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List of works by Susan S Wallace

5-Hydroxypyrimidine deoxynucleoside triphosphates are more efficiently incorporated into DNA by exonuclease-free Klenow fragment than 8-oxopurine deoxynucleoside triphosphates

scientific article

A Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease Complex

scientific article

A Role for the Fifth G-Track in G-Quadruplex Forming Oncogene Promoter Sequences during Oxidative Stress: Do These "Spare Tires" Have an Evolved Function?

scientific article

A new technique for the quantitative assessment of 8-oxoguanine in nuclear DNA as a marker of oxidative stress. Application to dystrophin-deficient DMD skeletal muscles

scientific article published in September 2005

A novel bicistronic vector for overexpressing Mycobacterium tuberculosis proteins in Escherichia coli

scientific article published on 30 December 2008

A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII

scientific article (publication date: 17 July 2002)

A novel method for site specific introduction of single model oxidative DNA lesions into oligodeoxyribonucleotides

scientific article

A novel role for Escherichia coli endonuclease VIII in prevention of spontaneous G-->T transversions.

scientific article

A novel, sensitive, and specific assay for abasic sites, the most commonly produced DNA lesion.

scientific article published in April 1992

A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol

scientific article

Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli

scientific article published on 12 June 2001

Absence of a role for DNA polymerase II in SOS-induced translesion bypass of phi X174.

scientific article

An Escherichia coli endonuclease which acts on x-irradiated DNA

scientific article published on January 1, 1975

Antibodies specific for purine and pyrimidine nucleosides: effect on in vitro priming ability of DNA.

scientific article

Antibodies to nucleic acids. Immunochemical studies on dinucleoside phosphate-protein conjugates

scientific article published on 16 February 1971

Antibodies to oxidative DNA damage: characterization of antibodies to 8-oxopurines

scientific article published in 1997

Apurinic endonuclease activity remains constant during early drosophila development

scientific article published in October 1984

Apurinic endonucleases from Saccharomyces cerevisiae ⬇️

scientific article published on September 1, 1978

Attempted base excision repair of ionizing radiation damage in human lymphoblastoid cells produces lethal and mutagenic double strand breaks

scientific article published in October 2004

Base Excision Repair Variants in Cancer.

scientific article published on 5 May 2017

Base excision repair and cancer

scientific article

Base excision repair by hNTH1 and hOGG1: a two edged sword in the processing of DNA damage in gamma-irradiated human cells

scientific article published on 18 August 2005

Base excision repair processing of radiation-induced clustered DNA lesions.

scientific article

Base excision repair: NMR backbone assignments of Escherichia coli formamidopyrimidine-DNA glycosylase.

scientific article

Base excision repair: a critical player in many games

scientific article

Biological consequences of free radical-damaged DNA bases.

scientific article

Bumps in the road: how replicative DNA polymerases see DNA damage

scientific article

Caught bending the A-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide

scientific article

Characterization of Escherichia coli Endonuclease VIII

scientific article published on 19 December 1997

Characterization of a novel metabolic strategy used by drug-resistant tumor cells

scientific article published in October 2002

Characterization of antibodies to dihydrothymine, a radiolysis product of DNA

scientific article published on 16 May 1989

Characterization of the Escherichia coli X-ray endonuclease, endonuclease III.

scientific article published in August 1983

Chemically altered apurinic sites in phi X174 DNA give increased mutagenesis in SOS-induced E. coli.

scientific article

Clostridium acetobutylicum 8-oxoguanine DNA glycosylase (Ogg) differs from eukaryotic Oggs with respect to opposite base discrimination

scientific article published on 26 June 2008

Contribution of DNA unwrapping from histone octamers to the repair of oxidatively damaged DNA in nucleosomes

scientific article published on 17 September 2013

Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair

scientific article published on 01 April 2020

Crystal Structure of a Replicative DNA Polymerase Bound to the Oxidized Guanine Lesion Guanidinohydantoin ,

scientific article

Crystal Structures of Two Archaeal 8-Oxoguanine DNA Glycosylases Provide Structural Insight into Guanine/8-Oxoguanine Distinction

scientific article

Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site

scientific article published on April 2004

DNA glycosylases search for and remove oxidized DNA bases

scientific article published on 07 October 2013

DNA polymerases provide a canon of strategies for translesion synthesis past oxidatively generated lesions

scientific article

Decline of nuclear and mitochondrial oxidative base excision repair activity in late passage human diploid fibroblasts

scientific article published in June 2003

Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.

scientific article published on 17 October 2016

Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase

scientific article

Detection and repair of DNA base damages produced by ionizing radiation ⬇️

scientific article published on January 1, 1983

Effect of X-Irradiation on Gene Function in Bacteriophage T4

scientific article published on August 1, 1970

Effects of base damages on DNA replication

scientific article published on 01 January 1991

Endonucleolytic incision of x-irradiated deoxyribonucleic acid by extracts of Escherichia coli

scientific article

Engineering functional changes in Escherichia coli endonuclease III based on phylogenetic and structural analyses

scientific article published on 11 August 2005

Enzymatic Processing of Uracil Glycol, a Major Oxidative Product of DNA Cytosine

scientific article published on 17 April 1998

Enzymatic processing of radiation-induced free radical damage in DNA

scientific article published in November 1998

Escherichia coli endonuclease VIII: cloning, sequencing, and overexpression of the nei structural gene and characterization of nei and nei nth mutants

scientific article published on June 1997

Estimation of DNA Sequence Context-dependent Mutation Rates Using Primate Genomic Sequences

scientific article published on 4 August 2007

Expression and purification of active mouse and human NEIL3 proteins.

scientific article

Expression of cloned bacteriophage T4 uvsW and uvsY genes in rec+ and rec- Escherichia coli ⬇️

scientific article published on September 1, 1983

Expression of the oxidative base excision repair enzymes is not induced in TK6 human lymphoblastoid cells after low doses of ionizing radiation.

scientific article published on April 2004

Fabs specific for 8-oxoguanine: control of DNA binding

scientific article

Fluorescence detection of 8-oxoguanine in nuclear and mitochondrial DNA of cultured cells using a recombinant Fab and confocal scanning laser microscopy.

scientific article

Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing

scientific article

Germ-line variant of human NTH1 DNA glycosylase induces genomic instability and cellular transformation

scientific article published on 12 August 2013

Host- and phage-mediated repair of radiation damage in bacteriophage T4.

scientific article published on December 1972

Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides

scientific article

Human endonuclease VIII-like (NEIL) proteins in the giant DNA Mimivirus

scientific article

In search of a mutational hotspot ⬇️

scientific article published on July 21, 1998

In vitro selection of sequence contexts which enhance bypass of abasic sites and tetrahydrofuran by T4 DNA polymerase holoenzyme.

scientific article published on March 1999

Incorporation of thymine-containing DNA precursors in plasmolysed cells infected by the T4 non-lethal recombination defective mutants.

scientific article published on January 1983

Incorporation of thymine-containing DNA precursors in wild-type and mutant T4-infected plasmolysed cells

scientific article published in 1983

Influence of .alpha.-Deoxyadenosine on the Stability and Structure of DNA. Thermodynamic and Molecular Mechanics Studies

scientific article published on 30 May 1995

Inhibition of oxidative DNA repair in cadmium-adapted alveolar epithelial cells and the potential involvement of metallothionein

scientific article published in March 2001

Initiation of base excision repair of oxidative lesions in nucleosomes by the human, bifunctional DNA glycosylase NTH1.

scientific article published on 8 October 2007

Insights into the glycosylase search for damage from single-molecule fluorescence microscopy

scientific article

Isolation and characterization of endonuclease VIII from Escherichia coli.

scientific article

Kinetics of Mismatch Formation opposite Lesions by the Replicative DNA Polymerase from Bacteriophage RB69

scientific article

Kinetics of error generation in homologous B-family DNA polymerases.

scientific article

Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts.

scientific article

Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro.

scientific article published on January 1994

Mechanism of action of Escherichia coli endonuclease III

scientific article published in December 1987

Mechanism of action of Micrococcus luteus .gamma.-endonuclease

scientific article published in October 1987

Methylperoxyl radicals as intermediates in the damage to DNA irradiated in aqueous dimethyl sulfoxide with gamma rays

scientific article published in October 1996

Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIII

scientific article

Multiprobe RNase protection assay analysis of mRNA levels for the Escherichia coli oxidative DNA glycosylase genes under conditions of oxidative stress

scientific article

NEIL3 Repairs Telomere Damage during S Phase to Secure Chromosome Segregation at Mitosis

scientific article published on August 2017

Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context

scientific article

Neil3, the final frontier for the DNA glycosylases that recognize oxidative damage.

scientific article published on 26 December 2012

New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-

scientific article published on July 1994

Non-specific DNA binding interferes with the efficient excision of oxidative lesions from chromatin by the human DNA glycosylase, NEIL1.

scientific article

Nucleosome disruption by DNA ligase III-XRCC1 promotes efficient base excision repair

scientific article

Nucleosomes suppress the formation of double-strand DNA breaks during attempted base excision repair of clustered oxidative damages

scientific article

Overproduction, crystallization and preliminary crystallographic analysis of a novel human DNA-repair enzyme that recognizes oxidative DNA damage

scientific article

Oxidative DNA Glycosylases: Recipes from Cloning to Characterization

scientific article published in 2006

Oxidative damage in DNA. Lack of mutagenicity by thymine glycol lesions.

scientific article

Personal reflections of a woman scientist growing up in a man’s world

scientific article published in May 2013

Phenotypic differences among the alleles of the T4 recombination defective mutants

scientific article published in September 1980

Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases.

scientific article published on 12 February 2009

Probing the activity of NTHL1 orthologs by targeting conserved amino acid residues

scientific article published on 6 March 2017

Processing of DNA base damage by DNA polymerases. Dihydrothymine and beta-ureidoisobutyric acid as models for instructive and noninstructive lesions

scientific article (publication date: 25 January 1991)

Processing of model single-strand breaks in phi X-174 RF transfecting DNA by Escherichia coli.

scientific article

Processing of ring saturation and fragmentation products of DNA thymine in Escherichia coli.

scientific article published in January 1989

Properties of a monoclonal antibody for the detection of abasic sites, a common DNA lesion

scientific article published in May 1992

Properties of the nonlethal recombinational repair deficient mutants of bacteriophage T4

scientific article published in February 1980

Properties of the nonlethal recombinational repair x and y mutants of bacteriophage T4. II. DNA synthesis.

scientific article published on October 1977

Pyrimidine ring fragmentation products. Effects of lesion structure and sequence context on mutagenesis.

scientific article

Radiation-induced DNA base damage detected in individual aerobic and hypoxic cells with endonuclease III and formamidopyrimidine-glycosylase

scientific article published in May 1999

Radiation-induced and transposon-induced chromosome damage in Drosophila: translocations and transmission distortion

scientific article published in September 1988

Rapid determination of the active fraction of DNA repair glycosylases: a novel fluorescence assay for trapped intermediates.

scientific article published on 8 February 2007

Recombinant Phabs reactive with 7,8-dihydro-8-oxoguanine, a major oxidative DNA lesion

scientific article published on 01 February 1996

Repair of psoralen plus near ultraviolet light damage in bacteriophage T4 ⬇️

scientific article published on September 1, 1979

Repair-defective mutants of Alteromonas espejiana, the host for bacteriophage PM2.

scientific article

Reversion of bacteriophage T4rIImutants by high levels of pyrimidine deoxyribonucleosides

scientific article published in June 1982

Rules of engagement for base excision repair in chromatin

scientific article

SOS processing of unique oxidative DNA damages in Escherichia coli

scientific article published in May 1989

Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria

scientific article

Selective inhibition of in vitro DNA synthesis dependent on phiX174 compared with fd DNA. I. Protein requirements for selective inhibition ⬇️

scientific article published on April 25, 1977

Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNA

scientific article

Single molecule glycosylase studies with engineered 8-oxoguanine DNA damage sites show functional defects of a MUTYH polyposis variant

Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts.

scientific article

Solution-state NMR investigation of DNA binding interactions in Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg): a dynamic description of the DNA/protein interface.

scientific article published in March 2005

Spectroscopic studies of zinc(II)- and cobalt(II)-associated Escherichia coli formamidopyrimidine-DNA glycosylase: extended X-ray absorption fine structure evidence for a metal-binding domain

scientific article published in October 2000

Structural Characterization of Clostridium acetobutylicum 8-Oxoguanine DNA Glycosylase in Its Apo Form and in Complex with 8-Oxodeoxyguanosine

scientific article

Structural Characterization of Viral Ortholog of Human DNA Glycosylase NEIL1 Bound to Thymine Glycol or 5-Hydroxyuracil-containing DNA

scientific article

Structural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNA

scientific article

Structural Characterization of a Viral NEIL1 Ortholog Unliganded and Bound to Abasic Site-containing DNA

scientific article

Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family

scientific article

Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine

scientific article

Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase

scientific article

Structural investigation of a viral ortholog of human NEIL2/3 DNA glycosylases

scientific article

Studies on Escherichia coli X-Ray Endonuclease Specificity: Roles of Hydroxyl and Reducing Radicals in the Production of DNA Lesions

scientific article published on February 1, 1977

Synthesis of dihydrothymidine and thymidine glycol 5'-triphosphates and their ability to serve as substrates for Escherichia coli DNA polymerase I.

scientific article

The C-terminal Lysine of Ogg2 DNA Glycosylases is a Major Molecular Determinant for Guanine/8-Oxoguanine Distinction

scientific article

The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damage

scientific article

The Human Ligase IIIα-XRCC1 Protein Complex Performs DNA Nick Repair after Transient Unwrapping of Nucleosomal DNA.

scientific article

The Miscoding Potential of 5-Hydroxycytosine Arises Due to Template Instability in the Replicative Polymerase Active Site

scientific article

The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures

scientific article published on 27 June 2015

The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures

scientific article published on 26 March 2015

The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation.

scientific article published on 8 September 2017

The Production of Alkali-labile Lesions in X-irradiated PM2 DNA ⬇️

scientific article published on November 1, 1978

The Sequence Context-Dependent Mispairing of 5-Hydroxycytosine and 5-Hydroxyuridine in Vitro

scientific article published in July 1994

The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype

scientific article

The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity

scientific article

The effect of exogenous deoxyribonucleosides on thymidine incorporation in T4-infected cells ⬇️

scientific article published on March 1, 1978

The enigma of endonuclease VIII.

scientific article

The genes encoding endonuclease VIII and endonuclease III in Escherichia coli are transcribed as the terminal genes in operons.

scientific article

The genes encoding formamidopyrimidine and MutY DNA glycosylases in Escherichia coli are transcribed as part of complex operons.

scientific article

The interaction between X-rays and transposon mobility in Drosophila: hybrid sterility and chromosome loss

scientific article published in November 1989

The lyase activity of bifunctional DNA glycosylases and the 3'-diesterase activity of APE1 contribute to the repair of oxidized bases in nucleosomes

The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

scientific journal article

The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts

scientific journal article

The phosphodiester bond 3' to a deoxyuridine residue is crucial for substrate binding for uracil DNA N-glycosylase.

scientific article

The relationship between radiation-induced and transposon-induced genetic damage during Drosophila oogenesis

scientific article published in August 1986

The relationship between radiation-induced and transposon-induced genetic damage during Drosophila spermatogenesis

scientific article published in August 1987

Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.

scientific article published on November 1985

Thymine ring saturation and fragmentation products: lesion bypass, misinsertion and implications for mutagenesis.

scientific article

Two glycosylase families diffusively scan DNA using a wedge residue to probe for and identify oxidatively damaged bases

scientific article

Unhooking of an interstrand cross-link at DNA fork structures by the DNA glycosylase NEIL3

scientific article published on 20 November 2019

Uracil DNA N-glycosylase distributively interacts with duplex polynucleotides containing repeating units of either TGGCCAAGCU or TGGCCAAGCTTGGCCAAGCU.

scientific article

Uracil Glycol Deoxynucleoside Triphosphate Is a Better Substrate for DNA Polymerase I Klenow Fragment Than Thymine Glycol Deoxynucleoside Triphosphate†

scientific article published in January 1998

Using shifts in amino acid frequency and substitution rate to identify latent structural characters in base-excision repair enzymes

scientific article

UvrABC nuclease complex repairs thymine glycol, an oxidative DNA base damage

scientific article published in March 1990

Variant base excision repair proteins: contributors to genomic instability

scientific article

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