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List of works by Frederic A Meunier

A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1.

scientific article

A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation

scientific article

A role for SNAREs in neuronal survival?

scientific article published on 02 April 2014

A role for tropomyosins in activity-dependent bulk endocytosis?

scientific article published on 22 May 2017

Abrogating Munc18-1-SNARE complex interaction has limited impact on exocytosis in PC12 cells

scientific article published on 29 May 2009

Actin Remodeling in Regulated Exocytosis: Toward a Mesoscopic View

scientific article published on 11 May 2018

Actin- and dynamin-dependent maturation of bulk endocytosis restores neurotransmission following synaptic depletion

scientific article (publication date: 2012)

Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking

scientific article published on 24 February 2015

Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies.

scientific article published on 15 December 2017

An acto-myosin II constricting ring initiates the fission of activity-dependent bulk endosomes in neurosecretory cells.

scientific article published in January 2015

An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cells

scientific article published on 08 September 2020

Arachidonic acid potentiates exocytosis and allows neuronal SNARE complex to interact with Munc18a

scientific article published on 23 December 2006

Botulinum neurotoxin type-A enters a non-recycling pool of synaptic vesicles.

scientific article

Botulinum neurotoxins: from paralysis to recovery of functional neuromuscular transmission

scientific article

Brevenal inhibits pacific ciguatoxin-1B-induced neurosecretion from bovine chromaffin cells

scientific article

Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis

scientific article published on 9 October 2013

Bulk endocytosis at neuronal synapses

scientific article published on 18 March 2014

Ca(2+) and Na(+) contribute to the swelling of differentiated neuroblastoma cells induced by equinatoxin-II.

scientific article

Ca2+-regulated pool of phosphatidylinositol-3-phosphate produced by phosphatidylinositol 3-kinase C2alpha on neurosecretory vesicles

scientific article

Cancer survivorship: A positive side-effect of more successful cancer treatment

scientific article

Captivating New Roles of F-Actin Cortex in Exocytosis and Bulk Endocytosis in Neurosecretory Cells.

scientific article

Ciguatoxin-induced catecholamine secretion in bovine chromaffin cells: mechanism of action and reversible inhibition by brevenal

scientific article published on 11 August 2009

Comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system

scientific article

Control of autophagosome axonal retrograde flux by presynaptic activity unveiled using botulinum neurotoxin type a

scientific article published on April 2015

Decatenation checkpoint-defective melanomas are dependent on PI3K for survival

scientific article

Dynamic control of neuroexocytosis by phosphoinositides in health and disease.

scientific article published on 10 August 2010

Dynamics of motor nerve terminal remodeling unveiled using SNARE-cleaving botulinum toxins: the extent and duration are dictated by the sites of SNAP-25 truncation

article

Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism

scientific article

ENA/VASP proteins regulate exocytosis by mediating myosin VI-dependent recruitment of secretory granules to the cortical actin network

scientific article published on 04 August 2017

Effects of trachynilysin, a protein isolated from stonefish (Synanceia trachynis) venom, on frog atrial heart muscle.

scientific article

Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.

scientific article

Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB

scientific article

Frontotemporal dementia mutant Tau promotes aberrant Fyn nanoclustering in hippocampal dendritic spines.

scientific article published on 25 June 2019

Functional recycling of C2 domains throughout evolution: a comparative study of synaptotagmin, protein kinase C and phospholipase C by sequence, structural and modelling approaches

scientific article

Functional repair of motor endplates after botulinum neurotoxin type A poisoning: biphasic switch of synaptic activity between nerve sprouts and their parent terminals.

scientific article

G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channel Activation by the p75 Neurotrophin Receptor Is Required for Amyloid β Toxicity

scientific article

Getting muscles moving again after botulinum toxin: novel therapeutic challenges

scientific article

Glycerotoxin from Glycera convoluta stimulates neurosecretion by up-regulating N-type Ca2+ channel activity

scientific article

Glycerotoxin stimulates neurotransmitter release from N-type Ca2+ channel expressing neurons

scientific article published on 02 June 2006

High affinity interaction of syntaxin and SNAP-25 on the plasma membrane is abolished by botulinum toxin E.

scientific article published on 9 October 2003

High throughput analysis of endogenous glutamate release using a fluorescence plate reader

scientific article

Identification of Secretory Granule Phosphatidylinositol 4,5-Bisphosphate-interacting Proteins Using an Affinity Pulldown Strategy

In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters

scientific article

Increased polyubiquitination and proteasomal degradation of a Munc18-1 disease-linked mutant causes temperature-sensitive defect in exocytosis

scientific article

Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death

scientific article (publication date: 2013)

Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella

scientific article

Ionic mechanisms involved in the nodal swelling of myelinated axons caused by marine toxins

scientific article published on 01 January 2002

Latrophilin, Neurexin, and Their Signaling-deficient Mutants Facilitate α-Latrotoxin Insertion into Membranes but Are Not Involved in Pore Formation

scientific article published in Journal of Biological Chemistry

Lipid dynamics in exocytosis.

scientific article

Mapping organelle motion reveals a vesicular conveyor belt spatially replenishing secretory vesicles in stimulated chromaffin cells

scientific article published on 29 January 2014

Marine toxins potently affecting neurotransmitter release

scientific article published on January 2009

Munc18-1 as a key regulator of neurosecretion

scientific article published on October 2010

Munc18-1 domain-1 controls vesicle docking and secretion by interacting with syntaxin-1 and chaperoning it to the plasma membrane

scientific article

Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation

scientific article published on 05 September 2016

Munc18a: Munc-y business in mediating exocytosis

scientific article published on 30 November 2006

Myosin VI small insert isoform maintains exocytosis by tethering secretory granules to the cortical actin

scientific article

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

scientific article published on 20 October 2020

Nitric Oxide and Peroxynitrite Affect Differently Acetylcholine Release, Choline Acetyltransferase Activity, Synthesis, and Compartmentation of Newly Formed Acetylcholine in Torpedo marmorata Synaptosomes

scientific article published on 01 August 1997

Noninvasive measurement of intracellular viscoelastic properties

Norepinephrine exocytosis stimulated by alpha-latrotoxin requires both external and stored Ca2+ and is mediated by latrophilin, G proteins and phospholipase C

scientific journal article

PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model

scientific article

PIKfyve negatively regulates exocytosis in neurosecretory cells

scientific article

Phosphatidylinositol 3-kinase C2alpha is essential for ATP-dependent priming of neurosecretory granule exocytosis

scientific article published on 29 July 2005

Phosphatidylinositol(4,5)bisphosphate coordinates actin-mediated mobilization and translocation of secretory vesicles to the plasma membrane of chromaffin cells.

scientific article

Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion

scientific article

Phosphoinositide regulation of neuroexocytosis: adding to the complexity

scientific article published on July 2006

Phosphoinositides in neuroexocytosis and neuronal diseases

scientific article published on January 2012

Phospholipases in neuronal function: A role in learning and memory?

scientific article published on 19 November 2019

Profiling of Free Fatty Acids Using Stable Isotope Tagging Uncovers a Role for Saturated Fatty Acids in Neuroexocytosis

scientific article published on 20 October 2015

Publisher Correction: In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters.

scientific article

Recreation of neuronal Kv1 channel oligomers by expression in mammalian cells using Semliki Forest virus

scientific article published in December 1999

Regioselective approach to phosphatidylinositol 3,5-bisphosphates: syntheses of the native phospholipid and biotinylated short-chain derivative

scientific article published on June 2010

Rescue of Munc18-1 and -2 double knockdown reveals the essential functions of interaction between Munc18 and closed syntaxin in PC12 cells

scientific article published on 07 October 2009

Reversed Mode Na+-Ca2+ Exchange Activated by Ciguatoxin (CTX-1b) Enhances Acetylcholine Release from Torpedo Cholinergic Synaptosomesa

scientific article published on 01 April 1996

SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity

Secretagogue stimulation of neurosecretory cells elicits filopodial extensions uncovering new functional release sites

scientific article published in December 2013

Selective Depletion of Clear Synaptic Vesicles and Enhanced Quantal Transmitter Release at Frog Motor Nerve Endings Produced by Trachynilysin, a Protein Toxin Isolated from Stonefish (Synanceia trachynis) Venom

scientific article published on 01 October 1996

Selective depolarization of the muscle membrane in frog nerve-muscle preparations by a chromatographically purified extract of the dinoflagellate Ostreopsis lenticularis.

scientific article

Small molecules demonstrate the role of dynamin as a bi-directional regulator of the exocytosis fusion pore and vesicle release

scientific article published on 5 May 2015

Sodium-dependent increase in quantal secretion induced by brevetoxin-3 in Ca2+-free medium is associated with depletion of synaptic vesicles and swelling of motor nerve terminals in situ

scientific article published in June 1997

Subdiffractional tracking of internalized molecules reveals heterogeneous motion states of synaptic vesicles

scientific article published on 24 October 2016

Sustained synaptic-vesicle recycling by bulk endocytosis contributes to the maintenance of high-rate neurotransmitter release stimulated by glycerotoxin

scientific article

Synaptotagmin interaction with the syntaxin/SNAP-25 dimer is mediated by an evolutionarily conserved motif and is sensitive to inositol hexakisphosphate

scientific article

Synthetic self-assembling clostridial chimera for modulation of sensory functions

scientific article published on 20 September 2013

Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors

scientific article

The 18th International Symposia on Chromaffin Cell Biology

scientific article published on 18 April 2016

The Janus faces of botulinum neurotoxin: sensational medicine and deadly biological weapon

scientific article published on May 2007

The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming

scientific article published on 19 September 2016

The Munc18-1 domain 3a loop is essential for neuroexocytosis but not for syntaxin-1A transport to the plasma membrane

scientific article published in June 2013

The SAC1 domain in synaptojanin is required for autophagosome maturation at presynaptic terminals

scientific article published on 22 March 2017

The cortical acto-Myosin network: from diffusion barrier to functional gateway in the transport of neurosecretory vesicles to the plasma membrane

scientific article published on 21 October 2013

The peripheral nerve and the neuromuscular junction are affected in the tenascin-C-deficient mouse

scientific journal article

Trachynilysin mediates SNARE-dependent release of catecholamines from chromaffin cells via external and stored Ca2+.

scientific article

Trapping of Syntaxin1a in Presynaptic Nanoclusters by a Clinically Relevant General Anesthetic

scientific article published in January 2018

Vesicle exocytosis stimulated by α-latrotoxin is mediated by latrophilin and requires both external and stored Ca2+

scientific article published on July 15, 1998

Visualizing endocytic recycling and trafficking in live neurons by subdiffractional tracking of internalized molecules

scientific article published on 30 November 2017

p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model

scientific article published on 30 July 2019

p75 neurotrophin receptor mediates neuronal cell death by activating GIRK channels through phosphatidylinositol 4,5-bisphosphate.

scientific article published in January 2008