List of works - Carlos A. Saura

A role for presenilin 1 in regulating the delivery of amyloid precursor protein to the cell surface

scientific article published in October 2002

ATP and noradrenaline activate CREB in astrocytes via noncanonical Ca(2+) and cyclic AMP independent pathways

scientific article

ApoER2 processing by presenilin-1 modulates reelin expression

scientific article published on 16 December 2013

Bone morphogenetic protein-6 promotes cerebellar granule neurons survival by activation of the MEK/ERK/CREB pathway

scientific article published on December 2009

CREB-regulated transcription coactivator 1-dependent transcription in Alzheimer's disease mice

scientific article

CSF Presenilin-1 complexes are increased in Alzheimer's disease

scientific article published on 06 August 2013

Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice.

scientific article published in July 2005

Conventional and Non-Conventional Roles of Non-Muscle Myosin II-Actin in Neuronal Development and Degeneration

scientific article published on 19 August 2020

Crtc1 activates a transcriptional program deregulated at early Alzheimer's disease-related stages

scientific article (publication date: 23 April 2014)

Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells

scientific article published in October 2003

Estradiol facilitates neurite maintenance by a Src/Ras/ERK signalling pathway

scientific article published on 14 June 2008

Gene expression parallels synaptic excitability and plasticity changes in Alzheimer's disease

scientific article

Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice

scientific article published on 7 August 2009

Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.

scientific article

Loss of presenilin function enhances tau phosphorylation and aggregation in mice

scientific article published on 30 September 2021

Nurr1 protein is required for N-methyl-D-aspartic acid (NMDA) receptor-mediated neuronal survival

scientific article published on 31 January 2012

Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7

scientific article

Presenilin/γ-secretase-dependent EphA3 processing mediates axon elongation through non-muscle myosin IIA

scientific article published on 02 October 2019

Proteolytic Processing of Neurexins by Presenilins Sustains Synaptic Vesicle Release.

scientific article published on 11 December 2017

Ras protein activation is a key event in activity-dependent survival of cerebellar granule neurons.

scientific article published on 12 February 2014

Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice.

scientific article published in September 2004

Short-term environmental enrichment rescues adult neurogenesis and memory deficits in APP(Sw,Ind) transgenic mice

scientific article

Soluble oligomers of amyloid-β peptide disrupt membrane trafficking of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction.

scientific article

Suspended Silicon Microphotodiodes for Electrochemical and Biological Applications

scientific article

The role of CREB signaling in Alzheimer's disease and other cognitive disorders.

scientific article published on January 2011

Triflusal reduces dense-core plaque load, associated axonal alterations and inflammatory changes, and rescues cognition in a transgenic mouse model of Alzheimer's disease.

scientific article published on 10 February 2010

X-linked inhibitor of apoptosis protein negatively regulates neuronal differentiation through interaction with cRAF and Trk.

scientific article published on January 2013

beta-Amyloid disrupts activity-dependent gene transcription required for memory through the CREB coactivator CRTC1.

scientific article published in July 2010

List of works by Carlos A. Saura

A role for presenilin 1 in regulating the delivery of amyloid precursor protein to the cell surface

ATP and noradrenaline activate CREB in astrocytes via noncanonical Ca(2+) and cyclic AMP independent pathways

ApoER2 processing by presenilin-1 modulates reelin expression

Bone morphogenetic protein-6 promotes cerebellar granule neurons survival by activation of the MEK/ERK/CREB pathway

CREB-regulated transcription coactivator 1-dependent transcription in Alzheimer's disease mice

CSF Presenilin-1 complexes are increased in Alzheimer's disease

Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice.

Conventional and Non-Conventional Roles of Non-Muscle Myosin II-Actin in Neuronal Development and Degeneration

Crtc1 activates a transcriptional program deregulated at early Alzheimer's disease-related stages

Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells

Estradiol facilitates neurite maintenance by a Src/Ras/ERK signalling pathway

Gene expression parallels synaptic excitability and plasticity changes in Alzheimer's disease

Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice

Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.

Loss of presenilin function enhances tau phosphorylation and aggregation in mice

Nurr1 protein is required for N-methyl-D-aspartic acid (NMDA) receptor-mediated neuronal survival

Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7

Presenilin/γ-secretase-dependent EphA3 processing mediates axon elongation through non-muscle myosin IIA

Proteolytic Processing of Neurexins by Presenilins Sustains Synaptic Vesicle Release.

Ras protein activation is a key event in activity-dependent survival of cerebellar granule neurons.

Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice.

Short-term environmental enrichment rescues adult neurogenesis and memory deficits in APP(Sw,Ind) transgenic mice

Soluble oligomers of amyloid-β peptide disrupt membrane trafficking of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction.

Suspended Silicon Microphotodiodes for Electrochemical and Biological Applications

The role of CREB signaling in Alzheimer's disease and other cognitive disorders.

Triflusal reduces dense-core plaque load, associated axonal alterations and inflammatory changes, and rescues cognition in a transgenic mouse model of Alzheimer's disease.

X-linked inhibitor of apoptosis protein negatively regulates neuronal differentiation through interaction with cRAF and Trk.

beta-Amyloid disrupts activity-dependent gene transcription required for memory through the CREB coactivator CRTC1.