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List of works by Joseph Keane

A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.

scientific article published on February 2016

A TNF-regulated recombinatorial macrophage immune receptor implicated in granuloma formation in tuberculosis

scientific article

A caspase-independent pathway mediates macrophage cell death in response to Mycobacterium tuberculosis infection.

scientific article published on 5 February 2007

A pulmonary mass with invasion into the heart

scientific article published on 17 October 2008

Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

article

All-trans Retinoic Acid Augments Autophagy during Intracellular Bacterial Infection

Alveolar macrophages contribute to respiratory tolerance by inducing FoxP3 expression in naive T cells

scientific article

An unusual lung mass post stem cell transplantation

scientific article published on 4 July 2014

Anal fistula: an unusual presentation of tuberculosis in a migrant health care professional

scientific article published on 01 December 2009

Antigen stimulation of peripheral blood mononuclear cells from Mycobacterium bovis infected cattle yields evidence for a novel gene expression program

scientific article

Apoptosis genes in human alveolar macrophages infected with virulent or attenuated Mycobacterium tuberculosis: a pivotal role for tumor necrosis factor

scientific article published on 14 May 2003

Beta-chemokines are induced by Mycobacterium tuberculosis and inhibit its growth

scientific article published on April 2002

Bystander Macrophage Metabolic Shift after <i>Mycobacterium tuberculosis</i> Infection

scientific article published on 01 December 2020

Cause or Effect? The Elusive Role of Regulatory T Cells in Tuberculosis

scientific article published on 01 July 2018

Cellular targeting and trafficking of drug delivery systems for the prevention and treatment of MTb.

scientific article published on 14 January 2011

Cigarette Smoking Impairs the Bioenergetic Immune Response to Mycobacterium tuberculosis Infection

scientific article published on 01 November 2018

Cigarette smoking impairs human pulmonary immunity to Mycobacterium tuberculosis

scientific article published on December 2014

Comparison of interferon {gamma} release assays and conventional screening tests before tumour necrosis factor {alpha} blockade in patients with inflammatory arthritis.

scientific article

Cutting Edge: Mycobacterium tuberculosis Induces Aerobic Glycolysis in Human Alveolar Macrophages That Is Required for Control of Intracellular Bacillary Replication

scientific article

Development of a simple, sensitive, rapid test which discriminates BCG-vaccinated from Mycobacterium bovis-infected cattle.

scientific article published on 8 August 2008

EBUS-TBNA performs well in the diagnosis of isolated thoracic tuberculous lymphadenopathy

scientific article published on 01 January 2011

Editorial: Tregs and BCG-dangerous liaisons in TB

scientific article published on 01 December 2010

Educational case: dysphagia caused by lymphadenopathy--what is the differential diagnosis?

scientific article published in December 2007

Epigenetic induction of CD1d expression primes lung cancer cells for killing by invariant natural killer T cells

scientific article published on 12 February 2018

First Case of Multidrug Resistant Spinal TB in Ireland.

scientific article

First Steps in Biomarker Assessment for Reactivation Risk in Latent Tuberculosis Infection.

scientific article

Gene expression profiling of peripheral blood mononuclear cells (PBMC) from Mycobacterium bovis infected cattle after in vitro antigenic stimulation with purified protein derivative of tuberculin (PPD).

scientific article published on 19 June 2006

How tumour necrosis factor blockers interfere with tuberculosis immunity.

scientific article

Human Natural Killer cell expression of ULBP2 is associated with a mature functional phenotype.

scientific article published on 24 June 2016

IL-10 Blocks Phagosome Maturation inMycobacterium tuberculosis–Infected Human Macrophages ⬇️

scientific article published on October 1, 2010

Identification of Mycobacterium avium DNA sequences that encode exported proteins by using phoA gene fusions.

scientific article

Inhalable poly(lactic-co-glycolic acid) (PLGA) microparticles encapsulating all-trans-Retinoic acid (ATRA) as a host-directed, adjunctive treatment for Mycobacterium tuberculosis infection

scholarly article by Gemma O'Connor et al published January 2019 in European Journal of Pharmaceutics and Biopharmaceutics

Innate gene repression associated with Mycobacterium bovis infection in cattle: toward a gene signature of disease

scientific article

Inoculation site leprosy in a tattoo as a paradoxical reaction following tuberculosis treatment

scientific article published in May 2016

Interferon gamma release assays for the diagnosis of latent TB infection in HIV-infected individuals in a low TB burden country

scientific article

Intravesical bacille Calmette–Guérin-induced multiorgan failure after treatment for transitional cell carcinoma ⬇️

scientific article published on February 18, 2011

Left atrial invasion by pulmonary adenocarcinoma.

scientific article published on 12 March 2007

Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration.

scientific article published on March 2016

Modulating Iron for Metabolic Support of TB Host Defense

scientific article published on 15 October 2018

Molecular epidemiology of multi- and extensively-drug-resistant Mycobacterium tuberculosis in Ireland, 2001-2014.

scientific article

Mycobacterium avium complex pulmonary disease: characteristics and treatment in an Irish patient cohort

scientific article

Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21

scientific article published on 01 January 2020

Mycobacterium tuberculosis infection induces non-apoptotic cell death of human dendritic cells ⬇️

scientific article published on October 24, 2011

Networked T cell death following macrophage infection by Mycobacterium tuberculosis

scientific article

Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children

scientific article published in January 2017

Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children.

scientific article

Paradoxical reaction causing tuberculous arthritis and soft-tissue abscess in a non-HIV infected, lymphopenic, vitamin D deficient patient with disseminated tuberculosis. A coincidence or an immunological conundrum?

scientific article published on 22 December 2010

Persistent pleural effusions in primary systemic amyloidosis: etiology and prognosis.

scientific article published in September 2003

Phenolic Glycolipid Facilitates Mycobacterial Escape from Microbicidal Tissue-Resident Macrophages

scientific article published on 23 August 2017

Platelets and Tuberculosis: Small Cells, Not So Innocent Bystanders

scientific article published on 01 July 2018

Primary isoniazid resistance in Mycobacterium bovis disease: a prospect of concern

scientific article published on 01 July 2012

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages.

scientific article published on 3 February 2015

Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages

scientific article published on January 2015

Renal amyloidosis complicating multidrug-resistant tuberculosis

scientific article published in April 2017

Response: Disseminated tuberculosis

scientific article published on 8 February 2017

Severity of elastase-induced emphysema is decreased in tumor necrosis factor-alpha and interleukin-1beta receptor-deficient mice

scientific article published on 01 January 2002

Sharpening nature's tools for efficient tuberculosis control: A review of the potential role and development of host-directed therapies and strategies for targeted respiratory delivery

scientific article published on 2 May 2016

Should cigarette smoke exposure be a criterion to treat latent tuberculous infection?

scientific article published on 01 October 2010

T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis.

scientific article

TB osteomyelitis.

scientific article

TNF-blocking agents and tuberculosis: new drugs illuminate an old topic

scientific article

TNF-dependent BALB/c murine macrophage apoptosis following Mycobacterium tuberculosis infection inhibits bacillary growth in an IFN-gamma independent manner

scientific article published on 01 January 2002

Th1-Th2 polarisation and autophagy in the control of intracellular mycobacteria by macrophages.

scientific article published on 17 October 2008

The application of high-content analysis in the study of targeted particulate delivery systems for intracellular drug delivery to alveolar macrophages.

scientific article

The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples: an NTM-NET collaborative study

scientific article published on 18 April 2013

The immunoregulatory role of CD4+FoxP3+CD25−regulatory T cells in lungs of mice infected withBordetella pertussis

Therapeutic aerosol bioengineering of targeted, inhalable microparticle formulations to treat Mycobacterium tuberculosis (MTb).

scientific article

Treatment of Mycobacterium tuberculosis-Infected Macrophages with Poly(Lactic-Co-Glycolic Acid) Microparticles Drives NFκB and Autophagy Dependent Bacillary Killing

scientific article

Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent

scientific article (publication date: 11 October 2001)

Tuberculous dactylitis in the setting of low serum vitamin D: a case report

scientific article published on 28 May 2011

Tumor necrosis factor blockers and reactivation of latent tuberculosis

scientific article published on 16 July 2004

Tumor necrosis factor blockers influence macrophage responses to Mycobacterium tuberculosis

scientific article published in December 2008

Untreated chronic tuberculous salpingitis followed by successful in vitro fertilization conception and congenital tuberculosis

scientific article published on 31 January 2015

Usual interstitial pneumonitis responsive to corticosteroids following varicella pneumonia

scientific article published on 01 January 1998

Virulent Mycobacterium tuberculosis strains evade apoptosis of infected alveolar macrophages.

scientific article

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