List of works by James M. Osborne

A computational study of discrete mechanical tissue models.

scientific article published on 15 April 2009

A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness

scientific article published on 21 December 2020

A two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath

scientific article

An integrative computational model for intestinal tissue renewal.

scientific article published on 20 July 2009

Chaste: Cancer, Heart and Soft Tissue Environment

scientific article published on 13 March 2020

Chaste: an open source C++ library for computational physiology and biology

scientific article

Chaste: using agile programming techniques to develop computational biology software

scientific article

CoGNaC: A Chaste Plugin for the Multiscale Simulation of Gene Regulatory Networks Driving the Spatial Dynamics of Tissues and Cancer

scientific article published on September 2015

Colorectal cancer through simulation and experiment

scientific article

Combined changes in Wnt signaling response and contact inhibition induce altered proliferation in radiation-treated intestinal crypts.

scientific article published on 6 April 2016

Comparing individual-based approaches to modelling the self-organization of multicellular tissues

scientific article

Computational models reveal a passive mechanism for cell migration in the crypt

scientific article (publication date: 2013)

Connecting Models to Data in Multiscale Multicellular Tissue Simulations

scientific article published in 2013

Evaluation of the growth environment of a hydrostatic force bioreactor for preconditioning of tissue-engineered constructs

scientific article

Hydrodynamic dispersion within porous biofilms

scientific article published on 23 January 2013

Implementing vertex dynamics models of cell populations in biology within a consistent computational framework

scientific article published on 09 October 2013

Mechano-logical model of C. elegans germ line suggests feedback on the cell cycle.

scientific article

Modelling Cellular Interactions and Dynamics During Kidney Morphogenesis

scientific article published in 2021

Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt

scientific article published on 03 March 2020

Modelling the role of the basement membrane beneath a growing epithelial monolayer

scientific article

Multiscale Model of Colorectal Cancer Using the Cellular Potts Framework

scientific article published on 4 October 2015

On an infrastructure to support sharing and aggregating pre- and post-publication systems biology research data.

scientific article

On-lattice agent-based simulation of populations of cells within the open-source Chaste framework

scientific article

Reversible host cell remodeling underpins deformability changes in malaria parasite sexual blood stages ⬇️

scientific article published on 11 April 2016

Ten simple rules for a successful cross-disciplinary collaboration

scientific article (publication date: April 2015)

Ten simple rules for effective computational research

scientific article (publication date: March 2014)

The free energy landscape of dimerization of a membrane protein, NanC.

scientific article published on 9 January 2014

The influence of bioreactor geometry and the mechanical environment on engineered tissues.

scientific article published in May 2010

The influence of hydrostatic pressure on tissue engineered bone development

scientific article

The interplay between tissue growth and scaffold degradation in engineered tissue constructs.

scientific article published on 18 September 2012

The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt ⬇️

scientific article

Validity of the Cauchy-Born rule applied to discrete cellular-scale models of biological tissues

scientific article published on 30 April 2013

Paulina is supported by:

About Paulina

Help