List of works by Piero Sestili

1,3 dideazaadenosine is a mitogen for cultured mammalian cells.

scientific article published on April 1986

AG8 cells, which are highly resistant to hydrogen peroxide, display collateral sensitivity to the combination of hydrogen peroxide and L-histidine.

scientific article

Adriamycin does not affect the repair of X-ray induced DNA single strand breaks

scientific article published on 01 June 1985

Analogues of benzamide as poly(ADP-ribose)transferase inhibitors: a study on structure activity relationships

scientific article published on 01 July 1988

Antileukemic activity of sulforaphane in primary blasts from patients affected by myelo- and lympho-proliferative disorders and in hypoxic conditions

scientific article

Antioxidant Effect of Ocimum basilicum Essential Oil and Its Effect on Cooking Qualities of Supplemented Chicken Nuggets

scientific article published in 2022

Apoptosis and necrosis following exposure of U937 cells to increasing concentrations of hydrogen peroxide: the effect of the poly(ADP-ribose)polymerase inhibitor 3-aminobenzamide

scientific article published on 01 December 1999

Apoptosis of human lymphocytes in the absence or presence of internucleosomal DNA cleavage

scientific article published on 01 December 1996

Arachidonic acid induces calcium-dependent mitochondrial formation of species promoting strand scission of genomic DNA

scientific article published on 01 June 2000

Calcium chelator Quin 2 prevents hydrogen-peroxide-induced DNA breakage and cytotoxicity

scientific article published on 01 June 1989

Cellular and molecular pharmacology of 4'-epidoxorubicin in HeLa cells. Comparison with its parent drug, doxorubicin

scientific article published on 01 January 1989

Characterization of the Biological Activity of the Ethanolic Extract from the Roots of <i>Cannabis sativa</i> L. Grown in Aeroponics

scientific article published on 27 April 2022

Chilling followed by incubation at 37 degrees C causes a reduction in NAD+ levels which can be prevented by the poly(ADP-ribose)transferase inhibitor 3-aminobenzamide

scientific article published on 01 August 1986

Comparative effects of doxorubicin and 4?-epi-doxorubicin on nucleic acid metabolism and cytotoxicity in a human tumor cell line ⬇️

scientific article published on January 1, 1990

Creatine Prevents the Structural and Functional Damage to Mitochondria in Myogenic, Oxidatively Stressed C2C12 Cells and Restores Their Differentiation Capacity

scientific article published on 17 August 2016

Creatine affects in vitro electrophysiological maturation of neuroblasts and protects them from oxidative stress

scientific article

Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress

scientific article published on 27 July 2006

Creatine as an antioxidant.

scientific article published on 15 March 2011

Creatine supplementation affords cytoprotection in oxidatively injured cultured mammalian cells via direct antioxidant activity

scientific article published on 2 November 2005

Creatine supplementation prevents the inhibition of myogenic differentiation in oxidatively injured C2C12 murine myoblasts

scientific article published in September 2009

Cytoprotective effect of preparations from various parts of Punica granatum L. fruits in oxidatively injured mammalian cells in comparison with their antioxidant capacity in cell free systems.

scientific article published on 20 February 2007

Cytotoxic and Antitumor Activity of Sulforaphane: The Role of Reactive Oxygen Species

scientific article (publication date: 2015)

Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells

scientific article published in March 2002

Delayed formation of hydrogen peroxide mediates the lethal response evoked by peroxynitrite in U937 cells.

scientific article published in April 2002

Deuterium Incorporation Protects Cells from Oxidative Damage

scientific article published on 18 July 2019

Development and characterization of hydrogen peroxide-resistant Chinese hamster ovary (CHO) cell variants--II. Relationships between non-protein sulfhydryl levels and the induction/stability of the oxidant-resistant phenotype.

scientific article

Development and characterization of hydrogen peroxide-resistant Chinese hamster ovary cell variants--I. Relationship between catalase activity and the induction/stability of the oxidant-resistant phenotype.

scientific article

Dietary Habits and Psychological States during COVID-19 Home Isolation in Italian College Students: The Role of Physical Exercise

scientific article published on 28 November 2020

Dietary supplementation with α-tocopherol reduces neuroinflammation and neuronal degeneration in the rat brain after kainic acid-induced status epilepticus

scientific article

Differential effect of creatine on oxidatively-injured mitochondrial and nuclear DNA.

scientific article published on 5 October 2007

Direct excision of 50 kb pair DNA fragments from megabase-sized fragments produced during apoptotic cleavage of genomic DNA

scientific article published on 01 November 1996

Effects of Creatine in Skeletal Muscle Cells and in Myoblasts Differentiating Under Normal or Oxidatively Stressing Conditions

scientific article published on 21 July 2015

Effects of a 300 mT static magnetic field on human umbilical vein endothelial cells

scientific article published on 01 December 2010

Effects of a commercially available branched-chain amino acid-alanine-carbohydrate-based sports supplement on perceived exertion and performance in high intensity endurance cycling tests

scientific article published on 20 January 2020

Effects of sex hormones on inflammatory response in male and female vascular endothelial cells.

scientific article published on 20 June 2014

Electric and/or magnetic field effects on DNA structure and function in cultured human cells

scientific article published on 01 May 1992

Ellagitannins in Cancer Chemoprevention and Therapy

scientific article

Endogenous and exogenous nitric oxide enhance the DNA strand scission induced by tert-butylhydroperoxide in PC12 cells via peroxynitrite-dependent and independent mechanisms, respectively.

scientific article published in January 2000

Evidence for separate mechanisms of cytotoxicity in mammalian cells treated with hydrogen peroxide in the absence or presence of L-histidine

article

Exploiting RNA as a new biomolecular target for synthetic polyamines

scientific article published on 19 April 2013

Extracellular Vesicles Released by Oxidatively Injured or Intact C2C12 Myotubes Promote Distinct Responses Converging toward Myogenesis

scientific article published on 22 November 2017

Gene expression profile in cultured human umbilical vein endothelial cells exposed to a 300 mT static magnetic field.

scientific article

Glycemic and Insulinemic Responses of Vegetables and Beans Powders Supplemented Chapattis in Healthy Humans: A Randomized, Crossover Trial

scientific article published on 13 October 2019

High-intensity Interval Training Promotes the Shift to a Health-Supporting Dietary Pattern in Young Adults

scientific article published on 21 March 2020

Hydrogen peroxide cytotoxicity under conditions of normal or reduced catalase activity in H2O2-sensitive and -resistant Chinese hamster ovary (CHO) cell variants.

scientific article published on September 1994

Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2.

scientific article

Identification of 4 ataxia telangiectasia cell lines hypersensitive to γ-irradiation but not to hydrogen peroxide

scientific article published on 01 September 1989

Induction of DNA double strand breaks in cultured mammalian cells exposed to hydrogen peroxide and histidine

scientific article published on 01 February 1991

Inhibition of AMPK signalling by doxorubicin: at the crossroads of the cardiac responses to energetic, oxidative, and genotoxic stress.

scientific article

Inhibition of Chinese hamster ovary cell DNA synthesis by hydrogen peroxide

scientific article published in January 1990

Inhibition of nucleic acids and protein synthesis by deazaadenosine derivatives: a study on structure-activity relationships

scientific article published in December 1985

L-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity: relationships between DNA single/double strand breakage and cell killing

scientific article published on 01 February 1994

Lipoxygenase-mediated pro-radical effect of melatonin via stimulation of arachidonic acid metabolism.

scientific article

Low levels of hydrogen peroxide and L-histidine induce DNA double-strand breakage and apoptosis.

scientific article published on December 1996

Maternal Creatine Supplementation Positively Affects Male Rat Hippocampal Synaptic Plasticity in Adult Offspring

scientific article published on 27 August 2019

Maternal creatine supplementation affects the morpho-functional development of hippocampal neurons in rat offspring.

scientific article published on 17 November 2015

Mitochondrial respiratory chain deficiency leads to overexpression of antioxidant enzymes

scientific article published on 01 December 1997

Molecular damage and induction of proinflammatory cytokines in human endothelial cells exposed to Shiga toxin 1, Shiga toxin 2, and alpha-sarcin

scientific article published on 12 February 2007

Muscle and Bone Health in Postmenopausal Women: Role of Protein and Vitamin D Supplementation Combined with Exercise Training

article

Muscular viscoelastic characteristics of athletes participating in the European Master Indoor Athletics Championship

scientific article

Mutual Interactions among Exercise, Sport Supplements and Microbiota

scientific article published on 20 December 2019

New insights into the trophic and cytoprotective effects of creatine in in vitro and in vivo models of cell maturation

scientific article published on 02 January 2016

Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide

scientific article

Overview of the Anticancer Potential of the "King of Spices" <i>Piper nigrum</i> and Its Main Constituent Piperine

scientific article published on 26 November 2020

Peroxynitrite stimulates the activity of cytosolic phospholipase A2 in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death

scientific article published in December 2002

Pomegranate peel and fruit extracts: a review of potential anti-inflammatory and anti-infective effects.

scientific article published on 20 July 2012

Pomegranate peel and peel extracts: chemistry and food features.

scientific article

Post-Activation Potentiation Increases Recruitment of Fast Twitch Fibers: A Potential Practical Application in Runners

Products of the phospholipase A(2) pathway mediate the dihydrorhodamine fluorescence response evoked by endogenous and exogenous peroxynitrite in PC12 cells

scientific article published on 01 October 2000

Protective Role of Italian Juglans Regia L. Nut Ethanolic Extract in Human Keratinocytes under Oxidative and Inflammatory Stress.

scientific article published on 12 January 2018

Protective effect of creatine against RNA damage.

scientific article published on 23 July 2009

Quercetin prevents DNA single strand breakage and cytotoxicity caused by tert-butylhydroperoxide: free radical scavenging versus iron chelating mechanism

scientific article published on 01 July 1998

RNA as a new target for toxic and protective agents

scientific article published on 18 September 2008

Randomly distributed DNA single strand breaks are not lethal for mammalian cells

scientific article published on 01 December 1988

Reactive oxygen species in skeletal muscle signaling.

scientific article published on 5 December 2011

Regulatory role of extracellular medium components in metal induced cyto- and geno-toxicity

scientific article published on 01 December 1986

Repositioning Chromones for Early Anti-inflammatory Treatment of COVID-19

scientific article published on 05 June 2020

Rotenone and pyruvate prevent the tert-butylhydroperoxide-induced necrosis of U937 cells and allow them to proliferate

scientific article

Shiga toxin 1 and ricin inhibit the repair of H2O2-induced DNA single strand breaks in cultured mammalian cells

scientific article published in February 2005

Shiga toxin 1, as DNA repair inhibitor, synergistically potentiates the activity of the anticancer drug, mafosfamide, on raji cells

scientific article published on 21 February 2013

Structural requirements for inhibitors of poly(ADP-ribose) Polymerase

scientific article published on 01 January 1990

Sulforaphane induces DNA single strand breaks in cultured human cells.

scientific article

Sulforaphane potentiates RNA damage induced by different xenobiotics

scientific article

The Combination of Physical Exercise with Muscle-Directed Antioxidants to Counteract Sarcopenia: A Biomedical Rationale for Pleiotropic Treatment with Creatine and Coenzyme Q10.

scientific article

The Fast-Halo Assay for the Detection of DNA Damage.

scientific article published in January 2017

The L-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity is a general response in cultured mammalian cell lines and is always associated with the formation of DNA double strand breaks.

scientific article

The antioxidant butylated hydroxytoluene induces apoptosis in human U937 cells: the role of hydrogen peroxide and altered redox state

scientific article published on 01 August 1999

The effect of temperature or anoxia on Escherichia coli killing induced by hydrogen peroxide

scientific article published on 01 April 1987

The expression analysis of mouse interleukin-6 splice variants argued against their biological relevance.

scientific article published in January 2012

The fast halo assay: an improved method to quantify genomic DNA strand breakage at the single-cell level

scientific article

The fast-halo assay for the assessment of DNA damage at the single-cell level

scientific article published in January 2009

The induction/loss of the oxidant-resistant phenotype of Chinese hamster ovary (CHO) cell variants does not correlate with sensitivity to DNA single strand breakage by hydrogen peroxide

scientific article published on 01 November 1994

The role of extracellular medium components and specific amino acids in the cytotoxic response of Escherichia coli and Chinese hamster ovary cells to hydrogen peroxide.

scientific article

Time- and Kellgren⁻Lawrence Grade-Dependent Changes in Intra-Articularly Transplanted Stromal Vascular Fraction in Osteoarthritic Patients.

scientific article published on 3 April 2019

Withania somnifera Induces Cytotoxic and Cytostatic Effects on Human T Leukemia Cells

scientific article published on 12 May 2016

tert-Butylhydroperoxide induces peroxynitrite-dependent mitochondrial permeability transition leading PC12 cells to necrosis

scientific article

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