List of works - Nica Borgese

Formation of stacked ER cisternae by low affinity protein interactions

scientific article

PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins

scientific article

The tale of tail-anchored proteins: coming from the cytosol and looking for a membrane.

scientific article

How tails guide tail-anchored proteins to their destinations.

scientific article published on 16 July 2007

Targeting pathways of C-tail-anchored proteins.

scientific article

Endoplasmic reticulum architecture: structures in flux.

scientific article

Ribosomal-membrane interaction: in vitro binding of ribosomes to microsomal membranes

scientific article published on 01 September 1974

Targeting of a tail-anchored protein to endoplasmic reticulum and mitochondrial outer membrane by independent but competing pathways

scientific article published on August 2001

Unassisted translocation of large polypeptide domains across phospholipid bilayers

scientific article

Transmembrane topogenesis of a tail-anchored protein is modulated by membrane lipid composition

scientific article

Uncovering common principles in protein export of malaria parasites

scientific article published on November 2012

Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein

scientific article

A role for N-myristoylation in protein targeting: NADH-cytochrome b5 reductase requires myristic acid for association with outer mitochondrial but not ER membranes.

scientific article published on December 1996

A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum

scientific article published on 14 December 2009

Mechanism of residence of cytochrome b(5), a tail-anchored protein, in the endoplasmic reticulum.

scientific article published on March 2000

KDEL and KKXX retrieval signals appended to the same reporter protein determine different trafficking between endoplasmic reticulum, intermediate compartment, and Golgi complex

scientific article

N-myristoylation determines dual targeting of mammalian NADH-cytochrome b5 reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning

scientific article published on February 2005

Activation of the endothelial nitric-oxide synthase by tumor necrosis factor-alpha. A novel feedback mechanism regulating cell death

scientific article published on 20 November 2000

Trafficking of tail-anchored proteins: transport from the endoplasmic reticulum to the plasma membrane and sorting between surface domains in polarised epithelial cells.

scientific article published on April 2002

Activation of endothelial nitric-oxide synthase by tumor necrosis factor-alpha: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3' kinase, and Akt.

scientific article published on April 2003

Remote origins of tail-anchored proteins.

scientific article

Nicotine-modulated subunit stoichiometry affects stability and trafficking of α3β4 nicotinic receptor.

scientific article published in July 2013

Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. I. Distribution of the enzyme activity in microsomes, mitochondria, and golgi complex

scientific article published on June 1980

Distribution of the integral membrane protein NADH-cytochrome b5 reductase in rat liver cells, studied with a quantitative radioimmunoblotting assay

scientific article published on October 1986

The role of cytosolic proteins in the insertion of tail-anchored proteins into phospholipid bilayers.

scientific article

Translocation of the C Terminus of a Tail-anchored Protein across the Endoplasmic Reticulum Membrane in Yeast Mutants Defective in Signal Peptide-driven Translocation

scientific article published on 22 November 2002

The effects of Bothrops jararacussu venom and its components on frog nerve-muscle preparation

scientific article published on 01 October 1983

The targeting information of the mitochondrial outer membrane isoform of cytochrome b5 is contained within the carboxyl-terminal region

scientific journal article

Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALS

scientific article published on August 6, 2015

A single mRNA, transcribed from an alternative, erythroid-specific, promoter, codes for two non-myristylated forms of NADH-cytochrome b5 reductase

scientific article published on June 1992

Site of synthesis of rat liver NADH-cytochrome b 5 reductase, an integral membrane protein

scientific article published on 01 April 1980

Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. II. Evidence that a single enzyme accounts for the activity in its various subcellular locations.

scientific article published on June 1980

Getting membrane proteins on and off the shuttle bus between the endoplasmic reticulum and the Golgi complex

scientific article

The specific subcellular localization of two isoforms of cytochrome b5 suggests novel targeting pathways

scientific article published on 01 February 1993

Restructured endoplasmic reticulum generated by mutant amyotrophic lateral sclerosis-linked VAPB is cleared by the proteasome

scientific article published on 18 May 2012

CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1) is a tail-anchored protein in the endoplasmic reticulum (ER) of insulinoma cells

scientific article

Endothelial nitric oxide synthase is segregated from caveolin-1 and localizes to the leading edge of migrating cells

scientific article published on 20 January 2006

A novel point mutation in a 3' splice site of the NADH-cytochrome b5 reductase gene results in immunologically undetectable enzyme and impaired NADH-dependent ascorbate regeneration in cultured fibroblasts of a patient with type II hereditary [...]

scientific article

Basal nitric oxide release attenuates cell migration of HeLa and endothelial cells

scientific article published on 25 June 2009

Chronic deficiency of nitric oxide affects hypoxia inducible factor-1α (HIF-1α) stability and migration in human endothelial cells

scientific article published on 27 December 2011

Tail-anchored Protein Insertion in Mammals: FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR.

scientific article published on 23 May 2016

Three translationally regulated mRNAs are stored in the cytoplasm of clam oocytes

scientific article published in September 1987

Concentration of NADH-cytochrome b5 reductase in erythrocytes of normal and methemoglobinemic individuals measured with a quantitative radioimmunoblotting assay.

scientific article published on November 1987

An erythroid-specific transcript generates the soluble form of NADH-cytochrome b5 reductase in humans

scientific article published in July 1998

A positive signal prevents secretory membrane cargo from recycling between the Golgi and the ER.

scientific article

Rat erythrocyte NADH-cytochrome b5 reductase. Quantitation and comparison between the membrane-bound and soluble forms using an antibody against the rat liver enzyme

scientific article published on 01 November 1982

NADH-cytochrome b5 reductase and cytochrome b5. The problem of posttranslational targeting to the endoplasmic reticulum.

scientific article

Immunological similarity of the NADH-cytochromecelectron transport system in microsomes, Golgi complex and mitochondrial outer membrane of rat liver cells

scientific article published on April 1, 1976

Both the outer mitochondrial membrane and the microsomal forms of cytochrome b5 reductase contain covalently bound myristic acid. Quantitative analysis on the polyvinylidene difluoride-immobilized proteins

scientific article published on March 1990

In vitro synthesis and post-translational insertion into microsomes of the integral membrane protein, NADH-cytochrome b5 oxidoreductase

scientific article published on January 1983

List of works by Nica Borgese

Formation of stacked ER cisternae by low affinity protein interactions

PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins

The tale of tail-anchored proteins: coming from the cytosol and looking for a membrane.

How tails guide tail-anchored proteins to their destinations.

Targeting pathways of C-tail-anchored proteins.

Endoplasmic reticulum architecture: structures in flux.

Ribosomal-membrane interaction: in vitro binding of ribosomes to microsomal membranes

Targeting of a tail-anchored protein to endoplasmic reticulum and mitochondrial outer membrane by independent but competing pathways

Unassisted translocation of large polypeptide domains across phospholipid bilayers

Transmembrane topogenesis of a tail-anchored protein is modulated by membrane lipid composition

Uncovering common principles in protein export of malaria parasites

Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein

A role for N-myristoylation in protein targeting: NADH-cytochrome b5 reductase requires myristic acid for association with outer mitochondrial but not ER membranes.

A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum

Mechanism of residence of cytochrome b(5), a tail-anchored protein, in the endoplasmic reticulum.

KDEL and KKXX retrieval signals appended to the same reporter protein determine different trafficking between endoplasmic reticulum, intermediate compartment, and Golgi complex

N-myristoylation determines dual targeting of mammalian NADH-cytochrome b5 reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning

Activation of the endothelial nitric-oxide synthase by tumor necrosis factor-alpha. A novel feedback mechanism regulating cell death

Trafficking of tail-anchored proteins: transport from the endoplasmic reticulum to the plasma membrane and sorting between surface domains in polarised epithelial cells.

Activation of endothelial nitric-oxide synthase by tumor necrosis factor-alpha: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3' kinase, and Akt.

Remote origins of tail-anchored proteins.

Nicotine-modulated subunit stoichiometry affects stability and trafficking of α3β4 nicotinic receptor.

Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. I. Distribution of the enzyme activity in microsomes, mitochondria, and golgi complex

Distribution of the integral membrane protein NADH-cytochrome b5 reductase in rat liver cells, studied with a quantitative radioimmunoblotting assay

The role of cytosolic proteins in the insertion of tail-anchored proteins into phospholipid bilayers.

Translocation of the C Terminus of a Tail-anchored Protein across the Endoplasmic Reticulum Membrane in Yeast Mutants Defective in Signal Peptide-driven Translocation

The effects of Bothrops jararacussu venom and its components on frog nerve-muscle preparation

The targeting information of the mitochondrial outer membrane isoform of cytochrome b5 is contained within the carboxyl-terminal region

Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALS

A single mRNA, transcribed from an alternative, erythroid-specific, promoter, codes for two non-myristylated forms of NADH-cytochrome b5 reductase

Site of synthesis of rat liver NADH-cytochrome b 5 reductase, an integral membrane protein

Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. II. Evidence that a single enzyme accounts for the activity in its various subcellular locations.

Getting membrane proteins on and off the shuttle bus between the endoplasmic reticulum and the Golgi complex

The specific subcellular localization of two isoforms of cytochrome b5 suggests novel targeting pathways

Restructured endoplasmic reticulum generated by mutant amyotrophic lateral sclerosis-linked VAPB is cleared by the proteasome

CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1) is a tail-anchored protein in the endoplasmic reticulum (ER) of insulinoma cells

Endothelial nitric oxide synthase is segregated from caveolin-1 and localizes to the leading edge of migrating cells

A novel point mutation in a 3' splice site of the NADH-cytochrome b5 reductase gene results in immunologically undetectable enzyme and impaired NADH-dependent ascorbate regeneration in cultured fibroblasts of a patient with type II hereditary [...]

Basal nitric oxide release attenuates cell migration of HeLa and endothelial cells

Chronic deficiency of nitric oxide affects hypoxia inducible factor-1α (HIF-1α) stability and migration in human endothelial cells

Tail-anchored Protein Insertion in Mammals: FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR.

Three translationally regulated mRNAs are stored in the cytoplasm of clam oocytes

Concentration of NADH-cytochrome b5 reductase in erythrocytes of normal and methemoglobinemic individuals measured with a quantitative radioimmunoblotting assay.

An erythroid-specific transcript generates the soluble form of NADH-cytochrome b5 reductase in humans

A positive signal prevents secretory membrane cargo from recycling between the Golgi and the ER.

Rat erythrocyte NADH-cytochrome b5 reductase. Quantitation and comparison between the membrane-bound and soluble forms using an antibody against the rat liver enzyme

NADH-cytochrome b5 reductase and cytochrome b5. The problem of posttranslational targeting to the endoplasmic reticulum.

Immunological similarity of the NADH-cytochromecelectron transport system in microsomes, Golgi complex and mitochondrial outer membrane of rat liver cells

Both the outer mitochondrial membrane and the microsomal forms of cytochrome b5 reductase contain covalently bound myristic acid. Quantitative analysis on the polyvinylidene difluoride-immobilized proteins

In vitro synthesis and post-translational insertion into microsomes of the integral membrane protein, NADH-cytochrome b5 oxidoreductase