List of works - Souad Najib

A Switch of G Protein-Coupled Receptor Binding Preference from Phosphoinositide 3-Kinase (PI3K)–p85 to Filamin A Negatively Controls the PI3K Pathway ⬇️

scientific article published on December 27, 2011

A gastrin precursor, gastrin-gly, upregulates VEGF expression in colonic epithelial cells through an HIF-1-independent mechanism

scientific article published on June 2010

Characterization of immortalized human dermal microvascular endothelial cells (HMEC-1) for the study of HDL functionality

scientific article published on 9 March 2018

Characterization of pancreastatin receptor and signaling in rat HTC hepatoma cells

scientific article published on 01 June 2000

Ecto-F1-ATPase/P2Y pathways in metabolic and vascular functions of high density lipoproteins.

scientific article

Ectopic adenine nucleotide translocase activity controls extracellular ADP levels and regulates the F1-ATPase-mediated HDL endocytosis pathway on hepatocytes.

scientific article published on 11 May 2017

Homocysteine thiolactone inhibits insulin signaling, and glutathione has a protective effect

scientific article published in August 2001

Homocysteine thiolactone inhibits insulin-stimulated DNA and protein synthesis: possible role of mitogen-activated protein kinase (MAPK), glycogen synthase kinase-3 (GSK-3) and p70 S6K phosphorylation

scientific article published in February 2005

Human leptin promotes survival of human circulating blood monocytes prone to apoptosis by activation of p42/44 MAPK pathway

scientific article published in December 2002

Identification of the F1-ATPase at the cell surface of colonic epithelial cells: role in mediating cell proliferation.

scientific article published on 10 October 2012

Insulin activates Gαil,2 protein in rat hepatoma (HTC) cell membranes

scientific article published on 01 January 1999

Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells.

scientific article published on 28 October 2010

Liraglutide improves hepatic steatosis and metabolic dysfunctions in a 3-week dietary mouse model of nonalcoholic steatohepatitis

scientific article published on 28 August 2019

Paclitaxel induces lymphatic endothelial cells autophagy to promote metastasis

scientific article published on 20 December 2019

Pancreastatin, a chromogranin A-derived peptide, inhibits DNA and protein synthesis by producing nitric oxide in HTC rat hepatoma cells.

scientific article published in July 2001

Pancreastatin. Biological effects and mechanisms of action

scientific article published on 01 January 2000

Phosphatidylinositol 3-kinase-dependent transcriptional silencing of the translational repressor 4E-BP1.

scientific article published on October 2008

Progastrin a new pro-angiogenic factor in colorectal cancer

scientific article published on 11 August 2014

Reprint of: Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin.

scientific article published on 08 October 2010

Role of Sam68 as an adaptor protein in signal transduction

scientific article

Role of leptin as an immunomodulator of blood mononuclear cells: mechanisms of action

scientific article

Role of leptin in the activation of immune cells.

scientific article published on 23 March 2010

Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling

scientific journal article

Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling

scientific article (publication date: 25 October 2001)

Sam68 is tyrosine phosphorylated and recruited to signalling in peripheral blood mononuclear cells from HIV infected patients

scientific article

The expression of Sam68, a protein involved in insulin signal transduction, is enhanced by insulin stimulation.

scientific article

eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells

scientific article published in February 2005

p68 Sam is a substrate of the insulin receptor and associates with the SH2 domains of p85 PI3K

scientific journal article

List of works by Souad Najib

A Switch of G Protein-Coupled Receptor Binding Preference from Phosphoinositide 3-Kinase (PI3K)–p85 to Filamin A Negatively Controls the PI3K Pathway ⬇️

A gastrin precursor, gastrin-gly, upregulates VEGF expression in colonic epithelial cells through an HIF-1-independent mechanism

Characterization of immortalized human dermal microvascular endothelial cells (HMEC-1) for the study of HDL functionality

Characterization of pancreastatin receptor and signaling in rat HTC hepatoma cells

Ecto-F1-ATPase/P2Y pathways in metabolic and vascular functions of high density lipoproteins.

Ectopic adenine nucleotide translocase activity controls extracellular ADP levels and regulates the F1-ATPase-mediated HDL endocytosis pathway on hepatocytes.

Homocysteine thiolactone inhibits insulin signaling, and glutathione has a protective effect

Homocysteine thiolactone inhibits insulin-stimulated DNA and protein synthesis: possible role of mitogen-activated protein kinase (MAPK), glycogen synthase kinase-3 (GSK-3) and p70 S6K phosphorylation

Human leptin promotes survival of human circulating blood monocytes prone to apoptosis by activation of p42/44 MAPK pathway

Identification of the F1-ATPase at the cell surface of colonic epithelial cells: role in mediating cell proliferation.

Insulin activates Gαil,2 protein in rat hepatoma (HTC) cell membranes

Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells.

Liraglutide improves hepatic steatosis and metabolic dysfunctions in a 3-week dietary mouse model of nonalcoholic steatohepatitis

Paclitaxel induces lymphatic endothelial cells autophagy to promote metastasis

Pancreastatin, a chromogranin A-derived peptide, inhibits DNA and protein synthesis by producing nitric oxide in HTC rat hepatoma cells.

Pancreastatin. Biological effects and mechanisms of action

Phosphatidylinositol 3-kinase-dependent transcriptional silencing of the translational repressor 4E-BP1.

Progastrin a new pro-angiogenic factor in colorectal cancer

Reprint of: Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin.

Role of Sam68 as an adaptor protein in signal transduction

Role of leptin as an immunomodulator of blood mononuclear cells: mechanisms of action

Role of leptin in the activation of immune cells.

Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling

Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling

Sam68 is tyrosine phosphorylated and recruited to signalling in peripheral blood mononuclear cells from HIV infected patients

The expression of Sam68, a protein involved in insulin signal transduction, is enhanced by insulin stimulation.

eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells

p68 Sam is a substrate of the insulin receptor and associates with the SH2 domains of p85 PI3K