List of works by Ana R. Santiago

Activation of Adenosine A3 Receptor Inhibits Microglia Reactivity Elicited by Elevated Pressure

scientific article published on 30 September 2020

Activation of Neuropeptide Y Receptors Modulates Retinal Ganglion Cell Physiology and Exerts Neuroprotective Actions In Vitro

scientific article published on 26 August 2015

Activation of adenosine A3 receptor protects retinal ganglion cells from degeneration induced by ocular hypertension

scientific article published on 27 May 2020

Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure

scientific article

Adenosine A3 receptor activation is neuroprotective against retinal neurodegeneration.

scientific article published on 18 August 2015

Blockade of microglial adenosine A2A receptor impacts inflammatory mechanisms, reduces ARPE-19 cell dysfunction and prevents photoreceptor loss in vitro

scientific article

Blockade of microglial adenosine A2A receptor suppresses elevated pressure-induced inflammation, oxidative stress, and cell death in retinal cells

scientific article published on 22 January 2019

Caffeine administration prevents retinal neuroinflammation and loss of retinal ganglion cells in an animal model of glaucoma.

scientific article

Calcium Dobesilate Is Protective against Inflammation and Oxidative/Nitrosative Stress in the Retina of a Type 1 Diabetic Rat Model.

scientific article published on 10 August 2017

Calcium-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors trigger neuronal nitric-oxide synthase activation to promote nerve cell death in an Src kinase-dependent fashion

scientific article published on 19 September 2012

Caveolin-1-mediated internalization of the vitamin C transporter SVCT2 in microglia triggers an inflammatory phenotype.

scientific article published on 28 March 2017

Contribution of microglia-mediated neuroinflammation to retinal degenerative diseases

scientific article

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice

scientific article

Diabetes changes ionotropic glutamate receptor subunit expression level in the human retina

scientific article published on 6 February 2008

Differential contribution of L-, N-, and P/Q-type calcium channels to [Ca2+]i changes evoked by kainate in hippocampal neurons

scientific article published on 27 March 2008

Effects of 3,4-methylenedioxymethamphetamine administration on retinal physiology in the rat

scientific article

Elevated Pressure Changes the Purinergic System of Microglial Cells.

scientific article published on 24 January 2018

Evaluation of the impact of diabetes on retinal metabolites by NMR spectroscopy.

scientific article published on November 2010

Exosomes derived from microglia exposed to elevated pressure amplify the neuroinflammatory response in retinal cells

scientific article published on 09 July 2020

Glia-Mediated Retinal Neuroinflammation as a Biomarker in Alzheimer's Disease.

scientific article

Having a Coffee Break: The Impact of Caffeine Consumption on Microglia-Mediated Inflammation in Neurodegenerative Diseases.

scientific article published on 31 January 2017

High glucose and diabetes increase the release of [3H]-D-aspartate in retinal cell cultures and in rat retinas.

scientific article published on 28 February 2006

High glucose enhances intracellular Ca2+ responses triggered by purinergic stimulation in retinal neurons and microglia

scientific article published on 23 December 2009

High glucose induces caspase-independent cell death in retinal neural cells

scientific article published on 16 December 2006

Impact of type 1 diabetes mellitus and sitagliptin treatment on the neuropeptide Y system of rat retina.

scientific article published on 14 February 2018

In Vivo Characterization of Corneal Changes in a Type 1 Diabetic Animal Model

scientific article published on 31 December 2018

Intravitreal injection of adenosine A2A receptor antagonist reduces neuroinflammation, vascular leakage and cell death in the retina of diabetic mice

scientific article published on 20 November 2019

Microglia Contribution to the Regulation of the Retinal and Choroidal Vasculature in Age-Related Macular Degeneration

scientific article published on 14 May 2020

Microglia in Health and Disease: A Double-Edged Sword

scientific article published on 10 September 2017

Modeling Human Glaucoma: Lessons from the in vitro Models

scientific article published on 13 September 2016

NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells

scientific journal article

Neuroprotective Strategies for Retinal Ganglion Cell Degeneration: Current Status and Challenges Ahead

scientific article published on 25 March 2020

Old and new drug targets in diabetic retinopathy: from biochemical changes to inflammation and neurodegeneration

scientific article (publication date: August 2005)

Porous poly(ε-caprolactone) implants: A novel strategy for efficient intraocular drug delivery

scientific article published on 09 November 2019

Role of microglia adenosine A(2A) receptors in retinal and brain neurodegenerative diseases

scientific article

Selective A2A receptor antagonist prevents microglia-mediated neuroinflammation and protects retinal ganglion cells from high intraocular pressure–induced transient ischemic injury

scientific article published on 23 November 2015

Subtle thinning of retinal layers without overt vascular and inflammatory alterations in a rat model of prediabetes.

scientific article

Sweet Stress: Coping With Vascular Dysfunction in Diabetic Retinopathy

scientific article published on 13 July 2018

Tauroursodeoxycholic acid protects retinal neural cells from cell death induced by prolonged exposure to elevated glucose

scientific article published on 5 September 2013

The Adenosinergic System in Diabetic Retinopathy

scientific article

Therapeutic Opportunities for Caffeine and A2A Receptor Antagonists in Retinal Diseases

scientific article

Transient Downregulation of Melanopsin Expression After Retrograde Tracing or Optic Nerve Injury in Adult Rats.

scientific article

Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage

scientific article published on 5 October 2017

c-Src function is necessary and sufficient for triggering microglial cell activation

scientific article

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