article published in February 1995

Comments on: Extended-term effects of head and neck irradiation in a rodent. Eur J Cancer 2001, 37, 1938-1945

scientific article published on 01 April 2002

Comparison of radiosensitivity of rat parotid and submandibular glands after different radiation schedules

scientific article published in June 2002

Concise Review: Adult Salivary Gland Stem Cells and a Potential Therapy for Xerostomia ⬇️

scientific article published on April 1, 2013

Current and Future Perspectives of the Use of Organoids in Radiobiology

scientific article published on 09 December 2020

Current ideas to reduce or salvage radiation damage to salivary glands

scientific article published on 28 February 2014

Cytokine treatment improves parenchymal and vascular damage of salivary glands after irradiation

scientific article

Decreasing Irradiated Rat Lung Volume Changes Dose-Limiting Toxicity From Early to Late Effects

scientific article published on 28 September 2015

Defects in muscarinic receptor-coupled signal transduction in isolated parotid gland cells after in vivo irradiation: evidence for a non-DNA target of radiation

scientific article published in February 2005

Development of a facility for high-precision irradiation of cells with carbon ions

scientific article published on 01 January 2011

Dose-volume effects in the rat cervical spinal cord after proton irradiation

scientific article published on 01 January 2002

Dysfunctional presynaptic alpha 2-adrenoceptors expose facilitatory beta 2-adrenoceptors in the vasculature of spontaneously hypertensive rats

scientific article published on February 11, 1992

Early to late sparing of radiation damage to the parotid gland by adrenergic and muscarinic receptor agonists

scientific article

Effects of Radioiodine Treatment on Salivary Gland Function in Patients with Differentiated Thyroid Carcinoma: A Prospective Study.

scientific article published on 23 June 2016

Endoglin haploinsufficiency attenuates radiation-induced deterioration of kidney function in mice

scientific article published on 9 July 2013

Enhanced proliferation of acinar and progenitor cells by prophylactic pilocarpine treatment underlies the observed amelioration of radiation injury to parotid glands.

scientific article published on 10 January 2009

FLASH radiotherapy International Workshop

scientific article published on 21 August 2019

Hedgehog Pathway as a Potential Intervention Target in Esophageal Cancer

scientific article published on 13 June 2019

Heterogeneity of prejunctional neuropeptide Y receptors inhibiting noradrenaline overflow in the portal vein of freely moving rats

scientific article published on August 1994

High and low LET radiation differentially induce normal tissue damage signals.

scientific article published on 13 January 2012

Human Salivary Gland Stem Cells Functionally Restore Radiation Damaged Salivary Glands.

scientific article

In vitro biological response of cancer and normal tissue cells to proton irradiation not affected by an added magnetic field

scientific article published on 11 May 2019

Influence of adjacent low-dose fields on tolerance to high doses of protons in rat cervical spinal cord

scientific article published on 01 March 2006

Irradiation of rat brain reduces P-glycoprotein expression and function.

scientific article published on 3 July 2007

Isolation of Mouse Salivary Gland Stem Cells ⬇️

scientific article published on February 8, 2011

Keratinocyte growth factor prevents radiation damage to salivary glands by expansion of the stem/progenitor pool

scientific article published on 31 July 2008

Lack of DNA Damage Response at Low Radiation Doses in Adult Stem Cells Contributes to Organ Dysfunction

scientific article published on 22 August 2018

Loco-regional differences in pulmonary function and density after partial rat lung irradiation.

scientific article published in October 2003

Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals

scientific article published on 22 December 2015

Lung irradiation induces pulmonary vascular remodelling resembling pulmonary arterial hypertension

scientific article published on 26 December 2011

Macrophages Come To The Rescue

scientific article published on 01 December 2020

Micro cone beam computed tomography for sensitive assessment of radiation-induced late lung toxicity in preclinical models

scientific article published on 27 May 2019

Mobilization of bone marrow stem cells by granulocyte colony-stimulating factor ameliorates radiation-induced damage to salivary glands

scientific article published in March 2006

On the mechanism of salivary gland radiosensitivity.

scientific article

Optimum dose range for the amelioration of long term radiation-induced hyposalivation using prophylactic pilocarpine treatment.

scientific article published on 19 November 2007

Oral sequelae of head and neck radiotherapy.

scientific article

Parotid and submandibular/sublingual salivary flow during high dose radiotherapy

scientific article published on 01 December 2001

Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening

scientific article published on 31 October 2020

Patient-derived tumor organoids for prediction of cancer treatment response

scientific article published on 30 June 2018

Physiological interaction of heart and lung in thoracic irradiation.

scientific article published on 11 September 2012

Post-irradiation dietary vitamin E does not affect the development of radiation-induced lung damage in rats.

scientific article published in July 2004

Pre- and postganglionic stimulation-induced noradrenaline overflow is markedly facilitated by a prejunctional beta 2-adrenoceptor-mediated control mechanism in the pithed rat.

scientific article published on June 1994

Prediction of response to radiotherapy in the treatment of esophageal cancer using stem cell markers

scientific article published on 14 May 2013

Prejunctional histamine H3-receptors inhibit electrically evoked endogenous noradrenaline overflow in the portal vein of freely moving rats

scientific article published on 01 February 1997

Preoperative irradiation with 5 x 5 Gy in a murine isolated colon loop model does not cause anastomotic weakening after colon resection

scientific article published on 16 July 2008

Preservation of the rat parotid gland function after radiation by prophylactic pilocarpine treatment: radiation dose dependency and compensatory mechanisms

scientific article published on 01 September 1999

Prevention and treatment of the consequences of head and neck radiotherapy.

scientific article

Protection of salivary function by concomitant pilocarpine during radiotherapy: a double-blind, randomized, placebo-controlled study

scientific article published on 14 September 2007

Pulmonary radiation injury: identification of risk factors associated with regional hypersensitivity

scientific article

Purification and ex vivo expansion of fully functional salivary gland stem cells

scientific article published on 23 October 2014

Quantifying local radiation-induced lung damage from computed tomography

scientific article published on 01 February 2010

Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials

scientific article published on 17 June 2009

Radiation and transforming growth factor-beta cooperate in transcriptional activation of the profibrotic plasminogen activator inhibitor-1 gene.

scientific article published on August 2005

Radiation damage to the heart enhances early radiation-induced lung function loss.

scientific article

Radiation-induced apoptosis in relation to acute impairment of rat salivary gland function

scientific article published on 01 June 1998

Radioprotective effect of amifostine on parotid gland functioning is region dependent

scientific article

Regeneration of irradiated salivary glands with stem cell marker expressing cells.

scientific article

Regional differences in radiosensitivity across the rat cervical spinal cord

scientific article published on 01 February 2005

Relation between radiation-induced whole lung functional loss and regional structural changes in partial irradiated rat lung.

scientific article published in April 2006

Rescue of salivary gland function after stem cell transplantation in irradiated glands

scientific article published on 30 April 2008

Role of glial-cell-derived neurotrophic factor in salivary gland stem cell response to irradiation

scientific article published on 4 August 2017

Salisphere derived c-Kit+ cell transplantation restores tissue homeostasis in irradiated salivary gland

scientific article published on 13 June 2013

Salivary Gland Stem Cells Age Prematurely in Primary Sjögren's Syndrome

scientific article published on 01 January 2019

Secondary radiation damage as the main cause for unexpected volume effects: a histopathologic study of the parotid gland

scientific article published on 13 October 2005

Sialogogue-related radioprotection of salivary gland function: the degranulation concept revisited

scientific article published on 01 September 1997

Similar ex vivo expansion and post-irradiation regenerative potential of juvenile and aged salivary gland stem cells.

scientific article

Sparing the region of the salivary gland containing stem cells preserves saliva production after radiotherapy for head and neck cancer.

scientific article published on September 2015

Stem cell therapies for the treatment of radiation-induced normal tissue side effects

scientific article

Stem cell therapy to reduce radiation-induced normal tissue damage

scientific article published on April 2009

Strong activation of vascular prejunctional beta 2-adrenoceptors in freely moving rats by adrenaline released as a co-transmitter.

scientific article published in October 1993

TGFbeta-1 dependent fast stimulation of ATM and p53 phosphorylation following exposure to ionizing radiation does not involve TGFbeta-receptor I signalling.

scientific article

Targeting Stem Cells in Radiation Oncology.

scientific article published on 28 March 2017

Thalidomide ameliorates inflammation and vascular injury but aggravates tubular damage in the irradiated mouse kidney

scientific article published on July 2014

The In Vitro Response of Tissue Stem Cells to Irradiation With Different Linear Energy Transfers.

scientific article published on 12 February 2016

The impact of heart irradiation on dose-volume effects in the rat lung

scientific article published on 01 October 2007

Three-dimensional dose distribution for partial irradiation of rat parotid glands with 200kV X-rays

scientific article published in September 2003

Transforming growth factor-beta plasma dynamics and post-irradiation lung injury in lung cancer patients.

scientific article published in May 2004

Understanding mechanisms yields novel approaches to reduce radiotherapy-related xerostomia.

scientific article published on February 2017

Unexpected changes of rat cervical spinal cord tolerance caused by inhomogeneous dose distributions

scientific article published on 01 September 2003

Variability of flow rate when collecting stimulated human parotid saliva

scientific article published on 01 October 2005

Volume effects and region-dependent radiosensitivity of the parotid gland

scientific article published on 01 July 2005

Volume-dependent expression of in-field and out-of-field effects in the proton-irradiated rat lung

scientific article published on 24 May 2011

ΔNp73 enhances promoter activity of TGF-β induced genes

scientific article

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