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List of works by Carol E. Schrader

A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta

scientific article

AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].

scientific article published on 29 July 2011

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.

scientific article

ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.

scientific article

Apurinic/apyrimidinic endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge.

scientific article

Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells.

scientific article

Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats

scientific article published on 24 June 2009

DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations

scientific article published on 29 September 2013

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions

scientific journal article

Dendritic cells support production of IgA and other non-IgM isotypes in clonal microculture

article

Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation

scientific article (publication date: 24 June 2014)

IgH chain class switch recombination: mechanism and regulation

scientific article

Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination

scientific article published on 12 August 2015

Inducible DNA breaks in Ig S regions are dependent on AID and UNG

scientific article

Mechanism and regulation of class switch recombination

scientific article

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination

scientific article published on 23 November 2005

Mismatch repair proteins and AID activity are required for the dominant negative function of C-terminally deleted AID in class switching

scientific article published on 27 June 2014

Mlh1 Can Function in Antibody Class Switch Recombination Independently of Msh2 ⬇️

scientific article published on May 12, 2003

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination

scientific article published on November 2003

Nbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells

scientific article published on 11 August 2015

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

scientific journal article

Response to Comment on “IgH Chain Class Switch Recombination: Mechanism and Regulation”

scientific article published on 01 March 2015

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

scientific journal article

The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells

scientific article

The Sμ Tandem Repeat Region Is Critical for Ig Isotype Switching in the Absence of Msh2 ⬇️

scientific article published on October 1, 2003

The role of Apex2 in class-switch recombination of immunoglobulin genes

article

The roles of APE1, APE2, DNA polymerase beta and mismatch repair in creating S region DNA breaks during antibody class switch

scientific article published on March 2009

p53 represses class switch recombination to IgG2a through its antioxidant function

scientific article published on 5 May 2010

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